Bumetanide combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 10/14/2005 63 Male 359 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2000 76 Female 2/23/2006 Lawyer United States
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Disability 6/14/2007 75 Female 168 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Back Pain 7/2/2007 63 Male 322 lb 9/20/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2008 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2008 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2009 Female 154 lb 4/27/2009 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palpitations Hospitalization 5/26/2009 69 6/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 5/17/2009 72 Male 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Death 72 Female 8/10/2009 United States
Primary
Concomitant
Weight Increased Other Serious 31 Male 9/15/2009 United States
Primary
Concomitant
Sepsis Life Threatening Female 9/24/2009 Physician Ireland
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 62 Male 6/17/2010 Physician United Kingdom
Primary
Concomitant
Overdose Other Serious 5/1/2010 74 Male 197 lb 7/30/2010 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity 1/1/2009 75 Female 225 lb 7/31/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/13/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 74 Male 197 lb 8/19/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/27/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 62 Male 9/24/2010 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/1/2009 30 Male 221 lb 9/24/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 7/15/2010 76 Female 110 lb 9/28/2010 Ireland
Primary
Concomitant
Overdose Other Serious 74 Male 197 lb 10/5/2010 Consumer United States
Primary
Secondary
Concomitant
Overdose Other Serious 74 Male 197 lb 10/12/2010 Consumer United States
Primary
Secondary
Concomitant
Haematemesis Death 10/17/2010 61 Male 10/21/2010 Physician United Kingdom
Primary
Concomitant
Cardiac Valve Disease Hospitalization 90 Male 11/1/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 9/27/2010 72 Male 232 lb 11/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 9/30/2010 63 Male 344 lb 11/23/2010 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/19/2010 69 Female 12/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Required Intervention 12/9/2010 72 Male 12/9/2010 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sensation Of Foreign Body Hospitalization Female 223 lb 12/22/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 9/5/2010 69 Female 12/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/5/2010 69 Female 1/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 10/1/2010 69 Female 1/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mobility Decreased Disability 10/1/2010 69 Female 1/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 78 Female 1/5/2011 United States
Primary
Concomitant
Nasopharyngitis 9/1/2010 75 Female 1/30/2011 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 54 Female 2/11/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Gastric Cancer Death Male 2/14/2011 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 1/24/2011 72 Male 2/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Off Label Use Other Serious 73 Female 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Hospitalization 1/24/2011 72 Male 3/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 12/17/2010 69 Female 154 lb 3/29/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/19/2011 80 Male 3/22/2011 Other Health Professional
Primary
Concomitant
Injury Other Serious 1/31/2007 72 Male 205 lb 4/4/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 1/31/2007 72 Male 205 lb 4/4/2011 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Other Serious 82 Female 4/11/2011 Physician United Kingdom
Primary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/31/2007 72 Male 205 lb 4/26/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Hospitalization 4/7/2011 63 Male 218 lb 4/27/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Death 8/29/2001 70 Male 190 lb 5/3/2011 Lawyer United States
Primary
Concomitant
Blood Creatinine Increased Disability 9/5/2010 69 Female 8/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthenia Disability 10/1/2010 69 Female 8/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthenia Disability 9/5/2010 69 Female 8/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Death Death 3/4/2011 79 Male 141 lb 8/4/2011 Physician Belgium
Primary
Concomitant
Asthenia Life Threatening 10/1/2010 69 Female 8/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Life Threatening 9/5/2010 69 Female 8/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 10/1/2010 69 Female 8/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 5/18/2011 51 Female 211 lb 8/11/2011 Physician United Kingdom
Primary
Concomitant
Arteriosclerosis Coronary Artery Death 6/2/2009 80 Male 8/11/2011 Consumer United Kingdom
Primary
Concomitant
Pneumothorax Other Serious 6/1/2010 73 Male 8/29/2011 Physician Norway
Primary
Concomitant
Fear Hospitalization 1/31/2007 72 Male 205 lb 9/7/2011 Consumer United States
Primary
Concomitant
Fear Hospitalization 1/31/2007 72 Male 205 lb 9/7/2011 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 12/2/2011 89 Male 12/27/2011 Other Health Professional Ireland
Primary
Concomitant
Asthenia Hospitalization 4/1/2011 85 Male 1/24/2012 Consumer Norway
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/1/2011 85 Male 1/25/2012 Other Health Professional Norway
Primary
Secondary
Concomitant
Nausea Hospitalization 4/1/2011 85 Male 1/25/2012 Physician Norway
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 1/1/2012 96 Female 3/30/2012 Other Health Professional Norway
Primary
Secondary
Concomitant
Sick Sinus Syndrome Death 72 Female 169 lb 6/11/2012 Consumer United States
Primary
Concomitant
Nausea Other Serious 1/1/2012 96 Female 6/14/2012 Other Health Professional Norway
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 6/8/2012 79 Male 147 lb 8/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Febrile Neutropenia Life Threatening 5/17/2010 66 Male 12/5/2012 Physician Us
Primary
Secondary
Concomitant
Right Ventricular Dysfunction Other Serious 5/11/2010 69 Male 12/21/2012 Physician No
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious Female 143 lb 9/25/2012 Lawyer Us
Primary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 8/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 10/24/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/2/2012 79 Female 122 lb 6/20/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Cerebral Haematoma Hospitalization 7/24/2012 58 Female 253 lb 8/30/2012 Other Health Professional Gb
Primary
Concomitant
Oedema Other Serious 7/17/2012 51 Male 9/2/2012 Other Health Professional Gb
Primary
Concomitant
Enuresis 8/1/2012 86 Male 141 lb 10/1/2012 Other Health Professional Gb
Primary
Concomitant
Hypoglycaemia Hospitalization 9/4/2012 67 Male 9/27/2012 Physician Us
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/12/2012 88 Male 9/18/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Terminal State Death 50 Female 11/26/2012 Physician Gb
Primary
Concomitant
Left Ventricular Failure Death Male 216 lb 10/15/2012 Physician Ie
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/11/2012 88 Male 9/25/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Tongue Ulceration Other Serious 86 Male 4/19/2013 Other Health Professional Gb
Primary
Concomitant
Interacting
Tongue Ulceration Other Serious 86 Male 10/12/2012 Physician Gb
Primary
Concomitant
Interacting
Chest Pain 10/10/2012 69 Male 320 lb 10/18/2012 Consumer Us
Primary
Concomitant
Foot Fracture Hospitalization 10/4/2012 68 Male 10/23/2012 Physician Us
Primary
Concomitant
Pulmonary Oedema Other Serious 9/1/2012 21 Female 11/5/2012 Physician Gb
Primary
Concomitant
Tongue Ulceration Other Serious 86 Male 11/2/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/18/2011 79 Male 11/2/2012 Physician Be
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/2/2012 79 Female 11/8/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Plasma Cell Myeloma Death 7/31/2012 81 Male 171 lb 12/27/2012 Physician Us
Primary
Concomitant
Death Hospitalization 7/2012 Male 12/18/2012 Pharmacist Us
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/17/2010 66 Male 1/2/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Hallucination, Auditory Other Serious 11/2012 85 Female 183 lb 1/11/2013 Consumer Us
Primary
Concomitant
Toxicity To Various Agents Death 9/3/2012 74 Male 12/13/2012 Pharmacist Us
Primary
Concomitant
Pneumonia Hospitalization 1/5/2013 72 Female 1/29/2013 Consumer Us
Primary
Concomitant
Vomiting Hospitalization 50 Male 1/30/2013 Physician Us
Primary
Concomitant
Hyperthyroidism Other Serious 72 Male 2/15/2013 Country Not Specified
Primary
Concomitant
Hypoglycaemia Other Serious 12/2012 84 Male 1/31/2013 Other Health Professional Gb
Primary
Concomitant
Oedema Peripheral Hospitalization 2/7/2013 80 Male 2/21/2013 Other Health Professional Us
Primary
Concomitant
Septic Shock Death 2/1/2013 50 Female 3/8/2013 Pharmacist Us
Primary
Concomitant
Urosepsis Other Serious 9/29/2012 68 Male 271 lb 4/25/2013 Other Health Professional Gb
Primary
Concomitant
Cardiac Failure Death 65 Male 4/25/2013 Pharmacist Us
Primary
Concomitant
Circulatory Collapse Hospitalization 5/19/2003 53 Male 5/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 5/19/2003 51 Male 5/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 4/25/2013 78 Female 260 lb 5/21/2013 Other Health Professional Gb
Primary
Concomitant
Circulatory Collapse Hospitalization 5/19/2003 51 Male 5/22/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Medication Residue Present 2012 Female 150 lb 5/30/2013 Consumer Us
Primary
Concomitant
Therapy Cessation Death 3/21/2013 84 Male 177 lb 6/13/2013 Other Health Professional Gb
Primary
Concomitant
Oedema Peripheral Hospitalization 4/1/2009 72 Female 7/27/2013 Consumer Fr
Primary
Secondary
Concomitant
Melaena Hospitalization 7/13/2013 81 Male 187 lb 7/31/2013 Physician Gb
Primary
Concomitant
Renal Failure Hospitalization Male 8/1/2013 Physician Us
Primary
Concomitant
Melaena Hospitalization 7/13/2013 81 Male 187 lb 8/12/2013 Other Health Professional Gb
Primary
Concomitant
Oedema Peripheral Hospitalization 4/1/2009 72 Female 8/14/2013 Consumer Gb
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/1/2009 72 Female 8/17/2013 Consumer Fr
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/1/2009 72 Female 8/20/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/1/2009 72 Female 8/20/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/1/2013 69 Male 280 lb 8/28/2013 Other Health Professional Gb
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/5/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Headache Life Threatening 8/14/2013 65 Female 115 lb 9/7/2013 Other Health Professional Gb
Primary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/10/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Interacting
Weight Bearing Difficulty Life Threatening 8/17/2013 73 Male 9/6/2013 Consumer Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/13/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/16/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/2013 71 Female 139 lb 9/17/2013 Consumer Us
Primary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/17/2013 Consumer Gb
Primary
Secondary
Concomitant

Drug Data