Bumetanide combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 9/1/2005 78 Male 1/19/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 1/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
Somnolence Life Threatening 11/21/2005 85 Female 143 lb 1/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Failure Required Intervention 12/1/2005 Female 2/8/2006 Physician Netherlands
Primary
Concomitant
Renal Impairment Other Serious 78 Male 2/13/2006 Netherlands
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2000 76 Female 2/23/2006 Lawyer United States
Primary
Concomitant
Myocardial Ischaemia Death 62 Male 2/22/2006 Physician United Kingdom
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Laceration Hospitalization 11/29/2005 Female 154 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 1/30/2006 87 Male 3/1/2006 Pharmacist Ireland
Primary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 2/23/2002 46 Male 3/22/2006 Physician United States
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious Female 4/20/2006 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 11/20/2005 58 Female 113 lb 11/22/2005 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 5/12/2006 Physician Netherlands
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 47 Female 123 lb 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 6/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/22/2005 57 Female 143 lb 6/23/2006 Belgium
Primary
Concomitant
Viral Infection Death 6/13/2006 66 Male 152 lb 6/30/2006 Physician Netherlands
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2002 73 Female 6/28/2006 Physician United Kingdom
Primary
Concomitant
Pruritus Other Serious 1/1/2002 73 Female 6/28/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 74 Male 7/3/2006 United States
Primary
Concomitant
Pancytopenia Required Intervention 74 Male 7/5/2006 Physician United States
Primary
Concomitant
Throat Tightness Hospitalization 10/13/2005 49 Female 157 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/24/2006 71 Female 146 lb 7/20/2006 Netherlands
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 7/31/2006 United Kingdom
Primary
Secondary
Renal Failure Hospitalization 5/3/2006 91 Female 8/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Other Serious 1/1/2004 Male 230 lb 8/8/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 91 Female 8/3/2006 United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 8/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 8/4/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 8/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 3/5/2006 91 Female 8/21/2006 Denmark
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 9/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis 4/1/2006 49 Male 173 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Blood Amylase Increased Other Serious 5/1/2005 78 Male 9/5/2006 United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 9/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 9/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 9/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/3/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 10/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Cardiac Failure Congestive Other Serious 75 Female 133 lb 10/10/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 5/3/2006 91 Female 10/9/2006 Germany
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 10/17/2006 United Kingdom
Primary
Secondary
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 10/20/2006 Consumer United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 1/1/2006 91 Female 10/12/2006 United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 10/13/2006 United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 10/12/2006 United Kingdom
Primary
Secondary
Renal Failure Hospitalization 5/3/2006 91 Female 10/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 10/26/2006 United Kingdom
Primary
Secondary
Vasoconstriction Other Serious 54 Male 150 lb 11/6/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 10/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Right Ventricular Failure Hospitalization 43 Male 11/15/2006 Physician Netherlands
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 11/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Other Serious 9/4/2006 36 Female 12/7/2006 Belgium
Primary
Concomitant
Loss Of Consciousness Other Serious 11/21/2006 51 Male 12/13/2006 Pharmacist Netherlands
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 12/18/2006 Other Health Professional Netherlands
Primary
Concomitant
Dry Throat 1/1/2006 47 Female 130 lb 10/24/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 12/20/2006 72 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dizziness Hospitalization 10/10/2006 Male 206 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Skin Discolouration Disability 55 Female 163 lb 2/20/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Skin Discolouration Disability 1/1/2004 56 Female 163 lb 2/20/2007 Netherlands
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/27/2006 64 Male 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 2/1/2007 45 Female 134 lb 2/23/2007 Other Health Professional United States
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 2/21/2007 Other Health Professional Netherlands
Primary
Concomitant
Skin Discolouration Disability 1/1/2004 55 Female 163 lb 2/22/2007 Consumer Netherlands
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/2/2007 Consumer United States
Primary
Concomitant
Skin Discolouration Disability 1/1/2004 Female 3/2/2007 Consumer France
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 54 Male 150 lb 3/12/2007 United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/12/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/6/2007 45 Female 134 lb 3/28/2007 Consumer United States
Primary
Concomitant
Angioedema Life Threatening 3/6/2007 69 Male 152 lb 4/16/2007 Physician United Kingdom
Primary
Concomitant
Mean Arterial Pressure Decreased Other Serious 3/1/2007 73 Male 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/28/2007 75 Male 4/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dermatosis 77 Female 5/3/2007 Netherlands
Primary
Concomitant
Skin Lesion Other Serious 77 Female 5/3/2007 Other Health Professional Netherlands
Primary
Concomitant
White Blood Cells Urine Positive Other Serious 7/17/2006 Male 5/18/2007 Physician Belgium
Primary
Concomitant
Vomiting Other Serious 3/25/2006 Female 115 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neck Pain Disability 86 220 lb 7/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 11/1/2005 75 Female 7/17/2007 Other Health Professional China
Primary
Concomitant
Interacting
Neck Pain Disability 86 220 lb 7/18/2007 United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 7/17/2007 United Kingdom
Primary
Secondary
Insomnia 6/13/2007 76 Male 325 lb 7/10/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 8/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Hospitalization 5/3/2006 91 Female 8/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Disability 6/14/2007 75 Female 168 lb 9/26/2007 United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Disability 6/14/2007 75 Female 168 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/1/2007 76 Female 197 lb 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Photosensitivity Reaction Other Serious 50 Male 209 lb 11/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2005 Female 223 lb 12/14/2007 Consumer United States
Primary
Concomitant
Urine Odour Abnormal Other Serious 11/1/2007 Female 153 lb 12/19/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Acute Death 75 Female 1/23/2008 Physician Netherlands
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Polymyositis Hospitalization 12/1/2006 77 Male 2/18/2008 Other Health Professional Norway
Primary
Concomitant
Oedema Peripheral Life Threatening 9/20/2007 73 Female 3/4/2008 Pharmacist United States
Primary
Concomitant
Chest Pain Other Serious 4/5/2006 69 Male 2/28/2008 Netherlands
Primary
Concomitant
Angina Pectoris Hospitalization 3/6/2008 66 Female 251 lb 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 68 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Swollen Tongue Life Threatening 2/23/2008 69 Male 116 lb 4/17/2008 Pharmacist United States
Primary
Secondary
Concomitant
Mean Arterial Pressure Decreased Other Serious 3/1/2007 73 Male 5/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/31/2008 80 Male 4/17/2008 United Kingdom
Primary
Concomitant
Syncope Life Threatening 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 143 lb 5/16/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Syncope Other Serious 83 Female 6/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Hospitalization 5/1/2008 Male 287 lb 6/13/2008 Physician United States
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 83 Female 143 lb 6/10/2008
Primary
Secondary
Concomitant
Respiratory Failure Death 55 Female 6/30/2008 Belgium
Primary
Concomitant
Hypomagnesaemia Other Serious 11/1/2006 78 Female 7/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious 73 Male 8/5/2008 Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 78 Female 8/3/2008 United Kingdom
Primary
Concomitant
Hepatitis Acute Hospitalization 7/17/2008 78 Female 139 lb 8/15/2008 Consumer Belgium
Primary
Concomitant
Vomiting Other Serious 78 Female 8/8/2008 United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2008 42 Female 144 lb 9/4/2008 United States
Primary
Concomitant
Muscle Disorder Other Serious 11/1/2006 78 Female 9/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Disorder Other Serious 11/1/2006 78 Female 9/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 62 Female 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 78 Female 10/8/2008 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 9/8/2008 Male 10/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 78 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Disorder Other Serious 11/1/2006 78 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 78 Female 10/23/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 78 Female 10/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/5/2006 91 Female 10/22/2008 Denmark
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 5/3/2006 91 Female 10/22/2008 Denmark
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Death Death 9/3/2008 Male 12/19/2008 Physician Netherlands
Primary
Concomitant

Drug Data