Bumetanide combined with Metolazone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Disorder Other Serious 1/1/2005 76 Male 1/4/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/12/2006 Female 175 lb 6/8/2006 Consumer
Primary
Concomitant
Viraemia Hospitalization 6/7/2006 Male 28 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/2/2006 Female 32 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Stomach Scan Abnormal 12/8/2005 67 Male 11/13/2006 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 10/27/2006 64 Male 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 2/1/2007 45 Female 134 lb 2/23/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/2/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/12/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/6/2007 45 Female 134 lb 3/28/2007 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 3/20/2007 Male 208 lb 4/2/2007 Pharmacist United States
Primary
Secondary
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/18/2007 46 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Hospitalization 9/1/2007 Male 255 lb 9/28/2007 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 7/10/2007 51 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gout Hospitalization 10/27/2003 73 Female 12/4/2007 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 8/15/2006 64 Female 12/5/2007 United States
Primary
Concomitant
Myoclonus Required Intervention 1/29/2006 65 Male 12/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 1/29/2006 65 Male 12/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Deafness Disability 10/25/2007 70 Female 234 lb 12/27/2007 Pharmacist United States
Primary
Concomitant
Myoclonus Hospitalization 1/1/2006 65 Male 1/30/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/27/2008 2/9/2008 Pharmacist United States
Primary
Secondary
Vomiting Hospitalization 1/27/2008 63 Male 2/13/2008 Pharmacist United States
Primary
Secondary
Tachycardia Other Serious 68 Male 5/13/2008 Physician United States
Primary
Concomitant
Oral Intake Reduced Hospitalization Male 5/13/2008 United States
Primary
Concomitant
Hypokalaemia Hospitalization 6/10/2008 63 Male 281 lb 6/16/2008 Pharmacist United States
Primary
Secondary
Oedema Peripheral Hospitalization 9/1/2007 Male 255 lb 7/1/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 6/18/2007 46 Male 7/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/1/2007 Male 255 lb 7/28/2008 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/17/2007 Female 166 lb 7/30/2008 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/8/2008 Male 10/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 76 Male 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 10/23/2008 69 Female 1/12/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/15/2008 Female 154 lb 2/2/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 2/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Scab Hospitalization 66 Male 2/28/2009 United States
Primary
Concomitant
Weight Decreased Other Serious Male 326 lb 3/24/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 66 Male 4/7/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 66 Male 5/1/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/3/2009 57 Male 5/12/2009 Pharmacist United States
Primary
Secondary
Weight Decreased Hospitalization 4/28/2008 65 Male 5/24/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 65 Male 6/5/2009 United States
Primary
Concomitant
Vertigo Hospitalization 4/28/2008 65 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Renal Disorder Hospitalization 4/28/2008 65 Male 7/7/2009 United States
Primary
Concomitant
Hypokalaemia Hospitalization 7/3/2009 36 Male 7/20/2009 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 85 Female 8/3/2009 United States
Primary
Concomitant
Flushing 8/1/2008 Male 265 lb 8/24/2009 United States
Primary
Concomitant
Unevaluable Event Death Female 8/20/2009 United States
Primary
Concomitant
Weight Increased Other Serious 7/22/2008 69 Male 8/27/2009 Physician United States
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Required Intervention 11/8/2008 72 Female 234 lb 11/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 9/4/2009 42 Male 9/29/2009 Other Health Professional United States
Primary
Concomitant
Nervous System Disorder Other Serious 7/22/2008 69 Male 10/6/2009 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 9/4/2009 42 Male 10/14/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization Female 10/18/2009 United States
Primary
Concomitant
Social Problem Hospitalization Female 11/3/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 72 Female 12/2/2009 United States
Primary
Concomitant
Hyponatraemia Other Serious 1/1/2009 64 Male 268 lb 12/16/2009 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 72 Female 12/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 66 Male 2/5/2010 Consumer United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Cardiac Arrest Death 2/25/2009 Female 3/12/2010 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 75 Female 4/8/2010 United States
Primary
Concomitant
Skin Necrosis Life Threatening 60 Female 132 lb 4/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/24/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 60 Female 4/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 75 Female 4/21/2010 Lawyer United States
Primary
Concomitant
Skin Necrosis Life Threatening 60 Female 132 lb 4/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Onset Of Sleep 10/1/2008 76 Female 5/3/2010 Consumer
Primary
Concomitant
Skin Cancer Other Serious 4/18/2010 87 Female 170 lb 5/6/2010 United States
Primary
Concomitant
Skin Necrosis Other Serious 60 Female 132 lb 5/3/2010 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 5/18/2010 Lawyer United States
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 4/18/2010 87 Female 170 lb 5/24/2010 United States
Primary
Concomitant
Renal Failure Acute Required Intervention 11/13/2009 64 Male 162 lb 5/7/2010 Pharmacist United States
Primary
Secondary
Death Death 4/29/2010 79 Male 6/9/2010 Consumer United States
Primary
Concomitant
Skin Necrosis Other Serious 4/10/2010 60 Female 132 lb 6/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Life Threatening 4/10/2010 60 Female 132 lb 6/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Life Threatening 4/10/2010 60 Female 132 lb 6/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Skin Necrosis Other Serious 60 Female 132 lb 6/21/2010 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 4/29/2010 79 Male 7/20/2010 Other Health Professional United States
Primary
Concomitant
Sleep Disorder 2/1/2008 65 Male 211 lb 7/21/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 7/26/2010 United States
Primary
Concomitant
Skin Burning Sensation Other Serious 4/1/2010 87 Female 170 lb 8/4/2010 Consumer United States
Primary
Concomitant
Erythema Other Serious 3/18/2008 42 Male 368 lb 8/11/2010 Lawyer United States
Primary
Concomitant
Sudden Death Death 9/4/2009 42 Male 8/13/2010 Other Health Professional United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/24/2010 65 Male 167 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 28 Male 198 lb 9/9/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 12/15/2009 65 Male 316 lb 1/25/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 9/10/2010 United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 29 Male 198 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Test Abnormal Hospitalization Female 129 lb 10/6/2010 Consumer United States
Primary
Concomitant
Erythema Other Serious 3/18/2008 42 Male 368 lb 10/6/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 29 Male 10/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 9/21/2010 83 Male 10/20/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening Male 10/26/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization Female 10/27/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening Male 11/11/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 78 Male 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious Male 12/1/2010 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Other Serious 78 Male 11/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization Female 11/30/2010 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Upper Respiratory Tract Infection 1/1/2010 12/22/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Pain Death 8/29/2001 70 Male 190 lb 5/3/2011 Lawyer United States
Primary
Concomitant
Drop Attacks Other Serious 6/1/2008 28 Male 198 lb 5/13/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/12/2011 64 Male 357 lb 5/17/2011 Pharmacist United States
Primary
Secondary
Drop Attacks Death 6/1/2008 28 Male 198 lb 5/20/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 4/17/2011 5/26/2011 Physician United States
Primary
Concomitant
Schizophrenia Death 6/1/2008 28 Male 198 lb 6/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 6/1/2008 28 Male 198 lb 6/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 4/17/2011 6/3/2011 Physician United States
Primary
Concomitant
Myoclonus Other Serious 6/1/2008 29 Male 6/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 5/31/2011 66 Female 6/3/2011 Pharmacist United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/9/2011 Consumer United States
Primary
Concomitant
Death Death 5/6/2011 66 Female 6/9/2011 Pharmacist United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/16/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/1/2008 29 Male 6/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Generalised Oedema Other Serious 3/1/2011 77 Female 6/23/2011 Pharmacist United States
Primary
Concomitant
Implantable Pleural Catheter Insertion Life Threatening 4/17/2011 7/14/2011 Physician United States
Primary
Concomitant
Flushing 1/1/2010 67 Male 313 lb 8/5/2011 Consumer United States
Primary
Concomitant
Ocular Vascular Disorder Other Serious 9/20/2011 10/4/2011 Pharmacist United States
Primary
Concomitant
Oedema Other Serious 4/1/2007 61 Male 10/14/2011 United States
Primary
Concomitant
Carotid Artery Stenosis Other Serious 9/20/2011 10/17/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Other Serious 71 Female 10/18/2011 Consumer United States
Primary
Interacting
Visual Impairment Other Serious 71 Female 10/19/2011 Consumer United States
Primary
Interacting
Nasal Disorder Other Serious 71 Female 10/20/2011 Consumer United States
Primary
Interacting
Diarrhoea Other Serious 71 Female 10/20/2011 Other Health Professional United States
Primary
Secondary
Eye Oedema Other Serious 71 Female 10/21/2011 Consumer United States
Primary
Secondary
Mental Impairment Other Serious 71 Female 11/2/2011 Consumer United States
Primary
Secondary
Haematoma Hospitalization 3/3/2010 67 Female 11/11/2011 Physician United States
Primary
Concomitant
Blood Electrolytes Abnormal Other Serious 71 Female 11/17/2011 Consumer United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 2/9/2008 75 Female 180 lb 11/29/2011 Lawyer United States
Primary
Concomitant
Raynaud's Phenomenon Other Serious 12/9/2011 78 Female 12/29/2011 Consumer United States
Primary
Concomitant

Drug Data