Bumetanide combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Life Threatening 11/21/2005 85 Female 143 lb 1/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Death 4/25/2005 76 Female 113 lb 2/7/2006 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/28/2004 64 Female 174 lb 2/8/2006 Other Health Professional Belgium
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization Female 2/16/2006 Ireland
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/20/2003 58 Male 3/29/2006 France
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/2/2006 Female 331 lb 5/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 11/20/2005 58 Female 113 lb 11/22/2005 Pharmacist United States
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 5/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 47 Female 123 lb 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 145 lb 5/25/2006 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 6/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Death 3/1/2006 53 Female 6/21/2006 United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 145 lb 8/1/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 6/10/2006 58 Female 198 lb 8/16/2006 Physician Belgium
Primary
Secondary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious Female 154 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 9/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 9/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 9/7/2006 65 Female 10/2/2006 United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 207 lb 10/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Knee Arthroplasty Required Intervention 8/14/2006 80 Female 139 lb 10/23/2006 Physician United States
Primary
Concomitant
Upper Limb Fracture Life Threatening Female 12/15/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 12/18/2006 Other Health Professional Netherlands
Primary
Concomitant
Upper Limb Fracture Other Serious 83 Female 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 12/15/2006 Female 132 lb 1/30/2007 Physician France
Primary
Concomitant
Upper Limb Fracture Life Threatening Female 2/20/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 2/21/2007 Other Health Professional Netherlands
Primary
Concomitant
Pancreatitis Acute Hospitalization 58 Female 8/21/2004 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 12/1/2006 68 Female 165 lb 4/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Required Intervention 12/14/2006 54 Male 12/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 12/1/2006 68 Female 165 lb 4/11/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Death 1/14/2007 70 Female 4/2/2007 Norway
Primary
Concomitant
Rash Pruritic Hospitalization 3/24/2007 75 Male 4/25/2007 United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 4/26/2007 United Kingdom
Primary
Concomitant
Dermatosis 77 Female 5/3/2007 Netherlands
Primary
Concomitant
Neuropathy Peripheral 9/27/2006 48 Female 10/23/2006 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 77 Female 5/3/2007 Other Health Professional Netherlands
Primary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Headache Hospitalization 3/12/2007 65 Female 229 lb 6/1/2007 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 6/14/2006 52 Female 160 lb 4/4/2007 United States
Primary
Concomitant
Vomiting Other Serious 3/25/2006 Female 115 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 75 Male 5/31/2007 United Kingdom
Primary
Concomitant
Insomnia Other Serious 5/2/2007 38 Female 7/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 5/2/2007 38 Female 7/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 5/2/2007 38 Female 7/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 5/2/2007 38 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/24/2007 Male 9/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Muscle Spasms 9/14/2006 52 Female 335 lb 9/20/2007 Other Health Professional United States
Primary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/10/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/12/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/15/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 73 Female 10/19/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Lung Transplant Other Serious 53 Female 112 lb 10/16/2007 Other Health Professional Belgium
Primary
Concomitant
Small Intestinal Perforation Death 10/3/2007 Female 134 lb 10/29/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 10/1/2006 53 Female 112 lb 10/30/2007 Other Health Professional Belgium
Primary
Concomitant
Small Intestinal Perforation Death 10/3/2007 Female 134 lb 11/2/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Purpura Life Threatening 5/2/1998 38 Female 119 lb 11/12/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Purpura Life Threatening 5/2/1998 38 Female 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization 9/28/2007 Female 11/29/2007 Other Health Professional Norway
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 2/1/2008 Consumer United States
Primary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 2/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Necrosis Life Threatening 4/2/2006 Female 331 lb 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 3/19/2008 Consumer United States
Primary
Concomitant
Skin Necrosis Life Threatening 4/2/2006 Female 331 lb 3/28/2008 Consumer
Primary
Secondary
Concomitant
Vasculitis Other Serious 12/1/2007 57 Female 4/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 4/7/2008 Physician United States
Primary
Concomitant
Drug Effect Decreased Hospitalization 8/5/2007 88 Female 5/7/2008 Physician United States
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/2004 Female 6/13/2008 France
Primary
Concomitant
Gallbladder Cancer Life Threatening 4/30/2008 Male 192 lb 6/27/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 6/15/2008 63 Female 7/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 6/15/2008 63 Female 7/2/2008 United Kingdom
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 7/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2008 79 Female 196 lb 7/10/2008 Physician Germany
Primary
Secondary
Concomitant
Ulcer 6/15/2008 63 Female 7/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2008 79 Female 196 lb 7/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2006 53 Female 7/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Disability 9/12/2007 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Sleep Disorder Female 8/20/2008 Consumer United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2008 79 Female 196 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased 12/1/2007 Female 117 lb 9/12/2008 Physician United States
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/24/2007 Male 9/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/25/2008
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 10/2/2008 Consumer United States
Primary
Secondary
Concomitant
No Adverse Event Male 10/3/2008 Other Health Professional France
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 8/13/2008 78 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 63 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 76 Male 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2007 34 Female 11/18/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Hypothyroidism 8/28/2008 Male 225 lb 11/26/2008 United States
Primary
Concomitant
Melanosis Coli Other Serious 71 Male 11/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 12/10/2008 Consumer United States
Primary
Secondary
Concomitant
Joint Swelling 9/3/2008 Female 195 lb 12/12/2008 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 172 lb 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 5/1/2006 49 Female 12/31/2008 Lawyer United States
Primary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Death 71 Male 1/27/2009 France
Primary
Secondary
Concomitant
Pyrexia Death 71 Male 1/27/2009 France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 11/24/2008 84 Male 162 lb 2/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 2/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 172 lb 2/26/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Death 71 Male 2/16/2009 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/17/2009 Male 4/8/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 66 Male 4/7/2009 United States
Primary
Concomitant
Aplastic Anaemia Disability 5/23/2007 81 Female 4/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aplastic Anaemia Disability 5/23/2007 81 Female 5/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Disability 5/23/2007 81 Female 4/27/2009
Primary
Secondary
Concomitant
Aplastic Anaemia Disability 5/23/2007 81 Female 4/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/17/2002 Male 306 lb 5/4/2009 Physician United Kingdom
Primary
Concomitant
Somnolence Hospitalization 8/16/2007 64 Female 128 lb 5/1/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 66 Male 5/1/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 66 Female 5/6/2009 United Kingdom
Primary
Concomitant
Oedema Other Serious 5/2/2007 38 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/25/2009 66 Female 5/12/2009 United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 4/4/2007 Male 194 lb 5/20/2009 Physician Belgium
Primary
Concomitant
Oedema Life Threatening 5/2/2007 38 Female 6/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 5/2/2007 38 Female 132 lb 6/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 4/28/2008 65 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Renal Disorder Hospitalization 4/28/2008 65 Male 7/7/2009 United States
Primary
Concomitant
Uterine Polyp Other Serious 4/1/2009 Male 184 lb 7/24/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 4/1/2009 Male 184 lb 7/27/2009 Physician United States
Primary
Concomitant
Off Label Use Other Serious 9/12/2007 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 7/16/2009 74 Female 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/1/2009 Male 184 lb 8/17/2009 Physician United States
Primary
Concomitant
Pneumonia 10/23/2008 Female 175 lb 9/19/2009 United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 9/16/2009 United Kingdom
Primary
Concomitant
Sudden Death Death 8/12/2009 55 Male 202 lb 9/21/2009 Physician United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Required Intervention 11/8/2008 72 Female 234 lb 11/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2009 61 Female 236 lb 10/2/2009 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 9/1/2009 61 Female 133 lb 9/30/2009 Consumer United States
Primary
Concomitant

Drug Data