Bumetanide combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nausea Other Serious 40 Male 218 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/1/2005 78 Male 1/19/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 1/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/19/2006 70 Male 166 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Unresponsive To Verbal Stimuli Death 4/28/2006 Female 105 lb 5/9/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 5/12/2006 Physician Netherlands
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 3/10/2006 89 Male Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Unresponsive To Verbal Stimuli Life Threatening 4/28/2006 Female 105 lb 6/20/2006 Pharmacist United States
Primary
Concomitant
Pneumonitis Life Threatening 3/2/2006 56 Male 6/26/2006 Physician Netherlands
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/22/2005 57 Female 143 lb 6/23/2006 Belgium
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 7/14/2006 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 7/31/2006 United Kingdom
Primary
Secondary
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 8/4/2006 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 91 Female 8/3/2006 United Kingdom
Primary
Secondary
Therapeutic Response Decreased 12/19/2005 Male 168 lb 8/9/2006 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 8/4/2006 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/5/2006 91 Female 8/21/2006 Denmark
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious 5/1/2005 78 Male 9/5/2006 United Kingdom
Primary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Cardiac Failure Congestive Other Serious 75 Female 133 lb 10/10/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 5/3/2006 91 Female 10/9/2006 Germany
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 10/17/2006 United Kingdom
Primary
Secondary
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 10/20/2006 Consumer United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 1/1/2006 91 Female 10/12/2006 United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 10/12/2006 United Kingdom
Primary
Secondary
Renal Failure Hospitalization 5/3/2006 91 Female 10/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 10/26/2006 United Kingdom
Primary
Secondary
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/2/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vasoconstriction Other Serious 54 Male 150 lb 11/6/2006 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 11/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 6/15/2006 50 Female 12/21/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 8/10/2006 80 Male 12/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dry Throat 1/1/2006 47 Female 130 lb 10/24/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/9/2007 80 Male 234 lb 1/12/2007 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 12/20/2006 72 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 9/29/2006 75 Male 216 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Cardiac Failure Other Serious 54 Male 150 lb 3/12/2007 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 9/28/2004 53 Male 183 lb 11/17/2005 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/11/2007 80 Male 219 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Rash Required Intervention 12/14/2006 54 Male 12/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 59 Male 4/6/2007 Pharmacist Ireland
Primary
Concomitant
Angioedema Life Threatening 3/6/2007 69 Male 152 lb 4/16/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 59 Male 205 lb 4/19/2007 Other Health Professional Ireland
Primary
Concomitant
Pemphigoid Other Serious 70 Male 4/19/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Other Serious 59 Male 5/25/2007 Ireland
Primary
Concomitant
Drug Interaction Other Serious 59 Male 6/19/2007 Ireland
Primary
Concomitant
Interacting
Psychomotor Hyperactivity 87 Female 118 lb 6/22/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 59 Male 205 lb 6/25/2007 Ireland
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/13/2007 64 Female 6/28/2007 Physician
Primary
Concomitant
Soft Tissue Infection Other Serious 1/17/2007 Male 271 lb 7/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/1997 Female 7/20/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/3/2006 91 Female 7/17/2007 United Kingdom
Primary
Secondary
Renal Failure Hospitalization 5/3/2006 91 Female 8/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 205 lb 8/31/2007 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 5/16/1997 69 Female 8/30/2007 Physician Netherlands
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/10/2007 51 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 50 Male 209 lb 11/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 66 Female 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 11/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 6/1/2006 Female 12/7/2007 Belgium
Primary
Concomitant
Insomnia 8/1/2007 76 Male 201 lb 11/19/2007 United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 66 Female 1/18/2008 Physician
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tinnitus 68 Female 2/13/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/1/2007 Female 209 lb 2/15/2008 Physician
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 2/13/2008 United Kingdom
Primary
Secondary
Concomitant
Urticaria Required Intervention 2/1/2008 62 Male 262 lb 2/29/2008 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Other Serious 68 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 80 Male 4/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/18/2008 Female 5/12/2008 Pharmacist United States
Primary
Concomitant
Oral Intake Reduced Hospitalization Male 5/13/2008 United States
Primary
Concomitant
Death Death Male 5/20/2008 Pharmacist United States
Primary
Concomitant
Syncope Life Threatening 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 143 lb 5/16/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 3/1/2008 Male 6/2/2008 Physician United States
Primary
Concomitant
Syncope Other Serious 83 Female 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Syncope Other Serious 83 Female 6/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 1/1/2004 Female 6/13/2008 France
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization 5/1/2008 Male 287 lb 6/13/2008 Physician United States
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 83 Female 143 lb 6/10/2008
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 73 Male 8/5/2008 Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/5/2008 98 Female 90 lb 7/29/2008 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hallucination 4/8/2008 66 Female 158 lb 8/15/2008 Other Health Professional United States
Primary
Concomitant
Stomach Discomfort 7/23/2008 Female 228 lb 8/29/2008 United States
Primary
Concomitant
Insomnia 8/1/2007 76 Male 210 lb 7/23/2008 United States
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/25/2008
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 62 Female 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 8/13/2008 78 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/5/2006 91 Female 10/22/2008 Denmark
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 5/3/2006 91 Female 10/22/2008 Denmark
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Pruritus Male 11/26/2008 United States
Primary
Concomitant
Weight Decreased 7/1/2008 86 Male 11/28/2008 United Kingdom
Primary
Concomitant
Renal Failure Other Serious 87 Female 12/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Hospitalization 5/1/2008 59 Male 288 lb 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/18/2008 Male 1/26/2009 Physician France
Primary
Concomitant
Interacting
Visual Acuity Reduced Other Serious Female 1/27/2009 Consumer Switzerland
Primary
Concomitant
Abdominal Neoplasm Hospitalization Male 230 lb 3/5/2009 Consumer United States
Primary
Concomitant
Scab Hospitalization 66 Male 2/28/2009 United States
Primary
Concomitant
Death Death Female 3/30/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 4/3/2009 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 4/10/2009 Physician Netherlands
Primary
Concomitant
Interacting
Renal Failure Hospitalization 66 Male 4/7/2009 United States
Primary
Concomitant
Rash Pruritic Other Serious 3/1/2009 62 Female 154 lb 4/17/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 Female 154 lb 4/27/2009 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 143 lb 5/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/1/2009 70 Male 125 lb 4/29/2009 Other Health Professional Belgium
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 66 Male 5/1/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/1/2009 Female 154 lb 5/13/2009 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 143 lb 5/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 5/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 143 lb 5/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 143 lb 5/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 143 lb 5/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Product Quality Issue 57 Male 5/26/2009 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/14/2009 75 5/18/2009 United Kingdom
Primary
Concomitant

Drug Data