Bumetanide combined with Carvedilol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nausea Other Serious 40 Male 218 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 12/30/2005 58 Male 180 lb 1/19/2006 United States
Primary
Concomitant
Epistaxis Hospitalization 1/30/2006 87 Male 3/1/2006 Pharmacist Ireland
Primary
Concomitant
International Normalised Ratio Abnormal Other Serious 2/1/2006 62 Female 3/13/2006 Pharmacist Netherlands
Primary
Concomitant
Interacting
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Unevaluable Event Death 66 Male 134 lb 5/23/2006 Physician United Kingdom
Primary
Concomitant
Pneumonitis Life Threatening 3/2/2006 56 Male 6/26/2006 Physician Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Chest Pain Hospitalization 49 Male 7/11/2006 Consumer Ireland
Primary
Secondary
Concomitant
Chest Pain Hospitalization 49 Male 7/19/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 49 Male 7/21/2006 Consumer Ireland
Primary
Secondary
Concomitant
Chest Pain Hospitalization 6/9/2006 49 Male 7/24/2006 Pharmacist Ireland
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 4/1/2006 66 Male 134 lb 8/2/2006 Physician United Kingdom
Primary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 9/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 10/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 75 Female 133 lb 10/10/2006 Pharmacist United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 207 lb 10/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 12/12/2006 Female 223 lb 12/19/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 12/20/2006 72 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 1/14/2007 70 Female 4/2/2007 Norway
Primary
Concomitant
Oedema Peripheral Hospitalization 4/10/2007 Male 154 lb 7/3/2007 Physician
Primary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 Female 10/11/2007 Belgium
Primary
Concomitant
Dyspnoea Hospitalization 7/10/2007 51 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 3/1/2007 Female 10/18/2007 Belgium
Primary
Concomitant
Urinary Tract Infection Bacterial Other Serious 3/1/2007 Female 11/16/2007 Belgium
Primary
Concomitant
Myoclonus Required Intervention 1/29/2006 65 Male 12/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 1/29/2006 65 Male 12/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Staphylococcal Infection Other Serious 3/1/2007 Female 12/21/2007 Belgium
Primary
Concomitant
Myoclonus Hospitalization 1/1/2006 65 Male 1/30/2008 Pharmacist United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 75 Female 1/23/2008 Physician Netherlands
Primary
Concomitant
Weight Increased Other Serious 2/1/2006 63 Female 2/4/2008 Consumer United States
Primary
Secondary
Concomitant
Urticaria Required Intervention 2/1/2008 62 Male 262 lb 2/29/2008 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 68 Male 5/13/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 5/5/2008 98 Female 90 lb 5/23/2008 Pharmacist United States
Primary
Concomitant
Drug Effect Decreased Hospitalization 8/5/2007 88 Female 5/7/2008 Physician United States
Primary
Concomitant
Sluggishness Other Serious 5/1/2008 Female 5/1/2008 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 7/17/2008 78 Female 139 lb 8/15/2008 Consumer Belgium
Primary
Concomitant
Stomach Discomfort 7/23/2008 Female 228 lb 8/29/2008 United States
Primary
Concomitant
Injection Site Pain 1/1/2007 Male 230 lb 9/12/2008 United States
Primary
Concomitant
Wheezing Other Serious 2/20/2008 10 Male 9/17/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/8/2007 Female 112 lb 11/3/2008 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 76 Male 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Pruritus Male 11/26/2008 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 2/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 10/21/2006 71 Female 2/13/2009 Physician United States
Primary
Secondary
Concomitant
Death Death Female 199 lb 3/17/2009 Physician United States
Primary
Concomitant
Rash Vesicular Hospitalization 3/3/2009 74 Male 3/19/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death Female 199 lb 3/24/2009 Physician United States
Primary
Concomitant
Rash Vesicular Hospitalization 3/3/2009 74 Male 297 lb 4/14/2009 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 12/4/2008 69 Male 194 lb 12/5/2008 Pharmacist United States
Primary
Concomitant
Presyncope Hospitalization 3/31/2009 Male 6/2/2009 Physician Netherlands
Primary
Secondary
Weight Decreased Other Serious 1/1/2005 Female 219 lb 6/29/2009 Consumer United States
Primary
Concomitant
Mydriasis Death 1/9/2009 85 Female 7/24/2009 Germany
Primary
Secondary
Concomitant
Sepsis Death 91 Female 8/3/2009 Consumer United Kingdom
Primary
Concomitant
Sepsis Death 91 Female 8/6/2009 United Kingdom
Primary
Concomitant
Rash Vesicular Hospitalization 3/3/2009 74 Male 297 lb 8/13/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Death 72 Female 8/10/2009 United States
Primary
Concomitant
Urosepsis Death 91 Female 8/19/2009 Consumer United Kingdom
Primary
Concomitant
Muscle Spasms 1/1/2000 Male 8/22/2009 United States
Primary
Concomitant
Unevaluable Event Death Female 8/20/2009 United States
Primary
Concomitant
Urosepsis Death 91 Female 8/20/2009 United Kingdom
Primary
Concomitant
Urosepsis Death 91 Female 9/4/2009 Physician United Kingdom
Primary
Concomitant
Skin Discolouration Other Serious 8/6/2009 Male 9/14/2009 Consumer Netherlands
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 9/16/2009 United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Required Intervention 11/8/2008 72 Female 234 lb 11/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2009 61 Female 236 lb 10/2/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Female 10/18/2009 United States
Primary
Concomitant
Lethargy Hospitalization 11/21/2008 55 Female 229 lb 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Social Problem Hospitalization Female 11/3/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Death 72 Female 11/18/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 72 Female 12/2/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2006 76 Female 198 lb 12/11/2009 United States
Primary
Concomitant
Hyponatraemia Other Serious 1/1/2009 64 Male 268 lb 12/16/2009 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 72 Female 12/10/2009 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/10/2009 50 Male 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2010 Female 3/2/2010 Consumer United Kingdom
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Cardiac Arrest Death 2/25/2009 Female 3/12/2010 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Hepatic Cirrhosis Other Serious Male 4/13/2010 Pharmacist Netherlands
Primary
Concomitant
Rash Hospitalization 1/1/2010 Female 4/21/2010 Consumer United Kingdom
Primary
Concomitant
Off Label Use Hospitalization Male 187 lb 5/5/2010 Pharmacist Netherlands
Primary
Concomitant
Skin Cancer Other Serious 4/18/2010 87 Female 170 lb 5/6/2010 United States
Primary
Concomitant
Death Death 83 Male 5/24/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 5/18/2010 Lawyer United States
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 4/18/2010 87 Female 170 lb 5/24/2010 United States
Primary
Concomitant
Urinary Incontinence Other Serious 10/1/2009 80 Female 135 lb 6/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 3/1/2008 60 Female 6/23/2010 Other Health Professional United States
Primary
Concomitant
Pancreatic Carcinoma Metastatic Death 83 Male 190 lb 7/16/2010 Consumer United States
Primary
Concomitant
Intestinal Ischaemia Hospitalization 7/15/2009 62 Female 161 lb 7/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Burning Sensation Other Serious 4/1/2010 87 Female 170 lb 8/4/2010 Consumer United States
Primary
Concomitant
Intestinal Ischaemia Hospitalization 7/15/2009 62 Female 161 lb 8/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Other Serious 12/15/2009 65 Male 316 lb 1/25/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 9/10/2010 United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/1/2008 67 Male 10/12/2010 Consumer
Primary
Concomitant
Dyspnoea Hospitalization 12/1/2008 67 Male 10/18/2010 Consumer
Primary
Concomitant
Sputum Discoloured Hospitalization 9/30/2010 80 Male 10/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 12/1/2008 67 Male 10/25/2010 Consumer
Primary
Concomitant
Cardiac Valve Disease Hospitalization 90 Male 11/1/2010 Consumer United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 9/30/2010 80 Male 10/20/2010 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 52 Male 11/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/1/2008 67 Male 12/9/2010 Consumer
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Delirium Hospitalization 10/8/2010 77 Male 11/30/2010 Pharmacist United States
Primary
Concomitant
Cardio-respiratory Arrest Death 78 Female 1/5/2011 United States
Primary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Arthropathy Other Serious 1/1/2006 76 Female 198 lb 1/28/2011 Lawyer United States
Primary
Concomitant
Nasopharyngitis 9/1/2010 75 Female 1/30/2011 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Male 3/14/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2003 56 Male 4/15/2011 Consumer United States
Primary
Secondary
Concomitant
Melaena Hospitalization 1/24/2011 60 Male 80 lb 4/28/2011 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Pain Death 8/29/2001 70 Male 190 lb 5/3/2011 Lawyer United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/9/2011 Consumer United States
Primary
Concomitant
Intentional Drug Misuse Male 197 lb 6/15/2011 Physician United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/16/2011 Consumer United States
Primary
Concomitant
Generalised Oedema Other Serious 3/1/2011 77 Female 6/23/2011 Pharmacist United States
Primary
Concomitant
Visual Impairment Other Serious Male 245 lb 6/24/2011 Consumer United Kingdom
Primary
Concomitant
Syncope Other Serious 5/21/2011 91 Male 218 lb 6/29/2011 Physician Ireland
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 5/21/2011 75 Male 258 lb 7/19/2011 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/14/2011 77 Male 176 lb 7/19/2011 Physician Netherlands
Primary
Concomitant
Syncope Hospitalization 4/11/2011 81 Male 161 lb 7/20/2011 Physician Netherlands
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/14/2011 73 Male 8/5/2011 Consumer United States
Primary
Concomitant
Flushing 1/1/2010 67 Male 313 lb 8/5/2011 Consumer United States
Primary
Concomitant
Syncope Hospitalization 4/5/2011 81 Male 161 lb 8/12/2011 Physician Netherlands
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/14/2011 77 Male 176 lb 8/16/2011 Physician Netherlands
Primary
Concomitant
Myoclonus Hospitalization 5/8/2011 69 Female 8/23/2011 Physician Netherlands
Primary
Secondary
Concomitant
Erythema Death 5/1/2011 70 Female 339 lb 8/31/2011 Physician United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 5/21/2011 75 Male 258 lb 9/13/2011 United States
Primary
Concomitant
Hyperkalaemia Death 5/1/2011 70 Female 339 lb 9/19/2011 Physician United States
Primary
Concomitant
Rash Hospitalization 5/13/2011 58 Female 255 lb 9/23/2011 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/14/2011 77 Male 176 lb 9/30/2011 Physician Netherlands
Primary
Concomitant
Syncope Hospitalization 4/5/2011 81 Male 161 lb 10/6/2011 Physician Netherlands
Primary
Concomitant
Syncope Other Serious 7/21/2010 68 Male 182 lb 10/13/2011 Physician Netherlands
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 5/13/2011 58 Female 255 lb 10/18/2011 Consumer United States
Primary
Concomitant
Haematoma Hospitalization 3/3/2010 67 Female 11/11/2011 Physician United States
Primary
Concomitant

Drug Data