Brotizolam combined with Magnesium Oxide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Other Serious 2/8/2004 Female 3/21/2006 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 12/15/2005 Female 97 lb 3/21/2006 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 12/15/2005 Female 97 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 12/14/2005 Female 97 lb 5/12/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Death 9/29/2005 Male 121 lb 6/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 12/4/2003 Female 108 lb 6/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Retinopathy Other Serious 2/8/2004 Female 1/3/2007 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 5/2/2006 Male 115 lb 1/5/2007 Japan
Primary
Concomitant
Tachycardia Other Serious 12/1/2002 18 Male 104 lb 1/10/2007 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/14/2007 Male 170 lb 2/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 2/23/2007 Other Health Professional Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 3/7/2007 Other Health Professional Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 5/3/2007 Other Health Professional Japan
Primary
Concomitant
Hyperglycaemia Life Threatening 2/12/2007 Male 170 lb 5/16/2007 Other Health Professional Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 6/7/2007 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 7/9/2007 Female 104 lb 8/2/2007 Physician Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 8/1/2006 65 Male 8/8/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/8/2007 76 Male 8/6/2007 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 8/21/2007 Other Health Professional Japan
Primary
Concomitant
Liver Disorder Hospitalization 9/27/2006 Male 8/22/2007 Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/1/2004 Male 9/5/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 9/7/2007 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/9/2007 Female 104 lb 9/7/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 10/1/2007 United Kingdom
Primary
Secondary
Concomitant
Ileus Paralytic Other Serious 90 Female 11/16/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Paranoia Other Serious 8/1/2007 57 Female 12/6/2007 Other Health Professional Japan
Primary
Concomitant
Paranoia Other Serious 8/1/2007 57 Female 12/14/2007 Other Health Professional Japan
Primary
Concomitant
Purpura Hospitalization 11/11/2007 Female 113 lb 1/7/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Water Intoxication Hospitalization 4/24/2007 Female 108 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 2/12/2008 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 146 lb 2/12/2008 United Kingdom
Primary
Secondary
Concomitant
Purpura Hospitalization 11/11/2007 Female 113 lb 2/14/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Water Intoxication Other Serious 1/28/2008 68 Male 2/15/2008 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 146 lb 2/18/2008 United Kingdom
Primary
Secondary
Concomitant
Water Intoxication Other Serious 1/28/2008 68 Male 3/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 12/4/2003 Female 108 lb 3/21/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 146 lb 4/8/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/26/2008 70 Female 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/23/2008 Female 174 lb 4/29/2008 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 5/29/2008 Other Health Professional Japan
Primary
Concomitant
Femoral Neck Fracture Hospitalization Male 8/8/2008 Japan
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 8/11/2008 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 3/20/2006 Male 115 lb 9/3/2008 Japan
Primary
Concomitant
Pneumonia Bacterial Death 7/25/2007 91 Male 9/11/2008 Japan
Primary
Concomitant
Somnolence Other Serious 7/18/2008 76 Female 9/12/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/18/2008 Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 7/18/2008 Female 82 lb 10/27/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/27/2008 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/29/2008 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 11/5/2008 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/17/2008 Male 104 lb 11/26/2008 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/17/2008 Male 104 lb 12/1/2008 Japan
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 94 Female 12/1/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 7/17/2007 80 Male 12/5/2008 Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 12/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 1/1/2007 79 Male 12/16/2008 Japan
Primary
Concomitant
Lung Abscess Hospitalization 1/1/2007 79 Male 12/17/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 11/17/2008 12/22/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/21/2008 Male 12/24/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 11/17/2008 1/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/17/2008 2/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileus Other Serious 9/9/2008 59 Female 86 lb 3/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileus Other Serious 9/9/2008 59 Female 86 lb 3/30/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sedation Other Serious 7/29/2008 86 Female 3/30/2009 Germany
Primary
Concomitant
Irritability Life Threatening 5/8/2008 4/29/2009 Physician Japan
Primary
Concomitant
Pancreatic Carcinoma Life Threatening 5/8/2009 Male 5/22/2009 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 12/10/2008 Male 5/28/2009 Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 12/10/2008 Male 6/5/2009 Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 12/10/2008 Male 6/12/2009 Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 12/10/2008 Male 6/22/2009 Japan
Primary
Secondary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 66 Male 6/25/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 5/25/2009 59 Male 6/30/2009 Other Health Professional France
Primary
Secondary
Concomitant
Ileus Other Serious 9/9/2008 59 Female 86 lb 7/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 6/10/2009 Female 7/14/2009 Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 66 Male 7/23/2009 Physician Japan
Primary
Concomitant
Ileus Other Serious 9/9/2008 59 Female 86 lb 7/24/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 5/8/2009 Male 152 lb 8/21/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 4/11/2009 Female 99 lb 8/21/2009 Japan
Primary
Concomitant
Pancreatic Carcinoma Hospitalization 5/8/2009 Male 152 lb 9/1/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 4/11/2009 Female 99 lb 9/3/2009 Japan
Primary
Concomitant
Urinary Retention Other Serious 12/10/2008 Male 9/10/2009 Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 4/11/2009 Female 99 lb 9/15/2009 Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 6/19/2008 Male 9/16/2009 Physician Japan
Primary
Concomitant
Obesity Other Serious 6/30/2009 Male 9/21/2009 Other Health Professional Japan
Primary
Concomitant
Ileus Other Serious 9/9/2008 59 Female 86 lb 10/8/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileus Other Serious 9/9/2008 59 Female 86 lb 10/19/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/20/2009 Female 157 lb 10/30/2009 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 6/30/2009 Male 10/27/2009 Japan
Primary
Concomitant
Tendon Rupture Hospitalization 2/24/2009 Female 110 lb 11/2/2009 Japan
Primary
Concomitant
Skin Ulcer Disability 8/31/2009 Female 11/4/2009 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 6/30/2009 Male 11/5/2009 Physician Japan
Primary
Concomitant
Skin Ulcer 7/31/2009 Female 11/16/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Death 6/10/2009 Female 11/30/2009 Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/20/2009 Female 157 lb 12/10/2009 Physician Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/8/2008 61 Female 90 lb 12/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/17/2008 78 Male 104 lb 12/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteitis Other Serious 9/12/2008 63 Female 101 lb 12/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 6/11/2009 Female 12/21/2009 Japan
Primary
Concomitant
Somnolence Other Serious 5/8/2009 Male 152 lb 12/22/2009 Physician Japan
Primary
Concomitant
Somnolence Other Serious 5/8/2009 Male 152 lb 12/26/2009 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Osteitis Other Serious 4/26/2008 63 Female 101 lb 12/30/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Water Intoxication Other Serious 36 Male 12/31/2009 Japan
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 89 lb 1/15/2010 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/8/2008 61 Female 90 lb 1/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Water Intoxication Other Serious 36 Male 1/19/2010 Japan
Primary
Concomitant
Mania Hospitalization 3/1/2009 Male 170 lb 2/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/17/2009 67 Male 2/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/20/2009 Female 157 lb 2/19/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/17/2009 67 Male 2/5/2010 Physician Japan
Primary
Concomitant
Water Intoxication Other Serious 36 Male 2/22/2010 Japan
Primary
Concomitant
Neuropathy Peripheral Other Serious 2/23/2009 67 Male 170 lb 2/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 2/3/2009 Male 3/16/2010 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 2/17/2010 52 Male 3/26/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 5/15/2009 67 Female 89 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 3/16/2010 73 Male 4/5/2010 Japan
Primary
Concomitant
Somnolence Other Serious 5/8/2009 67 Male 152 lb 4/20/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 2/17/2010 52 Male 4/13/2010 Physician Japan
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 6/19/2008 65 Male 4/8/2010 Physician Japan
Primary
Concomitant
Urinary Incontinence Other Serious 3/16/2010 73 Male 4/20/2010 Japan
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 5/15/2009 67 Female 89 lb 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 52 Male 5/13/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 3/16/2010 73 Male 5/12/2010 Japan
Primary
Concomitant
Somnolence Other Serious 52 Male 6/1/2010 Japan
Primary
Secondary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 5/15/2009 67 Female 89 lb 6/4/2010 Physician Japan
Primary
Secondary
Concomitant
Ileus Paralytic Hospitalization 3/5/2010 66 Female 87 lb 6/11/2010 Physician Japan
Primary
Concomitant
Somnolence Other Serious 52 Male 6/4/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 4/11/2009 67 Female 99 lb 6/15/2010 Other Health Professional Japan
Primary
Concomitant
Ileus Paralytic Hospitalization 3/5/2010 66 Female 87 lb 6/25/2010 Physician Japan
Primary
Concomitant
Ileus Paralytic Hospitalization 2/22/2010 66 Female 87 lb 6/30/2010 Physician Japan
Primary
Concomitant
Restlessness Other Serious 7/15/2010 89 Male 8/9/2010 Japan
Primary
Concomitant
Somnolence Other Serious 7/10/2010 48 Female 8/4/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/16/2010 74 Female 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Restlessness Other Serious 7/15/2010 89 Male 8/13/2010 Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 7/29/2010 44 Male 117 lb 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/16/2010 74 Female 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 7/29/2010 44 Male 117 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 2/4/2010 70 Female 9/1/2010 Japan
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 7/29/2010 44 Male 117 lb 9/13/2010 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 12/22/2009 47 Female 9/7/2010 Physician Japan
Primary
Secondary
Concomitant
Eosinophilia Hospitalization 8/31/2010 69 Female 9/17/2010 Physician Japan
Primary
Secondary
Jaundice Cholestatic Hospitalization 7/29/2010 44 Male 117 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
Eosinophilia Hospitalization 8/31/2010 69 Female 9/24/2010 Physician Japan
Primary
Secondary
Spinal Compression Fracture Hospitalization 2/4/2010 70 Female 9/21/2010 Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 2/4/2010 70 Female 10/11/2010 Japan
Primary
Secondary
Concomitant

Drug Data