Brotizolam combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyelonephritis Acute Hospitalization 10/1/2005 Female 130 lb 2/3/2006 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 12/15/2005 Female 97 lb 3/21/2006 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 12/15/2005 Female 97 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 12/14/2005 Female 97 lb 5/12/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 12/4/2003 Female 108 lb 6/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 4/4/2006 Female 121 lb 1/3/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/22/2006 Female 134 lb 1/19/2007 Japan
Primary
Concomitant
Sepsis Hospitalization 12/22/2006 Female 134 lb 1/30/2007 Japan
Primary
Concomitant
Sepsis Hospitalization 12/22/2006 Female 134 lb 1/30/2007 Japan
Primary
Concomitant
Pneumonia Aspiration Life Threatening 3/12/2007 80 Male 4/6/2007 Physician Japan
Primary
Concomitant
Hemianopia Disability 3/14/2007 64 Female 5/18/2007 Physician Japan
Primary
Concomitant
Hemianopia Disability 3/10/2007 64 Female 110 lb 6/1/2007 Physician Japan
Primary
Concomitant
Cerebral Infarction Disability 3/6/2007 64 Female 110 lb 6/14/2007 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 6/21/2007 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 8/6/2007 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 6/21/2007 Male 8/27/2007 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/27/2007 Female 88 lb 10/3/2007 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 12/22/2006 Female 134 lb 10/9/2007 Japan
Primary
Concomitant
Sepsis Hospitalization 12/22/2006 Female 134 lb 11/2/2007 Japan
Primary
Concomitant
Sepsis Other Serious 5/25/2007 76 Female 11/5/2007 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 12/22/2006 Female 134 lb 11/8/2007 Japan
Primary
Concomitant
Rash Other Serious 12/4/2003 Female 108 lb 3/21/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Condition Aggravated Life Threatening 11/1/2007 Female 4/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 5/25/2007 76 Female 5/5/2008 Physician Japan
Primary
Concomitant
Sepsis Other Serious 5/25/2007 76 Female 5/19/2008 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/9/2008 Male 9/5/2008 Japan
Primary
Secondary
Concomitant
Interacting
Serotonin Syndrome Other Serious 8/28/2008 Female 10/1/2008 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/3/2009 25 Male 3/4/2009 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 5/1/2009 Female 139 lb 7/9/2009 Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/1/2009 Female 139 lb 7/15/2009 Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/1/2009 Female 139 lb 7/20/2009 Japan
Primary
Secondary
Concomitant
Myositis Hospitalization 5/4/2009 58 8/7/2009 Physician Japan
Primary
Concomitant
Myositis Hospitalization 5/4/2009 58 8/17/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 5/1/2009 Female 139 lb 9/18/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/18/2009 Female 79 lb 9/25/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/18/2009 Female 79 lb 11/4/2009 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 2/3/2009 Male 3/16/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 5/15/2009 67 Female 89 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 7/29/2010 44 Male 117 lb 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 7/29/2010 44 Male 117 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 7/29/2010 44 Male 117 lb 9/13/2010 Physician Japan
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 7/29/2010 44 Male 117 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
Thymol Turbidity Test Increased Other Serious 6/7/2010 33 Male 9/29/2010 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 4/28/2010 19 Female 115 lb 11/8/2010 Physician Japan
Primary
Concomitant
Pneumothorax Hospitalization 11/1/2009 69 Male 11/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thymol Turbidity Test Increased Other Serious 6/7/2010 33 Male 11/10/2010 Physician Japan
Primary
Concomitant
Fall Other Serious 4/5/2010 79 Male 104 lb 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 7/29/2010 44 Male 117 lb 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Tongue Coated Hospitalization 75 Female 123 lb 12/15/2010 Other Health Professional Japan
Primary
Concomitant
Hyperlipidaemia Other Serious 6/7/2010 33 Male 12/16/2010 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2009 53 Female 159 lb 1/10/2011 Physician Japan
Primary
Concomitant
Lymphocyte Stimulation Test Positive Hospitalization 11/1/2009 69 Male 1/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 7/29/2010 44 Male 117 lb 2/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemolysis Hospitalization 12/29/2010 46 Female 3/3/2011 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Hospitalization 3/31/2011 68 Female 5/6/2011 Physician Japan
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 3/31/2011 68 Female 5/6/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 2/23/2011 62 Male 5/26/2011 Physician Japan
Primary
Concomitant
Malaise Other Serious 4/15/2011 79 Male 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 6/1/2010 69 Male 137 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 6/1/2010 69 Male 137 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 12/20/2010 60 Female 6/10/2011 Physician Japan
Primary
Concomitant
Loss Of Consciousness Death 4/15/2011 79 Male 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 8/31/2010 56 Female 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 5/12/2011 61 Female 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 58 Male 6/28/2011 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 6/15/2011 79 Female 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 6/15/2011 79 Female 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Accidental Overdose Hospitalization 5/12/2011 61 Female 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Life Threatening 5/12/2011 61 Female 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 6/15/2011 79 Female 7/7/2011 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/15/2011 79 Female 108 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/15/2011 79 Female 108 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Body Temperature Increased Hospitalization 8/28/2010 71 Male 141 lb 7/18/2011 Other Health Professional Japan
Primary
Concomitant
Deafness Hospitalization 8/1/2007 86 Female 86 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/16/2009 59 Female 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/16/2009 59 Female 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Cryptococcosis Other Serious 9/10/2008 58 Female 134 lb 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 8/3/2010 76 Male 152 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Thoracic Outlet Syndrome Hospitalization 12/18/2010 42 Female 8/12/2011 Physician Japan
Primary
Concomitant
Enteritis Infectious Hospitalization 12/18/2010 42 Female 8/18/2011 Physician Japan
Primary
Concomitant
Infection Hospitalization 8/28/2010 71 Male 141 lb 8/24/2011 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/13/2010 65 Female 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/18/2011 86 Male 9/8/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 2/4/2011 60 Male 148 lb 9/9/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/18/2011 86 Male 9/16/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/26/2011 73 Male 9/21/2011 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 8/26/2011 73 Male 10/19/2011 Physician Japan
Primary
Concomitant
Thoracic Outlet Syndrome Hospitalization 12/18/2010 42 Female 10/20/2011 Physician Japan
Primary
Concomitant
Convulsion Other Serious 10/16/2011 78 Male 11/23/2011 Consumer Japan
Primary
Secondary
Concomitant
Infection Disability 4/28/2010 19 Female 115 lb 11/29/2011 Physician Japan
Primary
Concomitant
Dry Skin Death 8/3/2010 76 Male 152 lb 11/30/2011 Physician Japan
Primary
Secondary
Concomitant
Bedridden Other Serious 10/4/2011 49 Male 12/12/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 10/6/2011 59 Female 157 lb 12/14/2011 Physician Japan
Primary
Concomitant
Intracardiac Thrombus Other Serious 11/17/2010 60 Male 110 lb 12/19/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 9/23/2011 66 Female 139 lb 12/21/2011 Physician Japan
Primary
Concomitant
Enteritis Infectious Hospitalization 12/18/2010 42 Female 12/22/2011 Physician Japan
Primary
Concomitant
Convulsion Other Serious 10/16/2011 78 Male 12/26/2011 Consumer Japan
Primary
Secondary
Concomitant
Migraine Hospitalization 12/18/2010 42 Female 12/27/2011 Physician Japan
Primary
Concomitant
Bedridden Hospitalization 10/12/2011 49 Male 1/4/2012 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 10/12/2011 49 Male 1/5/2012 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Disability 10/6/2011 66 Male 82 lb 1/5/2012 Physician Japan
Primary
Concomitant
Insomnia Hospitalization 9/21/2011 70 Female 1/13/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 1/5/2012 64 Female 82 lb 1/25/2012 Consumer Japan
Primary
Secondary
Concomitant
Neurogenic Bladder Other Serious 80 Female 113 lb 2/3/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Ileitis Hospitalization 1/1/2012 64 Female 82 lb 2/13/2012 Consumer Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Hospitalization 9/20/2011 70 Female 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Depression Other Serious 2/13/2012 58 Male 2/15/2012 Physician Japan
Primary
Concomitant
Dystonia Hospitalization 2/4/2012 85 Female 2/19/2012 Consumer Japan
Primary
Concomitant
Herpes Zoster Other Serious 1/25/2012 64 Female 2/28/2012 Consumer Germany
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 10/6/2011 59 Female 157 lb 3/2/2012 Japan
Primary
Concomitant
Neutropenia Hospitalization 10/6/2011 59 Female 157 lb 3/6/2012 Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 1/5/2012 64 Female 82 lb 3/9/2012 Consumer Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 8/26/2011 73 Male 3/13/2012 Physician Japan
Primary
Secondary
Concomitant
Depression Death 11/6/2009 46 Male 132 lb 3/14/2012 Physician Japan
Primary
Concomitant
Drug Level Increased Other Serious 1/25/2012 64 Female 3/21/2012 Consumer Germany
Primary
Concomitant
Cystitis Haemorrhagic Disability 4/28/2010 19 Female 115 lb 3/21/2012 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 8/19/2009 65 Female 121 lb 3/23/2012 Physician Japan
Primary
Concomitant
Perineal Pain 2/15/2012 68 Male 3/26/2012 Pharmacist Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/26/2011 73 Male 3/25/2012 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 8/19/2009 65 Female 121 lb 3/26/2012 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 12/1/2008 83 Male 125 lb 3/27/2012 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/23/2011 62 Male 3/28/2012 Physician Japan
Primary
Concomitant
Staphylococcus Test Positive Hospitalization 12/1/2008 83 Male 125 lb 4/5/2012 Physician Japan
Primary
Secondary
Concomitant
Acidosis Other Serious 1/25/2012 64 Female 4/12/2012 Consumer Germany
Primary
Concomitant
Fatigue Hospitalization 3/29/2012 72 Female 124 lb 4/16/2012 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/14/2012 70 Female 76 lb 4/26/2012 Other Health Professional Japan
Primary
Concomitant
Fatigue Hospitalization 3/29/2012 72 Female 124 lb 5/7/2012 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/14/2012 70 Female 76 lb 5/8/2012 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 8/13/2010 65 Female 5/25/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/8/2012 67 Female 95 lb 5/25/2012 Physician Japan
Primary
Concomitant
Fatigue Hospitalization 3/29/2012 72 Female 124 lb 6/15/2012 Physician Japan
Primary
Secondary
Concomitant
Heart Rate Decreased Death 3/19/2011 73 Male 170 lb 7/2/2012 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/28/2012 64 Female 79 lb 7/9/2012 Physician Japan
Primary
Concomitant
Pneumonia Death 7/3/2012 87 Male 117 lb 7/16/2012 Other Health Professional Japan
Primary
Concomitant
Rash Erythematous Hospitalization 8/11/2009 83 Male 125 lb 7/23/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 8/11/2009 83 Male 125 lb 7/24/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 6/28/2012 64 Female 79 lb 8/14/2012 Physician Japan
Primary
Concomitant
Rash Hospitalization 11/15/2011 67 Male 139 lb 8/20/2012 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/23/2011 67 Female 139 lb 12/21/2012 Physician Jp
Primary
Concomitant
Dyspnoea Death 1/31/2012 58 Male 144 lb 11/20/2012 Physician Country Not Specified
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/23/2012 57 Female 119 lb 11/5/2012 Physician Jp
Primary
Secondary
Concomitant
Eosinophilic Pneumonia Hospitalization 7/29/2012 71 Male 106 lb 10/1/2012 Physician Jp
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/14/2012 63 Male 110 lb 10/9/2012 Physician Jp
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 10/16/2012 71 Male 146 lb 12/17/2012 Physician Jp
Primary
Concomitant
Fall Other Serious 3/9/2013 80 Female 93 lb 4/29/2013 Pharmacist Jp
Primary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 7/1/2011 35 Male 139 lb 5/23/2013 Physician Jp
Primary
Concomitant
Eye Movement Disorder Hospitalization 4/14/2013 92 Female 5/24/2013 Consumer Jp
Primary
Concomitant

Drug Data