Blinded Bevacizumab combined with Capecitabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Hospitalization 1/30/2006 59 Female 125 lb 2/28/2006 Physician United States
Primary
Secondary
Pyrexia Hospitalization 10/11/2005 62 Female 126 lb 3/3/2006 Physician Spain
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 10/21/2004 64 Female 249 lb 3/27/2006 Physician Canada
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 10/21/2004 64 Female 249 lb 4/19/2006 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/9/2004 73 Female 97 lb 7/5/2006 Physician Norway
Primary
Secondary
Sinus Tachycardia Hospitalization 7/9/2006 61 Female 164 lb 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/9/2006 61 Female 164 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 7/31/2006 Female 9/6/2006 Physician United States
Primary
Secondary
Diverticulitis Hospitalization 11/3/2006 57 Female 162 lb 11/17/2006 Physician United States
Primary
Secondary
Gastritis Erosive Hospitalization 10/17/2006 57 Female 139 lb 11/24/2006 Physician United States
Primary
Secondary
Diverticulitis Hospitalization 11/3/2006 57 Female 162 lb 11/30/2006 Physician United States
Primary
Secondary
Gastritis Erosive Hospitalization 10/17/2006 57 Female 139 lb 12/14/2006 Physician United States
Primary
Secondary
Gastrointestinal Toxicity Hospitalization 9/7/2006 55 Female 187 lb 12/21/2006 Physician United States
Primary
Secondary
Diverticulitis Hospitalization 11/3/2006 57 Female 162 lb 12/22/2006 Physician United States
Primary
Secondary
Head Injury Hospitalization 12/12/2006 79 Female 116 lb 1/11/2007 Physician United States
Primary
Secondary
Hyperglycaemia Hospitalization 11/24/2006 77 Female 1/12/2007 Physician United States
Primary
Secondary
Pleural Effusion Hospitalization 1/10/2007 60 Female 167 lb 1/29/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 2/2/2007 71 Female 2/19/2007 Physician United States
Primary
Secondary
Proteinuria Hospitalization 2/2/2007 71 Female 2/20/2007 Physician United States
Primary
Secondary
Head Injury Hospitalization 12/12/2006 79 Female 116 lb 2/20/2007 Physician United States
Primary
Secondary
Mental Status Changes Hospitalization 2/10/2007 82 Female 110 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 2/10/2007 82 Female 110 lb 4/23/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Disability 3/26/2007 62 Female 140 lb 4/30/2007 Physician United States
Primary
Secondary
Diaphragmatic Hernia Hospitalization 1/10/2007 60 Female 167 lb 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Tumour Necrosis Hospitalization 4/13/2007 47 Female 111 lb 6/27/2007 Physician United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 8/2/2007 65 Female 236 lb 8/17/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/21/2007 63 Female 9/4/2007 Other Health Professional United States
Primary
Secondary
Muscle Twitching Hospitalization 7/24/2007 59 Female 254 lb 9/4/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/29/2007 62 Female 163 lb 9/10/2007 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 8/21/2007 63 Female 9/10/2007 Other Health Professional United States
Primary
Secondary
Cerebral Thrombosis Death 9/8/2007 36 Female 143 lb 9/24/2007 Physician United States
Primary
Secondary
Mental Status Changes Hospitalization 8/2/2007 65 Female 236 lb 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/21/2007 Female 10/1/2007 Consumer Australia
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/29/2007 62 Female 163 lb 10/5/2007 Physician United States
Primary
Secondary
Cerebral Ischaemia Hospitalization 9/8/2007 56 Female 143 lb 10/23/2007 Physician United States
Primary
Secondary
Mental Status Changes Hospitalization 8/2/2007 65 Female 236 lb 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/21/2007 Female 10/24/2007 Consumer Australia
Primary
Secondary
Concomitant
Ureteric Obstruction Hospitalization 10/25/2007 42 Female 227 lb 11/6/2007 Physician United States
Primary
Secondary
Osteomyelitis Hospitalization 10/5/2007 70 Female 118 lb 11/21/2007 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 9/5/2007 58 Female 12/4/2007 Physician United States
Primary
Secondary
Respiratory Failure Life Threatening 10/16/2007 63 Female 154 lb 12/7/2007 Physician United States
Primary
Secondary
Ureteric Obstruction Hospitalization 10/25/2007 42 Female 227 lb 12/10/2007 Consumer United States
Primary
Secondary
Hypoglycaemia Hospitalization 9/5/2007 58 Female 12/21/2007 Other Health Professional United States
Primary
Secondary
Cardiogenic Shock Life Threatening 12/13/2007 56 Female 121 lb 1/9/2008 Physician United States
Primary
Secondary
Cardiogenic Shock Hospitalization 12/13/2007 56 Female 121 lb 1/15/2008 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Death 12/27/2007 54 Female 123 lb 1/17/2008 Physician United States
Primary
Secondary
Herpes Oesophagitis Hospitalization 6/4/2007 74 Female 161 lb 1/22/2008 Physician United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/24/2008 Female 141 lb 2/5/2008 Physician United States
Primary
Secondary
Concomitant
Herpes Oesophagitis Hospitalization 6/4/2007 74 Female 161 lb 2/14/2008 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 2/2/2008 79 Female 117 lb 2/15/2008 Physician United States
Primary
Secondary
Hypoglycaemia Hospitalization 9/5/2007 58 Female 2/18/2008 Other Health Professional United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 7/16/2007 78 Female 123 lb 2/18/2008 Other Health Professional United States
Primary
Secondary
Tumour Necrosis Hospitalization 1/28/2008 46 Male 172 lb 2/25/2008 Physician Japan
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/24/2008 Female 141 lb 2/25/2008 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 2/2/2008 79 Female 117 lb 3/13/2008 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 1/28/2008 79 Female 117 lb 3/14/2008 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 1/28/2008 79 Female 117 lb 3/18/2008 Physician United States
Primary
Secondary
Tumour Necrosis Hospitalization 1/28/2008 46 Male 172 lb 3/21/2008 Physician Japan
Primary
Secondary
Concomitant
Arteriospasm Coronary Hospitalization 2/8/2008 54 Female 163 lb 3/28/2008 Physician Australia
Primary
Secondary
Concomitant
Tumour Ulceration Hospitalization 1/28/2008 46 Male 172 lb 3/31/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/22/2008 72 Male 176 lb 4/2/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/22/2008 Male 176 lb 4/11/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/29/2008 Male 132 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Blood Urea Increased Hospitalization 3/11/2008 Male 176 lb 4/18/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 3/29/2008 Male 132 lb 4/22/2008 Physician Japan
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 3/19/2008 Male 137 lb 4/22/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Oliguria Hospitalization 3/22/2008 Male 176 lb 4/28/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 3/29/2008 Male 132 lb 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/11/2008 Male 176 lb 5/2/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/24/2007 Female 123 lb 5/2/2008 Physician United States
Primary
Secondary
Pneumonia Aspiration Life Threatening 3/29/2008 Male 132 lb 7/1/2008 Physician Japan
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 6/23/2008 Male 7/2/2008 Other Health Professional Japan
Primary
Secondary
Gastric Perforation Hospitalization 6/27/2008 Male 111 lb 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 3/29/2008 Male 132 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Other Serious 6/23/2008 Male 7/17/2008 Other Health Professional Japan
Primary
Secondary
Pneumonia Hospitalization 4/16/2008 Male 106 lb 8/7/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 4/27/2008 Female 8/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/4/2008 Male 133 lb 8/25/2008 Physician Peru
Primary
Secondary
Jaundice Cholestatic Hospitalization 4/27/2008 Female 8/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Life Threatening 4/5/2007 Female 115 lb 8/27/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/1/2005 Male 159 lb 9/2/2008 Physician Brazil
Primary
Secondary
Concomitant
Wound Infection Other Serious 6/23/2008 Male 117 lb 9/4/2008 Other Health Professional Japan
Primary
Secondary
Gastric Perforation Hospitalization 6/27/2008 Male 111 lb 9/4/2008 Physician Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 9/2/2008 Female 126 lb 9/11/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Malaise Death 8/29/2008 Male 111 lb 9/16/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 9/5/2008 Male 115 lb 9/16/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/23/2008 Female 99 lb 9/22/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Jejunitis Hospitalization 7/17/2007 Female 146 lb 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 9/2/2008 Female 126 lb 9/29/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Hospitalization 9/7/2008 Female 132 lb 9/29/2008 Physician Germany
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 9/5/2008 Male 115 lb 9/30/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Febrile Neutropenia Death 8/29/2008 Male 111 lb 9/30/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/1/2005 Male 159 lb 9/30/2008 Physician Brazil
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 6/27/2008 Male 111 lb 9/30/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Hospitalization 9/7/2008 Female 132 lb 10/1/2008 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 10/3/2008 Male 121 lb 10/17/2008 Physician France
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Hospitalization 9/7/2008 Female 132 lb 10/17/2008 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 10/17/2006 Female 139 lb 10/23/2008 Physician United States
Primary
Secondary
Large Intestinal Ulcer Other Serious 8/25/2008 Female 106 lb 10/23/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Wound Infection Hospitalization 7/31/2006 Female 10/29/2008 Physician United States
Primary
Secondary
Laboratory Test Abnormal Hospitalization 10/16/2008 Female 97 lb 11/3/2008 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 3/11/2008 Male 176 lb 11/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 9/17/2008 Male 89 lb 11/4/2008 Physician Japan
Primary
Secondary
Weight Decreased Hospitalization 10/3/2008 Male 121 lb 11/4/2008 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/16/2008 Male 106 lb 11/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/20/2008 Male 11/4/2008 Physician United Kingdom
Primary
Secondary
Laboratory Test Abnormal Life Threatening 10/16/2008 Female 97 lb 11/5/2008 Physician Brazil
Primary
Secondary
Concomitant
Appendicitis Hospitalization 10/23/2008 Male 11/18/2008 Physician Peru
Primary
Secondary
Laboratory Test Abnormal Life Threatening 10/16/2008 Female 97 lb 11/21/2008 Physician Brazil
Primary
Secondary
Concomitant
Febrile Neutropenia Death 8/29/2008 Male 102 lb 11/26/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Vomiting Death 11/17/2008 Female 104 lb 12/2/2008 Physician Peru
Primary
Secondary
Laboratory Test Abnormal Life Threatening 10/16/2008 Female 97 lb 12/2/2008 Physician Brazil
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 11/25/2008 Male 145 lb 12/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Blood Urea Increased Hospitalization 11/25/2008 Male 145 lb 12/9/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Blood Urea Increased Hospitalization 11/25/2008 Male 145 lb 12/18/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Febrile Neutropenia Death 8/29/2008 Male 102 lb 12/18/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/23/2008 Female 99 lb 12/26/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Ileus Hospitalization 6/27/2008 Male 111 lb 12/26/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/11/2008 Male 176 lb 12/26/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 8/3/2008 Male 102 lb 12/29/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 6/27/2008 Male 111 lb 1/12/2009 Physician Japan
Primary
Secondary
Concomitant
Laboratory Test Abnormal Life Threatening 10/16/2008 Female 97 lb 1/22/2009 Physician Brazil
Primary
Secondary
Concomitant
Metastases To Meninges Hospitalization 1/14/2009 Male 1/22/2009 Physician Japan
Primary
Secondary
Dyspnoea Hospitalization 11/16/2008 Female 147 lb 1/23/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Other Serious 9/7/2008 Female 132 lb 2/4/2009 Physician Germany
Primary
Secondary
Concomitant
Metastases To Meninges Hospitalization 1/14/2009 Male 2/10/2009 Physician Japan
Primary
Secondary
Retinopathy Hospitalization 1/13/2009 Male 168 lb 2/13/2009 Physician Russian Federation
Primary
Secondary
Interstitial Lung Disease Hospitalization 11/19/2008 Female 207 lb 2/18/2009 Physician United States
Primary
Secondary
Hepatic Artery Thrombosis Other Serious 9/7/2008 Female 132 lb 2/19/2009 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/12/2009 Female 2/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/23/2008 Female 99 lb 2/25/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/23/2008 Female 99 lb 3/3/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/23/2008 Female 99 lb 3/4/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Metastases To Meninges Hospitalization 1/14/2009 Male 3/5/2009 Physician Japan
Primary
Secondary
Hypokalaemia Life Threatening 8/3/2008 Male 102 lb 3/9/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Metastases To Meninges Hospitalization 1/14/2009 Male 154 lb 3/18/2009 Physician Japan
Primary
Secondary
Dyspnoea Hospitalization 11/16/2008 Female 147 lb 3/19/2009 Physician Germany
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 8/3/2008 Male 102 lb 3/30/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 1/14/2009 Male 154 lb 3/30/2009 Physician Japan
Primary
Secondary
Appendicitis Perforated Hospitalization 10/23/2008 Male 137 lb 4/1/2009 Physician Peru
Primary
Secondary
Wound Infection Other Serious 6/23/2008 Male 112 lb 4/6/2009 Other Health Professional Japan
Primary
Secondary
Intestinal Obstruction Hospitalization 3/28/2009 Male 4/13/2009 Physician Japan
Primary
Secondary
Intestinal Obstruction Hospitalization 3/28/2009 Male 4/15/2009 Consumer United Kingdom
Primary
Secondary
Pulmonary Haemorrhage Life Threatening 12/16/2008 Male 209 lb 4/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 12/16/2008 Male 209 lb 5/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 3/28/2009 Male 5/11/2009 Physician Japan
Primary
Secondary
Upper Gastrointestinal Haemorrhage Hospitalization 8/23/2008 Female 99 lb 5/21/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 9/17/2008 Male 89 lb 5/26/2009 Physician Japan
Primary
Secondary
Pneumonia Aspiration Hospitalization 9/17/2008 Male 89 lb 5/26/2009 Physician Japan
Primary
Secondary
Pneumonia Hospitalization 4/16/2008 Male 106 lb 5/29/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant

Drug Data