Blinded Bevacizumab combined with Blinded Placebo

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Chest Pain Hospitalization 5/12/2007 Female 5/17/2007 Physician United Kingdom
Primary
Secondary
Chest Pain Hospitalization 5/12/2007 Female 5/21/2007 Physician United Kingdom
Primary
Secondary
Chest Pain Hospitalization 5/12/2007 Female 5/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 5/3/2007 Female 153 lb 5/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 5/3/2007 Female 153 lb 6/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/26/2007 Female 145 lb 8/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization Female 123 lb 9/20/2007 Consumer United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 8/21/2007 Female 10/1/2007 Consumer Australia
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/29/2007 62 Female 163 lb 10/5/2007 Physician United States
Primary
Secondary
Left Ventricular Dysfunction Hospitalization 7/5/2007 Female 137 lb 10/12/2007 Physician Norway
Primary
Secondary
Pneumonia Hospitalization 8/19/2007 Female 123 lb 10/15/2007 Consumer United Kingdom
Primary
Secondary
Cerebral Ischaemia Hospitalization 9/8/2007 56 Female 143 lb 10/23/2007 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 8/21/2007 Female 10/24/2007 Consumer Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/11/2007 Female 160 lb 10/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/11/2007 Female 160 lb 11/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 11/2/2007 Female 157 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 7/5/2007 Female 137 lb 11/16/2007 Physician Norway
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 10/3/2007 Male 11/16/2007 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 10/26/2007 Male 201 lb 11/16/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 10/5/2007 70 Female 118 lb 11/21/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 201 lb 11/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 10/16/2007 63 Female 154 lb 12/7/2007 Physician United States
Primary
Secondary
Mouth Ulceration Hospitalization 11/22/2007 Male 169 lb 12/10/2007 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/22/2007 Male 169 lb 12/18/2007 Consumer United Kingdom
Primary
Secondary
Hypoglycaemia Hospitalization 9/5/2007 58 Female 12/21/2007 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 1/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/7/2008 Female 154 lb 1/17/2008 Physician Malaysia
Primary
Secondary
Diarrhoea Death 12/27/2007 54 Female 123 lb 1/17/2008 Physician United States
Primary
Secondary
Pulmonary Oedema Hospitalization 12/31/2007 Female 139 lb 1/24/2008 Physician United States
Primary
Secondary
Convulsion Hospitalization 1/24/2008 Female 141 lb 2/5/2008 Physician United States
Primary
Secondary
Concomitant
Herpes Oesophagitis Hospitalization 6/4/2007 74 Female 161 lb 2/14/2008 Physician United States
Primary
Secondary
Febrile Neutropenia Life Threatening 11/1/2007 Male 146 lb 2/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 9/5/2007 58 Female 2/18/2008 Other Health Professional United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 7/16/2007 78 Female 123 lb 2/18/2008 Other Health Professional United States
Primary
Secondary
Confusional State Hospitalization 2/8/2008 Male 2/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 2/8/2008 Male 2/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/24/2008 Female 141 lb 2/25/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/7/2008 Female 154 lb 2/26/2008 Physician Malaysia
Primary
Secondary
Febrile Neutropenia Hospitalization 2/11/2008 Female 2/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/15/2008 Male 3/4/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Death 2/3/2008 Female 149 lb 3/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 2/8/2008 Male 3/18/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2008 Male 146 lb 3/25/2008 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/8/2007 Female 120 lb 3/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/28/2007 Female 120 lb 3/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 3/15/2008 Female 132 lb 3/28/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 4/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Fungal Oesophagitis Hospitalization 2/22/2008 Female 126 lb 4/7/2008 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 11/8/2007 Female 120 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/28/2007 Female 120 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/21/2007 Female 265 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/19/2007 Female 122 lb 4/14/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Life Threatening 3/15/2008 Female 132 lb 4/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Head Injury Hospitalization 3/13/2008 Female 104 lb 4/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/10/2008 Male 181 lb 4/17/2008 Other Health Professional United States
Primary
Secondary
Anaemia Hospitalization 11/2/2007 Female 157 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/8/2007 Female 120 lb 4/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 11/1/2007 Male 146 lb 4/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 2/1/2008 Male 140 lb 5/1/2008 Physician Hong Kong
Primary
Secondary
Deep Vein Thrombosis Other Serious 4/10/2008 Male 268 lb 5/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 4/17/2008 Female 143 lb 5/2/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 12/24/2007 Female 123 lb 5/2/2008 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 4/24/2008 Female 122 lb 5/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 3/1/2008 Male 5/9/2008 Physician United Kingdom
Primary
Secondary
Septic Shock Life Threatening 3/15/2008 Female 132 lb 5/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 4/4/2008 Male 268 lb 5/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Death 2/3/2008 Female 149 lb 5/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/5/2008 Male 5/13/2008 Other Health Professional United States
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 2/13/2008 Male 5/13/2008 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 4/10/2008 Male 181 lb 5/14/2008 Other Health Professional United States
Primary
Secondary
Dehydration Hospitalization 4/25/2008 Female 110 lb 5/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/31/2007 Female 139 lb 5/21/2008 Physician United States
Primary
Secondary
Malignant Pleural Effusion Hospitalization 5/13/2008 Female 165 lb 5/23/2008 Physician Australia
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/25/2008 Female 110 lb 5/23/2008 Physician United Kingdom
Primary
Secondary
Chest Pain Hospitalization 5/15/2008 Female 174 lb 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 4/17/2008 Female 143 lb 5/27/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 3/13/2008 Male 146 lb 5/30/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 4/24/2008 Female 122 lb 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 5/21/2008 Female 122 lb 6/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/8/2008 65 Female 6/6/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/31/2007 Female 139 lb 6/18/2008 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 3/13/2008 Male 146 lb 6/18/2008 Consumer United Kingdom
Primary
Secondary
Acute Pulmonary Oedema Hospitalization 2/3/2008 Female 149 lb 6/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/25/2008 Female 110 lb 6/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/8/2007 Female 120 lb 7/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 7/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 4/4/2008 Male 268 lb 7/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 5/21/2008 Female 122 lb 7/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/2/2008 Male 7/15/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 3/13/2008 Male 146 lb 7/16/2008 Consumer United Kingdom
Primary
Secondary
Confusional State Hospitalization 2/8/2008 Male 7/16/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 5/15/2008 Female 174 lb 7/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/4/2008 Male 7/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/15/2008 Female 132 lb 7/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/11/2008 Male 139 lb 7/23/2008 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 7/9/2008 Male 199 lb 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/12/2008 Female 7/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/19/2008 Male 7/30/2008 Physician Austria
Primary
Secondary
Ascites Hospitalization 5/30/2008 Male 7/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/9/2008 Male 199 lb 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/2/2008 Male 8/1/2008 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/11/2008 Female 8/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 8/1/2008 Male 8/8/2008 Physician United States
Primary
Secondary
Jaundice Cholestatic Hospitalization 4/27/2008 Female 8/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/12/2008 Female 8/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Hospitalization 2/3/2008 Female 149 lb 8/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/15/2008 Female 132 lb 8/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/28/2007 Female 120 lb 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/2/2008 Male 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/2/2008 Male 8/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 4/27/2008 Female 8/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 8/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Life Threatening 4/5/2007 Female 115 lb 8/27/2008 Physician United States
Primary
Secondary
Concomitant
Bronchopleural Fistula Hospitalization 5/13/2008 Female 165 lb 8/29/2008 Physician Australia
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 9/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/18/2008 Male 9/4/2008 Physician United Kingdom
Primary
Secondary
Sinus Tachycardia Hospitalization 8/14/2008 Female 9/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/25/2008 Female 9/11/2008 Physician United Kingdom
Primary
Secondary
General Physical Health Deterioration Hospitalization 8/4/2008 Male 9/11/2008 Physician United Kingdom
Primary
Secondary
Septic Shock Other Serious 8/25/2008 Female 9/15/2008 Physician United Kingdom
Primary
Secondary
Cavernous Sinus Thrombosis Hospitalization 8/25/2008 Male 9/15/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 9/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/11/2008 Male 139 lb 9/16/2008 Physician United States
Primary
Secondary
General Physical Health Deterioration Hospitalization 8/4/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Small Intestinal Obstruction Hospitalization 6/23/2008 Female 9/17/2008 Other Health Professional United States
Primary
Secondary
Thrombosis Hospitalization 9/3/2008 Male 9/17/2008 Consumer United Kingdom
Primary
Secondary
Septic Shock Other Serious 8/25/2008 Female 9/18/2008 Physician United Kingdom
Primary
Secondary
Syncope Hospitalization 7/28/2008 Female 9/19/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 7/12/2008 Female 9/23/2008 Consumer Spain
Primary
Secondary
Concomitant
Jejunitis Hospitalization 7/17/2007 Female 146 lb 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/1/2008 Male 9/24/2008 Physician United States
Primary
Secondary
Respiratory Syncytial Virus Infection Hospitalization 8/2/2008 Male 9/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/14/2008 Male 9/25/2008 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/18/2008 Male 9/25/2008 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 7/2/2008 Female 9/30/2008 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 6/1/2007 9/30/2008 Physician Singapore
Primary
Secondary
Septic Shock Death 9/19/2008 Male 10/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/14/2008 Female 10/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/14/2008 Male 10/9/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 9/25/2008 Female 10/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/1/2008 Male 10/10/2008 Physician United States
Primary
Secondary
Stomatitis Hospitalization 9/14/2008 Female 10/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/14/2008 Male 10/17/2008 Physician United Kingdom
Primary
Secondary
Fat Necrosis Other Serious 6/18/2008 54 Female 10/22/2008 Physician United States
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 3/15/2008 Female 108 lb 10/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 10/17/2006 Female 139 lb 10/23/2008 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 7/12/2008 Female 10/23/2008 Consumer Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/25/2008 Female 10/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastritis Erosive Life Threatening 10/9/2008 Male 149 lb 10/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data