Bisoprolol combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Aortic Thrombosis Hospitalization 1/1/2005 65 Male 5/3/2006 Pharmacist Germany
Primary
Concomitant
Cholelithiasis Hospitalization 1/14/2007 80 Male 2/19/2007 United Kingdom
Primary
Concomitant
Death Hospitalization 7/13/2006 Male 159 lb 5/9/2007 United Kingdom
Primary
Concomitant
Hypertension Hospitalization 5/1/2007 84 Female 7/12/2007 Other Health Professional France
Primary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 255 lb 7/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 5/1/2007 84 Female 7/18/2007 Other Health Professional France
Primary
Concomitant
Torsade De Pointes Life Threatening 65 Female 2/1/2008 Other Health Professional France
Primary
Concomitant
Ileal Ulcer Other Serious 10/1/2008 Male 172 lb 10/10/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/6/2008 Female 2/13/2009 Consumer United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 10/15/2008 64 Male 209 lb 3/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Hospitalization 1/17/2009 79 Female 5/1/2009
Primary
Secondary
Concomitant
Syncope Death 1/6/2009 79 Female 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Death 79 Female 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/9/2009 61 Female 141 lb 6/3/2009 Physician Germany
Primary
Secondary
Concomitant
Pleuropericarditis Hospitalization 5/9/2009 65 Female 6/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 1/1/2009 51 Female 188 lb 7/1/2009 Physician Germany
Primary
Concomitant
Interacting
Pain Other Serious 1/1/2007 68 Male 7/28/2009 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 8/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/9/2009 Other Health Professional Denmark
Primary
Concomitant
Hypertension Life Threatening 9/18/2009 62 Female 212 lb 10/5/2009 Pharmacist Canada
Primary
Concomitant
Syncope Death 1/6/2009 79 Female 10/23/2009 United Kingdom
Primary
Concomitant
Rash Pustular Hospitalization 3/11/2008 57 Female 11/6/2009 Physician Germany
Primary
Concomitant
Rash Pustular Hospitalization 3/11/2008 57 Female 11/18/2009 Physician Germany
Primary
Concomitant
Liver Disorder Hospitalization 11/20/2009 74 Female 1/21/2010 Germany
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 2/3/2006 58 Male 2/1/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Hyponatraemia Hospitalization 2/3/2006 58 Male 2/1/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Death Hospitalization Female 3/5/2010 Physician Canada
Primary
Concomitant
Pain Disability 3/7/2010 69 Female 3/23/2010 Consumer Canada
Primary
Concomitant
Renal Failure Hospitalization 3/9/2009 61 Female 141 lb 6/3/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/18/2010 70 Male 148 lb 6/3/2010 Physician Netherlands
Primary
Secondary
Concomitant
Major Depression Disability 11/1/2009 75 Male 137 lb 8/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neck Pain Hospitalization 5/2/2010 80 Female 8/5/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Major Depression Disability 11/1/2009 75 Female 137 lb 8/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Flow Decreased Disability 11/1/2009 75 Male 137 lb 8/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 7/1/2009 83 Female 99 lb 8/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Other Serious 8/21/2010 59 Male 9/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 7/31/2010 52 Male 10/4/2010 Other Health Professional France
Primary
Secondary
Concomitant
Walking Disability Other Serious 8/6/2010 82 Female 10/21/2010 Other Health Professional France
Primary
Secondary
Concomitant
Sudden Death Death 7/31/2010 52 Male 10/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Catheter Site Necrosis Other Serious 8/21/2010 59 Male 10/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/1/2010 82 Female 11/4/2010 Other Health Professional France
Primary
Secondary
Interacting
Pseudomonas Test Positive Other Serious 8/21/2010 59 Male 11/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 79 187 lb 11/22/2010 Other Health Professional Germany
Primary
Concomitant
Suicide Attempt Other Serious 79 Male 187 lb 11/30/2010 Other Health Professional Germany
Primary
Concomitant
Lipoma Other Serious 1/1/2010 67 Female 147 lb 1/26/2011 Physician Canada
Primary
Concomitant
Myositis Other Serious 1/6/2009 79 Female 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chromaturia 12/1/2010 60 Male 168 lb 4/13/2011 Physician United Kingdom
Primary
Concomitant
Off Label Use Other Serious 3/3/2011 92 Female 126 lb 4/20/2011 Consumer France
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 84 Female 8/29/2011 Other Health Professional Finland
Primary
Concomitant
Femur Fracture Hospitalization 84 Female 8/30/2011 Other Health Professional Finland
Primary
Concomitant
Rash Death 57 Female 126 lb 9/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/10/2011 57 Female 126 lb 9/29/2011 Consumer United Kingdom
Primary
Concomitant
Neutropenic Sepsis Death 8/10/2011 57 Female 9/30/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
International Normalised Ratio Increased Death 57 Female 126 lb 10/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drooling Hospitalization 5/6/2011 54 Female 10/17/2011 Other Health Professional Ireland
Primary
Concomitant
Myocardial Infarction Death Female 10/19/2011 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 8/1/2010 88 Female 11/1/2011 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 11/19/2011 48 Male 176 lb 2/6/2012 Other Health Professional Canada
Primary
Concomitant
Chest Pain Hospitalization 11/11/2011 58 Female 5/14/2012 Physician United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 1/28/2012 49 Male 5/21/2012 Other Health Professional France
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 5/20/2012 87 Female 161 lb 6/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 3/2/2012 82 Male 179 lb 6/23/2012 Physician Sweden
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 1/1/2012 82 Female 131 lb 8/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Hospitalization 82 Female 131 lb 8/15/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Death 2/17/2012 82 Male 179 lb 1/4/2013 Physician Se
Primary
Secondary
Concomitant
Myalgia Hospitalization 2/2012 60 Male 10/19/2012 Other Health Professional De
Primary
Concomitant
Muscular Sarcoidosis Hospitalization 3/15/2012 60 Male 11/11/2013 Other Health Professional De
Primary
Concomitant
Renal Impairment Hospitalization 1/4/2012 83 Male 4/22/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Gastric Haemorrhage Life Threatening 59 Female 10/31/2013 Pharmacist Gb
Primary
Concomitant
Skeletal Injury Other Serious 8/21/2012 41 Female 219 lb 9/11/2012 Other Health Professional Ca
Primary
Concomitant
Withdrawal Syndrome Other Serious 2001 Female 171 lb 10/1/2012 Consumer Gb
Primary
Concomitant
Renal Failure Hospitalization 7/24/2012 58 Female 193 lb 10/28/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 9/18/2012 NotSpecified 4/11/2013 Physician Fr
Primary
Secondary
Concomitant
Mania Disability 8/24/2012 70 Female 210 lb 10/16/2012 Physician Gb
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 9/18/2012 69 Male 126 lb 8/1/2013 Physician Fr
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/15/2011 54 Male 219 lb 11/2/2012 Other Health Professional Gb
Primary
Concomitant
Myocardial Infarction Death 87 Male 11/7/2012 Other Health Professional De
Primary
Concomitant
Interacting
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Pulmonary Congestion Hospitalization 10/12/2012 70 Male 213 lb 11/15/2012 Physician Gb
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/15/2012 72 Female 106 lb 4/11/2013 De
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Disability 10/20/2012 70 Female 128 lb 11/27/2012 Physician Gb
Primary
Concomitant
Ventricular Hypokinesia Death 87 Male 1/15/2013 Other Health Professional De
Primary
Secondary
Concomitant
Myocardial Infarction Death 87 Male 12/17/2012 Physician De
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/21/2011 90 Female 12/19/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Renal Impairment Hospitalization 9/21/2011 90 Female 12/20/2012 Pharmacist Gb
Primary
Concomitant
Interacting
Off Label Use Other Serious 2012 60 Female 201 lb 12/21/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Myocardial Infarction Death 87 Male 12/21/2012 Physician De
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/21/2011 90 Female 12/28/2012 Pharmacist Gb
Primary
Concomitant
Interacting
Renal Impairment Hospitalization 9/21/2011 90 Female 12/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/21/2011 90 Female 12/21/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Myalgia Hospitalization 8/26/2012 73 Male 196 lb 1/11/2013 Physician De
Primary
Concomitant
Dystonia Other Serious 12/5/2012 76 Female 1/3/2013 Gb
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/28/2011 76 Female 2/7/2013 Pharmacist Gb
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/28/2011 76 Female 2/5/2013 Pharmacist Gb
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/28/2011 76 Female 2/4/2013 Pharmacist Gb
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/28/2011 76 Female 1/30/2013 Pharmacist Gb
Primary
Concomitant
Blood Glucose Increased Other Serious 50 Male 273 lb 2/1/2013 Physician Ca
Primary
Concomitant
Weight Decreased Hospitalization 2012 83 Female 160 lb 1/25/2013 Other Health Professional Se
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/14/2013 68 Male 137 lb 3/13/2013 Physician Be
Primary
Secondary
Concomitant
Incorrect Dose Administered Death 1/5/2013 64 Female 309 lb 1/22/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 76 Female 1/25/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Acute Disability 1/1/2009 64 Female 252 lb 3/11/2013 Physician Gb
Primary
Concomitant
Ventricular Tachycardia Hospitalization 76 Female 2/5/2013 Gb
Primary
Secondary
Concomitant
Renal Failure Acute Disability 1/1/2009 64 Female 252 lb 3/14/2013 Physician Gb
Primary
Concomitant
Vasculitic Rash Other Serious 2/9/2013 56 Male 141 lb 3/20/2013 Other Health Professional Gb
Primary
Concomitant
Palpitations Hospitalization 2/20/2013 45 Female 249 lb 3/20/2013 Pharmacist Gb
Primary
Concomitant
Myocardial Infarction Hospitalization 10/15/2012 57 Male 5/23/2013 Physician Gb
Primary
Concomitant
Pneumonia Other Serious 1/2012 66 Male 234 lb 4/5/2013 Other Health Professional Ca
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2011 NotSpecified 4/25/2013 Other Health Professional De
Primary
Concomitant
Salivary Hypersecretion Life Threatening 1/7/2013 51 Male 7/25/2013 Physician De
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/1/2011 73 Female 198 lb 4/29/2013 Consumer De
Primary
Concomitant
Gastroenteritis Hospitalization 11/20/2012 52 Male 123 lb 5/2/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Acute Life Threatening 3/1/2011 73 Female 198 lb 5/3/2013 Physician De
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 3/18/2013 73 Female 128 lb 8/27/2013 Physician Fr
Primary
Secondary
Concomitant
Pyrexia Other Serious 87 Male 5/18/2013 Other Health Professional Country Not Specified
Primary
Secondary
Serotonin Syndrome Other Serious 5/2013 75 Male 5/28/2013 Pharmacist De
Primary
Concomitant
Hypertension Hospitalization 12/12/2012 65 Male 179 lb 5/29/2013 Physician Gb
Primary
Concomitant
Movement Disorder Disability 1/2013 79 NotSpecified 5/29/2013 Other Health Professional Gb
Primary
Concomitant
Vision Blurred Other Serious 3/9/2011 Female 5/22/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Movement Disorder Disability 1/2013 79 NotSpecified 6/3/2013 Physician Gb
Primary
Concomitant
Movement Disorder Disability 1/2013 79 NotSpecified 6/6/2013 Physician Gb
Primary
Concomitant
Prescribed Overdose Disability 1/2013 79 NotSpecified 6/7/2013 Other Health Professional Dk
Primary
Concomitant
Subileus Other Serious 8/10/2008 84 Male 154 lb 11/15/2013 Physician De
Primary
Concomitant
Movement Disorder Disability 1/2013 79 NotSpecified 6/7/2013 Physician Gb
Primary
Concomitant
Tendonitis Hospitalization 5/3/2013 Female 112 lb 11/1/2013 Other Health Professional Gb
Primary
Concomitant
Tendonitis Hospitalization 5/2/2013 Female 112 lb 11/6/2013 Physician Gb
Primary
Concomitant
Tendonitis Disability 5/3/2013 Female 112 lb 6/5/2013 Physician Gb
Primary
Concomitant
Tendonitis Hospitalization 5/2/2013 Female 112 lb 11/12/2013 Consumer Gb
Primary
Concomitant
Tendonitis Hospitalization 5/2/2013 Female 112 lb 11/12/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Acute Hospitalization 3/19/2013 71 Male 229 lb 6/21/2013 Other Health Professional Fr
Primary
Concomitant
Thrombosis Death 6/6/2013 62 Female 7/4/2013 Other Health Professional Fr
Primary
Concomitant
Tinnitus Hospitalization 48 Male 7/8/2013 Consumer De
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/2/2013 87 Male 7/10/2013 Physician Se
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/18/2013 78 Female 123 lb 7/9/2013 Consumer Gb
Primary
Concomitant
Hepatic Infection Hospitalization 7/6/2013 72 Male 216 lb 9/10/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/25/2013 78 Male 132 lb 8/5/2013 Physician Gb
Primary
Concomitant
Oxygen Saturation Decreased Disability 2013 71 Male 207 lb 7/27/2013 Physician Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/2013 61 Male 12/30/2013 Other Health Professional Ie
Primary
Concomitant
Nausea Disability 7/26/2013 90 Female 8/20/2013 Physician Gb
Primary
Concomitant
Hallucination Hospitalization 2/20/2010 89 Male 8/24/2013 Other Health Professional Gb
Primary
Concomitant
Hallucination Hospitalization 2/20/2010 89 Male 8/27/2013 Pharmacist Gb
Primary
Concomitant
Hallucination Hospitalization 2/20/2010 89 Male 8/30/2013 Pharmacist Gb
Primary
Concomitant
Hallucination Hospitalization 2/20/2010 89 Male 9/4/2013 Other Health Professional Gb
Primary
Concomitant
Sepsis Hospitalization 3/4/2013 80 Female 126 lb 10/8/2013 Physician De
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Hospitalization 2/15/2013 79 Male 161 lb 7/30/2013 Physician Ca
Primary
Concomitant
Acute Hepatic Failure Death 8/15/2013 67 Male 216 lb 9/20/2013 Other Health Professional Gb
Primary
Concomitant
Acute Hepatic Failure Death 8/15/2013 67 Male 216 lb 9/23/2013 Physician Gb
Primary
Concomitant
Wheezing Hospitalization 9/9/2013 72 Male 10/4/2013 Physician Gb
Primary
Concomitant
Wheezing Hospitalization 9/9/2013 72 Male 10/10/2013 Consumer Gb
Primary
Concomitant

Drug Data