Bisoprolol combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Death 12/1/2005 60 Male 187 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 7/15/2005 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/7/2005 73 Male 150 lb 4/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 6/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 8/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 12/11/2007 94 Female 99 lb 2/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 6/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Bronchitis Hospitalization 1/19/2009 Physician Sweden
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Pruritus Hospitalization 7/28/2008 75 Female 144 lb 1/29/2009 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 7/26/2008 70 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 8/7/2008 52 Male 123 lb 2/27/2009 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Peripheral Embolism Hospitalization 12/18/2008 52 Male 123 lb 2/27/2009 Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Bronchitis Hospitalization 12/1/2008 4/24/2009 Physician Sweden
Primary
Secondary
Concomitant
Gout Other Serious 3/21/2009 4/28/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Syncope Death 1/6/2009 79 Female 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palpitations Hospitalization 5/26/2009 69 6/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 7/26/2008 70 Male 6/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Cancer Other Serious 3/1/2008 Male 203 lb 7/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 79 Female 7/6/2009 Consumer United Kingdom
Primary
Concomitant
Gout Other Serious 3/21/2009 73 7/21/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 6/9/2009 68 Male 229 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 2/8/2009 75 Female 132 lb 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 5/1/2008 Male 8/12/2009 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/10/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/13/2009 Physician United States
Primary
Concomitant
Multiple Myeloma Death 3/17/2009 Male 8/24/2009 Pharmacist United States
Primary
Concomitant
Laboratory Test Abnormal Required Intervention 6/28/2009 66 Male 172 lb 7/9/2009 United States
Primary
Concomitant
Sciatica Other Serious 9/1/2009 Female 10/9/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 10/21/2009 Physician Sweden
Primary
Secondary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/6/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 Male 161 lb 12/11/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 9/8/2009 71 Male 198 lb 1/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 1/5/2010 Denmark
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 Male 161 lb 2/16/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/29/2008 55 Female 223 lb 3/10/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 3/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 3/25/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 4/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/23/2010 69 4/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 3/23/2010 69 4/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2006 64 Female 183 lb 5/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Bone Pain Hospitalization 4/18/2008 64 Male 158 lb 5/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2006 64 Female 183 lb 5/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2006 64 Female 5/25/2010 United Kingdom
Primary
Concomitant
Fatigue Disability 4/24/2010 81 Female 5/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2006 64 Female 182 lb 5/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Tachycardia Other Serious 58 Male 6/10/2010 Physician United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 6/7/2010 United States
Primary
Concomitant
Presyncope Other Serious 58 Male 6/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 62 Male 6/17/2010 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 2/1/2010 84 Female 97 lb 6/17/2010 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 9/19/2008 86 Male 6/21/2010 Consumer Switzerland
Primary
Concomitant
Atrial Tachycardia Other Serious 58 Male 6/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Atrial Tachycardia Other Serious 58 Male 6/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 5/1/2008 83 Male 6/23/2010 Other Health Professional Canada
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 10/7/2009 66 Male 241 lb 6/23/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 60 Female 99 lb 6/24/2010 Other Health Professional Canada
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/7/2009 66 Male 241 lb 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hyperhidrosis 1/27/2007 66 Female 172 lb 7/9/2010 Consumer United States
Primary
Concomitant
Nausea 3/1/2007 Female 7/12/2010 Consumer United States
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 7/1/2006 53 Male 7/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sinus Bradycardia Other Serious 73 Female 88 lb 7/27/2010 Other Health Professional Japan
Primary
Secondary
Myocardial Ischaemia Other Serious 7/1/2010 51 Male 7/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 74 Female 148 lb 7/26/2010 Consumer United States
Primary
Concomitant
Sinus Bradycardia Other Serious 73 Female 88 lb 8/3/2010 Other Health Professional Japan
Primary
Secondary
Renal Failure Chronic Hospitalization 41 Male 8/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 41 Male 8/17/2010 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 41 Male 8/17/2010 United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 70 Female 8/24/2010 Other Health Professional United States
Primary
Concomitant
Facial Paresis Other Serious 8/9/2010 70 Male 231 lb 9/3/2010 Consumer Finland
Primary
Concomitant
Renal Failure Hospitalization 10/2/2009 86 Male 161 lb 9/6/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 73 Female 88 lb 9/8/2010 Other Health Professional Japan
Primary
Secondary
Myocardial Ischaemia Other Serious 7/1/2010 51 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 7/13/2010 75 Male 9/13/2010 Physician Hong Kong
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/2/2010 76 Male 170 lb 9/28/2010 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2010 51 Male 10/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 70 Female 228 lb 10/6/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 64 Male 169 lb 10/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 2/1/2010 84 Female 97 lb 10/11/2010 United Kingdom
Primary
Concomitant
Diabetes Mellitus Other Serious 10/1/2009 55 Female 123 lb 10/14/2010 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/11/2010 72 Female 196 lb 10/20/2010 Physician United Kingdom
Primary
Concomitant
Haematemesis Death 10/17/2010 61 Male 10/21/2010 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Other Serious 10/1/2009 55 Female 123 lb 11/8/2010 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 6/14/2010 57 Male 11/1/2010 United Kingdom
Primary
Concomitant
Viral Myositis Other Serious 2/1/2009 68 Male 117 lb 11/16/2010 Physician Finland
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 11/10/2010 73 Male 181 lb 11/19/2010 Other Health Professional Sweden
Primary
Concomitant
Muscle Spasms Hospitalization 11/10/2010 73 Male 181 lb 11/23/2010 Other Health Professional Sweden
Primary
Concomitant
Vomiting Other Serious 11/14/2010 80 Female 118 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Nasal Congestion Male 200 lb 11/30/2010 Consumer United States
Primary
Concomitant
Diabetes Mellitus Other Serious 10/1/2009 55 Female 123 lb 12/10/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2010 76 Female 12/22/2010 Physician Canada
Primary
Concomitant
Muscle Spasms Other Serious 64 Female 12/10/2010 Pharmacist Denmark
Primary
Secondary
Concomitant
Atrial Flutter Other Serious 74 Male 12/29/2010 Pharmacist Ireland
Primary
Concomitant
Neoplasm Malignant Death 6/1/2010 69 Female 1/3/2011 Physician Poland
Primary
Concomitant
Diabetes Mellitus Other Serious 10/1/2009 55 Female 148 lb 1/4/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 12/11/2010 78 Male 157 lb 1/6/2011 Physician Italy
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 64 Female 1/14/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 64 Female 1/10/2011 Pharmacist Denmark
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/25/2010 78 Male 157 lb 1/23/2011 Physician Italy
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious Male 1/24/2011 Physician Switzerland
Primary
Concomitant
Drug Interaction 63 Male 273 lb 1/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Other Serious Female 1/31/2011 Physician Canada
Primary
Secondary
Concomitant
Pancreatitis Other Serious 12/6/2010 64 Male 2/1/2011 Physician Ireland
Primary
Concomitant
Cardiac Failure Congestive Other Serious 11/29/2010 Male 207 lb 2/2/2011 Physician Canada
Primary
Secondary
Concomitant
Gastric Cancer Death Male 2/14/2011 Physician United Kingdom
Primary
Concomitant
Off Label Use Other Serious 73 Female 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 1/1/2011 79 Female 132 lb 2/22/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/22/2011 79 Female 2/21/2011 Other Health Professional
Primary
Concomitant
Myositis Other Serious Male 2/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Death 2/5/2010 77 Male 3/15/2011 Consumer United Kingdom
Primary
Concomitant
Diabetic Retinopathy Other Serious 12/31/2010 52 Female 203 lb 3/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Death 2/5/2010 77 Male 3/28/2011 Physician United Kingdom
Primary
Concomitant
Hypertension Other Serious 10/1/2009 55 Female 228 lb 4/5/2011 Consumer United States
Primary
Concomitant
Sopor Hospitalization 4/6/2011 71 Male 4/18/2011 Physician Russian Federation
Primary
Concomitant
Treatment Noncompliance Other Serious 10/1/2009 55 Female 228 lb 4/19/2011 Consumer United States
Primary
Concomitant
Sopor Hospitalization 4/6/2011 71 Male 4/29/2011 Physician Russian Federation
Primary
Concomitant
Neck Pain Other Serious 63 Female 4/29/2011 Other Health Professional Ireland
Primary
Concomitant
Tremor Other Serious 3/1/2011 Female 5/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 4/5/2010 77 Male 183 lb 5/9/2011 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 4/9/2011 77 Male 139 lb 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 6/1/2011 78 Male 7/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 6/6/2011 78 Male 7/25/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 6/1/2011 78 Male 8/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 4/28/2010 Female 154 lb 8/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/1/2011 78 Male 8/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 6/1/2011 78 Male 9/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Death 57 Female 126 lb 9/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthenia Hospitalization 3/1/2009 60 Female 99 lb 11/14/2011 Other Health Professional Canada
Primary
Concomitant
Atrial Flutter Life Threatening 7/27/2011 68 Male 196 lb 12/1/2011 Physician United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 4/25/2011 75 Male 1/6/2012 Physician Japan
Primary
Concomitant
Gout Other Serious 9/9/2011 63 Male 1/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Gout Other Serious 9/9/2011 63 Male 1/31/2012 Other Health Professional United Kingdom
Primary
Concomitant
Feeling Abnormal Other Serious 68 Male 172 lb 2/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dissociation Other Serious 68 Male 172 lb 2/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 68 Male 172 lb 2/21/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 2/26/2012 72 Male 207 lb 3/15/2012 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 1/1/2012 64 Male 170 lb 3/16/2012 Consumer United States
Primary
Concomitant

Drug Data