Bisoprolol combined with Tramadol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Palpitations Other Serious 1/13/2006 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 7/15/2005 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 12/3/2008 1/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious Male 179 lb 4/8/2009 Germany
Primary
Concomitant
Unresponsive To Stimuli Other Serious Male 179 lb 4/8/2009 Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 4/2/2009 Male 4/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2008 72 5/29/2009 Denmark
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/11/2008 Male 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 5/1/2009 67 Male 216 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2008 72 7/30/2009 Denmark
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Transaminases Increased Hospitalization 12/3/2008 70 9/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2008 Male 10/2/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/10/2009 88 Female 1/8/2010 Other Health Professional France
Primary
Concomitant
Nephrotic Syndrome Hospitalization 1/1/2009 75 Male 2/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Visual Impairment Other Serious 9/1/2006 Female 2/10/2010 Other Health Professional United States
Primary
Concomitant
Skin Irritation Other Serious 8/1/2006 Male 229 lb 2/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 6/26/2008 Male 197 lb 2/12/2010 Physician France
Primary
Concomitant
Neutrophil Count Increased Hospitalization 1/11/2010 51 Male 168 lb 7/16/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/20/2010 Physician Belgium
Primary
Secondary
Concomitant
Impaired Gastric Emptying Hospitalization 3/17/2010 41 Male 273 lb 7/21/2010 Physician Denmark
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 7/1/2009 83 Female 99 lb 8/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/24/2010 Consumer United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 6/1/2010 75 Male 9/28/2010 Consumer United Kingdom
Primary
Concomitant
Chills Other Serious 71 Female 10/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Cord Compression Other Serious 9/23/2009 60 Male 172 lb 11/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/21/2010 74 Male 200 lb 11/29/2010 Pharmacist Ireland
Primary
Concomitant
Tremor Other Serious 71 Female 117 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 9/1/2009 69 Male 165 lb 12/13/2010 Consumer Netherlands
Primary
Concomitant
Fungal Infection Hospitalization 9/1/2009 69 Male 165 lb 1/12/2011 Consumer Netherlands
Primary
Concomitant
Osteoarthritis Other Serious Male 3/30/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 1/1/2009 75 Male 3/30/2011 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/1/2010 67 Male 4/4/2011 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Myocardial Infarction Hospitalization 2/6/2011 84 Female 4/7/2011 Consumer Switzerland
Primary
Concomitant
Drug Interaction Life Threatening 7/1/2010 67 Male 4/8/2011 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Osteoarthritis Other Serious 64 Male 223 lb 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 7/1/2010 67 Male 6/7/2011 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Embolism Life Threatening 11/1/2011 68 Male 12/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psoriasis Other Serious 11/1/2010 64 Male 223 lb 1/19/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psoriasis Other Serious 11/1/2010 64 Male 223 lb 1/19/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Gout Other Serious 9/9/2011 63 Male 1/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Gout Other Serious 9/9/2011 63 Male 1/31/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Cirrhosis Other Serious 6/1/2011 63 Female 234 lb 7/17/2012 Consumer United States
Primary
Secondary
Concomitant
Angiodysplasia Hospitalization 12/9/2010 80 Female 7/23/2012 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 6/1/2011 63 Female 234 lb 8/22/2012 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/11/2011 70 Male 206 lb 11/12/2012 Physician Es
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 11/2011 68 Male 6/26/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Anger Other Serious 10/7/2011 76 Male 5/8/2013 Pharmacist Gb
Primary
Concomitant
Tinea Pedis 2006 Female 183 lb 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Wound Infection Death 1/25/2012 73 Female 12/3/2012 Consumer Country Not Specified
Primary
Concomitant
Urinary Tract Infection Other Serious 4/13/2012 62 Female 238 lb 11/26/2012 Physician De
Primary
Concomitant
Organising Pneumonia Hospitalization 4/19/2012 76 Male 10/24/2012 Physician Ca
Primary
Concomitant
Metastases To Meninges Life Threatening 5/3/2012 71 Male 143 lb 9/24/2013 Consumer De
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 2/13/2011 62 Male 143 lb 8/2/2013 Physician Fr
Primary
Secondary
Concomitant
Vasculitis Other Serious 5/8/2012 79 Female 122 lb 10/17/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 8/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 10/24/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 4/2012 Male 231 lb 11/5/2012 Physician Gb
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/2/2012 79 Female 122 lb 6/20/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 74 Male 9/17/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 7/2012 50 Female 152 lb 12/19/2013 Us
Primary
Secondary
Concomitant
Delirium Other Serious 2/19/2012 68 Male 176 lb 8/29/2012 Physician De
Primary
Concomitant
Delirium Required Intervention 68 Male 8/24/2012 Gb
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/2012 Female 130 lb 12/6/2012 Consumer Us
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 9/1/2012 57 Female 9/27/2012 Us
Primary
Concomitant
Gastroenteritis Hospitalization 5/28/2012 70 Male 166 lb 10/4/2012 Other Health Professional Pl
Primary
Concomitant
Pain In Extremity Other Serious 9/19/2012 61 Female 243 lb 10/11/2012 Other Health Professional Gb
Primary
Concomitant
Swelling Face Hospitalization 10/2012 Female 11/4/2012 Pharmacist Gb
Primary
Concomitant
Rash Pruritic Other Serious 10/28/2012 59 Male 192 lb 12/28/2012 Consumer Us
Primary
Secondary
Concomitant
Pollakiuria 10/28/2012 59 Male 192 lb 11/12/2012 Consumer Us
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 2012 84 Male Pharmacist De
Primary
Concomitant
Somnolence Hospitalization 10/31/2012 51 Female 11/29/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 11/2012 76 Male 12/21/2012 Physician Es
Primary
Concomitant
Toxicity To Various Agents Death 1/4/2011 64 Male 12/4/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Pyelonephritis Other Serious 11/22/2012 69 Female 12/21/2012 Other Health Professional Fr
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 60 Female 157 lb 12/13/2012 Physician Es
Primary
Concomitant
C-reactive Protein Increased Hospitalization 11/13/2012 69 Female 1/18/2013 Other Health Professional It
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Stage 0 Other Serious 2/11/2010 71 Male 12/20/2012 Physician Gb
Primary
Concomitant
Lactic Acidosis Death 10/9/2011 74 Male 12/19/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 11/27/2012 61 12/20/2012 Pharmacist Gb
Primary
Concomitant
Lactic Acidosis Death 10/9/2011 73 Male 12/21/2012 Consumer De
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 11/11/2012 73 Female 12/21/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 11/11/2012 73 Female 9/25/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 11/27/2012 61 12/24/2012 Pharmacist Gb
Primary
Concomitant
Lactic Acidosis Death 10/9/2011 73 Male 12/26/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 11/27/2012 61 1/2/2013 Pharmacist Gb
Primary
Concomitant
Hyponatraemia Hospitalization 11/11/2012 73 Female 12/28/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 11/11/2012 73 Female 10/7/2013 Consumer Gb
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 11/27/2012 61 12/31/2012 Pharmacist Gb
Primary
Concomitant
Skin Exfoliation Other Serious 11/27/2012 61 NotSpecified 1/2/2013 Other Health Professional Gb
Primary
Concomitant
Lactic Acidosis Death 10/9/2011 74 Male 1/2/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Skin Reaction Other Serious 12/2012 61 Male 220 lb 8/5/2013 Physician Country Not Specified
Primary
Concomitant
Tremor Hospitalization 11/5/2012 78 Male 1/18/2013 Consumer Fr
Primary
Secondary
Concomitant
Injection Site Haemorrhage 8/3/2012 59 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Neck Pain 6/2012 45 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Dyspnoea Other Serious 70 Female 154 lb 2/21/2013 Other Health Professional Gb
Primary
Concomitant
Weight Decreased Hospitalization 2012 83 Female 160 lb 1/25/2013 Other Health Professional Se
Primary
Secondary
Concomitant
Purpura Hospitalization 1/21/2013 71 Male 2/28/2013 Consumer Jp
Primary
Concomitant
Sneezing Disability 2/4/2013 59 Female 168 lb 3/7/2013 Other Health Professional Gb
Primary
Concomitant
Haematochezia Hospitalization 1/22/2013 78 Male 135 lb 3/8/2013 Pharmacist Gb
Primary
Concomitant
Toxicity To Various Agents Hospitalization 11/29/2012 55 Male 3/11/2013 Other Health Professional Se
Primary
Secondary
Concomitant
Sneezing Disability 2/4/2013 59 Female 168 lb 3/15/2013 Physician Gb
Primary
Concomitant
Sneezing Disability 2/4/2013 59 Female 168 lb 3/15/2013 Physician Gb
Primary
Concomitant
Sneezing Disability 2/4/2013 59 Female 168 lb 3/14/2013 Other Health Professional Gb
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 67 Male 3/22/2013 Other Health Professional Gb
Primary
Concomitant
Back Pain Hospitalization 2/27/2013 66 Female 8/9/2013 Consumer Nl
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 67 Male 3/27/2013 Consumer Gb
Primary
Concomitant
Angina Pectoris Hospitalization 2/28/2013 79 Female 171 lb 4/5/2013 Physician Gb
Primary
Concomitant
Sudden Death Hospitalization 3/23/2013 59 Female 176 lb 7/16/2013 Physician Be
Primary
Secondary
Concomitant
Hallucination, Visual Hospitalization 3/3/2013 64 Male 4/19/2013 Other Health Professional Gb
Primary
Concomitant
Syncope Hospitalization 75 Male 4/21/2013 Physician Gb
Primary
Concomitant
Hallucination, Visual Hospitalization 3/3/2013 64 Male 4/23/2013 Other Health Professional Gb
Primary
Concomitant
Sneezing Disability 2/4/2013 59 Female 168 lb 4/26/2013 Physician Gb
Primary
Concomitant
Sneezing Disability 59 Female 168 lb 3/13/2013 Consumer Gb
Primary
Concomitant
Lactic Acidosis Death 10/9/2011 73 Male 12/28/2012 Pharmacist Dk
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/18/2013 66 Female 249 lb 5/21/2013 Other Health Professional Gb
Primary
Concomitant
Neutropenic Sepsis Hospitalization 4/18/2013 NotSpecified 7/2/2013 Physician Gb
Primary
Secondary
Concomitant
Pyrexia 5/20/2013 80 Female 160 lb Us
Primary
Secondary
Concomitant
Rash Other Serious 8/2012 50 Female 7/2/2013 Pharmacist Ie
Primary
Concomitant
Transaminases Increased Life Threatening 2/3/2013 67 Female 7/12/2013 Physician Se
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Disability 6/18/2013 91 Female 126 lb 7/19/2013 Other Health Professional Gb
Primary
Concomitant
Thrombocytopenia Hospitalization 6/6/2013 63 Male 7/22/2013 Other Health Professional Fr
Primary
Concomitant
Palpitations Hospitalization 5/16/2013 59 Female 143 lb 7/22/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Disability 6/18/2013 91 Female 126 lb 7/29/2013 Physician Gb
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Disability 6/18/2013 91 Female 126 lb 7/29/2013 Physician Gb
Primary
Concomitant
Sensory Disturbance Hospitalization 7/4/2013 81 Female 192 lb 8/1/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Tearfulness Life Threatening 7/10/2013 NotSpecified 8/12/2013 Other Health Professional Gb
Primary
Concomitant
Tearfulness Life Threatening 7/10/2013 45 Male 265 lb 8/16/2013 Physician Jp
Primary
Concomitant
Hallucination Hospitalization 2/20/2010 89 Male 8/24/2013 Other Health Professional Gb
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 1/26/2012 55 Male 137 lb 8/27/2013 Consumer Gb
Primary
Secondary
Concomitant
Hallucination Hospitalization 2/20/2010 89 Male 8/27/2013 Pharmacist Gb
Primary
Concomitant
Sepsis Hospitalization 3/4/2013 80 Female 126 lb 10/8/2013 Physician De
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/5/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 78 Male 9/7/2013 Physician Se
Primary
Secondary
Concomitant
Weight Bearing Difficulty Life Threatening 8/17/2013 73 Male 9/6/2013 Consumer Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/16/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Life Threatening 8/17/2013 73 Male 9/18/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Rash Generalised Other Serious 8/19/2013 65 Male 247 lb 9/19/2013 Consumer Gb
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious Female 10/25/2013 Other Health Professional Gb
Primary
Concomitant
Wheezing Life Threatening 9/10/2013 86 Female 140 lb 10/9/2013 Other Health Professional Gb
Primary
Concomitant
Swelling Face Other Serious 8/28/2013 NotSpecified 9/27/2013 Other Health Professional Gb
Primary
Concomitant
Rash Other Serious 8/17/2013 70 Female 154 lb 10/7/2013 Physician Gb
Primary
Concomitant
Swelling Face Other Serious 8/28/2013 65 Female 154 lb 10/9/2013 Other Health Professional Gb
Primary
Concomitant
Wheezing Life Threatening 9/10/2013 86 Female 141 lb 10/10/2013 Consumer Gb
Primary
Concomitant
Neutropenia Hospitalization 10/11/2011 70 Male 206 lb 12/8/2013 Physician Es
Primary
Secondary
Concomitant

Drug Data