Bisoprolol combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 1/12/2006 Czech Republic
Primary
Secondary
Concomitant
Ventricular Failure Required Intervention 12/1/2005 Female 2/8/2006 Physician Netherlands
Primary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Left Ventricular Failure Hospitalization 11/24/2005 75 Male 154 lb 2/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin T Increased Hospitalization 11/24/2005 75 Male 154 lb 3/10/2006 United Kingdom
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 52 Female 3/16/2006 Physician France
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 3/31/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 4/27/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/8/2002 56 Female 154 lb 5/3/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/19/2006 83 Female 112 lb 5/23/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 6/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2004 65 Male 176 lb 6/5/2006 Netherlands
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 6/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 139 lb 3/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 139 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 3/7/2007 72 Male 4/4/2007 Physician United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 3/28/2007 75 Male 4/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 58 Male 6/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/1/2005 81 Female 6/27/2007 United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization 12/4/2006 Female 198 lb 7/12/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/11/2007 79 Female 201 lb 7/14/2007 Physician Germany
Primary
Secondary
Concomitant
Lipids Abnormal Other Serious 6/1/2007 70 Female 121 lb 7/19/2007 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Other Serious 58 Male 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 8/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 8/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 8/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 8/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 8/16/2007 74 Male 198 lb 9/5/2007 Physician
Primary
Concomitant
Renal Failure Hospitalization 58 Male 9/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Disability 65 9/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 58 Male 9/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 11/24/2005 75 Male 154 lb 9/7/2007 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psoriasis Other Serious 3/29/2007 Male 9/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 58 Male 9/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Psoriasis Other Serious 3/29/2007 Male 9/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Other Serious 3/29/2007 Male 9/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Other Serious 7/1/2007 65 Male 195 lb 9/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 58 Male 9/28/2007 United Kingdom
Primary
Concomitant
Interacting
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 3/20/2007 69 Male 258 lb 10/1/2007 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/26/2006 Female 117 lb 12/28/2007 Physician Ireland
Primary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 73 Male 212 lb 5/9/2008 Physician United Kingdom
Primary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 5/13/2008 Germany
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 6/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 7/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2008 Female 276 lb 10/6/2008 Physician Belgium
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 74 Male 10/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 1/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Pulmonary Hypertension Life Threatening 11/27/2008 Female 1/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sensory Loss Other Serious 58 Male 1/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Renal Failure Other Serious 58 Male 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 1/1/2007 Male 172 lb 1/26/2009 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 58 Male 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 80 Female 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Weight Increased Other Serious 1/1/2008 44 Male 362 lb 2/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 10/28/2008 Female 159 lb 2/18/2009 Belgium
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/23/2009 Other Health Professional Italy
Primary
Concomitant
Ventricular Dysfunction Other Serious 61 Male 2/24/2009 Physician United States
Primary
Concomitant
Oedema Other Serious 1/1/2008 Male 126 lb 2/26/2009 Physician Germany
Primary
Concomitant
Hallucination Other Serious 2/10/2009 3/2/2009 Physician Belgium
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Life Threatening 11/27/2008 Female 3/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2008 43 Female 362 lb 3/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Life Threatening 3/6/2008 77 Male 176 lb 3/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/1/2008 74 Male 3/6/2009 Physician Switzerland
Primary
Concomitant
Interacting
Hyperkalaemia Hospitalization 11/17/2008 76 Male 161 lb 3/6/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2007 43 Female 362 lb 3/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 10/20/2008 67 Female 3/9/2009 Other Health Professional France
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 10/10/2008 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 44 Male 360 lb 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 44 Male 360 lb 3/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Pain Hospitalization 5/1/2007 43 Female 360 lb 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 43 Female 362 lb 3/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/13/2008 44 Male 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 3/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/27/2008 74 Female 3/31/2009
Primary
Secondary
Concomitant
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 4/1/2009 Consumer United Kingdom
Primary
Secondary
Left Ventricular Dysfunction Life Threatening 11/27/2008 Female 4/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 86 Female 4/20/2009 Physician Finland
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 4/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 86 Female 5/1/2009 Physician Finland
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 86 Female 5/13/2009 Physician Finland
Primary
Secondary
Concomitant
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 5/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Alkalosis Life Threatening 9/2/2008 51 Female 203 lb 5/22/2009 Consumer Germany
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Life Threatening 11/27/2008 Female 5/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 3/20/2007 69 Male 258 lb 6/5/2009 Other Health Professional Canada
Primary
Concomitant
Renal Failure Chronic Life Threatening 8/20/2008 71 Female 6/10/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 362 lb 7/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/1/2009 67 Male 7/1/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 7/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 362 lb 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/14/2009 56 Male 8/6/2009 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 7/31/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 74 8/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/9/2009 56 Male 8/18/2009 Consumer France
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 8/20/2009 United Kingdom
Primary
Secondary
Concomitant
Sensory Loss Other Serious 58 Male 8/20/2009 United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 8/12/2009 Female 9/4/2009 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 43 Female 362 lb 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 10/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 10/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/4/2009
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 43 Female 362 lb 11/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 11/10/2009 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 359 lb 11/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 11/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Other Serious 9/17/2009 12/1/2009 Physician Belgium
Primary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2006 Female 117 lb 11/30/2009 Physician Ireland
Primary
Concomitant
Angina Pectoris Hospitalization 1/1/2007 Male 172 lb 12/1/2009 Physician Germany
Primary
Concomitant
Bile Duct Cancer Life Threatening 70 Female 143 lb 12/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 Female 12/11/2009 Physician Germany
Primary
Concomitant
Jaundice Hospitalization 4/1/2009 78 Male 185 lb 12/14/2009 Physician Germany
Primary
Concomitant
Heart Rate Decreased Other Serious Male 12/14/2009 Other Health Professional Canada
Primary
Concomitant
Death Death 11/19/2009 Male 12/17/2009 Physician United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 1/1/2004 63 Male 12/14/2009 Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 11/19/2009 Male 12/21/2009 Physician United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 10/18/2009 Female 214 lb 1/7/2010 Consumer France
Primary
Concomitant
Fatigue Other Serious 12/2/2009 Male 1/20/2010 Other Health Professional Sweden
Primary
Concomitant
Pruritus Other Serious 63 Female 2/9/2010 Other Health Professional Poland
Primary
Concomitant
Left Ventricular Failure Hospitalization 8/15/2009 Female 214 lb 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Life Threatening 10/13/2009 Female 3/2/2010 Physician Hungary
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious Male 3/4/2010 Other Health Professional Canada
Primary
Concomitant
Neutropenia Hospitalization 11/17/2009 82 Female 3/9/2010 Physician Germany
Primary
Secondary
Concomitant
Lymphoma Hospitalization 10/24/2008 Male 150 lb 3/19/2010 Physician Canada
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 9/1/2009 231 lb 3/22/2010 Physician Germany
Primary
Concomitant
Thrombosis In Device Hospitalization 1/29/2010 Male 134 lb 3/22/2010 Physician Bulgaria
Primary
Concomitant
Ventricular Fibrillation Life Threatening 1/25/2010 Male 134 lb 3/19/2010 Physician Bulgaria
Primary
Concomitant
Ventricular Fibrillation Life Threatening 1/25/2010 Male 134 lb 3/26/2010 Physician Bulgaria
Primary
Concomitant
Thrombosis In Device Life Threatening 1/29/2010 44 Male 134 lb 4/1/2010 Physician Bulgaria
Primary
Concomitant

Drug Data