Bisoprolol combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Uterine Dilation And Curettage Other Serious 2/1/2007 Female 128 lb 3/22/2007 Consumer United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ileus Paralytic Hospitalization 1/1/2006 Male 95 lb 3/29/2007 Physician Germany
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 72 Male 9/7/2007 Consumer United States
Primary
Secondary
Concomitant
Colitis Hospitalization 7/20/2007 61 Male 9/18/2007 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/1/2005 Female 9/19/2007 Pharmacist
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 7/9/2007 70 Male 196 lb 1/7/2008 Physician Australia
Primary
Secondary
Concomitant
Sudden Death Death 4/5/2007 57 Female 1/10/2008 Physician Belgium
Primary
Concomitant
Sudden Death Death 4/5/2007 57 Female 1/10/2008 Physician Belgium
Primary
Concomitant
Throat Tightness 1/10/2008 Female 2/1/2008 Consumer United States
Primary
Concomitant
Oral Candidiasis 1/1/2007 Female 1/28/2009 Consumer
Primary
Concomitant
Urine Colour Abnormal Other Serious 1/1/2009 73 Female 2/1/2009 Pharmacist Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 10/20/2008 67 Female 2/17/2009
Primary
Secondary
Concomitant
Oral Fungal Infection 1/1/2007 Female 2/17/2009 Consumer
Primary
Concomitant
Renal Failure Acute Hospitalization 10/14/2008 67 Female 2/26/2009 Consumer France
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/3/2009 Male 3/4/2009 Other Health Professional Switzerland
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 8/16/2008 54 Male 3/12/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Weight Increased 67 Female 126 lb 3/18/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 5/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 4/16/2009 Female 5/13/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 4/19/2009 76 Male 5/15/2009 Other Health Professional Germany
Primary
Concomitant
Sudden Death Death 5/7/2009 61 5/22/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 6/15/2009 Other Health Professional Germany
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/1/2008 66 Female 7/1/2009 Physician Germany
Primary
Concomitant
Interacting
Throat Irritation Hospitalization 59 Male 224 lb 8/5/2009 Consumer Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 12/29/2008 Female 8/6/2009 Physician Canada
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Hospitalization 12/11/2008 51 Male 8/13/2009 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Female 8/22/2009 United States
Primary
Concomitant
Lymphocyte Count Decreased Disability 1/4/2009 63 Male 154 lb 9/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypovolaemia Hospitalization 4/16/2009 Female 97 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 4/19/2009 76 Male 240 lb 10/12/2009 Other Health Professional Germany
Primary
Concomitant
Weight Increased 67 Female 126 lb 10/12/2009 United States
Primary
Concomitant
Sepsis Other Serious 12/29/2008 Female 10/28/2009 Physician Canada
Primary
Concomitant
Nausea Other Serious 4/17/2008 Female 105 lb 12/1/2009 Physician Canada
Primary
Concomitant
Encephalopathy Hospitalization 8/29/2009 70 Male 12/4/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Fatigue Other Serious 12/2/2009 72 Male 12/17/2009 Other Health Professional Sweden
Primary
Concomitant
Mental Status Changes Hospitalization 4/16/2009 Female 97 lb 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Fatigue Other Serious 12/2/2009 72 Male 12/30/2009 Other Health Professional Sweden
Primary
Concomitant
Fatigue Other Serious 12/2/2009 Male 1/20/2010 Other Health Professional Sweden
Primary
Concomitant
Thrombocytopenia Other Serious 12/1/2009 82 Male 2/12/2010 Physician France
Primary
Secondary
Concomitant
Death Death Male 190 lb 2/15/2010 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 4/20/2009 74 Female 3/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/28/2009 70 Male 4/23/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Myocardial Infarction Other Serious Male 238 lb 4/27/2010 Physician Germany
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Death Male 190 lb 5/6/2010 Physician United States
Primary
Concomitant
Dyspnoea Death 4/8/2009 72 Male 238 lb 5/7/2010 Italy
Primary
Concomitant
Vertigo Hospitalization 69 Male 5/11/2010 Lawyer United States
Primary
Concomitant
Urine Albumin/creatinine Ratio Other Serious 3/11/2010 50 Male 5/27/2010 Physician Canada
Primary
Concomitant
Spinal Fracture Hospitalization 80 Female 198 lb 6/18/2010
Primary
Concomitant
Metastases To Liver Hospitalization 2/25/2010 72 Male 168 lb 6/25/2010 Physician Germany
Primary
Concomitant
Hypotension Hospitalization 5/7/2010 86 Male 7/6/2010 Physician Sweden
Primary
Secondary
Concomitant
Psoriasis Hospitalization 4/27/2010 71 Male 7/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious Female 7/12/2010 Physician Germany
Primary
Concomitant
Oesophageal Spasm 12/1/2007 61 Female 145 lb 7/19/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 7/1/2010 70 Male 278 lb 7/29/2010 Physician Germany
Primary
Concomitant
Venous Insufficiency Other Serious 76 Female 7/26/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 6/6/2010 77 Female 8/9/2010 Consumer Argentina
Primary
Concomitant
Respiratory Failure Other Serious Male 147 lb 8/23/2010 Physician Germany
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 8/14/2010 84 Male 9/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 9/9/2010 59 Female 93 lb 9/29/2010 Consumer Hungary
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 8/14/2010 84 Male 10/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 9/1/2010 Male 10/6/2010 Consumer Germany
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 9/7/2010 84 Male 185 lb 11/4/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Life Threatening Male 11/9/2010 Physician Netherlands
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 12/3/2010 Pharmacist Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 12/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Dehydration Life Threatening 8/16/2008 54 Male 172 lb 12/7/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Dehydration Life Threatening 8/16/2008 54 Male 172 lb 12/7/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Off Label Use Life Threatening 10/10/2010 69 Female 181 lb 12/8/2010 Physician Germany
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 9/7/2010 84 Male 185 lb 12/8/2010 Physician
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 12/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 9/7/2010 84 Male 185 lb 12/9/2010 Physician Germany
Primary
Concomitant
Interacting
Prothrombin Time Prolonged Hospitalization 8/16/2008 54 Male 12/14/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Off Label Use Life Threatening 10/10/2010 69 Female 181 lb 12/14/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 10/24/2010 71 Female 12/15/2010 Other Health Professional France
Primary
Concomitant
Jaundice Life Threatening 10/10/2010 69 Female 181 lb 12/16/2010 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 12/14/2010 64 Male 198 lb 12/20/2010 Other Health Professional Finland
Primary
Concomitant
Oral Fungal Infection 1/1/2007 65 Female 12/28/2010 Consumer
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 12/29/2010 Physician Netherlands
Primary
Concomitant
Pneumonia Hospitalization 12/14/2010 64 Male 187 lb 1/3/2011 Other Health Professional Finland
Primary
Concomitant
Death Hospitalization 12/8/2010 65 Female 142 lb 12/28/2010 Consumer Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 12/8/2010 65 Female 141 lb 1/6/2011 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/24/2010 71 Female 1/7/2011 Other Health Professional France
Primary
Concomitant
C-reactive Protein Increased Hospitalization 12/2/2009 76 Male 265 lb 1/18/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Haematochezia 1/6/2011 69 Male 1/21/2011 Consumer
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 12/2/2009 76 Male 265 lb 1/26/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Clostridium Difficile Colitis Hospitalization 11/26/2009 76 Male 265 lb 1/27/2011 Consumer Germany
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 12/2/2009 76 Male 265 lb 1/31/2011 Physician Germany
Primary
Concomitant
Interacting
Renal Failure Hospitalization 1/6/2009 74 Female 2/2/2011 Consumer Sweden
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 11/1/2010 65 Male 2/3/2011 Physician Finland
Primary
Concomitant
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 2/7/2011 Consumer Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/14/2010 64 Male 187 lb 2/10/2011 Other Health Professional Finland
Primary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 2/15/2011 Physician Netherlands
Primary
Concomitant
Skin Ulcer Hospitalization 77 Female 2/18/2011 Consumer Germany
Primary
Concomitant
Cardiac Failure Hospitalization 12/8/2010 65 Female 141 lb 2/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/8/2011 65 Male 186 lb 2/25/2011 Physician Finland
Primary
Concomitant
Pneumonia Hospitalization 2/8/2011 65 Male 186 lb 3/9/2011 Physician Finland
Primary
Concomitant
Chromaturia Disability 10/10/2010 69 Female 181 lb 3/18/2011 Physician Germany
Primary
Concomitant
Sudden Death Death 5/7/2009 61 Male 168 lb 3/31/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Medication Error Other Serious 9/9/2010 59 Female 93 lb 4/6/2011 Physician Hungary
Primary
Concomitant
Pneumonia Hospitalization 2/8/2011 65 Male 186 lb 4/7/2011 Physician Finland
Primary
Concomitant
Treatment Noncompliance Other Serious Female 121 lb 4/14/2011 Pharmacist Australia
Primary
Concomitant
Syncope Hospitalization 3/9/2009 60 Male 249 lb 6/23/2011 Physician Sweden
Primary
Concomitant
Sudden Death Death 5/7/2009 61 Male 168 lb 6/24/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 1/1/2011 68 Male 237 lb 6/20/2011 Pharmacist United States
Primary
Concomitant
Insomnia Other Serious 9/1/2011 47 Male 204 lb 9/9/2011 Consumer United States
Primary
Concomitant
Insomnia Other Serious 9/1/2011 47 Male 204 lb 9/13/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 9/3/2011 74 Male 159 lb 10/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 3/19/2011 79 Female 10/6/2011 Consumer Canada
Primary
Concomitant
Dyspnoea 9/18/2011 58 Female 10/11/2011 Consumer United States
Primary
Concomitant
Cough Other Serious 7/12/2010 55 Female 220 lb 10/19/2011 Physician Germany
Primary
Concomitant
Overdose Hospitalization 8/19/2011 74 Male 10/20/2011 Other Health Professional
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 7/15/2011 84 Female 11/16/2011 Physician France
Primary
Concomitant
Haematuria Hospitalization 12/26/2011 78 Male 169 lb 1/5/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 8/16/2008 54 Male 1/24/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Cardiac Failure Death 12/8/2010 65 Female 141 lb 2/1/2012 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 8/16/2008 54 Male 2/7/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious Female 80 lb 3/8/2012 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/5/2012 76 Male 5/1/2012 Physician Italy
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/5/2012 76 Male 5/14/2012 Physician Italy
Primary
Concomitant
Fall Death 5/30/2012 79 Male 8/14/2012 Physician Australia
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 5/10/2012 69 Male 175 lb 8/17/2012 Consumer Canada
Primary
Concomitant
Pulmonary Embolism Death 9/25/2011 73 Female 211 lb 5/30/2013 Consumer Us
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 9/25/2011 73 Female 211 lb 6/5/2013 Consumer Us
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/17/2011 77 Male 172 lb 9/25/2012 Physician De
Primary
Secondary
Concomitant
Weight Increased Hospitalization 2007 Female 238 lb 4/1/2013 Consumer Ca
Primary
Concomitant
Pancreatic Carcinoma Hospitalization 5/10/2012 69 Male 175 lb 10/12/2012 Consumer Ca
Primary
Concomitant
Pyrexia Hospitalization 9/15/2012 72 Female 106 lb 4/11/2013 De
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 6/1/2010 72 Male 134 lb 11/28/2012 Physician De
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/5/2012 63 Female 118 lb 1/23/2013 Consumer Country Not Specified
Primary
Concomitant
Sinus Tachycardia Other Serious Male 216 lb 10/8/2012 Consumer Us
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 3/5/2012 71 Male 12/3/2012 Physician Es
Primary
Secondary
Concomitant
Polymyositis Hospitalization 11/2012 81 Female 3/2/2013 Physician Se
Primary
Concomitant
Umbilical Hernia Other Serious 10/29/2012 58 Male 165 lb 2/6/2013 Other Health Professional Ca
Primary
Concomitant
Loss Of Consciousness Other Serious 12/7/2012 Female 12/19/2012 Consumer De
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 82 Male 1/12/2013 Other Health Professional Nl
Primary
Concomitant
Weight Decreased Hospitalization 12/22/2012 63 Female 236 lb 1/22/2013 Physician Nl
Primary
Secondary
Concomitant
Pupil Fixed Other Serious 1/1/2013 77 Male 1/11/2013 Physician Gb
Primary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 11/10/2012 69 Female 1/11/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Product Quality Issue Male 260 lb 2/5/2013 Consumer Us
Primary
Concomitant
Asthenia Hospitalization 12/21/2012 84 Female 2/5/2013 Other Health Professional It
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 1/17/2013 79 Male 200 lb 2/1/2013 Pharmacist Us
Primary
Concomitant
Death Other Serious 2/4/2013 64 Female 2/20/2013 Pharmacist De
Primary
Concomitant
Somnolence Other Serious 1/14/2013 Male 3/15/2013 Consumer De
Primary
Concomitant
Hemiparesis Life Threatening 11/2012 Male 306 lb 3/4/2013 Physician De
Primary
Concomitant
Urinary Bladder Haemorrhage Other Serious 11/12/2012 76 Male 160 lb 3/18/2013 Physician Country Not Specified
Primary
Concomitant
Fall Other Serious 1/28/2013 Female 3/18/2013 Consumer De
Primary
Concomitant
Weight Decreased Hospitalization Female 146 lb 3/20/2013 Consumer Ca
Primary
Concomitant

Drug Data