Bisoprolol combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Other Serious 9/1/2000 Male 1/10/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 12/1/2005 Female 164 lb 1/31/2006 Other Health Professional Canada
Primary
Concomitant
Renal Failure Life Threatening 1/23/2006 Male 192 lb 3/24/2006 Physician Germany
Primary
Concomitant
Weight Decreased 83 Female 160 lb 1/20/2006 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 3/7/2003 Female 126 lb 4/3/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Death Life Threatening 7/30/2005 47 Male 203 lb 4/4/2006 Physician Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/7/2006 Other Health Professional Canada
Primary
Concomitant
Myocardial Infarction Life Threatening 7/30/2005 53 Male 203 lb 4/19/2006 Physician Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/27/2006 Other Health Professional Canada
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 61 Male 4/28/2006 Physician Czech Republic
Primary
Concomitant
Electrocardiogram Qt Prolonged Death 78 Female 5/9/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 2/23/2006 65 Male 5/19/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 6/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 6/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2005 37 Male 6/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 12/19/2006 82 Female 157 lb 4/11/2007 Physician Austria
Primary
Concomitant
Weight Decreased Hospitalization 8/24/2006 55 Female 4/19/2007 Consumer United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Relapsing Hospitalization 4/21/2007 71 Male 229 lb 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 4/21/2006 71 Male 229 lb 6/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death 10/8/2007 50 Male 10/22/2007 Physician Russian Federation
Primary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 7/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/5/2008 65 Female 238 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 3/5/2008 65 Female 238 lb 9/9/2008 Physician United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 10/2/2008 59 Male 10/15/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 3/17/2008 75 Male 11/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Optic Neuritis Hospitalization 10/1/2008 58 Male 11/25/2008 Physician France
Primary
Secondary
Concomitant
Optic Neuritis Hospitalization 10/1/2008 58 Male 11/25/2008 Physician France
Primary
Secondary
Concomitant
Therapeutic Product Ineffective Other Serious 1/1/2008 35 Female 12/5/2008 Consumer Germany
Primary
Secondary
Concomitant
Optic Neuritis Hospitalization 10/1/2008 58 Male 12/9/2008 Physician France
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/4/2008 Male 191 lb 1/16/2009 Other Health Professional Canada
Primary
Concomitant
Interacting
Syncope Life Threatening 5/26/2008 1/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/18/2009 Female 2/2/2009 Pharmacist Canada
Primary
Concomitant
Resuscitation Other Serious 1/12/2009 Male 2/3/2009 Physician Canada
Primary
Concomitant
Presyncope Other Serious 1/1/2009 65 Male 2/25/2009 Consumer Germany
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2007 Male 4/8/2009 Consumer Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/1/2008 74 Male 209 lb 4/9/2009 Physician Germany
Primary
Concomitant
Syncope Life Threatening 5/26/2008 5/7/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Delirium Life Threatening 11/4/2008 67 Female 5/8/2009 Other Health Professional
Primary
Secondary
Concomitant
Sudden Death Death 5/7/2009 61 5/22/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/4/2008 57 5/28/2009 Other Health Professional Canada
Primary
Concomitant
Interacting
Cellulitis Hospitalization 4/1/2009 60 Female 6/10/2009 Pharmacist Canada
Primary
Concomitant
Pain Other Serious 1/1/2007 68 Male 7/28/2009 United Kingdom
Primary
Concomitant
Haemolysis Hospitalization 6/25/2009 59 Male 181 lb 8/4/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Thirst Other Serious 6/2/2009 Female 140 lb 8/11/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Dizziness 9/28/2008 Male 8/22/2009 United States
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/6/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/27/2009 Male 227 lb 11/12/2009 Physician Belgium
Primary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neuralgia Life Threatening 10/9/2009 88 Male 11/24/2009 United Kingdom
Primary
Concomitant
Shock Haemorrhagic Life Threatening 8/26/2009 80 Male 183 lb 12/9/2009 Physician Russian Federation
Primary
Concomitant
Stomatitis Hospitalization 9/1/2009 75 Female 170 lb 12/16/2009 Physician Germany
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 10/18/2009 Female 214 lb 1/7/2010 Consumer France
Primary
Concomitant
Optic Neuritis Hospitalization 10/1/2008 58 Male 1/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Hospitalization 10/7/2009 80 Male 2/12/2010 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 1/3/2010 62 Male 227 lb 2/15/2010 Other Health Professional Germany
Primary
Concomitant
Death Death Male 190 lb 2/15/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Disability 72 Female 2/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Disability 72 Female 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 2/17/2010 Male 123 lb 3/11/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Vertigo Hospitalization 2/22/2008 59 Female 3/19/2010 Other Health Professional Singapore
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 4/1/2010 74 Male 220 lb 4/9/2010 Physician Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2010 74 Male 220 lb 4/12/2010 Physician Spain
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 3/17/2010 4/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Disability 6/1/2009 64 Male 183 lb 4/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Hypertrophy Other Serious 11/25/2009 69 Male 220 lb 4/29/2010 Physician Germany
Primary
Concomitant
Syncope Hospitalization 5/26/2008 66 Male 234 lb 5/6/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Wheezing Hospitalization 56 Female 200 lb 4/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Syncope Hospitalization 5/26/2008 5/6/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Death Male 190 lb 5/6/2010 Physician United States
Primary
Concomitant
Syncope Life Threatening 5/26/2008 66 Male 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Syncope Life Threatening 5/26/2008 66 Male 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Syncope Life Threatening 5/26/2008 66 Male 5/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Vomiting Hospitalization 3/7/2009 64 Female 141 lb 5/6/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2009 64 Female 141 lb 5/6/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Life Threatening 5/26/2008 66 Male 234 lb 5/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Left Ventricular Hypertrophy Other Serious 11/25/2009 69 Male 220 lb 5/24/2010 Physician Germany
Primary
Concomitant
Optic Neuritis Hospitalization 10/1/2008 58 Male 5/25/2010 Other Health Professional France
Primary
Secondary
Concomitant
Breast Swelling Other Serious 3/12/2009 69 Male 5/25/2010 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 59 Male 192 lb 6/7/2010 Other Health Professional Canada
Primary
Concomitant
Vascular Dementia Other Serious 1/25/2010 72 Male 176 lb 6/11/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 5/7/2010 Female 187 lb 6/11/2010 Consumer Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/10/2010 64 Female 6/11/2010 Physician Italy
Primary
Concomitant
Interacting
Optic Neuritis Hospitalization 10/1/2008 58 Male 6/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Impaired Gastric Emptying Hospitalization 3/17/2010 41 Male 273 lb 7/21/2010 Physician Denmark
Primary
Concomitant
Status Epilepticus Other Serious 3/5/2009 67 Male 233 lb 8/3/2010 Germany
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 7/12/2010 50 Male 187 lb 8/24/2010 Physician Poland
Primary
Concomitant
Weight Decreased Other Serious 1/1/2010 78 Female 99 lb 8/27/2010 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Life Threatening 2/12/2010 65 Male 243 lb 8/27/2010 Physician United Kingdom
Primary
Concomitant
Skin Burning Sensation 6/26/2010 50 Male 243 lb 8/29/2010 Consumer United States
Primary
Concomitant
Somatoform Disorder Hospitalization 1/23/2009 61 Male 240 lb 9/9/2010 Physician Germany
Primary
Concomitant
Cerebral Ischaemia Hospitalization 8/18/2010 74 Female 154 lb 9/16/2010 Physician Germany
Primary
Concomitant
Neuralgia Life Threatening 10/9/2009 88 Male 9/16/2010 United Kingdom
Primary
Concomitant
Pancreatic Neoplasm Other Serious 7/21/2010 66 Male 9/15/2010 Physician United Kingdom
Primary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 9/8/2010 89 Female 9/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 11/4/2008 67 Female 9/22/2010 Other Health Professional
Primary
Secondary
Concomitant
Pregnancy Other Serious 6/20/2007 43 Female 255 lb 9/17/2010 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/7/2009 64 Female 141 lb 9/29/2010 Physician Germany
Primary
Concomitant
Urticaria Other Serious 8/16/2010 70 Female 143 lb 9/30/2010 Pharmacist Germany
Primary
Concomitant
Sudden Death Death 7/31/2010 52 Male 10/4/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Other Serious 8/16/2010 70 Female 143 lb 10/6/2010 Pharmacist Germany
Primary
Concomitant
Urinary Tract Infection 7/1/2010 59 Female 10/7/2010 Physician United States
Primary
Concomitant
Vomiting Life Threatening 6/1/2010 57 Female 10/8/2010 Other Health Professional France
Primary
Concomitant
Renal Cell Carcinoma Other Serious Female 359 lb 10/11/2010 Physician Netherlands
Primary
Concomitant
Empyema Hospitalization 8/4/2010 50 Male 183 lb 10/11/2010 Physician Poland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/8/2009 66 Male 10/15/2010 Physician United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 9/28/2010 80 187 lb 10/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Arrest Other Serious 9/17/2010 62 Male 10/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 7/31/2010 52 Male 10/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 6/1/2010 57 Female 10/28/2010 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 2/12/2010 65 Male 243 lb 10/29/2010 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Other Serious 9/17/2010 62 Male 10/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cataract Other Serious 9/1/2010 Male 11/4/2010 Consumer Germany
Primary
Concomitant
Cataract Other Serious 9/1/2010 Male 11/4/2010 Consumer Germany
Primary
Concomitant
Suicide Attempt Other Serious 79 187 lb 11/22/2010 Other Health Professional Germany
Primary
Concomitant
Suicide Attempt Other Serious 79 Male 187 lb 11/30/2010 Other Health Professional Germany
Primary
Concomitant
Wheezing Other Serious Male 261 lb 12/13/2010 Physician Canada
Primary
Concomitant
Faecal Incontinence Disability 1/1/2009 62 Female 258 lb 12/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Neuralgia Life Threatening 10/9/2009 88 Male 11/24/2009 United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Metastatic Life Threatening 10/1/2010 63 Female 209 lb 12/17/2010 Physician Russian Federation
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/21/2010 40 Male 12/21/2010 Pharmacist United Kingdom
Primary
Concomitant
Vulvovaginal Pruritus Other Serious Female 12/23/2010 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 73 Female 12/29/2010 Other Health Professional Canada
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 11/6/2010 70 Male 256 lb 1/13/2011 Physician United Kingdom
Primary
Concomitant
Pemphigoid Hospitalization 8/1/2010 77 Female 1/13/2011 Physician France
Primary
Concomitant
Drug Level Increased Life Threatening 11/5/2010 70 Female 1/18/2011 Other Health Professional Switzerland
Primary
Concomitant
Death Hospitalization 12/21/2010 84 Male 137 lb 2/2/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 1/20/2011 75 Male 2/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Other Serious 1/1/2010 70 Male 2/18/2011 Consumer Germany
Primary
Concomitant
Interacting
Thyroiditis Subacute Hospitalization 11/1/2010 52 Female 2/28/2011 Physician Germany
Primary
Concomitant
Chest Discomfort Hospitalization 76 Male 3/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 5/30/2010 66 Male 187 lb 3/23/2011 Physician Switzerland
Primary
Secondary
Concomitant
Sudden Death Death 5/7/2009 61 Male 168 lb 3/31/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 2/1/2011 59 Female 4/14/2011 Other Health Professional United States
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 2/1/2011 59 Female 4/14/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/13/2011 76 Male 4/4/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/14/2011 65 Male 152 lb 4/18/2011 Consumer Spain
Primary
Concomitant
Hyperglycaemia Other Serious 1/21/2010 63 Female 4/19/2011 Other Health Professional France
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 71 Female 7/21/2011 Other Health Professional Canada
Primary
Concomitant
Swelling Face Hospitalization 1/5/2011 64 Male 7/25/2011 Physician Germany
Primary
Concomitant
Malaise Other Serious 1/1/2009 78 Female 99 lb 7/28/2011 Physician United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 1/5/2011 64 Male 234 lb 8/2/2011 Physician Germany
Primary
Concomitant
Drug Level Increased Hospitalization 1/1/2011 55 Male 8/3/2011 Pharmacist Canada
Primary
Concomitant
Depressed Mood Other Serious 5/1/2011 49 Male 209 lb 8/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyperuricaemia Hospitalization 5/1/2011 71 Female 8/24/2011 Other Health Professional France
Primary
Secondary
Concomitant

Drug Data