Bisoprolol combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Life Threatening 9/2/2003 Male 1/4/2006 Finland
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/20/2002 Female 1/4/2006 Finland
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/6/2005 81 Male 154 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Surgery Hospitalization 4/12/2005 46 Male 192 lb 1/4/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 67 Female 2/9/2006 Consumer United Kingdom
Primary
Secondary
Parkinsonism Hospitalization 9/5/2005 52 Male 2/6/2006 Germany
Primary
Secondary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/6/2005 81 Male 154 lb 2/15/2006 Poland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/16/2006 Poland
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 5/9/2005 77 Male 220 lb 2/21/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 5/9/2005 77 Male 220 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Shock Hospitalization 67 Female 3/10/2006 Consumer United Kingdom
Primary
Secondary
Skin Cancer Life Threatening 5/9/2005 77 Male 220 lb 3/10/2006 Poland
Primary
Secondary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/15/2006 Singapore
Primary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/22/2006 Physician Singapore
Primary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/21/2006 Physician Singapore
Primary
Concomitant
Myocardial Infarction Other Serious 4/17/2006 71 Female 141 lb 6/1/2006 Physician United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 11/19/2005 78 Male 196 lb 6/13/2006 United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 73 Male 6/7/2006 Other Health Professional France
Primary
Secondary
Haematuria Hospitalization 9/2/2006 86 Male 1/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Shock Hospitalization 67 Female 3/12/2007 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 3/7/2007 72 Male 4/4/2007 Physician United Kingdom
Primary
Concomitant
Convulsion Hospitalization 5/22/2007 78 Male 7/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lipids Abnormal Other Serious 6/1/2007 70 Female 121 lb 7/19/2007 Pharmacist United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 67 Female 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/25/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Convulsion Other Serious 5/22/2007 78 Male 12/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 3/7/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/1/2008 75 Male 161 lb 8/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 9/29/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 44 Male 362 lb 2/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2008 43 Female 362 lb 3/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Life Threatening 3/6/2008 77 Male 176 lb 3/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 5/22/2008 50 Male 3/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 5/1/2007 43 Female 362 lb 3/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 5/22/2008 50 Male 196 lb 3/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspepsia Hospitalization 10/10/2008 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 44 Male 360 lb 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 44 Male 360 lb 3/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 43 Female 362 lb 3/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/13/2008 44 Male 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious Male 218 lb 3/24/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 3/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 86 Female 4/20/2009 Physician Finland
Primary
Secondary
Concomitant
Bacterial Infection Hospitalization 3/6/2009 Female 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 86 Female 5/1/2009 Physician Finland
Primary
Secondary
Concomitant
Syncope Death 1/6/2009 79 Female 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 86 Female 5/13/2009 Physician Finland
Primary
Secondary
Concomitant
Supraventricular Tachyarrhythmia Life Threatening 3/26/2009 Male 5/15/2009 Consumer United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/26/2009 Male 5/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Bronchitis Hospitalization 3/29/2007 77 5/25/2009 Physician Poland
Primary
Secondary
Concomitant
Palpitations Hospitalization 5/26/2009 69 6/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/27/2009 74 Male 157 lb 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Increased Hospitalization 10/10/2008 43 Female 362 lb 7/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 7/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 362 lb 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 6/10/2009 59 Male 8/5/2009 Other Health Professional Denmark
Primary
Concomitant
Pruritus 1/1/2003 Male 165 lb 8/22/2009 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Death 78 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 82 Female 9/30/2009 United Kingdom
Primary
Concomitant
Troponin Increased Other Serious 10/1/2008 Female 154 lb 10/12/2009 Consumer Ireland
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 43 Female 362 lb 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 10/23/2009 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 10/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 10/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/2/2009 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/4/2009
Primary
Secondary
Concomitant
Dyspnoea Other Serious 6/10/2009 59 Male 11/4/2009 Other Health Professional Denmark
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 43 Female 362 lb 11/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/10/2009
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 359 lb 11/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 11/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 360 lb 11/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Other Serious 8/24/2007 Female 157 lb 12/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Malignant Tumour Excision Other Serious 1/11/2010 65 Female 145 lb 3/15/2010 United Kingdom
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 1/29/2010 Male 134 lb 3/22/2010 Physician Bulgaria
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 1/11/2010 65 Female 3/18/2010 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/23/2010 58 Male 266 lb 4/1/2010 Physician United Kingdom
Primary
Concomitant
Thrombosis In Device Life Threatening 1/29/2010 44 Male 134 lb 4/1/2010 Physician Bulgaria
Primary
Concomitant
Rash Pruritic Other Serious 8/15/2008 63 Male 171 lb 5/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Other Serious 6/30/2009 63 Male 171 lb 5/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pelvic Fracture Hospitalization 9/11/2009 81 Female 5/18/2010 Physician United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 61 Male 5/26/2010 Other Health Professional Poland
Primary
Secondary
International Normalised Ratio Increased Hospitalization 5/7/2010 75 Male 6/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 11/19/2005 78 Male 196 lb 6/24/2010 United Kingdom
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 9/11/2009 81 Female 6/29/2010 Physician United Kingdom
Primary
Concomitant
Sensitivity Of Teeth 9/1/2006 50 Female 260 lb 7/8/2010 Consumer United States
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 3/17/2010 41 Male 273 lb 7/21/2010 Physician Denmark
Primary
Concomitant
Vomiting Hospitalization 3/12/2010 83 Male 181 lb 7/30/2010 Physician Canada
Primary
Concomitant
Intentional Drug Misuse Death 2/10/2010 76 Female 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Cancer Hospitalization 8/17/2010 60 Male 154 lb 9/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ischaemia Hospitalization 8/17/2010 60 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ischaemia Other Serious 60 Male 9/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 9/30/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Chills Other Serious 71 Female 10/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Diverticulitis Disability 1/1/2007 66 Female 120 lb 10/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Other Serious 5/1/2009 Female 10/28/2010 Other Health Professional Switzerland
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 11/1/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Syncope Hospitalization 57 Female 11/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 57 Female 11/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 3/6/2008 77 Male 176 lb 11/16/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Pneumonia Disability 1/1/2010 87 Female 119 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 71 Female 117 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 12/21/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 10/1/2007 68 Male 12/27/2010 Australia
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 12/29/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 9/1/2010 56 Male 212 lb 1/4/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/5/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 1/9/2011 77 Male 191 lb 1/13/2011 Physician Spain
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/1/2010 85 Male 1/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization 12/28/2010 77 Male 191 lb 1/20/2011 Physician Spain
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 12/31/2010 77 Male 191 lb 1/21/2011 Physician Spain
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 1/24/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious Male 1/24/2011 Physician Switzerland
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2010 87 Female 119 lb 1/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Condition Aggravated Other Serious 12/31/2010 77 Male 191 lb 2/1/2011 Physician Spain
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 2/7/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Clostridial Infection Death 88 Female 2/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ischaemic Stroke Other Serious 7/18/2010 88 Male 2/8/2011 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Death 10/22/2009 88 Female 2/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Death 88 Female 2/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Pressure Decreased Death 88 Female 2/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Asthenia Death 88 Female 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Culture Positive Hospitalization 11/27/2009 90 3/15/2011 Physician Switzerland
Primary
Concomitant
Ventricular Fibrillation Life Threatening 71 Male 3/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 1/13/2011 76 Male 3/9/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Epistaxis Other Serious 76 Female 3/14/2011 Other Health Professional
Primary
Concomitant
Hepatotoxicity Hospitalization 61 Male 236 lb 3/30/2011 Other Health Professional Poland
Primary
Concomitant
Myocardial Infarction Hospitalization 2/6/2011 84 Female 4/7/2011 Consumer Switzerland
Primary
Concomitant
Myocardial Ischaemia Death 11/20/2009 90 101 lb 4/8/2011 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 1/13/2011 76 Male 4/4/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Atrioventricular Block Life Threatening 51 Male 4/27/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 51 Male 4/27/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 51 Male 4/27/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Hypotension Other Serious 8/20/2010 73 Male 4/28/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Atrioventricular Block Hospitalization 51 Male 6/1/2011 Physician Poland
Primary
Concomitant

Drug Data