Bisoprolol Fumarate combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Death 9/5/2005 33 Male 2/13/2006 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization Female 2/16/2006 Ireland
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/16/2006 Physician Canada
Primary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/17/2006 Physician Canada
Primary
Concomitant
Overdose Hospitalization 1/23/2006 28 Female 3/2/2006 France
Primary
Secondary
Concomitant
Lethargy Other Serious 2/10/2006 75 Male 3/28/2006 United Kingdom
Primary
Concomitant
Parkinsonism Disability 1/1/2004 65 Female 4/10/2006 Pharmacist Ireland
Primary
Concomitant
Tremor Disability 1/1/2004 65 Female 5/3/2006 Other Health Professional Denmark
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 9/3/2005 46 Male 5/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 1/30/2006 78 Female 6/19/2006 Canada
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 2/23/2006 77 Female 6/23/2006 Physician United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 2/23/2006 77 Female 6/27/2006 Physician United Kingdom
Primary
Concomitant
Wound Secretion Other Serious 6/2/2006 67 Male 7/12/2006 Other Health Professional Ireland
Primary
Concomitant
Angioneurotic Oedema Other Serious 74 Male 7/13/2006 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 2/24/2006 Female 7/19/2006 Physician Belgium
Primary
Concomitant
Syncope Other Serious 4/27/2006 71 Female 139 lb 7/14/2006 Physician Portugal
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Wound Secretion Other Serious 6/2/2006 67 Male 7/27/2006 Other Health Professional Ireland
Primary
Concomitant
Syncope Hospitalization 1/23/2006 58 Female 8/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Required Intervention 7/30/2006 76 Female 118 lb 8/6/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2002 57 Male 8/8/2006 Other Health Professional Japan
Primary
Concomitant
Wound Secretion Other Serious 6/2/2006 67 Male 8/24/2006 Other Health Professional Ireland
Primary
Concomitant
Blood Amylase Increased Other Serious 5/1/2005 78 Male 9/5/2006 United Kingdom
Primary
Concomitant
Platelet Count Decreased Disability 58 Male 9/12/2006 Physician United States
Primary
Secondary
Concomitant
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/4/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/10/2006 Physician
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 10/16/2006 Physician
Primary
Secondary
Concomitant
Rash Other Serious 80 Female 137 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/12/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/19/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 10/23/2006 Physician
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphocyte Percentage Decreased Hospitalization 10/2/2006 66 Female 11/10/2006 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Pleural Effusion Death 9/29/2006 81 Female 143 lb 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Extraction Disability 4/4/2004 81 Male 12/19/2006 Physician Ireland
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 70 Male 12/14/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2006 Female 1/5/2007 Physician Fiji
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Life Threatening 7/12/2001 Female 1/8/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2006 Female 1/17/2007 Physician Fiji
Primary
Secondary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Small Intestine Carcinoma Metastatic Death 3/2/2006 82 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Life Threatening 7/12/2001 Female 2/19/2007 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 8/15/2006 Female 3/21/2007 Pharmacist Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/1/2006 46 Male 344 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Pruritus Hospitalization 4/1/2006 84 Male 5/3/2007 Other Health Professional France
Primary
Secondary
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization 10/4/2006 Female 5/15/2007 Physician Belgium
Primary
Concomitant
Renal Failure Hospitalization 5/7/2007 79 Male 5/24/2007 Other Health Professional Italy
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/29/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Increased Upper Airway Secretion Other Serious 1/1/2007 Male 195 lb 6/1/2007 Physician United States
Primary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 10/4/2006 Female 6/18/2007 Physician Belgium
Primary
Concomitant
Pyrexia Other Serious 3/23/2007 72 Male 6/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sensory Loss Other Serious 58 Male 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 74 Male 7/11/2007 United Kingdom
Primary
Concomitant
Death Death 7/4/2007 Male 137 lb 7/23/2007 Physician United Kingdom
Primary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 7/6/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 8/3/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 76 Male 8/3/2007 Finland
Primary
Secondary
Concomitant
Melaena Death 74 Male 7/13/2007 United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 58 Male 9/7/2007 United Kingdom
Primary
Secondary
Concomitant
Metastases To Bone Hospitalization 8/27/2007 56 Female 128 lb 9/7/2007 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 58 Male 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Recurrent Hospitalization 8/27/2007 56 Female 128 lb 9/20/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 10/30/2006 54 Male 115 lb 10/4/2007 Physician Japan
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 58 Male 10/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 10/3/2007 United Kingdom
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 Male 281 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/17/2007 75 Female 194 lb 10/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 9/6/2007 64 Female 170 lb 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 58 Male 10/15/2007 United Kingdom
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 72 Male 10/18/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 73 Male 10/22/2007 Consumer United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/23/2007 67 Male 223 lb 10/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 10/24/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 73 Male 10/19/2007 United Kingdom
Primary
Concomitant
Pain 1/1/2002 54 Male 10/24/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/27/2007 10/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Iris Cyst Other Serious 75 Female 10/30/2007 United Kingdom
Primary
Concomitant
Breast Cancer Recurrent Hospitalization 8/27/2007 Female 128 lb 10/25/2007 Physician Japan
Primary
Concomitant
Iris Cyst Other Serious 75 Female 11/12/2007 United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 10/11/2007 81 Female 11/8/2007 Japan
Primary
Secondary
Pulmonary Hypertension Other Serious 60 Female 11/14/2007 Consumer United Kingdom
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/17/2007 75 Female 194 lb 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 74 Male 11/19/2007 United Kingdom
Primary
Concomitant
Peripheral Motor Neuropathy Other Serious Female 12/10/2007 South Africa
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/1/2002 Male 1/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/19/2007 71 Female 220 lb 1/21/2008 Consumer United Kingdom
Primary
Concomitant
Death Death 78 Male 165 lb 1/28/2008 Pharmacist United Kingdom
Primary
Concomitant
Peripheral Motor Neuropathy Other Serious Female 1/24/2008 South Africa
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Polymyositis Hospitalization 12/1/2006 77 Male 2/18/2008 Other Health Professional Norway
Primary
Concomitant
Myocardial Infarction Other Serious 12/19/2007 71 Female 220 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2007 79 Male 2/13/2008 Other Health Professional Israel
Primary
Concomitant
Syncope Life Threatening 2/4/2008 63 Male 165 lb 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Death 2/4/2008 63 Male 165 lb 2/25/2008 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/19/2007 71 Female 220 lb 3/4/2008 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/11/2007 81 Female 3/3/2008 Japan
Primary
Secondary
Concomitant
Syncope Life Threatening 2/4/2008 63 Male 2/29/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/11/2007 94 Female 99 lb 3/7/2008 Other Health Professional
Primary
Concomitant
Renal Failure Hospitalization 3/2/2008 74 Male 4/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 1/20/2008 85 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Cancer Other Serious 65 Female 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 4/22/2008 Physician Canada
Primary
Concomitant
Drug Level Below Therapeutic Other Serious 1/1/2008 61 Male 4/25/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/1/2002 Male 5/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 4/18/2008 Male 158 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 5/13/2008 Physician Canada
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/1/2002 Male 5/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/25/2008 74 Male 5/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bile Duct Cancer Life Threatening 70 Female 143 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Bile Duct Cancer Life Threatening 70 Female 5/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 4/29/2008 5/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 143 lb 5/16/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 4/29/2008 60 Female 243 lb 6/3/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Shock Disability 4/15/2008 74 Male 5/27/2008 Other Health Professional Japan
Primary
Concomitant
Syncope Other Serious 83 Female 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 4/29/2008 60 Female 6/2/2008 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 4/29/2008 60 Female 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2007 Female 167 lb 6/12/2008 Consumer United Kingdom
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Syncope Other Serious 83 Female 6/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 83 Female 143 lb 6/10/2008
Primary
Secondary
Concomitant
Vomiting Other Serious 5/8/2008 76 Female 121 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Radius Fracture Hospitalization 12/10/2007 Female 135 lb 6/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/12/2006 45 Male 6/5/2008 United Kingdom
Primary
Secondary
Renal Failure Hospitalization 1/1/2004 58 Male 6/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 5/22/2003 Male 7/7/2008 Other Health Professional Sweden
Primary
Concomitant
Interacting
Headache Other Serious Female 210 lb 7/7/2008 Consumer United States
Primary
Concomitant
Iris Cyst Other Serious 75 Female 7/22/2008 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Death 27 Female 7/4/2008 United Kingdom
Primary
Concomitant
Iris Cyst Other Serious 75 Female 7/29/2008 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 84 Female 7/29/2008 United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 27 Female 7/21/2008 United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 7/18/2008 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 7/3/2008 80 Male 8/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 12/11/2007 94 Female 99 lb 8/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Other Serious 48 Male 8/27/2008 United States
Primary
Concomitant

Drug Data