Bisoprolol Fumarate combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/12/2006 Male 154 lb 9/21/2006 Physician France
Primary
Concomitant
Vomiting Other Serious 9/17/2006 68 Male 9/27/2006 Pharmacist Canada
Primary
Concomitant
Respiratory Failure Other Serious 9/11/2006 72 Female 10/5/2006 Pharmacist Ireland
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Subdural Haematoma Hospitalization 3/1/2006 Female 140 lb 10/27/2006 Consumer United States
Primary
Concomitant
Somnolence 10/1/2005 69 Female 10/30/2006 Consumer United States
Primary
Concomitant
Respiratory Disorder Hospitalization 11/6/2006 69 Male 11/28/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 11/6/2006 69 Male 11/30/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 9/17/2006 68 Male 1/15/2007 Pharmacist Canada
Primary
Concomitant
Respiratory Disorder Hospitalization 11/6/2006 69 Male 1/22/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oxygen Consumption Decreased 5/1/2005 Male 2/22/2007 United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/16/2007 72 Male 8/31/2007 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/16/2007 72 Male 9/28/2007 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 72 Male 9/27/2007 Consumer United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 Male 172 lb 10/15/2007 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 7/9/2007 70 Male 196 lb 11/5/2007 Physician Australia
Primary
Secondary
Concomitant
Respiratory Arrest Death 7/3/2007 43 Male 1/3/2008 Other Health Professional Australia
Primary
Secondary
Non-small Cell Lung Cancer Hospitalization 7/20/2007 61 Male 2/29/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/31/2007 59 Male 2/28/2008 France
Primary
Secondary
Throat Tightness 1/10/2008 Female 4/10/2008 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 3/31/2008 64 Male 5/13/2008 Physician
Primary
Concomitant
Superinfection Hospitalization 4/1/2008 98 Male 5/26/2008 France
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/31/2007 60 Male 7/11/2008 Other Health Professional France
Primary
Concomitant
Pleuritic Pain Hospitalization 7/24/2007 70 Male 196 lb 7/16/2008 Physician Australia
Primary
Secondary
Concomitant
Nausea Other Serious 4/17/2008 66 Female 7/16/2008 Consumer Canada
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 8/6/2008 Male 170 lb 9/2/2008 Physician Germany
Primary
Secondary
Concomitant
Vasculitis Other Serious 9/13/2008 Female 11/18/2008 Physician
Primary
Secondary
Concomitant
Nausea Other Serious 4/17/2008 Female 105 lb 11/26/2008 Physician Canada
Primary
Concomitant
Dry Mouth Other Serious 6/1/2008 76 Male 12/1/2008 Physician Germany
Primary
Concomitant
Hyponatraemia Hospitalization 9/1/2008 74 Male 12/9/2008 France
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 6/7/2006 Male 12/19/2008 Physician
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/6/2008 82 Male 1/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 3/9/2009 Pharmacist Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 54 Male 172 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 3/9/2009 3/27/2009 Physician Sweden
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/29/2008 Female 5/1/2009 Physician Canada
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/6/2009 Male 164 lb 7/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/31/2009 57 10/14/2009 Physician Belgium
Primary
Concomitant
Thrombocytopenia Hospitalization 7/31/2009 57 10/22/2009 Physician Belgium
Primary
Concomitant
Thrombocytopenia Hospitalization 7/31/2009 57 Female 141 lb 2/15/2010 Physician Belgium
Primary
Concomitant
Hyponatraemia Hospitalization 9/1/2008 Male 3/9/2010 Other Health Professional
Primary
Concomitant
Thrombocytopenia Hospitalization 8/8/2008 70 Male 3/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 8/16/2008 54 Male 172 lb 5/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Benign Prostatic Hyperplasia Other Serious 4/23/2010 59 Male 165 lb 5/5/2010 Consumer Canada
Primary
Concomitant
Malaise Hospitalization 3/8/2010 72 Male 5/21/2010 Other Health Professional France
Primary
Concomitant
Osteoporotic Fracture Hospitalization 5/26/2010 81 Female 198 lb 6/30/2010
Primary
Concomitant
Pneumonia Death 6/6/2010 6/30/2010 Physician Canada
Primary
Concomitant
Renal Failure Hospitalization 7/8/2010 80 Male 8/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization Female 8/16/2010 Physician Italy
Primary
Secondary
Concomitant
Weight Increased Life Threatening Male 8/31/2010 Physician Netherlands
Primary
Concomitant
Sudden Death Death 5/7/2009 61 Male 168 lb 9/3/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Sudden Death Death 5/7/2009 61 Male 168 lb 9/3/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/8/2010 Physician Germany
Primary
Concomitant
Off Label Use Life Threatening 10/10/2010 69 Female 181 lb 11/18/2010 Physician Germany
Primary
Concomitant
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 11/26/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 11/26/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Thrombocytopenia Hospitalization 7/31/2009 57 Female 141 lb 12/2/2010 Physician Belgium
Primary
Concomitant
Muscle Spasms Hospitalization 4/1/2010 63 Female 2/2/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 3/2/2011 Physician Netherlands
Primary
Concomitant
Renal Cancer Hospitalization 11/1/2010 64 Male 3/7/2011 Physician United Kingdom
Primary
Concomitant
Injection Site Pain Hospitalization 4/1/2010 63 Female 4/4/2011 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 12/20/2010 81 Male 4/26/2011 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 5/18/2011 Physician Germany
Primary
Concomitant
Pancytopenia Hospitalization 5/5/2011 67 Male 183 lb 5/17/2011 Physician Germany
Primary
Secondary
Concomitant
Blister Hospitalization 11/4/2010 71 Female 202 lb 5/19/2011 Other Health Professional Austria
Primary
Concomitant
Erythema Hospitalization 11/1/2010 73 Male 194 lb 5/25/2011 Physician Germany
Primary
Concomitant
Dyspepsia Hospitalization 4/2/2011 78 Male 125 lb 6/6/2011 Physician Japan
Primary
Concomitant
Muscle Spasms Hospitalization 4/1/2010 63 Female 6/17/2011 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 4/2/2011 78 Male 125 lb 6/22/2011 Physician Japan
Primary
Concomitant
Infection Hospitalization 1/1/2011 68 Male 237 lb 6/29/2011 Physician United States
Primary
Concomitant
Acute Psychosis Other Serious 3/12/2011 83 Male 179 lb 7/27/2011 Physician Austria
Primary
Concomitant
Anaemia Hospitalization 11/16/2009 49 Male 8/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Leukopenia Death 11/16/2009 49 Male 163 lb 8/17/2011 Physician Hungary
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 11/23/2007 68 Male 8/18/2011 Other Health Professional Sweden
Primary
Concomitant
Ventricular Extrasystoles Other Serious 11/3/2010 63 Male 159 lb 8/19/2011 Physician Germany
Primary
Secondary
Concomitant
Granulocytopenia Death 11/16/2009 49 Male 163 lb 8/22/2011 Physician Hungary
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 8/26/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 7/6/2011 83 Male 8/29/2011 Other Health Professional France
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 8/24/2011 Male 8/30/2011 Physician Germany
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Hospitalization 7/6/2011 83 Male 8/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Arthralgia Other Serious 8/8/2011 75 Female 132 lb 9/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Eye Swelling Other Serious 1/1/2011 73 Female 187 lb 9/7/2011 Physician Germany
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 1/1/2011 75 Male 137 lb 9/2/2011 Other Health Professional Germany
Primary
Concomitant
Overdose Hospitalization 8/19/2011 74 Male 9/7/2011 Other Health Professional
Primary
Secondary
Concomitant
Granulocytopenia Death 11/16/2009 49 Male 9/12/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Cough Hospitalization 8/19/2011 74 Male 9/9/2011 Other Health Professional
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease 6/23/2011 82 Male 238 lb 9/21/2011 Physician Australia
Primary
Concomitant
Renal Failure Hospitalization 6/11/2011 66 Female 10/10/2011 Physician Norway
Primary
Concomitant
Drug Ineffective 3/10/2011 71 Female 10/24/2011 Consumer United States
Primary
Concomitant
Thrombophlebitis Hospitalization 3/19/2011 79 Female 11/18/2011 Consumer Canada
Primary
Concomitant
Lung Neoplasm Other Serious Female 11/25/2011 Consumer Canada
Primary
Concomitant
Treatment Noncompliance Hospitalization 8/19/2011 74 Male 11/22/2011 Other Health Professional
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 10/1/2011 85 Male 12/5/2011 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 10/14/2011 88 Female 106 lb 12/9/2011 Physician Spain
Primary
Concomitant
Hypercapnia Life Threatening 6/16/2008 71 Male 230 lb 12/5/2011 Lawyer United States
Primary
Concomitant
Bone Disorder Other Serious 4/1/2010 63 Female 12/21/2011 Consumer United States
Primary
Concomitant
Erythema Nodosum Hospitalization 10/1/2011 72 Male 1/5/2012 Other Health Professional France
Primary
Secondary
Concomitant
Diarrhoea Disability 12/13/2011 89 Female 140 lb 1/3/2012 Other Health Professional
Primary
Concomitant
Diarrhoea Disability 12/13/2011 89 Female 140 lb 1/4/2012 Other Health Professional
Primary
Concomitant
Wheezing Disability 12/13/2011 89 Female 140 lb 1/12/2012 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Hospitalization 12/16/2011 68 Female 1/13/2012 Physician Italy
Primary
Concomitant
General Physical Health Deterioration Disability 1/1/2011 72 Female 141 lb 1/13/2012 Physician Germany
Primary
Concomitant
Interacting
Epistaxis Death 12/19/2011 77 Male 172 lb 1/13/2012 Germany
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 10/13/2011 77 Male 1/17/2012 Other Health Professional Finland
Primary
Concomitant
Pneumonia Bacterial Other Serious 11/26/2009 55 Male 90 lb 1/17/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 11/26/2009 55 Male 90 lb 1/25/2012 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 8/16/2008 54 Male 172 lb 1/25/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 10/14/2011 88 Female 106 lb 1/26/2012 Physician Spain
Primary
Concomitant
Skin Wrinkling Hospitalization 10/31/2008 75 Female 1/27/2012 Other Health Professional France
Primary
Secondary
Food Intolerance Hospitalization 10/31/2008 75 Female 1/27/2012 Other Health Professional France
Primary
Secondary
Death Hospitalization 12/8/2010 65 Female 142 lb 1/26/2012 Consumer Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/5/2011 67 Male 183 lb 1/26/2012 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Other Serious Male 176 lb 1/27/2012 Other Health Professional Germany
Primary
Concomitant
Haematoma Hospitalization 1/8/2012 69 Female 165 lb 1/30/2012 Physician Austria
Primary
Secondary
Haematoma Hospitalization 1/8/2012 69 Female 165 lb 2/6/2012 Physician Austria
Primary
Secondary
Renal Failure Other Serious 7/8/2010 80 Male 2/7/2012 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/31/2008 75 Female 2/8/2012 Other Health Professional France
Primary
Secondary
Hypotension Hospitalization 1/16/2012 87 Female 2/13/2012 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/21/2011 59 Female 2/14/2012 Consumer United States
Primary
Secondary
Concomitant
Yellow Skin Hospitalization 73 Male 185 lb 2/21/2012 Pharmacist Canada
Primary
Concomitant
Hypotension Hospitalization 1/16/2012 87 Female 2/22/2012 Physician Italy
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/16/2012 87 Female 2/24/2012 Physician Italy
Primary
Secondary
Concomitant
Haematoma Hospitalization 1/1/2011 64 Female 165 lb 2/26/2012 Consumer Austria
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 7/31/2010 73 Male 2/26/2012 Physician France
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 10/13/2011 72 Male 2/17/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 61 Female 2/27/2012 Pharmacist Canada
Primary
Secondary
Traumatic Haematoma Other Serious 1/1/2012 70 Female 2/27/2012 Physician Germany
Primary
Concomitant
Asthenia Hospitalization Male 2/27/2012 Physician Hungary
Primary
Concomitant
Bronchitis Chronic Hospitalization Female 2/29/2012 Physician Belgium
Primary
Concomitant
Bronchitis Chronic Hospitalization Female 3/2/2012 Physician Belgium
Primary
Concomitant
Blood Glucose Decreased Other Serious 12/24/2011 67 Female 3/2/2012 Physician Canada
Primary
Concomitant
Asthenia Hospitalization Male 3/5/2012 Physician Hungary
Primary
Concomitant
Hypotension Hospitalization 1/16/2012 87 Female 3/5/2012 Physician Italy
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 1/1/2007 85 Male 161 lb 3/6/2012 Physician Canada
Primary
Concomitant
Skin Mass Other Serious Female 3/7/2012 Consumer Ireland
Primary
Concomitant
Pyrexia Other Serious 11/26/2009 55 Male 90 lb 3/14/2012 Physician Japan
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 6/16/2009 51 Female 3/15/2012 Physician Belgium
Primary
Concomitant
Pyrexia Other Serious 11/26/2009 55 Male 90 lb 3/20/2012 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious Female 3/22/2012 Consumer Slovenia
Primary
Concomitant
Rales Death 10/19/2011 89 Male 161 lb 3/26/2012 Physician Canada
Primary
Concomitant
Administration Site Reaction Hospitalization 3/14/2012 78 Female 93 lb 3/29/2012 Physician Poland
Primary
Concomitant
Pneumonia Bacterial Hospitalization 11/26/2009 55 Male 90 lb 4/3/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 9/1/2011 66 Male 165 lb 4/3/2012 Other Health Professional Denmark
Primary
Concomitant
Hyponatraemia Other Serious Female 4/4/2012 Physician Slovenia
Primary
Secondary
Concomitant
Tremor Other Serious 11/5/2011 76 Male 154 lb 4/10/2012 Germany
Primary
Concomitant
Pericardial Effusion Hospitalization 10/12/2010 52 Male 166 lb 4/9/2012 Physician Hungary
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/23/2012 67 Male 4/20/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data