Bisoprolol Fumarate combined with Rabeprazole Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 3/14/2006 Other Health Professional Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/17/2006 Physician Austria
Primary
Secondary
Concomitant
Visual Acuity Reduced Life Threatening 1/10/2006 Female 146 lb 9/7/2006 Physician Germany
Primary
Concomitant
Lethargy Other Serious 8/3/2006 72 Male 172 lb 9/28/2006 Consumer United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 90 Female 10/18/2006 Other Health Professional France
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/29/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Transaminases Increased Hospitalization 10/4/2005 85 Male 6/1/2007 Physician France
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 8/3/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Visual Acuity Reduced Other Serious Female 10/19/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/3/2007 Female 136 lb 10/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious 2/7/2006 73 Male 10/25/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/3/2007 Female 136 lb 10/31/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Ocular Hyperaemia Disability 2/7/2007 73 Male 10/26/2007 United Kingdom
Primary
Concomitant
Oedema Hospitalization 1/1/2008 70 Male 121 lb 6/2/2008 Physician Italy
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/6/2008 Female 132 lb 9/2/2008 France
Primary
Concomitant
Pyelonephritis Other Serious 8/6/2008 Female 132 lb 9/26/2008 France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Gynaecomastia 10/20/2008 73 Male 2/10/2009 Other Health Professional France
Primary
Concomitant
Gynaecomastia 10/20/2008 73 Male 4/16/2009 France
Primary
Concomitant
Bile Duct Stone Hospitalization 6/19/2009 71 Female 11/25/2009 Japan
Primary
Concomitant
Pneumonia Death 6/6/2010 6/30/2010 Physician Canada
Primary
Concomitant
Thyroiditis Other Serious 80 Male 8/9/2010 Other Health Professional Ireland
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2009 75 Female 143 lb 9/14/2010 Other Health Professional France
Primary
Secondary
Vulvovaginal Burning Sensation Hospitalization 3/1/2010 76 Female 9/2/2010 France
Primary
Secondary
Weight Decreased Hospitalization 3/1/2010 76 Male 9/2/2010 France
Primary
Secondary
Thyroid Neoplasm Hospitalization 4/21/2010 56 Female 170 lb 3/8/2011 Physician Hungary
Primary
Secondary
Concomitant
Coordination Abnormal Life Threatening 91 Female 5/12/2011 Physician Canada
Primary
Concomitant
Muscle Contracture Life Threatening 91 Female 5/12/2011 Physician Canada
Primary
Concomitant
Asthenia Other Serious 12/8/2010 72 Female 106 lb 5/12/2011 Other Health Professional France
Primary
Concomitant
Abdominal Pain Upper Life Threatening 3/30/2011 79 Male 128 lb 5/13/2011 Physician Japan
Primary
Concomitant
Regurgitation Other Serious 3/30/2011 79 Male 128 lb 5/26/2011 Physician Japan
Primary
Concomitant
Jaundice Death 1/30/2011 75 Male 5/27/2011 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/24/2011 84 Female 6/2/2011 Other Health Professional France
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 3/8/2011 77 Female 6/3/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Hepatic Failure Death 1/30/2011 75 Male 146 lb 6/3/2011 Other Health Professional France
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 4/2/2011 78 Male 125 lb 6/6/2011 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 1/17/2011 84 Female 6/9/2011 Other Health Professional France
Primary
Concomitant
Interacting
Dysphonia Other Serious 1/1/2004 72 Female 6/11/2011 Colombia
Primary
Concomitant
Cystitis Hospitalization 10/20/2010 65 Female 6/16/2011 Physician Austria
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 4/2/2011 78 Male 125 lb 6/22/2011 Physician Japan
Primary
Concomitant
Gastroenteritis Escherichia Coli Hospitalization 10/20/2010 65 Female 6/23/2011 Physician Austria
Primary
Secondary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 10/1/2010 71 Male 115 lb 7/6/2011 Physician Japan
Primary
Concomitant
Multiple Myeloma Death 5/2/2011 76 Female 108 lb 7/7/2011 Physician France
Primary
Concomitant
Haematuria Hospitalization 6/21/2011 74 Female 154 lb 7/15/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 4/1/2011 76 Female 108 lb 8/3/2011 Other Health Professional France
Primary
Concomitant
Multiple Myeloma Hospitalization 4/1/2011 76 Female 108 lb 8/11/2011 Other Health Professional France
Primary
Concomitant
Thyroid Neoplasm Hospitalization 4/21/2010 56 Female 170 lb 8/17/2011 Physician Hungary
Primary
Secondary
Concomitant
Pancreatolithiasis Other Serious 5/1/2009 56 Male 148 lb 8/19/2011 Other Health Professional France
Primary
Concomitant
Hyperamylasaemia Other Serious 2/24/2007 58 Female 93 lb 8/22/2011 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/12/2011 78 Male 8/24/2011 Physician Japan
Primary
Concomitant
Activated Partial Thromboplastin Time Prolonged Other Serious 6/21/2011 94 Female 8/25/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 5/1/2011 81 Female 8/26/2011 Physician Canada
Primary
Concomitant
Respiratory Distress Hospitalization 5/1/2011 81 Female 8/29/2011 Physician Canada
Primary
Concomitant
Overdose Hospitalization 3/14/2011 79 Female 8/12/2011 Other Health Professional France
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 4/29/2011 68 Female 190 lb 9/6/2011 Consumer Canada
Primary
Concomitant
Activated Partial Thromboplastin Time Prolonged 6/21/2011 94 Female 9/8/2011 Physician Japan
Primary
Concomitant
Tachyarrhythmia Other Serious 7/12/2011 77 Female 9/12/2011 Other Health Professional France
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 6/21/2011 74 Female 154 lb 9/12/2011 Physician Japan
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 10/1/2010 71 Male 115 lb 9/12/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 12/6/2010 52 Male 137 lb 9/12/2011 Physician Japan
Primary
Concomitant
Bacterial Test Positive Hospitalization 8/20/2011 79 Male 134 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/12/2011 78 Male 183 lb 9/13/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 1/1/2011 84 Female 9/15/2011 Other Health Professional France
Primary
Concomitant
Interacting
Constipation Life Threatening 9/13/2010 56 Male 126 lb 9/19/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Death 9/12/2011 85 Female 9/19/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 1/1/2011 84 Female 9/19/2011 Other Health Professional France
Primary
Concomitant
Interacting
Diarrhoea Life Threatening 9/12/2011 85 Female 9/22/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Life Threatening 12/28/2010 70 Male 140 lb 9/28/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/20/2011 79 Male 134 lb 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Overdose Hospitalization 6/19/2011 77 Female 9/27/2011 Physician France
Primary
Concomitant
Diarrhoea Hospitalization 9/12/2011 85 Female 10/4/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 10/12/2011 Physician Japan
Primary
Secondary
Concomitant
Haematoma Hospitalization 8/15/2011 84 Male 10/17/2011 Consumer France
Primary
Secondary
Concomitant
Fall Hospitalization 8/15/2011 84 Male 10/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 9/24/2011 77 Female 10/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Other Serious 9/22/2011 77 Female 10/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Chest Discomfort Life Threatening 9/24/2011 77 Female 10/21/2011 Physician France
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 7/4/2008 58 Female 10/24/2011 Physician Japan
Primary
Concomitant
Gaze Palsy Hospitalization 4/17/2009 74 Male 123 lb 11/2/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/1/2010 68 Male 11/8/2011 Physician Japan
Primary
Concomitant
Gaze Palsy Hospitalization 4/17/2009 74 Male 123 lb 11/10/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 12/1/2010 68 Male 11/13/2011 Japan
Primary
Concomitant
Thyroid Neoplasm Hospitalization 4/21/2010 56 Female 170 lb 11/22/2011 Physician Hungary
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/1/2010 68 Male 11/23/2011 Physician Japan
Primary
Secondary
Concomitant
Refractory Anaemia Hospitalization 10/22/2011 83 Female 11/25/2011 Physician France
Primary
Concomitant
Chronic Myeloid Leukaemia Transformation Death 1/6/2010 77 Male 12/1/2011 Physician Japan
Primary
Concomitant
Aphasia Life Threatening 11/3/2011 73 Male 12/9/2011 Other Health Professional Australia
Primary
Concomitant
Pneumonia Hospitalization 12/1/2010 68 Male 12/21/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 10/12/2010 60 Male 128 lb 1/8/2012 Physician Japan
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 9/24/2011 77 Female 139 lb 1/11/2012 Physician France
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 9/22/2011 77 Female 138 lb 1/11/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/25/2011 68 Female 123 lb 1/23/2012 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 11/29/2011 75 Male 110 lb 1/24/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 4/17/2009 74 Male 123 lb 1/31/2012 Physician Japan
Primary
Concomitant
Haematoma Hospitalization 8/15/2011 84 Male 1/31/2012 Other Health Professional France
Primary
Secondary
Concomitant
Chills Other Serious 10/7/2011 73 Female 1/31/2012 Other Health Professional
Primary
Secondary
Concomitant
Blast Crisis In Myelogenous Leukaemia Death 1/6/2010 77 Male 2/8/2012 Physician Japan
Primary
Concomitant
Skin Disorder Hospitalization 86 Female 2/10/2012 Pharmacist Japan
Primary
Concomitant
Respiratory Disorder Hospitalization 86 Female 2/10/2012 Pharmacist Japan
Primary
Concomitant
Anaemia Hospitalization 12/1/2011 78 Female 3/1/2012 Consumer France
Primary
Secondary
Concomitant
Cerebral Infarction Disability 2/28/2012 78 Male 109 lb 3/12/2012 Physician Japan
Primary
Secondary
Hypoaesthesia Other Serious 3/18/2009 62 Male 134 lb 3/16/2012 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 2/28/2012 78 Male 109 lb 3/19/2012 Physician Japan
Primary
Secondary
Hypertension Other Serious 4/25/2011 75 Male 3/19/2012 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/26/2011 Female 90 lb 3/21/2012 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Death 12/9/2011 94 Male 3/23/2012 Physician France
Primary
Concomitant
Cerebrovascular Accident Disability 3/13/2012 73 Female 174 lb 3/27/2012 Physician Canada
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/24/2011 80 Female 187 lb 3/28/2012 Physician France
Primary
Concomitant
Interacting
Cerebral Infarction Hospitalization 2/28/2012 78 Male 109 lb 3/28/2012 Physician Japan
Primary
Secondary
Electrocardiogram Qt Prolonged Death 8/22/2011 60 Male 119 lb 3/29/2012 Physician Japan
Primary
Concomitant
Brain Death Death Male 154 lb 4/2/2012 Physician Japan
Primary
Concomitant
Cerebral Haematoma Life Threatening 85 Male 4/12/2012 Other Health Professional France
Primary
Secondary
Cerebral Haematoma Other Serious 85 Male 4/16/2012 Other Health Professional France
Primary
Secondary
Concomitant
Cerebrovascular Accident Disability 3/13/2012 73 Female 174 lb 4/18/2012 Physician Canada
Primary
Secondary
Concomitant
Haemorrhagic Transformation Stroke Disability 12/2/2011 68 Female 119 lb 4/23/2012 Physician Austria
Primary
Concomitant
Hepatitis B Hospitalization Female 179 lb 4/27/2012 Physician Hungary
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 4/2/2012 89 Male 141 lb 4/27/2012 Physician France
Primary
Concomitant
Kidney Infection Other Serious 1/1/2010 58 Female 4/27/2012 Consumer Canada
Primary
Concomitant
Organising Pneumonia Hospitalization 4/19/2012 75 Male 5/3/2012 Other Health Professional Canada
Primary
Concomitant
Serum Ferritin Increased Disability 6/12/2011 61 Female 5/3/2012 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 3/6/2012 58 Female 179 lb 5/3/2012 Physician Hungary
Primary
Secondary
Concomitant
Cellulitis Hospitalization 12/3/2011 58 Female 179 lb 5/7/2012 Physician Hungary
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 2/5/2012 81 Female 5/10/2012 Other Health Professional France
Primary
Concomitant
Interacting
Hyponatraemia Hospitalization 3/12/2012 Male 5/14/2012 Physician France
Primary
Concomitant
Hepatitis B Hospitalization 3/6/2012 58 Female 179 lb 5/18/2012 Physician Hungary
Primary
Secondary
Concomitant
Cellulitis Hospitalization 12/10/2011 58 Female 179 lb 5/18/2012 Physician Hungary
Primary
Secondary
Concomitant
Dysphonia Other Serious 4/25/2011 75 Male 5/18/2012 Physician Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 4/17/2012 75 Male 5/23/2012 Other Health Professional Canada
Primary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization Male 6/11/2012 Physician France
Primary
Concomitant
Interacting
Leukopenia Other Serious 5/2/2012 72 Male 6/12/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Tubular Atrophy Other Serious 8/1/2011 64 Male 6/13/2012 Physician France
Primary
Concomitant
Interacting
Sopor Hospitalization 4/5/2012 91 Female 6/18/2012 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/17/2012 72 Female 110 lb 6/21/2012 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 6/1/2012 74 Male 6/29/2012 Physician Canada
Primary
Concomitant
Arteriosclerosis Coronary Artery Hospitalization 6/28/2012 72 Male 176 lb 7/2/2012 Physician Italy
Primary
Concomitant
Basal Cell Carcinoma Other Serious 10/3/2011 73 Female 7/5/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Dizziness Postural 4/3/2009 62 Male 134 lb 7/11/2012 Physician Japan
Primary
Concomitant
Incorrect Route Of Drug Administration Hospitalization 6/1/2012 63 Male 243 lb 7/11/2012 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/17/2012 7/12/2012 Consumer Japan
Primary
Concomitant
Autoimmune Thrombocytopenia Hospitalization 6/13/2012 63 Male 243 lb 7/13/2012 Physician France
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 3/6/2012 58 Female 179 lb 7/13/2012 Physician Hungary
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 8/26/2011 Female 90 lb 7/19/2012 Physician Japan
Primary
Concomitant
Mycosis Fungoides Other Serious 5/1/2012 73 Male 198 lb 7/24/2012 Other Health Professional France
Primary
Secondary
Concomitant
Incorrect Route Of Drug Administration Hospitalization 6/1/2012 63 Male 243 lb 7/30/2012 Other Health Professional France
Primary
Secondary
Concomitant
Off Label Use Other Serious 65 Male 7/30/2012 Consumer Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 8/26/2011 Female 90 lb 8/1/2012 Physician Japan
Primary
Concomitant
Autoimmune Thrombocytopenia Hospitalization 6/13/2012 63 Male 243 lb 8/1/2012 Physician France
Primary
Secondary
Concomitant

Drug Data