Bisoprolol Fumarate combined with Pradaxa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Phlebitis Other Serious 10/13/2009 70 Female 11/30/2010 Physician
Primary
Concomitant
Abdominal Distension 12/3/2010 67 Male 1/13/2011 Consumer
Primary
Concomitant
Drug Clearance Decreased Death 1/27/2011 77 Male 252 lb 2/3/2011 Physician United States
Primary
Concomitant
Laceration 12/3/2010 67 Male 2/24/2011 Consumer United States
Primary
Concomitant
Haemorrhage 12/1/2010 78 Female 2/24/2011 Consumer United States
Primary
Concomitant
Dizziness 12/1/2010 82 Female 2/24/2011 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 1/7/2011 Male 203 lb 2/28/2011 Physician United States
Primary
Concomitant
Muscle Spasms 2/14/2011 80 Female 3/9/2011 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 3/15/2011 77 Male 194 lb 3/21/2011 Pharmacist United States
Primary
Concomitant
Chills 3/1/2011 Female 4/18/2011 Consumer United States
Primary
Concomitant
Hemisensory Neglect Hospitalization Male 165 lb 5/3/2011 Physician Ireland
Primary
Concomitant
Abdominal Pain Upper Life Threatening 3/30/2011 79 Male 128 lb 5/13/2011 Physician Japan
Primary
Concomitant
General Physical Condition Abnormal Hospitalization 3/22/2011 81 Male 5/13/2011 Physician Japan
Primary
Concomitant
Nausea Hospitalization 4/9/2011 85 Female 5/24/2011 Pharmacist Japan
Primary
Concomitant
Mucosal Ulceration Death Female 119 lb 5/25/2011 Pharmacist United Kingdom
Primary
Concomitant
Epistaxis Hospitalization 2/14/2011 80 Female 5/26/2011 Consumer United States
Primary
Concomitant
Regurgitation Other Serious 3/30/2011 79 Male 128 lb 5/26/2011 Physician Japan
Primary
Concomitant
Chest Pain 4/19/2011 83 Female 6/1/2011 Consumer United States
Primary
Concomitant
Bradycardia Life Threatening 5/19/2011 76 Female 6/1/2011 Physician Japan
Primary
Secondary
Dyspepsia Hospitalization 4/2/2011 78 Male 125 lb 6/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2011 73 Male 6/14/2011 Physician Japan
Primary
Concomitant
Dyspepsia Hospitalization 4/2/2011 78 Male 125 lb 6/22/2011 Physician Japan
Primary
Concomitant
Blood Pressure Decreased Hospitalization 5/19/2011 76 Female 106 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Distension 12/3/2010 67 Male 6/28/2011 Consumer United States
Primary
Secondary
Concomitant
Fall Hospitalization 3/8/2011 79 Male 7/5/2011 Other Health Professional France
Primary
Concomitant
Hypotension Hospitalization Male 7/5/2011 Pharmacist Canada
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/24/2011 55 Male 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization Male 165 lb 7/7/2011 Physician Ireland
Primary
Concomitant
Small Intestinal Haemorrhage Hospitalization 3/1/2011 78 Male 7/7/2011 Other Health Professional Canada
Primary
Concomitant
Interstitial Lung Disease Death 6/2/2011 73 Male 7/12/2011 Physician Japan
Primary
Concomitant
Malaise Hospitalization 3/8/2011 79 Male 123 lb 7/12/2011 Other Health Professional France
Primary
Concomitant
Haematuria Hospitalization 6/21/2011 74 Female 154 lb 7/15/2011 Physician Japan
Primary
Concomitant
Head Injury 12/3/2010 67 Male 7/22/2011 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2011 73 Male 132 lb 7/22/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 6/2/2011 80 Male 7/25/2011 Physician Japan
Primary
Concomitant
Bradycardia Hospitalization 5/19/2011 76 Female 106 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/19/2011 76 Male 180 lb 8/1/2011 Pharmacist Canada
Primary
Concomitant
Interstitial Lung Disease Death 6/2/2011 80 Male 8/2/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2011 73 Male 132 lb 8/5/2011 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 5/19/2011 71 Female 8/9/2011 Physician Malaysia
Primary
Concomitant
Pyrexia Hospitalization 3/28/2011 84 Male 8/10/2011 Consumer United States
Primary
Concomitant
Haematemesis Hospitalization 6/14/2011 60 8/17/2011 Physician Japan
Primary
Concomitant
Renal Failure Disability 6/13/2011 55 Male 147 lb 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Pain 7/1/2011 91 Female 8/18/2011 Consumer United States
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 11/23/2007 68 Male 8/18/2011 Other Health Professional Sweden
Primary
Concomitant
Drug Interaction Hospitalization 5/19/2011 76 Female 106 lb 8/18/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 6/2/2011 73 Male 132 lb 8/18/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2011 73 Male 132 lb 8/22/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/12/2011 78 Male 8/24/2011 Physician Japan
Primary
Concomitant
Activated Partial Thromboplastin Time Prolonged Other Serious 6/21/2011 94 Female 8/25/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2011 73 Male 132 lb 8/26/2011 Physician Japan
Primary
Concomitant
Blood Pressure Decreased Life Threatening 6/20/2011 77 Male 128 lb 8/26/2011 Pharmacist Japan
Primary
Concomitant
Anal Haemorrhage Other Serious 2/21/2010 59 Female 276 lb 8/29/2011 Physician Germany
Primary
Concomitant
Haematemesis Hospitalization 4/24/2011 77 Female 119 lb 8/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestine Carcinoma Hospitalization 5/31/2011 72 Male 8/31/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 6/2/2011 73 Male 132 lb 9/1/2011 Physician Japan
Primary
Concomitant
Large Intestine Carcinoma Hospitalization 5/31/2011 72 Male 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Anal Haemorrhage Other Serious 2/21/2010 59 Female 276 lb 9/2/2011 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Death 6/2/2011 79 Male 163 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Embolic Cerebral Infarction Other Serious 7/9/2011 79 Male 9/7/2011 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/1/2011 90 Female 107 lb 9/7/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 7/11/2011 75 Male 9/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Activated Partial Thromboplastin Time Prolonged 6/21/2011 94 Female 9/8/2011 Physician Japan
Primary
Concomitant
Oesophageal Ulcer Other Serious 6/14/2011 61 Female 98 lb 9/9/2011 Physician Japan
Primary
Concomitant
Hypotension Death 4/24/2011 77 Female 119 lb 9/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 6/21/2011 74 Female 154 lb 9/12/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/26/2011 90 Male 9/12/2011 Pharmacist Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/12/2011 78 Male 183 lb 9/13/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 7/11/2011 75 Male 9/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 80 Female 9/15/2011 Physician Brazil
Primary
Concomitant
Inflammation Of Wound Death 4/24/2011 77 Female 119 lb 9/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/20/2011 77 Male 128 lb 9/19/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 7/11/2011 75 Male 9/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 9/12/2011 85 Female 9/19/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/2/2011 79 Male 163 lb 9/19/2011 Physician Japan
Primary
Secondary
Concomitant
Haematemesis Hospitalization 4/24/2011 77 Female 119 lb 9/20/2011 Pharmacist United Kingdom
Primary
Concomitant
Gastrooesophageal Reflux Disease 6/23/2011 82 Male 238 lb 9/21/2011 Physician Australia
Primary
Concomitant
Anaemia Life Threatening 8/31/2011 79 Male 110 lb 9/22/2011 Physician Japan
Primary
Concomitant
Diarrhoea Life Threatening 9/12/2011 85 Female 9/22/2011 Physician Japan
Primary
Concomitant
Gastric Ulcer Other Serious 7/11/2011 75 Male 9/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 7/11/2011 75 Male 10/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haematemesis Other Serious 6/20/2011 77 Male 128 lb 10/4/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 9/12/2011 85 Female 10/4/2011 Physician Japan
Primary
Concomitant
Peripheral Artery Aneurysm Hospitalization 8/1/2011 80 Male 10/6/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/13/2011 55 Male 147 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 7/1/2011 90 Female 107 lb 10/6/2011 Physician Japan
Primary
Concomitant
Mouth Haemorrhage Other Serious 8/31/2011 79 Male 110 lb 10/7/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/26/2011 90 Male 183 lb 10/7/2011 Pharmacist Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/1/2011 79 Male 163 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/11/2011 66 Female 10/10/2011 Physician Norway
Primary
Concomitant
Haemorrhagic Infarction Hospitalization 3/1/2011 65 Female 181 lb 10/11/2011 Physician Luxembourg
Primary
Concomitant
Bleeding Time Prolonged Hospitalization 8/1/2011 80 Male 10/12/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 8/31/2011 79 Male 130 lb 10/13/2011 Physician Japan
Primary
Concomitant
Oesophageal Haemorrhage Hospitalization 6/14/2011 61 Female 98 lb 10/13/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/20/2011 77 Male 128 lb 10/14/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 10/20/2011 58 Male 172 lb 10/25/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Abdominal Pain Lower Hospitalization 8/1/2011 80 Male 11/1/2011 Physician Japan
Primary
Concomitant
Gaze Palsy Hospitalization 4/17/2009 74 Male 123 lb 11/2/2011 Physician Japan
Primary
Concomitant
Gastric Ph Decreased Other Serious 10/12/2011 64 Male 229 lb 11/3/2011 Physician Ireland
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/1/2011 68 Male 11/4/2011 Physician Norway
Primary
Concomitant
Loss Of Consciousness Hospitalization 10/3/2011 61 Male 214 lb 11/8/2011 Pharmacist Canada
Primary
Concomitant
Gaze Palsy Hospitalization 4/17/2009 74 Male 123 lb 11/10/2011 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 11/7/2011 93 Female 132 lb 11/14/2011 Physician Japan
Primary
Concomitant
Chest Pain Other Serious 10/12/2011 64 Male 229 lb 11/16/2011 Physician Ireland
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/1/2011 71 Female 154 lb 11/16/2011 Physician Portugal
Primary
Concomitant
Hyperbilirubinaemia Other Serious 10/20/2011 58 Male 172 lb 11/18/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/22/2011 75 Female 11/18/2011 Consumer United States
Primary
Concomitant
Haematemesis Death 10/12/2011 74 Male 176 lb 11/21/2011 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening Male 119 lb 11/21/2011 Physician Germany
Primary
Concomitant
Shock Haemorrhagic Death Male 119 lb 11/21/2011 Physician Germany
Primary
Concomitant
Shock Haemorrhagic Life Threatening Male 119 lb 11/21/2011 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening Male 119 lb 11/21/2011 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 10/20/2011 58 Male 172 lb 11/22/2011 Physician Japan
Primary
Secondary
Concomitant
Arthralgia 6/1/2011 62 Female 11/22/2011 Consumer United States
Primary
Concomitant
Melaena Death 10/11/2011 74 Male 176 lb 11/28/2011 Physician Germany
Primary
Concomitant
Gastritis Hospitalization 67 Female 11/28/2011 Physician Germany
Primary
Concomitant
Death Death 10/11/2011 74 Male 176 lb 11/28/2011 Physician Germany
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 11/7/2011 91 Female 132 lb 11/29/2011 Physician Japan
Primary
Concomitant
Haemobilia Other Serious Male 183 lb 12/1/2011 Physician Germany
Primary
Concomitant
Oedema Peripheral Disability 9/27/2011 52 Male 209 lb 12/2/2011 Physician Germany
Primary
Concomitant
Shock Life Threatening 11/24/2011 70 Female 113 lb 12/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/12/2011 69 Male 12/7/2011 Physician Japan
Primary
Secondary
Uterine Haemorrhage Death 10/17/2011 61 Female 425 lb 12/8/2011 Physician Germany
Primary
Concomitant
Shock Death 11/24/2011 70 Female 113 lb 12/8/2011 Physician Japan
Primary
Secondary
Concomitant
Coagulopathy Hospitalization 11/29/2011 87 Female 113 lb 12/8/2011 Physician Japan
Primary
Concomitant
Aphasia Life Threatening 11/3/2011 73 Male 12/9/2011 Other Health Professional Australia
Primary
Concomitant
Embolic Stroke Hospitalization 12/9/2011 77 Female 12/12/2011 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 9/8/2011 Male 12/13/2011 Physician Germany
Primary
Concomitant
Cerebral Infarction Hospitalization Female 12/13/2011 Physician Germany
Primary
Concomitant
Haemorrhage Subcutaneous Hospitalization 11/10/2011 50 Male 137 lb 12/14/2011 Physician Japan
Primary
Concomitant
Coagulopathy 11/29/2011 87 Female 113 lb 12/15/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 12/1/2011 64 Male 155 lb 12/15/2011 Physician Japan
Primary
Concomitant
Aplastic Anaemia Hospitalization 9/1/2011 76 Female 12/16/2011 Physician France
Primary
Secondary
Concomitant
Embolic Stroke Life Threatening 12/9/2011 77 Female 12/16/2011 Physician Japan
Primary
Concomitant
Thrombosis In Device Life Threatening 12/18/2011 79 12/23/2011 Physician Belgium
Primary
Concomitant
Renal Failure Life Threatening 12/18/2011 79 12/23/2011 Physician Belgium
Primary
Concomitant
Thrombosis In Device Life Threatening 12/18/2011 79 12/23/2011 Physician Belgium
Primary
Concomitant
Thrombosis In Device Life Threatening 12/18/2011 79 12/23/2011 Physician Belgium
Primary
Concomitant
Myocardial Infarction Hospitalization 12/18/2011 79 12/23/2011 Physician Belgium
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/24/2011 70 Female 113 lb 12/23/2011 Physician Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 6/25/2011 84 Male 12/27/2011 Other Health Professional France
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 12/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Fall Hospitalization 11/24/2011 70 Female 113 lb 12/27/2011 Physician Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 11/10/2011 50 Male 137 lb 12/27/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 10/1/2011 64 Male 134 lb 12/28/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 10/19/2011 58 Male 172 lb 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/18/2011 79 Female 154 lb 1/3/2012 Physician Netherlands
Primary
Concomitant
Aplastic Anaemia Hospitalization 9/1/2011 76 Female 1/5/2012 Physician France
Primary
Secondary
Concomitant
Coagulation Time Prolonged Hospitalization 11/28/2011 78 Male 145 lb 1/6/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Oedema Genital Hospitalization 10/18/2011 Male 1/10/2012 Physician Singapore
Primary
Concomitant

Drug Data