Bisoprolol Fumarate combined with Nicorandil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ischaemic Stroke Other Serious 7/7/2004 Female 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 3/13/2006 82 Female 8/8/2006 Denmark
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/10/2006 60 Male 284 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/10/2006 60 Male 271 lb 9/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 7/1/2006 82 Male 10/23/2006 Pharmacist United Kingdom
Primary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hormone Level Abnormal Hospitalization 3/22/2005 Female 137 lb 12/14/2006 Consumer United Kingdom
Primary
Concomitant
Ventricular Dysfunction Other Serious 6/5/2004 Female 112 lb 12/29/2006 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Ventricular Fibrillation Life Threatening 3/4/2004 62 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 7/1/2006 82 Male 1/16/2007 Pharmacist United Kingdom
Primary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Dysfunction Life Threatening 6/5/2004 69 Female 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/1/2007 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 9/1/2006 46 Male 344 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 4/28/2007 62 Female 174 lb 5/11/2007 Consumer United Kingdom
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 3/1/2006 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 2/7/2006 69 Male 176 lb 5/25/2007 Ireland
Primary
Concomitant
Weight Decreased Other Serious 3/8/2007 70 Female 5/29/2007 Physician United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 4/28/2007 62 Female 174 lb 6/4/2007 Consumer United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 4/28/2007 62 Female 174 lb 6/22/2007 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 2/7/2006 69 Male 176 lb 6/22/2007 Ireland
Primary
Concomitant
Weight Decreased Hospitalization 5/3/2007 75 Male 187 lb 7/16/2007 Other Health Professional France
Primary
Concomitant
Weight Decreased Hospitalization 5/3/2007 75 Male 187 lb 7/27/2007 Other Health Professional France
Primary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 10/20/2007 55 Male 181 lb 11/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 7/30/2007 59 Male 12/18/2007 United Kingdom
Primary
Secondary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 1/21/2008 Consumer United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2007 Female 132 lb 1/22/2008 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/30/2007 Male 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Epistaxis Life Threatening 1/1/2007 76 Male 186 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 2/11/2008 United States
Primary
Concomitant
Angina Pectoris Hospitalization 2/16/2008 59 Female 156 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 3/4/2008 Consumer United Kingdom
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 3/7/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Dysfunction Other Serious 11/5/2004 3/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 11/5/2004 69 Female 112 lb 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Dysfunction Other Serious 11/5/2004 69 Female 112 lb 3/27/2008 United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 11/5/2004 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 11/5/2004 69 Female 112 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Dysfunction Other Serious 6/5/2004 69 Female 112 lb 4/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Dysfunction Other Serious 6/5/2004 4/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 11/5/2004 Female 112 lb 4/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Abscess Intestinal Hospitalization 3/7/2008 Female 156 lb 4/29/2008 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization Female 4/30/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Other Serious 82 Female 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 3/31/2008 64 Male 5/13/2008 Physician
Primary
Concomitant
Panophthalmitis Disability 11/9/2007 Male 176 lb 7/4/2008 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 8/4/2008 Consumer United Kingdom
Primary
Concomitant
Panophthalmitis Disability 11/10/2007 Male 176 lb 8/13/2008 Physician United Kingdom
Primary
Concomitant
Incorrect Dose Administered Hospitalization 6/1/2008 Female 174 lb 8/22/2008 Physician United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/6/2008 77 Male 180 lb 8/25/2008 United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 9/5/2008 Consumer United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 84 Female 9/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 12/1/2007 Male 9/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Alveolitis Fibrosing Other Serious 1/1/2007 60 Male 9/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 9/29/2008 Male 267 lb 10/16/2008 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 3/13/2006 82 Female 10/22/2008 United Kingdom
Primary
Secondary
Concomitant
Hypoaesthesia Disability 7/14/2008 80 Female 10/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypoaesthesia Other Serious 7/14/2008 80 Female 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Acidosis Other Serious 8/25/2008 Male 154 lb 11/12/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 8/25/2008 Male 11/20/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 69 Male 11/21/2008 Italy
Primary
Concomitant
Pyrexia Hospitalization 8/25/2008 Male 154 lb 11/26/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 11/29/2008 Male 12/18/2008 Physician United Kingdom
Primary
Concomitant
Vertigo Hospitalization 77 Female 3/20/2009 Austria
Primary
Secondary
Concomitant
Atrioventricular Block Complete Hospitalization 9/23/2008 76 Male 3/20/2009 France
Primary
Secondary
Concomitant
Iga Nephropathy Hospitalization 9/23/2008 76 Male 3/26/2009 France
Primary
Secondary
Concomitant
Vertigo Hospitalization 77 Female 174 lb 3/26/2009 Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 77 Female 174 lb 3/26/2009 Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 1/6/2009 79 Female 5/1/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Thrombocytopenia Life Threatening 3/16/2009 69 Male 165 lb 5/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 1/6/2009 79 Female 5/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 3/16/2009 69 Male 165 lb 5/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 3/16/2009 69 Male 5/14/2009 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Hospitalization 5/1/2009 80 Female 7/14/2009 Physician France
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/1/2009 80 Female 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 8/17/2009 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 8/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/10/2009 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/26/2009 71 Female 11/17/2009 Physician Japan
Primary
Concomitant
Trismus Hospitalization 9/20/2009 67 Female 12/24/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 45 Male 1/26/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 4/12/2010 68 Female 5/4/2010 Other Health Professional France
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 3/11/2010 5/12/2010 Consumer United Kingdom
Primary
Concomitant
Pneumonitis Life Threatening 5/1/2010 Female 125 lb 8/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 1/1/2010 10/8/2010 Pharmacist Italy
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 63 Male 190 lb 11/23/2010 Physician United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 1/1/2010 Female 2/9/2011 Pharmacist Ireland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/26/2011 74 Male 187 lb 2/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Other Serious 1/26/2011 74 Male 187 lb 2/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Life Threatening 1/26/2011 74 Male 187 lb 2/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 7/10/2009 78 Female 101 lb 2/15/2011 Physician Japan
Primary
Concomitant
Hepatorenal Failure Other Serious 1/26/2011 74 Male 2/15/2011 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 1/26/2011 74 Male 187 lb 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Life Threatening 1/26/2011 74 Male 187 lb 2/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nodal Arrhythmia Hospitalization 1/26/2011 74 Male 2/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Jaundice Life Threatening 1/26/2011 74 Male 187 lb 2/22/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiovascular Insufficiency Other Serious 1/26/2011 74 Male 2/22/2011 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/26/2011 74 Male 187 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/26/2011 74 Male 187 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 71 Male 3/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Death 88 Female 2/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Life Threatening 1/26/2011 74 Male 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fibrinolysis Life Threatening 71 Male 3/4/2011 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 1/26/2011 74 Male 85 lb 2/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Globulins Increased Death 7/21/2008 85 117 lb 4/4/2011 Consumer United Kingdom
Primary
Concomitant
Radial Nerve Palsy Death 7/21/2008 85 117 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Cough Hospitalization 7/1/2010 75 Female 176 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 12/20/2010 81 Male 4/26/2011 United Kingdom
Primary
Secondary
Concomitant
Pleura Carcinoma Hospitalization 12/20/2010 81 Male 5/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cough Hospitalization 7/28/2009 75 Female 176 lb 5/20/2011 Consumer United Kingdom
Primary
Concomitant
Liver Disorder Death 7/10/2009 78 Female 101 lb 6/27/2011 Physician Japan
Primary
Concomitant
Rash Other Serious 4/10/2011 69 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Other Serious 3/18/2009 61 Male 220 lb 8/17/2011 Physician United Kingdom
Primary
Concomitant
Dyspnoea Disability 8/22/2011 66 Male 276 lb 9/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Disability 68 Male 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/2/2011 79 Male 9/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 7/17/2011 76 Male 139 lb 10/27/2011 Physician Japan
Primary
Concomitant
Injection Site Extravasation Hospitalization 8/12/2011 71 Male 115 lb 11/11/2011 Physician Japan
Primary
Concomitant
Bacteraemia Other Serious 7/16/2011 76 Male 139 lb 12/1/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 8/8/2011 71 Male 115 lb 12/28/2011 Physician Japan
Primary
Concomitant
Blood Fibrinogen Increased Hospitalization 1/23/2012 85 Male 2/17/2012 Consumer United Kingdom
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/8/2012 61 Male 278 lb 3/1/2012 Physician Japan
Primary
Secondary
Concomitant
Pruritus Other Serious 2/2/2012 71 Female 3/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 2/2/2012 71 Female 3/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/2/2012 71 Female 3/26/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 2/2/2012 71 Female 3/26/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Product Contamination Microbial Other Serious 2/2/2012 71 Female 3/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 2/2/2012 71 Female 4/4/2012 Other Health Professional
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/2/2012 71 Female 4/12/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 2/2/2012 71 Female 4/12/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Product Contamination Microbial Other Serious 2/2/2012 71 Female 4/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 3/27/2012 75 Female 4/19/2012 Physician United Kingdom
Primary
Concomitant
Rash Maculo-papular Other Serious 2/2/2012 71 Female 4/20/2012 Pharmacist
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 2/2/2012 71 Female 4/26/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Carotid Artery Stenosis Other Serious 10/26/2011 65 Male 5/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Product Contamination Microbial Other Serious 2/2/2012 71 Female 5/7/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hemiparesis Death 3/1/2012 64 Male 200 lb 5/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Dizziness Hospitalization 3/25/2010 47 Male 203 lb 6/25/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data