Bisoprolol Fumarate combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 3/14/2006 Other Health Professional Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/17/2006 Physician Austria
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 12/26/2004 66 Male 163 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Rash Other Serious 12/22/2004 57 Male 210 lb 5/26/2006 Consumer Canada
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 1/30/2006 78 Female 6/19/2006 Canada
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 4/10/2006 56 Female 182 lb 6/26/2006 United Kingdom
Primary
Secondary
Concomitant
Adenocarcinoma Other Serious 4/24/2006 74 Male 7/6/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 4/24/2006 74 Male 7/12/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Head Injury Hospitalization 95 Male 7/11/2006 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Death 4/16/2006 70 Male 7/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence 6/1/2005 55 Male 7/21/2006 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/21/2006 United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 3/1/2000 Male 8/3/2006 Physician United Kingdom
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 3/27/2006 72 Male 198 lb 8/14/2006 Physician Germany
Primary
Concomitant
Transurethral Prostatectomy Other Serious 4/24/2006 74 Male 8/17/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/9/2006 69 Female 8/18/2006 Other Health Professional Denmark
Primary
Concomitant
Renal Failure Life Threatening 1/23/2006 71 Male 187 lb 8/24/2006 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 8/24/2006 55 Female 11/14/2006 Consumer United Kingdom
Primary
Concomitant
Ischaemic Cerebral Infarction Other Serious 5/16/2006 66 Female 9/28/2007 Physician Germany
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2007 48 Male 328 lb 10/16/2007 Physician United Kingdom
Primary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/5/2007 Physician United Kingdom
Primary
Concomitant
Death Death 11/29/2007 52 Male 212 lb 1/3/2008 Physician Switzerland
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/28/2008 69 Female 3/13/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 70 Female 6/20/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 67 Male 209 lb 6/17/2008 Physician Switzerland
Primary
Concomitant
Platelet Count Decreased Other Serious 73 Male 7/1/2008 Consumer France
Primary
Concomitant
Interacting
Vascular Graft Other Serious 1/1/2008 60 Female 187 lb 7/1/2008 Physician Germany
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/30/2008 Female 320 lb 7/11/2008 Consumer United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 7/28/2008 Physician United Kingdom
Primary
Concomitant
Renal Cancer Life Threatening 2/1/2008 Female 203 lb 8/25/2008 Physician Germany
Primary
Concomitant
Syncope Hospitalization 6/6/2008 77 Male 180 lb 8/25/2008 United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 68 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 70 Female 9/11/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 9/29/2008 Male 267 lb 10/16/2008 Consumer United Kingdom
Primary
Concomitant
Pleurisy Life Threatening 1/1/2008 62 Male 397 lb 3/18/2009 Physician Germany
Primary
Concomitant
Renal Failure Acute Life Threatening 3/2/2009 4/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 4/1/2009 61 Male 5/11/2009 Physician France
Primary
Concomitant
Speech Disorder Life Threatening 11/4/2008 67 Female 5/11/2009 Other Health Professional
Primary
Secondary
Concomitant
Post Procedural Haematoma Hospitalization 47 176 lb 6/10/2009 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 5/1/2009 54 6/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hypertension Hospitalization 5/1/2009 55 Female 7/28/2009 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/25/2009 74 Male 271 lb 7/27/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vitritis Other Serious 7/19/2009 Female 8/20/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Somatoform Disorder Hospitalization 1/23/2009 Male 1/22/2010 Physician Germany
Primary
Concomitant
Benign Prostatic Hyperplasia Hospitalization 11/1/2008 Male 198 lb 1/22/2010 Germany
Primary
Concomitant
Hypokalaemia Life Threatening 11/24/2009 66 Female 209 lb 1/25/2010 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/3/2009 Male 86 lb 1/25/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/27/2009 Male 227 lb 1/25/2010 Physician Belgium
Primary
Concomitant
Arrhythmia Hospitalization 4/1/2009 Male 194 lb 3/12/2010 Other Health Professional Canada
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Life Threatening 80 Male 4/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Petechiae Life Threatening 80 Male 4/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 5/26/2008 66 Male 234 lb 4/27/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Benign Prostatic Hyperplasia Other Serious 4/23/2010 59 Male 165 lb 5/5/2010 Consumer Canada
Primary
Concomitant
Vitamin B12 Decreased Other Serious Male 9/1/2010 Consumer Netherlands
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 7/19/2010 89 Female 9/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Life Threatening 3/17/2010 69 Male 267 lb 9/2/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Sudden Death Death 5/7/2009 61 Male 168 lb 9/3/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/1/2010 75 Female 9/3/2010 Other Health Professional France
Primary
Secondary
Sudden Death Death 5/7/2009 61 Male 168 lb 9/3/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/20/2010 63 Male 9/9/2010 Other Health Professional France
Primary
Secondary
Concomitant
Cytolytic Hepatitis Death 6/30/2009 80 Male 9/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 11/28/2007 65 Female 9/20/2010 Other Health Professional France
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 1/14/2009 76 Male 9/17/2010 Belgium
Primary
Secondary
Concomitant
Empyema Hospitalization 8/4/2010 51 Male 183 lb 9/27/2010 Physician Poland
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 7/20/2010 60 Female 9/27/2010 Pharmacist United Kingdom
Primary
Concomitant
Drug Administration Error Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 203 lb 10/6/2010 Other Health Professional
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/1/2010 73 Female 10/12/2010 Physician Italy
Primary
Concomitant
Respiratory Failure Other Serious 7/20/2010 63 Male 10/27/2010 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2010 73 Female 10/18/2010 Physician Italy
Primary
Concomitant
Sepsis Hospitalization 11/10/2010 74 Male 11/18/2010 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Cholestatic Other Serious 10/12/2010 74 Male 11/30/2010 Physician Italy
Primary
Concomitant
Wheezing Other Serious 68 Male 261 lb 12/3/2010 Physician Canada
Primary
Concomitant
Cytolytic Hepatitis Death 6/30/2009 80 9/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Tuberculin Test Positive 12/22/2010 Other Health Professional United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 8/26/2010 69 Male 1/4/2011 Physician Canada
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 9/1/2010 62 Female 1/19/2011 Other Health Professional France
Primary
Concomitant
Muscle Spasms Hospitalization 4/1/2010 63 Female 2/2/2011 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 1/11/2011 76 Male 2/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Chest Discomfort Life Threatening 1/11/2011 76 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin T Increased Hospitalization 1/11/2011 76 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/4/2011 73 Male 3/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/10/2010 71 Male 220 lb 3/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/11/2011 76 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2010 66 Male 3/9/2011 Other Health Professional Switzerland
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 1/11/2011 76 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/1/2010 69 3/11/2011 Other Health Professional Canada
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/12/2010 67 Male 3/28/2011 Consumer United Kingdom
Primary
Concomitant
Diarrhoea Life Threatening 1/11/2011 76 Male 3/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abdominal Wall Haematoma Hospitalization 1/24/2011 84 Female 3/29/2011 Other Health Professional France
Primary
Concomitant
Interacting
Diarrhoea Life Threatening 1/11/2011 76 Male 3/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/11/2011 76 Male 3/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Injection Site Pain Hospitalization 4/1/2010 63 Female 4/4/2011 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 1/11/2011 76 Male 3/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 1/24/2011 84 Female 4/11/2011 Other Health Professional France
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 3/25/2011 56 Female 126 lb 4/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/24/2011 84 Female 4/13/2011 Other Health Professional France
Primary
Concomitant
Interacting
Diarrhoea Hospitalization 1/11/2011 76 Male 4/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 4/1/2011 52 Female 4/20/2011 Consumer Turkey
Primary
Concomitant
Lactic Acidosis Life Threatening 3/25/2011 56 Female 126 lb 4/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lactic Acidosis Life Threatening 3/25/2011 56 Female 126 lb 4/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Life Threatening 3/25/2011 56 Female 126 lb 4/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 11/12/2010 72 Male 4/21/2011 Other Health Professional France
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 1/11/2011 76 Male 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 10/10/2010 71 Male 220 lb 4/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Death 8/26/2010 69 Male 4/15/2011 Physician Canada
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 3/7/2011 52 Female 5/5/2011 Other Health Professional France
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 1/18/2011 74 Male 141 lb 5/4/2011 Consumer United States
Primary
Concomitant
Gastric Ulcer Hospitalization 1/18/2011 74 Male 141 lb 5/4/2011 Physician United States
Primary
Concomitant
Escherichia Bacteraemia Hospitalization 2/5/2010 71 Male 5/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 6/14/2010 56 Male 5/19/2011 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Death 12/18/2010 79 Male 264 lb 5/25/2011 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/24/2011 84 Female 6/2/2011 Other Health Professional France
Primary
Concomitant
Interacting
Alcohol Use Other Serious 12/9/2009 61 Male 7/20/2011 Physician Finland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/19/2011 61 Female 8/1/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 4/1/2011 52 Female 8/2/2011 Consumer Turkey
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/19/2011 61 Female 8/9/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 8/4/2011 58 Male 8/26/2011 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 53 Male 303 lb 8/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 2/1/2011 59 Female 9/9/2011 Physician United States
Primary
Concomitant
Impaired Healing Hospitalization 8/4/2011 58 Male 9/9/2011 Physician Germany
Primary
Secondary
Concomitant
Anaemia Other Serious 1/1/2011 84 Female 9/15/2011 Other Health Professional France
Primary
Concomitant
Interacting
Oedema Peripheral Hospitalization 1/1/2011 84 Female 9/19/2011 Other Health Professional France
Primary
Concomitant
Interacting
Gait Disturbance Hospitalization 8/30/2011 86 Male 172 lb 9/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 5/12/2011 81 Male 9/22/2011 Other Health Professional France
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 5/12/2011 81 Male 9/27/2011 Other Health Professional France
Primary
Concomitant
Wound Infection Hospitalization 8/4/2011 58 Male 280 lb 11/23/2011 Physician Germany
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 9/29/2011 76 Female 11/23/2011 Consumer Germany
Primary
Concomitant
Haemoglobin Decreased Hospitalization 10/25/2011 70 Female 148 lb 11/24/2011 Other Health Professional Canada
Primary
Concomitant
Antipsychotic Drug Level Below Therapeutic Other Serious Male 12/27/2011 Physician United Kingdom
Primary
Concomitant
Pruritus Hospitalization 11/17/2011 62 Male 1/3/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Acute Life Threatening 10/10/2010 64 Female 1/9/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pruritus Hospitalization 11/17/2011 62 Male 1/17/2012 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/9/2009 82 Female 150 lb 2/2/2012 Consumer Germany
Primary
Secondary
Concomitant
Constipation Hospitalization 7/9/2009 82 Female 150 lb 2/2/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Rash Maculo-papular Hospitalization 11/17/2011 62 Male 2/23/2012 Other Health Professional France
Primary
Secondary
Concomitant
Dyspnoea Other Serious Male 209 lb 3/14/2012 Physician Germany
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious Female 3/14/2012 United Kingdom
Primary
Concomitant
Nausea Hospitalization 5/25/2011 62 Female 3/14/2012 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/2/2012 70 Female 108 lb 3/23/2012 Physician Switzerland
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/11/2012 84 Female 3/29/2012 Physician Slovenia
Primary
Secondary
Concomitant
Epistaxis Hospitalization 2/18/2012 77 Male 3/30/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization 2/17/2012 67 Male 4/2/2012 Physician Netherlands
Primary
Concomitant
Proteinuria Hospitalization 1/2/2012 70 Female 108 lb 4/2/2012 Physician Switzerland
Primary
Secondary
Concomitant
Epistaxis Hospitalization 2/18/2012 77 Male 4/3/2012 Other Health Professional Canada
Primary
Secondary
Concomitant

Drug Data