Bisoprolol Fumarate combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Other Serious 3/1/2005 73 Male 172 lb 5/25/2006 Physician Belgium
Primary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Eosinophilia Hospitalization 11/7/2005 67 Female 109 lb 6/16/2006 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 5/4/2006 67 Male 243 lb 7/24/2006 Physician Austria
Primary
Concomitant
Diarrhoea 1/1/2005 77 Female 220 lb 8/1/2006 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 66 Male 7/28/2006 Pharmacist Germany
Primary
Concomitant
Hypercalcaemia Other Serious 10/24/2006 Male 11/21/2006 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 4/26/2006 36 Female 117 lb 1/11/2007 Physician Ireland
Primary
Concomitant
Hyperglycaemia Other Serious 11/28/2006 61 Female 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 75 Female 7/18/2007 Belgium
Primary
Secondary
Concomitant
Ischaemic Cerebral Infarction Other Serious 5/16/2006 66 Female 9/28/2007 Physician Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 10/24/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pallor Life Threatening 9/19/2007 69 Male 11/6/2007 United Kingdom
Primary
Concomitant
Hypertonia Hospitalization 8/10/2007 55 Male 220 lb 1/2/2008 Physician Switzerland
Primary
Concomitant
Thrombosis Death 7/22/2007 62 Male 1/21/2008 Consumer Italy
Primary
Concomitant
Ischaemic Cerebral Infarction Other Serious 5/16/2006 66 Female 2/8/2008 Physician Germany
Primary
Concomitant
Bronchospasm Other Serious 2/23/2008 62 Male 3/7/2008 Physician Spain
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 11/13/2007 60 Male 231 lb 7/30/2008 Physician Switzerland
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 11/13/2007 60 Male 231 lb 8/27/2008 Physician Switzerland
Primary
Concomitant
Myeloid Maturation Arrest Life Threatening 4/7/2008 8/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Bronchospasm Other Serious 2/23/2008 62 Male 10/14/2008 Physician Spain
Primary
Secondary
Concomitant
Pemphigus Disability 64 Female 10/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/1/2008 Male 10/18/2008 Physician Italy
Primary
Concomitant
Pemphigus Disability 3/1/2008 64 Female 10/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 4/16/2006 Male 10/22/2008 Denmark
Primary
Concomitant
Pemphigus Disability 3/1/2008 64 Female 121 lb 10/29/2008 Physician United Kingdom
Primary
Concomitant
Pemphigus Disability 3/1/2008 64 Female 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Hospitalization 1/1/2008 64 Male 12/30/2008 Physician France
Primary
Concomitant
Vomiting Hospitalization 8/26/2008 61 Female 4/13/2009 Physician Spain
Primary
Secondary
Concomitant
Renal Cancer Death 5/1/2007 78 Male 143 lb 5/8/2009 Other Health Professional Austria
Primary
Concomitant
Delirium Hospitalization 11/3/2008 75 Female 6/3/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 5/1/2009 Female 430 lb 6/11/2009 Consumer United States
Primary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 9/16/2009 Other Health Professional France
Primary
Secondary
Renal Impairment Life Threatening 6/25/2009 76 Male 187 lb 9/25/2009 Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 6/25/2009 76 Male 187 lb 9/30/2009 Germany
Primary
Concomitant
Interacting
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 10/28/2009 Other Health Professional France
Primary
Secondary
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 11/4/2009 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 11/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 11/13/2009 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 12/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Death 6/19/2008 78 Male 12/31/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hypoglycaemic Seizure Other Serious 10/2/2008 59 Male 1/12/2010 Consumer Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 2/18/2010 Other Health Professional France
Primary
Secondary
Renal Failure Hospitalization 73 Female 2/19/2010 Consumer United Kingdom
Primary
Concomitant
Renal Failure Death 6/19/2008 78 Male 3/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 3/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Petechiae Life Threatening 80 Male 3/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 4/1/2010 Other Health Professional France
Primary
Secondary
Overdose Life Threatening 1/12/2010 78 Male 4/2/2010 Other Health Professional Spain
Primary
Secondary
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious Male 4/5/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/27/2010 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Hospitalization 5/26/2008 66 Male 5/14/2010 Consumer Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 4/1/2010 74 Male 220 lb 5/12/2010 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 5/21/2010 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2009 75 Female 143 lb 9/14/2010 Other Health Professional France
Primary
Secondary
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/20/2010 Physician United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 9/16/2010 United Kingdom
Primary
Concomitant
Lipase Increased Other Serious 9/11/2010 46 Male 10/21/2010 Other Health Professional Italy
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 63 Male 190 lb 11/23/2010 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 12/3/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Angioedema Other Serious 12/1/2010 68 Male 12/23/2010 Other Health Professional Canada
Primary
Concomitant
Muscle Spasms Other Serious 4/12/2011 60 Female 4/29/2011 Pharmacist Ireland
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 10/7/2010 Male 220 lb 5/3/2011 Physician United Kingdom
Primary
Concomitant
Myalgia Hospitalization 2/6/2011 63 Female 236 lb 5/12/2011 Other Health Professional France
Primary
Concomitant
Myalgia Hospitalization 2/6/2011 63 Female 236 lb 5/18/2011 Other Health Professional France
Primary
Concomitant
Muscle Spasms Other Serious 4/12/2011 60 Female 5/19/2011 Pharmacist Ireland
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 6/20/2005 51 Female 269 lb 5/20/2011 Physician Germany
Primary
Concomitant
Muscle Spasms Other Serious 4/12/2011 60 Female 5/27/2011 Pharmacist Ireland
Primary
Secondary
Concomitant
Anaemia Hospitalization 1/17/2011 84 Female 6/9/2011 Other Health Professional France
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious 4/21/2011 69 Male 161 lb 6/17/2011 Physician Greece
Primary
Concomitant
Atrophy Other Serious 7/18/2010 64 Female 7/5/2011 Physician Canada
Primary
Concomitant
Blood Bilirubin Increased Other Serious 73 Female 7/12/2011 Other Health Professional Spain
Primary
Concomitant
Pulmonary Embolism Other Serious 4/21/2011 69 Male 161 lb 7/25/2011 Physician Greece
Primary
Concomitant
Renal Failure Acute Hospitalization 7/22/2011 35 Male 8/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 8/4/2011 58 Male 295 lb 8/22/2011 Physician Germany
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 8/30/2011 86 Male 172 lb 9/15/2011 Physician Switzerland
Primary
Concomitant
Pulmonary Embolism Life Threatening 4/21/2011 69 Male 161 lb 9/23/2011 Physician Greece
Primary
Concomitant
Pulmonary Embolism Other Serious 4/21/2011 69 Male 161 lb 9/29/2011 Physician Greece
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/1/2010 85 Female 165 lb 9/28/2011 Physician United States
Primary
Concomitant
Interacting
Wound Infection Hospitalization 8/4/2011 58 Male 280 lb 10/12/2011 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 4/21/2011 69 Male 161 lb 10/31/2011 Physician Greece
Primary
Concomitant
Angioedema Other Serious 6/28/2011 57 Female 262 lb 11/23/2011 Physician France
Primary
Concomitant
Pancreatitis Hospitalization 8/16/2011 12/5/2011 Physician Finland
Primary
Concomitant
Pancreatitis Hospitalization 8/16/2011 12/13/2011 Physician Finland
Primary
Concomitant
Pneumonia Death 73 Male 236 lb 12/21/2011 Germany
Primary
Concomitant
Hypoglycaemia Hospitalization 12/14/2011 54 Male 1/4/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 52 Female 149 lb 1/11/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/21/2011 69 Male 161 lb 1/17/2012 Physician Greece
Primary
Concomitant
Angioplasty Hospitalization 1/1/2010 69 Female 1/20/2012 Consumer Brazil
Primary
Secondary
Concomitant
Fatigue Life Threatening 4/21/2011 69 Male 161 lb 1/27/2012 Physician Greece
Primary
Concomitant
Headache Other Serious 11/3/2011 74 Female 2/22/2012 Other Health Professional Poland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 11/3/2011 74 Female 2/24/2012 Other Health Professional Poland
Primary
Secondary
Concomitant
Headache Other Serious 3/20/2011 73 Female 176 lb 2/24/2012 Physician Poland
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/21/2011 69 Male 161 lb 2/27/2012 Physician Greece
Primary
Concomitant
Headache Other Serious 1/1/2010 66 Male 3/8/2012 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 2/21/2012 45 Male 227 lb 3/19/2012 Other Health Professional United Kingdom
Primary
Concomitant
Cholangitis Hospitalization 12/9/2011 64 Male 172 lb 3/30/2012 Physician Germany
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 52 Female 149 lb 4/17/2012 Physician France
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 52 Female 149 lb 4/17/2012 Physician France
Primary
Secondary
Concomitant
Laryngeal Oedema Other Serious 5/16/2012 73 Female 132 lb 6/5/2012 Consumer Brazil
Primary
Concomitant
Petit Mal Epilepsy Other Serious Male 6/6/2012 Physician France
Primary
Concomitant
Cholecystitis Acute Hospitalization 5/27/2012 80 Male 6/6/2012 Physician Finland
Primary
Secondary
Concomitant
Flank Pain Hospitalization 5/27/2012 80 Male 6/14/2012 Physician Finland
Primary
Secondary
Concomitant
Flank Pain Hospitalization 5/27/2012 80 Male 6/20/2012 Physician Finland
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 5/15/2012 47 Male 220 lb 6/26/2012 Physician France
Primary
Secondary
Concomitant
Abnormal Behaviour Other Serious 5/15/2012 47 Male 220 lb 7/4/2012 Other Health Professional France
Primary
Secondary
Concomitant
Headache 38 Female 7/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Bronchitis Other Serious 1/12/2012 59 Female 192 lb 7/13/2012 Physician Germany
Primary
Concomitant
Hepatic Failure Hospitalization 3/6/2012 58 Female 179 lb 7/13/2012 Physician Hungary
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 8/1/2011 66 Male 197 lb 7/16/2012 Other Health Professional Australia
Primary
Concomitant
C-reactive Protein Increased Other Serious 5/1/2012 Female 7/16/2012 Physician Germany
Primary
Concomitant
Cholecystitis Acute Hospitalization 5/27/2012 80 Male 7/16/2012 Physician Finland
Primary
Secondary
Concomitant
Bradycardia Hospitalization 6/11/2012 70 Male 7/3/2012 Other Health Professional Denmark
Primary
Concomitant
Adenocarcinoma Other Serious 4/24/2006 73 Male 7/23/2012 Physician Ireland
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 6/11/2012 68 Female 7/24/2012 Physician Sweden
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization Male 249 lb 7/27/2012 Other Health Professional Germany
Primary
Concomitant
Angioedema Other Serious 7/27/2012 Consumer Germany
Primary
Secondary
Atrioventricular Block Complete Hospitalization 6/10/2012 62 Female 7/30/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Psychomotor Retardation Hospitalization 7/19/2012 65 Female 7/31/2012 Physician Italy
Primary
Secondary
Concomitant
Aortic Stenosis Other Serious 62 Male 7/31/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Angioedema Other Serious 7/31/2012 Consumer United States
Primary
Secondary
Angioedema Other Serious 7/31/2012 Other Health Professional United States
Primary
Secondary
Suicide Attempt Hospitalization 12/25/2011 8/1/2012 Consumer United States
Primary
Secondary
Concomitant
Impaired Healing Other Serious 5/16/2012 63 Male 258 lb 8/1/2012 Physician Germany
Primary
Concomitant
Abdominal Pain Lower Hospitalization 5/26/2012 62 Female 8/1/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Bradyphrenia Hospitalization 7/19/2012 65 Female 8/1/2012 Physician Italy
Primary
Secondary
Concomitant
Bradykinesia Hospitalization 7/19/2012 65 Female 8/2/2012 Physician Italy
Primary
Secondary
Concomitant
Bradyphrenia Other Serious 7/19/2012 65 Female 8/2/2012 Physician Italy
Primary
Secondary
Concomitant
Angioedema Other Serious 8/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/11/2011 61 Male 229 lb 8/3/2012 Physician Italy
Primary
Concomitant
Abdominal Pain Lower Hospitalization 5/26/2012 62 Female 8/2/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 235 lb 8/1/2012 Consumer United States
Primary
Concomitant
Flushing Female 201 lb 8/3/2012 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 1/27/2012 72 Male 174 lb 8/6/2012 Physician Germany
Primary
Concomitant
Hypoglycaemia Hospitalization 12/25/2011 8/7/2012 Consumer Germany
Primary
Secondary
Concomitant
Encephalopathy Life Threatening 3/5/2012 58 Male 268 lb 8/8/2012 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 6/10/2012 62 Female 8/8/2012 Physician Italy
Primary
Concomitant
Interacting
Heart Rate Irregular Other Serious 1/1/2008 Male 7/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/19/2012 65 Female 8/9/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Blood Sodium Increased Life Threatening 7/27/2012 60 Female 8/9/2012 Other Health Professional Italy
Primary
Concomitant
Colon Cancer Other Serious 10/2/2011 8/9/2012 Physician Singapore
Primary
Secondary
Concomitant
Angioedema Hospitalization 8/8/2012 Other Health Professional United States
Primary
Secondary
Fall Hospitalization 7/19/2012 65 Female 8/9/2012 Physician Italy
Primary
Secondary
Concomitant

Drug Data