Bisoprolol Fumarate combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Melaena Hospitalization 12/11/2003 77 Female 1/24/2006 Other Health Professional France
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 39 Female 265 lb 3/22/2006 Physician France
Primary
Secondary
Surgical Procedure Repeated Hospitalization 1/1/1999 62 Male 3/29/2006 Physician Czech Republic
Primary
Concomitant
Renal Failure Other Serious 4/16/2006 70 Male 8/21/2006 Other Health Professional Denmark
Primary
Concomitant
Road Traffic Accident Life Threatening 86 Male 8/31/2006 Germany
Primary
Concomitant
Transaminases Increased Other Serious 74 Male 9/14/2006 Physician Germany
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 7/12/2006 Male 154 lb 9/21/2006 Physician France
Primary
Concomitant
Spondylolysis Other Serious 59 Male 240 lb 9/19/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/17/2006 68 Male 9/27/2006 Pharmacist Canada
Primary
Concomitant
Spondylolysis Other Serious 59 Male 240 lb 9/22/2006 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Unevaluable Event Other Serious 59 Male 240 lb 10/5/2006 United States
Primary
Secondary
Concomitant
Deafness Unilateral Disability 8/19/2006 63 Male 10/10/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 1/1/2005 71 Male 159 lb 10/27/2006 Physician France
Primary
Secondary
Concomitant
Treatment Noncompliance Life Threatening 1/23/2006 71 Male 187 lb 11/1/2006 Physician Germany
Primary
Concomitant
Urinary Retention Death 10/14/2006 69 Female 11/27/2006 Other Health Professional Sweden
Primary
Concomitant
Pleural Effusion Death 9/29/2006 81 Female 143 lb 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Shock Life Threatening 7/5/2005 77 Male 12/26/2006 Consumer Germany
Primary
Secondary
Concomitant
Death Other Serious 12/16/2006 Male 187 lb 1/11/2007 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/17/2006 68 Male 1/15/2007 Pharmacist Canada
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 46 Female 197 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mood Altered Other Serious 1/1/2002 Male 2/13/2007 Physician Germany
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Death 1/15/2007 80 Male 4/3/2007 France
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 3/2/2007 74 Male 4/13/2007 France
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/24/2007 72 Male 152 lb 5/11/2007 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Relapsing Hospitalization 4/21/2007 71 Male 229 lb 5/15/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2006 71 Male 229 lb 5/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 6/1/2006 71 Male 229 lb 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Increased Upper Airway Secretion Other Serious 1/1/2007 Male 195 lb 6/1/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2006 71 Male 229 lb 6/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 11/28/2006 61 Female 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 3/9/2007 85 Female 6/25/2007 France
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 9/25/2006 77 Male 7/6/2007 Other Health Professional France
Primary
Concomitant
Death Death 7/4/2007 Male 137 lb 7/23/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 7/1/2007 67 Male 8/3/2007 Physician Germany
Primary
Concomitant
Malaise Hospitalization 5/1/2007 55 Female 8/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/8/2007 61 Male 9/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 7/23/2007 77 Male 203 lb 10/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Deafness Unilateral Other Serious 8/19/2007 63 Male 10/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Deafness Unilateral Disability 8/19/2006 63 Male 10/12/2007 United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 73 Male 10/22/2007 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 73 Male 10/19/2007 United Kingdom
Primary
Concomitant
Deafness Unilateral Other Serious 8/19/2006 63 Male 10/22/2007 United Kingdom
Primary
Concomitant
Pallor Other Serious 9/19/2007 69 Male 11/5/2007 Other Health Professional Germany
Primary
Concomitant
Pallor Life Threatening 9/19/2007 69 Male 194 lb 11/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/26/2007 Physician United Kingdom
Primary
Concomitant
Tachyarrhythmia Hospitalization 10/9/2007 65 Male 11/27/2007 Physician France
Primary
Secondary
Concomitant
Hypothermia Hospitalization 11/1/2007 77 Male 11/28/2007 Other Health Professional France
Primary
Concomitant
Pallor Life Threatening 9/19/2007 69 Male 11/20/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2007 24 Female 243 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 4/24/2007 72 Male 152 lb 12/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 5/5/2007 81 Male 12/21/2007 Germany
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2007 48 Male 328 lb 1/17/2008 Physician United Kingdom
Primary
Concomitant
Ischaemic Cerebral Infarction Other Serious 5/16/2006 66 Female 2/8/2008 Physician Germany
Primary
Concomitant
Dyspnoea Life Threatening 1/5/2008 63 Female 198 lb 2/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 2/4/2008 62 Female 176 lb 3/1/2008 Consumer Brazil
Primary
Concomitant
Coronary Artery Insufficiency Death 2/18/2008 Female 214 lb 3/4/2008 Physician Russian Federation
Primary
Concomitant
Sepsis Hospitalization 1/28/2008 69 Female 3/12/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Palpitations Hospitalization 1/3/2008 46 Female 216 lb 3/19/2008 Consumer United Kingdom
Primary
Concomitant
Vomiting Life Threatening 3/6/2008 Female 222 lb 3/18/2008 Physician Germany
Primary
Concomitant
Skin Ulcer Hospitalization 2/20/2008 Male 266 lb 4/4/2008 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 65 Male 163 lb 4/4/2008 Consumer Germany
Primary
Concomitant
Vasculitis Hospitalization 12/28/2007 57 Male 4/10/2008 Germany
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/16/2007 79 Male 4/16/2008 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/1/2008 Male 198 lb 4/22/2008 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 4/22/2008 Physician Canada
Primary
Concomitant
Coronary Artery Bypass Other Serious 7/1/2007 Male 4/24/2008 Consumer Brazil
Primary
Concomitant
Skin Ulcer Hospitalization 2/20/2008 Male 266 lb 4/29/2008 Consumer United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2007 48 Male 315 lb 5/2/2008 Physician United Kingdom
Primary
Concomitant
Bradycardia Hospitalization 11/29/2007 Female 196 lb 5/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 5/13/2008 Physician Canada
Primary
Concomitant
Vomiting Other Serious 3/1/2008 Female 222 lb 5/12/2008 Physician Germany
Primary
Concomitant
Tachycardia Death 1/28/2008 75 Female 134 lb 5/5/2008 Physician Canada
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 5/16/2008 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 4/7/2008 78 Male 198 lb 5/21/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/20/2008 Male 266 lb 5/22/2008 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/28/2007 57 Male 5/16/2008 Germany
Primary
Concomitant
Bradycardia Hospitalization 11/29/2007 Female 196 lb 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/28/2007 57 Male 6/2/2008 Germany
Primary
Concomitant
Renal Failure Life Threatening 4/26/2008 72 Male 5/29/2008 France
Primary
Secondary
Radius Fracture Hospitalization 12/10/2007 Female 135 lb 6/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Fatigue Death 5/28/2008 Female 222 lb 6/27/2008 Consumer Ireland
Primary
Concomitant
Restlessness Hospitalization 3/21/2008 66 Female 6/23/2008 Germany
Primary
Secondary
Concomitant
Helicobacter Infection Other Serious 67 Male 209 lb 6/27/2008 Physician Switzerland
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 4/21/2008 Female 207 lb 7/7/2008 Consumer United Kingdom
Primary
Concomitant
Hypersensitivity Hospitalization 70 Female 7/7/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/1/2007 72 Female 7/9/2008 Physician Australia
Primary
Concomitant
Weight Loss Poor Other Serious 7/11/2002 45 Female 7/9/2008 United Kingdom
Primary
Concomitant
Myalgia Other Serious 3/19/2008 65 Male 165 lb 8/4/2008 Physician Germany
Primary
Concomitant
Nausea Other Serious 1/1/2007 48 Male 315 lb 8/11/2008 Physician United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 2/20/2008 Male 266 lb 8/12/2008 Consumer United Kingdom
Primary
Concomitant
Agranulocytosis Life Threatening 4/7/2008 58 Male 8/14/2008
Primary
Secondary
Concomitant
Haematoma Other Serious 8/3/2008 Male 8/29/2008 Pharmacist Switzerland
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 2/1/2008 Female 203 lb 9/3/2008 Physician Germany
Primary
Concomitant
Medication Residue Other Serious 6/1/2008 Male 9/15/2008 Canada
Primary
Concomitant
Vasculitis Other Serious 2/1/2008 60 Female 9/19/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Organic Erectile Dysfunction Hospitalization 1/1/2007 75 Male 9/24/2008 Other Health Professional France
Primary
Concomitant
Infarction Life Threatening 3/16/2008 Female 320 lb 10/1/2008 Consumer United Kingdom
Primary
Concomitant
Death Death Female 10/20/2008 Physician France
Primary
Concomitant
Rhabdomyolysis Death 4/9/2006 69 Female 10/22/2008 Denmark
Primary
Concomitant
Seroma Other Serious 7/15/2008 80 Male 11/6/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/1/2008 Male 11/1/2008 Physician Italy
Primary
Concomitant
Hypertension Hospitalization 12/10/2007 53 Female 11/3/2008 Spain
Primary
Secondary
Concomitant
Presyncope Hospitalization 1/1/2008 Male 11/15/2008 Physician Italy
Primary
Concomitant
Seroma Other Serious 7/15/2008 80 Male 11/19/2008 Physician Germany
Primary
Concomitant
Pancreatitis Other Serious 1/1/2008 Male 187 lb 11/18/2008 Physician Germany
Primary
Concomitant
Acute Coronary Syndrome Hospitalization Female 11/24/2008 Belgium
Primary
Concomitant
Transaminases Increased Other Serious 11/1/2008 60 Male 198 lb 12/1/2008 Other Health Professional Germany
Primary
Concomitant
Somnolence Hospitalization 7/1/2008 70 Female 143 lb 12/2/2008 Physician Germany
Primary
Concomitant
Melaena Hospitalization 12/11/2003 77 Female 12/12/2008 France
Primary
Secondary
Myocardial Infarction Death 3/14/2008 Female 148 lb 12/17/2008 Physician Canada
Primary
Concomitant
Pneumonia Hospitalization 11/17/2008 69 Female 159 lb 12/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Bradycardia Hospitalization 5/30/2008 78 Male 12/17/2008 Switzerland
Primary
Secondary
Concomitant
Microcytic Anaemia Other Serious 4/1/2008 73 Female 12/23/2008 United Kingdom
Primary
Concomitant
Fatigue Death 5/28/2008 Female 222 lb 1/2/2009 Consumer Ireland
Primary
Concomitant
Hypertension Hospitalization 5/30/2008 78 Male 12/17/2008 Switzerland
Primary
Secondary
Concomitant
Postoperative Wound Infection Other Serious 11/25/2008 67 Male 176 lb 1/6/2009 Consumer Israel
Primary
Concomitant
Hypochromic Anaemia Other Serious 4/1/2008 73 Female 1/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Life Threatening 5/26/2008 66 Male 1/16/2009 Germany
Primary
Secondary
Concomitant
Pancreatitis Other Serious 10/27/2008 Male 187 lb 2/10/2009 Physician Germany
Primary
Concomitant
Drug Interaction Other Serious 56 Female 176 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 1/14/2009 76 Male 2/10/2009 Belgium
Primary
Secondary
Concomitant
Aortic Aneurysm Hospitalization 1/14/2009 76 Male 2/26/2009 Belgium
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 1/14/2009 76 Male 2/27/2009 Belgium
Primary
Secondary
Concomitant
Aortic Aneurysm Hospitalization 1/14/2009 76 Male 3/9/2009 Physician Belgium
Primary
Secondary
Concomitant
Nausea Life Threatening 6/2/2008 71 3/20/2009 Germany
Primary
Secondary
Concomitant
Aortic Aneurysm Hospitalization 1/14/2009 76 Male 4/2/2009 Belgium
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/1/2009 Male 220 lb 4/9/2009 Consumer United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 11/17/1998 51 Female 172 lb 4/10/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/30/2008 Male 4/10/2009 Physician Germany
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/1/2009 Male 220 lb 4/29/2009 Consumer United Kingdom
Primary
Concomitant
Vertigo Other Serious 1/1/2009 Male 256 lb 4/29/2009 Physician Germany
Primary
Concomitant
Acute Coronary Syndrome Required Intervention Male United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization 61 Male 4/30/2009 Other Health Professional United States
Primary
Secondary
Mental Disorder Hospitalization 61 Male 5/1/2009 Consumer United States
Primary
Secondary
Homicidal Ideation Other Serious 4/3/2009 45 Male 5/6/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 3/1/2009 70 Female 5/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 4/21/2009 Female 5/6/2009 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious 3/1/2009 70 Female 5/6/2009 Physician Germany
Primary
Secondary
Concomitant
Presyncope Other Serious 1/1/2008 Male 5/18/2009 Physician Italy
Primary
Concomitant
Transaminases Increased Hospitalization 3/7/2009 64 Female 141 lb 5/12/2009 Physician Germany
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 4/29/2009 Male 198 lb 5/11/2009 Physician Germany
Primary
Secondary

Drug Data