Bisoprolol Fumarate combined with Marcumar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mucosal Inflammation Hospitalization 5/12/2006 61 Female 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious Female 132 lb 6/22/2006 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 1/23/2006 71 Male 187 lb 8/24/2006 Physician Germany
Primary
Concomitant
Vaginal Inflammation Other Serious 7/11/2006 68 Female 8/31/2006 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 3/28/2006 73 Male 165 lb 9/1/2006 Physician Germany
Primary
Concomitant
Tendon Rupture Hospitalization 6/1/2006 Female 126 lb 10/11/2006 Physician Germany
Primary
Secondary
Concomitant
Rheumatoid Nodule Hospitalization 4/1/2005 Female 10/18/2006 Consumer Germany
Primary
Concomitant
Rheumatoid Nodule Hospitalization 1/1/2005 Female 10/26/2006 Physician Germany
Primary
Concomitant
Treatment Noncompliance Life Threatening 1/23/2006 71 Male 187 lb 11/1/2006 Physician Germany
Primary
Concomitant
Cardiogenic Shock Death 10/7/2006 59 Male 10/30/2006 Brazil
Primary
Concomitant
Traumatic Brain Injury Death 80 Male 187 lb 12/15/2006 Physician Germany
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/12/2006 61 Female 12/14/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 9/8/2006 61 Male 1/11/2007 Physician Germany
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/9/2006 73 Male 183 lb 1/19/2007 Physician Germany
Primary
Concomitant
Lymphoedema Hospitalization 10/1/2006 77 Female 3/14/2007 Germany
Primary
Concomitant
Ventricular Fibrillation Hospitalization 12/4/2006 Female 198 lb 6/15/2007 Physician Germany
Primary
Secondary
Concomitant
Metabolic Disorder Hospitalization 5/1/2006 Female 154 lb 6/21/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2007 70 Male 176 lb 11/20/2007 Physician Switzerland
Primary
Concomitant
Interacting
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2007 70 Male 176 lb 11/20/2007 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/17/2007 73 Male 1/25/2008 Physician Switzerland
Primary
Concomitant
Interacting
Stevens-johnson Syndrome Hospitalization 8/4/2003 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/3/2008 Female 1/29/2008 Physician Germany
Primary
Concomitant
Vomiting Life Threatening 3/6/2008 Female 222 lb 3/18/2008 Physician Germany
Primary
Concomitant
Weight Increased Disability 1/1/2007 70 Male 251 lb 4/14/2008 Pharmacist Germany
Primary
Concomitant
Skin Toxicity Hospitalization Male 181 lb 5/7/2008 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 70 Male 256 lb 5/8/2008 Pharmacist Germany
Primary
Concomitant
Skin Toxicity Hospitalization 3/1/2008 Male 181 lb 5/8/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 3/1/2008 Female 222 lb 5/12/2008 Physician Germany
Primary
Concomitant
Skin Toxicity Hospitalization 3/1/2008 Male 181 lb 5/23/2008 Physician Germany
Primary
Concomitant
Tachyarrhythmia Life Threatening 7/2/2008 Female 284 lb 7/28/2008 Physician Germany
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization 55 Male 10/1/2008 Physician Germany
Primary
Concomitant
Dry Mouth Other Serious 6/1/2008 76 Male 12/1/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 6/15/2008 Male 212 lb 12/12/2008 Other Health Professional Germany
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/16/2006 Female 12/16/2008 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/16/2006 Female 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization 55 Male 1/8/2009 Physician Germany
Primary
Concomitant
Prothrombin Time Shortened Other Serious 10/1/2008 Male 2/6/2009 Consumer Germany
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 6/24/2008 Female 284 lb 3/26/2009 Physician Germany
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 10/27/2008 72 Male 258 lb 3/31/2009 Other Health Professional Germany
Primary
Secondary
Interacting
Vertigo Other Serious 2/16/2009 Male 192 lb 4/13/2009 Physician Germany
Primary
Concomitant
Pain In Extremity 11/1/2007 5/4/2009 Physician Germany
Primary
Concomitant
Blood Lactic Acid Increased Death 3/2/2009 55 Male 5/11/2009 Physician Switzerland
Primary
Secondary
Concomitant
Mechanical Complication Of Implant Hospitalization 5/26/2009 52 Male 7/31/2009 Austria
Primary
Concomitant
Surgery Hospitalization 5/26/2009 52 Male 8/11/2009 Austria
Primary
Concomitant
Cardioversion Hospitalization 1/1/2009 Female 201 lb 8/14/2009 Germany
Primary
Concomitant
Tachycardia Hospitalization 9/1/2008 78 Female 130 lb 10/2/2009 Physician Belgium
Primary
Concomitant
Syncope Life Threatening 3/5/2009 89 Male 12/1/2009 Physician Germany
Primary
Concomitant
Urosepsis Life Threatening 10/14/2009 Female 123 lb 1/14/2010 Physician Germany
Primary
Concomitant
Sudden Cardiac Death Death 1/18/2010 75 Male 176 lb 3/1/2010 Physician Germany
Primary
Concomitant
Muscle Spasms Life Threatening 12/1/2009 70 Male 192 lb 2/23/2010 Germany
Primary
Concomitant
Sudden Cardiac Death Death 1/18/2010 75 Male 176 lb 3/5/2010 Physician Germany
Primary
Concomitant
Sudden Cardiac Death Death 1/18/2010 75 Male 176 lb 3/5/2010 Physician Germany
Primary
Concomitant
Bronchial Hyperreactivity Other Serious 11/1/2009 76 Male 4/12/2010 Germany
Primary
Concomitant
Thrombocytopenia Death 3/9/2010 84 Female 137 lb 4/29/2010 Other Health Professional Germany
Primary
Concomitant
Prothrombin Time Abnormal Hospitalization 1/1/2010 Female 5/3/2010 Physician Germany
Primary
Concomitant
Interacting
Osteoporotic Fracture Hospitalization 5/26/2010 81 Female 198 lb 6/30/2010
Primary
Concomitant
Microcytic Anaemia Life Threatening 1/1/2009 70 Male 192 lb 7/22/2010 Germany
Primary
Concomitant
Sudden Cardiac Death Hospitalization 1/3/2010 77 Male 8/30/2010 Physician Germany
Primary
Concomitant
Muscle Spasms Life Threatening 1/1/2009 70 Male 192 lb 9/1/2010 Physician Germany
Primary
Concomitant
Skin Ulcer Hospitalization 6/23/2010 85 Female 203 lb 9/27/2010 Physician Germany
Primary
Concomitant
Presyncope Hospitalization 8/17/2010 71 Male 231 lb 10/29/2010 Physician Germany
Primary
Concomitant
Pulse Absent Hospitalization 6/23/2010 85 Female 203 lb 11/18/2010 Physician Germany
Primary
Concomitant
Myocardial Infarction Life Threatening 3/14/2010 77 Female 168 lb 11/22/2010 Physician Germany
Primary
Concomitant
Oedema Peripheral Disability 7/15/2010 79 Female 176 lb 11/29/2010 Physician Germany
Primary
Concomitant
Pancreatitis Other Serious 1/18/2011 82 Female 149 lb 2/24/2011 Physician Germany
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 12/27/2010 70 Female 194 lb 2/25/2011 Physician Germany
Primary
Concomitant
Interacting
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 85 Female 203 lb 2/28/2011 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 11/1/2007 66 Male 134 lb 3/3/2011 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 7/20/2010 69 Female 104 lb 3/4/2011 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 11/1/2010 60 Male 176 lb 4/5/2011 Physician Germany
Primary
Concomitant
Haemangioma Other Serious 12/1/2008 62 Female 4/20/2011 Physician Germany
Primary
Concomitant
Abdominal Pain Hospitalization 1/1/2011 76 Female 4/13/2011 Physician Switzerland
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization Male 5/4/2011 Consumer Germany
Primary
Concomitant
Anaemia Other Serious 4/14/2011 77 Male 187 lb 5/17/2011 Physician Germany
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2011 76 Female 5/6/2011 Physician Switzerland
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/1/2011 73 Female 126 lb 5/19/2011 Physician France
Primary
Concomitant
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 5/26/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Jaundice Other Serious 4/1/2011 71 Female 5/27/2011 Physician Germany
Primary
Concomitant
Drug Eruption Hospitalization 3/1/2011 Female 159 lb 5/27/2011 Physician Germany
Primary
Concomitant
Cerebral Haemorrhage Hospitalization Male 6/2/2011 Consumer Germany
Primary
Concomitant
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 6/7/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Interaction Life Threatening 11/8/2010 80 Female 5/24/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 11/8/2010 80 Female 6/7/2011 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Death 3/1/2009 78 Female 6/10/2011 Switzerland
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 6/23/2010 85 Female 203 lb 6/29/2011 Physician Germany
Primary
Concomitant
Drug Eruption Hospitalization 3/1/2011 Female 159 lb 6/29/2011 Physician Germany
Primary
Concomitant
Generalised Oedema Life Threatening 1/1/2011 70 Male 6/29/2011 Consumer Germany
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 11/9/2009 66 Male 168 lb 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Skin Fissures Disability 1/1/2010 66 Male 165 lb 7/25/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 72 Male 7/28/2011 Consumer Germany
Primary
Concomitant
Lung Disorder Other Serious 3/15/2011 73 Female 126 lb 8/1/2011 Physician France
Primary
Concomitant
Lung Disorder Hospitalization 1/1/2010 66 Male 7/29/2011 Physician Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization Male 8/2/2011 Consumer Germany
Primary
Concomitant
Decreased Appetite Hospitalization 12/24/2010 63 Female 154 lb 8/5/2011 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 8/18/2010 77 Male 8/9/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2011 74 Female 198 lb 8/8/2011 Physician Germany
Primary
Concomitant
Hypersensitivity Other Serious 1/1/2011 74 Female 198 lb 8/16/2011 Physician Germany
Primary
Concomitant
Cardiac Death Death 5/19/2011 70 Male 187 lb 8/16/2011 Physician Netherlands
Primary
Concomitant
Cardiac Failure Hospitalization 5/4/2011 76 Male 194 lb 8/19/2011 Physician Germany
Primary
Concomitant
Endotracheal Intubation Hospitalization 6/4/2011 73 Female 119 lb 8/25/2011 Pharmacist Germany
Primary
Concomitant
Anaemia Hospitalization 8/1/2011 Female 8/31/2011 Consumer Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 7/19/2011 86 Female 9/6/2011 Physician Switzerland
Primary
Concomitant
Interacting
Eating Disorder Hospitalization 8/24/2011 72 Female 9/8/2011 Consumer Germany
Primary
Concomitant
Cholestatic Liver Injury Hospitalization 7/8/2011 78 Male 9/19/2011 Physician Switzerland
Primary
Secondary
Concomitant
Tooth Disorder Disability 5/1/2011 83 Male 187 lb 9/22/2011 Consumer Switzerland
Primary
Concomitant
Cholestatic Liver Injury Hospitalization 7/8/2011 78 Male 9/22/2011 Physician Switzerland
Primary
Secondary
Concomitant
Coagulopathy Other Serious 5/30/2011 69 Male 293 lb 9/26/2011 Pharmacist Germany
Primary
Secondary
Thrombocytopenia Hospitalization 11/4/2010 80 Female 159 lb 9/26/2011 Other Health Professional Germany
Primary
Concomitant
Impaired Healing Hospitalization 10/6/2010 66 Male 220 lb 11/23/2011 Germany
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 10/1/2011 78 Male 159 lb 11/28/2011 Physician Germany
Primary
Concomitant
Dysgeusia Other Serious 10/1/2011 78 Male 159 lb 11/28/2011 Physician Germany
Primary
Concomitant
Atrial Fibrillation Other Serious 69 Male 11/30/2011 Consumer Germany
Primary
Concomitant
Atrial Fibrillation Other Serious 1/4/2011 61 Female 203 lb 12/16/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Death 73 Male 236 lb 12/21/2011 Germany
Primary
Concomitant
Drug Ineffective Death 1/1/2011 86 Female 12/27/2011 Physician Switzerland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Death 1/1/2011 86 Female 12/28/2011 Physician Switzerland
Primary
Secondary
Concomitant
Brain Natriuretic Peptide Increased Other Serious 1/1/2011 Male 1/5/2012 Consumer Austria
Primary
Concomitant
Gastric Ulcer Death Female 1/5/2012 Physician Switzerland
Primary
Secondary
Concomitant
Brain Natriuretic Peptide Increased Other Serious 1/1/2011 61 Male 1/6/2012 Consumer Austria
Primary
Concomitant
Decreased Activity Other Serious 1/1/2011 61 Male 1/10/2012 Consumer Austria
Primary
Concomitant
Suicide Attempt Hospitalization 1/1/2011 51 Male 1/5/2012 Physician Germany
Primary
Secondary
Thrombocytopenia Death 9/10/2011 86 Female 1/17/2012 Physician Switzerland
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Hospitalization Male 1/17/2012 Physician Germany
Primary
Secondary
Influenza Like Illness Life Threatening 1/20/2011 58 Male 205 lb 1/18/2012 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Death 8/12/2011 86 Female 1/23/2012 Physician Switzerland
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 1/1/2011 51 Male 1/19/2012 Physician Germany
Primary
Secondary
Abdominal Pain Hospitalization 12/18/2011 65 Female 2/15/2012 Physician Germany
Primary
Concomitant
Drug Ineffective Hospitalization 12/1/2011 82 Male 181 lb 2/16/2012 Physician Germany
Primary
Secondary
Concomitant
Creatinine Urine Increased Death 1/3/2011 74 Male 306 lb 2/23/2012 Physician Germany
Primary
Concomitant
Pericardial Haemorrhage Life Threatening 11/30/2011 76 Female 164 lb 2/27/2012 Physician Germany
Primary
Concomitant
Angina Pectoris Hospitalization 6/29/2010 Female 172 lb 3/1/2012 Physician Germany
Primary
Concomitant
Fatigue Other Serious 9/18/2011 Male 176 lb 3/7/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 1/1/2007 68 3/9/2012 Physician Germany
Primary
Concomitant
Thrombosis Death 2/3/2011 73 Male 143 lb 3/16/2012 Physician Germany
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 2/21/2012 74 Male 228 lb 3/16/2012 Other Health Professional Austria
Primary
Concomitant
General Physical Health Deterioration Life Threatening 11/30/2011 76 Female 164 lb 3/16/2012 Physician Germany
Primary
Concomitant
Urinary Tract Infection Life Threatening 12/12/2011 76 Female 164 lb 3/19/2012 Physician Germany
Primary
Concomitant
Bladder Transitional Cell Carcinoma Hospitalization 10/3/2011 80 190 lb 3/20/2012 Physician
Primary
Concomitant
General Physical Health Deterioration Life Threatening 12/12/2011 76 Female 164 lb 3/20/2012 Physician Germany
Primary
Concomitant
Rash Hospitalization 3/1/2011 Female 159 lb 3/21/2012 Physician Germany
Primary
Concomitant
Monoclonal Gammopathy Death 1/3/2011 74 Male 306 lb 3/21/2012 Physician Germany
Primary
Concomitant
Bladder Transitional Cell Carcinoma Hospitalization 10/3/2011 80 Male 190 lb 3/21/2012 Physician
Primary
Concomitant
Renal Failure Acute Hospitalization 1/2/2012 70 Female 108 lb 3/23/2012 Physician Switzerland
Primary
Secondary
Concomitant
Pericardial Haemorrhage Life Threatening 12/12/2011 76 Female 164 lb 3/23/2012 Physician Germany
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 1/1/2007 68 3/23/2012 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Other Serious 9/18/2011 Male 176 lb 3/23/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 2/15/2012 73 Male 174 lb 3/26/2012 Physician Germany
Primary
Secondary
Concomitant
Proteinuria Hospitalization 1/2/2012 70 Female 108 lb 4/2/2012 Physician Switzerland
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 2/21/2012 74 Male 228 lb 4/2/2012 Other Health Professional Austria
Primary
Concomitant
Blood Creatine Increased Other Serious 1/1/2011 77 Female 132 lb 4/3/2012 Physician Belgium
Primary
Concomitant

Drug Data