Bisoprolol Fumarate combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 12/12/2005 70 Female 1/13/2006 France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization Female 2/16/2006 Ireland
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 1/2/2006 78 Female 2/24/2006 France
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/20/2005 56 Female 187 lb 4/11/2006 Physician Poland
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/20/2005 56 Female 187 lb 4/20/2006 Physician Poland
Primary
Secondary
Concomitant
Coma Hospitalization 60 Female 176 lb 4/20/2006 Physician Belgium
Primary
Concomitant
Bundle Branch Block Right Hospitalization 4/26/2006 69 Male 225 lb 5/22/2006 Other Health Professional Germany
Primary
Concomitant
Pruritus Other Serious 11/1/2005 60 Female 207 lb 5/26/2006 Physician Slovenia
Primary
Concomitant
Rheumatoid Nodule Hospitalization 49 Female 6/9/2006 Physician Austria
Primary
Concomitant
Dyspnoea Hospitalization 10/20/2005 56 Female 187 lb 6/14/2006 Physician Poland
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 1/30/2006 78 Female 6/19/2006 Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/2/2005 71 Male 216 lb 6/27/2006 Other Health Professional Germany
Primary
Concomitant
Heart Rate Increased Other Serious Female 132 lb 6/22/2006 Physician Germany
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 2/23/2006 77 Female 6/23/2006 Physician United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 2/23/2006 77 Female 6/27/2006 Physician United Kingdom
Primary
Concomitant
Intracranial Pressure Increased Life Threatening 10/1/2005 64 Male 7/10/2006 Norway
Primary
Secondary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Peripheral Nerve Injury Other Serious 7/11/2006 63 Female 7/21/2006 France
Primary
Concomitant
Intracranial Pressure Increased Life Threatening 10/1/2005 64 Male 7/27/2006 Norway
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2006 Female 143 lb 8/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 10/1/2005 65 Male 8/11/2006 Germany
Primary
Concomitant
Pulmonary Oedema Other Serious 9/4/2003 57 Female 8/21/2006 United States
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly 1/1/2005 Male 8/15/2006 France
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 1/1/2005 Male 8/17/2006 France
Primary
Secondary
Ischaemic Stroke Life Threatening 5/29/2006 86 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/30/2006 52 Female 176 lb 9/6/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2005 74 Male 198 lb 9/22/2006 Other Health Professional Germany
Primary
Concomitant
Aortic Valve Incompetence Required Intervention 6/8/2005 12 Male 9/22/2006 Physician United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 7/3/2006 76 Male 10/3/2006 France
Primary
Concomitant
Status Epilepticus Other Serious 4/3/2006 60 Female 176 lb 9/25/2006 Physician Belgium
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 9/14/2006 84 Female 10/5/2006 France
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 70 Female 10/16/2006 Consumer Sweden
Primary
Concomitant
Rash Hospitalization 1/1/2005 65 Female 10/17/2006 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2005 80 Female 11/8/2006 Physician Germany
Primary
Concomitant
Myocardial Ischaemia Death Female 126 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2005 65 Female 180 lb 11/1/2006 United States
Primary
Concomitant
Therapy Cessation Hospitalization 10/19/2006 67 Male 122 lb 11/3/2006 Physician United Kingdom
Primary
Concomitant
Synovitis Other Serious 9/4/2003 57 Female 11/17/2006 United States
Primary
Concomitant
Joint Dislocation Hospitalization 6/30/2006 Female 121 lb 11/17/2006 Physician United Kingdom
Primary
Concomitant
Hypoaesthesia Oral Hospitalization Female 98 lb 11/22/2006 Physician Germany
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Dislocation Of Vertebra Hospitalization 6/30/2006 Female 132 lb 11/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Column Stenosis Other Serious 1/1/2002 68 Male 181 lb 11/27/2006 Physician Germany
Primary
Concomitant
Stomatitis Hospitalization 10/18/2006 67 Male 122 lb 12/4/2006 Physician United Kingdom
Primary
Concomitant
Hormone Level Abnormal Hospitalization 3/22/2005 Female 137 lb 12/14/2006 Consumer United Kingdom
Primary
Concomitant
Tinnitus Hospitalization 9/10/2005 Female 172 lb 12/28/2006 Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2005 80 Female 1/5/2007 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/30/2006 Female 132 lb 1/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Stomatitis Hospitalization 10/18/2006 Male 122 lb 2/1/2007 United Kingdom
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 5/17/2005 Female 112 lb 2/6/2007 Italy
Primary
Concomitant
Myalgia Disability 1/19/2007 80 2/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Gastrointestinal Angiodysplasia Haemorrhagic Hospitalization 11/23/2006 77 Female 170 lb 1/30/2007 Physician France
Primary
Concomitant
Spinal Column Stenosis Other Serious 1/1/2002 Male 181 lb 2/16/2007 Physician Germany
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2006 47 Female 148 lb 2/19/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 Female 2/27/2007 Physician Germany
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2006 47 Female 148 lb 2/19/2007 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 91 Male 2/26/2007 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/1/2007 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 2/21/2007 71 Female 4/3/2007 France
Primary
Concomitant
Rash Pruritic Hospitalization 3/24/2007 75 Male 4/25/2007 United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 4/26/2007 United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/26/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/28/2007 United Kingdom
Primary
Secondary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 3/1/2006 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/21/2007 71 Female 5/16/2007 France
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 7/13/2006 Male 159 lb 5/25/2007 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 5/29/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Somnolence Hospitalization 9/2/2006 53 Female 6/1/2007 Other Health Professional France
Primary
Concomitant
Plasmacytoma Other Serious 10/26/2006 Male 185 lb 6/8/2007 France
Primary
Concomitant
Plasmacytoma Other Serious 10/26/2006 Male 185 lb 6/15/2007 France
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 5/31/2007 United Kingdom
Primary
Concomitant
Restless Legs Syndrome Other Serious 4/24/2007 62 Female 146 lb 6/11/2007 Physician Germany
Primary
Concomitant
Jaundice Other Serious 5/1/2007 55 Female 163 lb 6/29/2007 Physician Chile
Primary
Concomitant
Hypertension Life Threatening 6/5/2007 68 Female 7/18/2007 Physician Germany
Primary
Concomitant
Renal Failure Female 7/26/2007 Pharmacist United States
Primary
Secondary
Muscular Weakness Disability 1/19/2007 80 7/6/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2006 66 Female 8/3/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Thrombocytopenia Death 7/19/2007 Female 9/6/2007 Physician Italy
Primary
Concomitant
Psoriasis Other Serious 3/1/2007 47 Female 148 lb 9/11/2007 Other Health Professional Switzerland
Primary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/10/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/12/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/15/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/17/2007 75 Female 194 lb 10/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Progesterone Receptor Assay Positive Other Serious 2/8/2007 74 Female 10/8/2007 Physician France
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2002 40 Female 10/15/2007 Other Health Professional Denmark
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 72 Male 10/18/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Pancytopenia Other Serious 80 Female 10/18/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 73 Female 10/19/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 10/24/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 65 Female 10/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Perforation Death 10/3/2007 Female 134 lb 10/29/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Small Intestinal Perforation Death 10/3/2007 Female 134 lb 11/2/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 8/17/2007 71 Female 10/29/2007 France
Primary
Secondary
Concomitant
Bundle Branch Block Right Hospitalization 4/26/2006 Male 225 lb 11/6/2007 Germany
Primary
Concomitant
Bundle Branch Block Right Hospitalization 4/26/2006 Male 225 lb 11/9/2007 Germany
Primary
Concomitant
Pulmonary Hypertension Other Serious 60 Female 11/14/2007 Consumer United Kingdom
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/17/2007 75 Female 194 lb 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2007 85 Male 11/20/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tremor Hospitalization 10/9/2007 Female 11/15/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 10/9/2007 11/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 10/9/2007 Female 11/28/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Septic Shock Hospitalization 8/15/2007 Female 170 lb 11/29/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2007 24 Female 243 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 10/9/2007 Female 12/7/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 12/19/2007 Germany
Primary
Concomitant
Tendon Rupture Disability 12/25/2006 57 Male 12/13/2007 France
Primary
Secondary
Weight Increased Hospitalization 10/19/2007 65 Female 12/27/2007 Physician United Kingdom
Primary
Concomitant
Headache Other Serious 1/5/2008 Female 150 lb 1/31/2008 Canada
Primary
Concomitant
Rhabdomyolysis Death 12/1/2006 91 Male 1/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 2/5/2008 United Kingdom
Primary
Concomitant
Nausea Other Serious 10/1/2007 75 Female 2/12/2008 Other Health Professional Norway
Primary
Concomitant
Torsade De Pointes Life Threatening 65 Female 2/7/2008 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 2/11/2008 United States
Primary
Concomitant
Nausea Other Serious 1/1/2007 75 Female 2/20/2008 Physician Norway
Primary
Concomitant
Humerus Fracture Other Serious 10/28/2007 Female 253 lb 3/3/2008 Physician Ireland
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 48 Male 201 lb 3/11/2008 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Death 11/25/2006 91 Male 3/8/2008 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 4/7/2008 Physician Germany
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 65 Female 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Papilloma Other Serious 1/26/2007 30 Female 4/28/2008 Physician France
Primary
Concomitant
Drug Interaction Hospitalization Female 4/30/2008 United Kingdom
Primary
Secondary
Concomitant
Bradycardia Hospitalization 11/29/2007 Female 196 lb 5/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Humerus Fracture Other Serious 10/28/2007 Female 253 lb 5/14/2008 Physician Ireland
Primary
Concomitant
Proteinuria Hospitalization 4/23/2007 Female 123 lb 5/14/2008 France
Primary
Concomitant
Loss Of Consciousness Life Threatening 4/16/2008 87 Female 5/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Bradycardia Hospitalization 11/29/2007 Female 196 lb 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 2/1/2008 82 Female 6/3/2008 Ireland
Primary
Concomitant
Sepsis Other Serious 2/28/2008 Male 205 lb 6/9/2008 Germany
Primary
Concomitant
Superinfection Hospitalization 4/1/2008 98 Male 5/26/2008 France
Primary
Secondary
Concomitant
Thrombosis Other Serious 6/13/2008 Physician Germany
Primary
Concomitant
Vomiting Life Threatening 4/15/2008 Female 6/20/2008 Other Health Professional France
Primary
Concomitant
Interacting
Oedema Peripheral Hospitalization 1/19/2007 54 Female 6/24/2008 Physician Germany
Primary
Concomitant
Renal Failure Disability 7/24/2005 59 Male 6/5/2008 France
Primary
Secondary
Gallbladder Cancer Life Threatening 4/30/2008 Male 192 lb 6/27/2008 Physician United Kingdom
Primary
Concomitant
Lactic Acidosis Life Threatening 4/29/2008 Female 6/27/2008 Other Health Professional France
Primary
Concomitant
Interacting
Thrombosis Other Serious 3/7/2008 73 Male 176 lb 6/25/2008 Physician Germany
Primary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 6/30/2008 Germany
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 5/30/2008 87 Female 6/17/2008 France
Primary
Secondary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 7/11/2008 Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/20/2008 Female 7/16/2008 Other Health Professional France
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 7/25/2008 Germany
Primary
Concomitant
Ejection Fraction Decreased Other Serious 10/26/2006 7/28/2008 Consumer France
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/1/2008 56 Female 176 lb 8/4/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 6/16/2008 75 Male 8/6/2008 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/1/2008 56 Female 176 lb 8/7/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 7/29/2008 73 Male 8/4/2008 Physician Germany
Primary
Concomitant

Drug Data