Bisoprolol Fumarate combined with Lactulose

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mucosal Inflammation Hospitalization 5/12/2006 61 Female 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 6/28/2005 72 Male 6/22/2006 Canada
Primary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Ischaemic Stroke Other Serious 7/7/2004 Female 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 8/11/2006 Male 174 lb 9/7/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2005 74 Male 198 lb 9/22/2006 Other Health Professional Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 8/11/2006 Male 174 lb 9/29/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Skin Burning Sensation Hospitalization 12/1/2004 Female 176 lb 10/19/2006 Physician Germany
Primary
Secondary
Transient Ischaemic Attack Other Serious 12/3/2005 78 Female 110 lb 10/18/2006 Other Health Professional Belgium
Primary
Concomitant
Flushing Hospitalization 12/1/2004 73 Female 11/13/2006 Physician Germany
Primary
Secondary
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hormone Level Abnormal Hospitalization 3/22/2005 Female 137 lb 12/14/2006 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/12/2006 61 Female 12/14/2006 Physician Germany
Primary
Secondary
Concomitant
Restlessness 52 Male 11/10/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 9/18/2006 63 Female 4/5/2007 Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2007 67 Male 188 lb 10/3/2007 Physician Germany
Primary
Concomitant
Regurgitation Other Serious 8/28/2007 67 Male 188 lb 10/15/2007 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/23/2007 67 Male 223 lb 10/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/27/2007 10/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 12/19/2007 Germany
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/30/2007 Male 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epistaxis Life Threatening 1/1/2007 76 Male 186 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Iron Deficiency Life Threatening 10/30/2007 76 Male 186 lb 2/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Flushing Hospitalization 12/1/2004 73 Female 2/21/2008 Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 10/18/2007 67 Female 4/15/2008 Physician Ireland
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/18/2007 67 Female 4/21/2008 Physician Ireland
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/18/2007 67 Female 5/7/2008 Physician Ireland
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 67 Female 5/7/2008 Ireland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/19/2007 67 Female 5/21/2008 Ireland
Primary
Secondary
Concomitant
Pain Other Serious 4/25/2008 50 Male 6/5/2008 Physician France
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Renal Failure Hospitalization 4/25/2008 50 Male 5/30/2008 France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/11/2008 Male 6/13/2008 France
Primary
Secondary
Concomitant
Vomiting Other Serious 5/8/2008 76 Female 121 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/11/2008 Male 6/23/2008 France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/25/2008 50 Male 5/30/2008 France
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 7/25/2008 Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 8/9/2008 United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/1/2008 75 Male 161 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2008 76 Female 9/3/2008 Other Health Professional Sweden
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 9/18/2008 Germany
Primary
Concomitant
Oral Pain Life Threatening 8/1/2008 79 Female 9/30/2008 Other Health Professional Germany
Primary
Concomitant
Tachycardia Hospitalization 11/26/2007 65 Male 161 lb 10/12/2008 Physician Japan
Primary
Secondary
Concomitant
Oral Pain Life Threatening 8/1/2008 79 Female 10/16/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Confusional State Death 80 Male 123 lb 10/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 6/8/2007 73 Female 150 lb 10/31/2008 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/20/2008 Male 11/4/2008 Netherlands
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/20/2008 Male 172 lb 11/12/2008 Netherlands
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/18/2008 United Kingdom
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 10/20/2008 Male 172 lb 11/26/2008 Netherlands
Primary
Secondary
Concomitant
Somnolence Hospitalization 10/20/2008 Male 172 lb 12/1/2008 Netherlands
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 10/21/2008 86 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 6/8/2007 73 Female 150 lb 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 4/10/2008 83 Female 12/9/2008 Germany
Primary
Secondary
Concomitant
Oral Pain Life Threatening 8/1/2008 79 Female 12/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 10/8/2008 79 Female 131 lb 12/15/2008
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 12/1/2005 48 Female 12/17/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Shunt Thrombosis Hospitalization 3/11/2008 Male 160 lb 12/23/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/29/2008 Physician Germany
Primary
Secondary
Concomitant
Shunt Thrombosis Hospitalization 5/20/2008 Male 160 lb 1/6/2009 Physician Germany
Primary
Concomitant
Hypoglycaemia Life Threatening 4/1/2008 88 Female 161 lb 3/9/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/26/2009 Germany
Primary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/27/2009 Germany
Primary
Concomitant
Fall Hospitalization 2/19/2009 80 Male 3/26/2009 Physician France
Primary
Secondary
Concomitant
Hypertension Hospitalization 9/15/2004 Female 134 lb 4/14/2009 Germany
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 54 Male 5/7/2009 Physician United Kingdom
Primary
Concomitant
Hypertension Hospitalization 9/15/2004 Female 134 lb 6/5/2009 Germany
Primary
Concomitant
Myalgia Hospitalization 5/29/2009 68 Male 6/26/2009 United Kingdom
Primary
Concomitant
Myalgia Hospitalization 5/29/2009 68 Male 6/29/2009 United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization 5/29/2009 68 Male 6/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myalgia Hospitalization 5/29/2009 68 Male 7/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 6/30/2009 Male 157 lb 7/9/2009 Physician United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 5/29/2009 68 Male 7/10/2009 United Kingdom
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 9/15/2004 Female 134 lb 9/16/2009 Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Clostridial Infection Hospitalization 3/1/2009 90 Female 2/12/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 9/15/2004 Female 134 lb 2/25/2010 Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 8/17/2009 70 Female 150 lb 1/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 3/3/2010 Male 3/10/2010 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 3/1/2010 85 Male 4/8/2010 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/3/2010 57 Male 4/9/2010 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 3/1/2010 85 Male 4/23/2010 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/3/2010 57 Male 5/21/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 3/1/2009 90 Female 8/9/2010 Consumer France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/8/2010 80 Male 8/19/2010 Consumer France
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/28/2010 64 Male 240 lb 9/7/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 154 lb 9/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 9/8/2010 Physician Germany
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 3/1/2009 90 Female 9/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 154 lb 9/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 154 lb 9/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pallor Hospitalization 91 Female 9/27/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 9/24/2010 81 Male 10/19/2010 United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/23/2010 55 Male 12/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/23/2010 55 Male 12/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 10/23/2010 55 Male 12/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 12/23/2010 75 Female 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 12/23/2010 75 Female 2/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 12/23/2010 75 Female 2/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 12/4/2009 71 Male 198 lb 2/24/2011 Physician Germany
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 12/23/2010 74 Female 2/28/2011 Other Health Professional Israel
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 12/23/2010 75 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2011 82 Male 172 lb 3/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Arterial Occlusive Disease Other Serious 1/12/2011 Female 3/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 12/1/2010 82 Female 119 lb 3/14/2011 Physician United Kingdom
Primary
Concomitant
Postrenal Failure Death 3/1/2011 68 Male 163 lb 3/24/2011 Physician France
Primary
Secondary
Concomitant
Medication Error Death Female 4/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 89 Female 4/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 1/9/2008 89 Female 4/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wrong Drug Administered Death 1/9/2008 89 Female 4/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Analysis Abnormal Hospitalization 2/19/2011 61 Male 4/7/2011 Other Health Professional Germany
Primary
Concomitant
Wrong Drug Administered Death 89 Female 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Hospitalization 1/9/2008 89 Female 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Off Label Use Other Serious Female 4/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Medication Error Death 89 Female 4/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Medication Error Death 89 Female 4/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Medication Error Death 89 Female 4/15/2011 United Kingdom
Primary
Secondary
Concomitant
Cough Hospitalization 7/1/2010 75 Female 176 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Fatigue Hospitalization 1/1/2011 82 Male 172 lb 5/4/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Wrong Drug Administered Death Female 5/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Off Label Use Death 89 Female 4/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 1/9/2008 89 Female 5/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wrong Drug Administered Death 89 Female 4/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Hospitalization 3/1/2011 68 Male 163 lb 5/10/2011 Physician France
Primary
Secondary
Concomitant
Drug Administration Error Death 89 Female 4/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Off Label Use Death 1/9/2008 89 Female 5/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Medication Error Death Female 5/16/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 89 Female 5/9/2011 United Kingdom
Primary
Secondary
Concomitant
Cough Hospitalization 7/28/2009 75 Female 176 lb 5/20/2011 Consumer United Kingdom
Primary
Concomitant
Off Label Use Other Serious 89 Female 5/20/2011 United Kingdom
Primary
Secondary
Concomitant
Death Death 2/10/2011 89 Female 7/14/2011 Consumer Switzerland
Primary
Concomitant
Liver Function Test Abnormal Other Serious 7/4/2011 83 Female 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cholestasis Hospitalization 7/4/2011 83 Female 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/6/2011 78 Male 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cholestasis Hospitalization 7/4/2011 83 Female 7/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 5/16/2011 87 Female 138 lb 7/28/2011 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/6/2011 78 Male 7/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/2/2011 78 Male 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data