Bisoprolol Fumarate combined with Hydrochlorothiazide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 1/2/2006 84 Male 3/6/2006 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/2/2006 84 Male 3/8/2006 Belgium
Primary
Secondary
Concomitant
Nausea Other Serious 11/3/2005 77 Female 4/4/2006 Consumer United States
Primary
Secondary
Troponin I Increased Hospitalization 58 Female 119 lb 7/6/2006 Canada
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 3/3/2006 63 Female 6/15/2006 United States
Primary
Concomitant
Syncope Hospitalization 68 Female 7/14/2006 Physician Belgium
Primary
Secondary
Concomitant
Somnolence 6/1/2005 55 Male 7/21/2006 Consumer United States
Primary
Concomitant
Diarrhoea 1/1/2005 77 Female 220 lb 8/1/2006 Consumer United States
Primary
Concomitant
Depression Other Serious 62 Female 152 lb 8/21/2006 Consumer United States
Primary
Concomitant
Migraine With Aura Hospitalization 64 Male 11/15/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 11/6/2006 69 Male 11/28/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 11/6/2006 69 Male 11/30/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Flushing Hospitalization 12/1/2004 73 Female 11/13/2006 Physician Germany
Primary
Secondary
Spinal Disorder Hospitalization 12/13/2006 67 Male 12/21/2006 Consumer Hungary
Primary
Concomitant
Shock Life Threatening 7/5/2005 77 Male 12/26/2006 Consumer Germany
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 11/6/2006 69 Male 1/22/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2000 46 Female 197 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Lung Neoplasm Hospitalization 1/4/2007 65 Male 1/29/2007 Physician Hungary
Primary
Concomitant
Nausea Other Serious 12/1/2004 56 Female 4/11/2007 Consumer Netherlands
Primary
Secondary
Concomitant
Increased Upper Airway Secretion Other Serious 1/1/2007 Male 195 lb 6/1/2007 Physician United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/1/2005 71 Female 6/5/2007 Physician Germany
Primary
Concomitant
Migraine With Aura Hospitalization 64 Male 6/20/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2006 58 Female 134 lb 6/19/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2007 70 Female 6/25/2007 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2007 70 Female 7/11/2007 Belgium
Primary
Secondary
Concomitant
Tremor Other Serious Female 7/27/2007 Consumer Canada
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 6/10/2007 Female 8/3/2007 Physician Bulgaria
Primary
Concomitant
Tongue Oedema Other Serious 7/25/2003 65 Male 218 lb 10/6/2007 Physician United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 59 Male 10/8/2007
Primary
Secondary
Concomitant
Vomiting Other Serious 8/4/2007 Male 176 lb 10/30/2007 Physician Portugal
Primary
Concomitant
Dermatitis Allergic Life Threatening 10/8/2007 Male 163 lb 12/3/2007 Physician Germany
Primary
Concomitant
Vomiting Other Serious 8/4/2007 Male 176 lb 12/13/2007 Physician Portugal
Primary
Concomitant
Vomiting Other Serious 8/4/2007 Male 176 lb 12/26/2007 Physician Portugal
Primary
Concomitant
Intestinal Gangrene Hospitalization 12/13/2007 Male 202 lb 1/10/2008 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 12/5/2007 74 Male 1/24/2008 Other Health Professional Netherlands
Primary
Concomitant
Cardiac Failure Hospitalization 9/28/2006 82 Female 1/29/2008 Physician Italy
Primary
Concomitant
Renal Infarct Hospitalization 10/28/2007 61 Female 172 lb 2/12/2008 Physician Germany
Primary
Secondary
Concomitant
Flushing Hospitalization 12/1/2004 73 Female 2/21/2008 Germany
Primary
Secondary
Thrombocytopenia Hospitalization 11/14/2006 48 Male 201 lb 3/11/2008 Physician Germany
Primary
Secondary
Concomitant
Increased Tendency To Bruise Other Serious 6/28/2006 Female 3/19/2008 Physician Finland
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 79 Female 3/13/2008 Physician Canada
Primary
Concomitant
Vomiting Other Serious 70 Female 3/14/2008 Consumer
Primary
Concomitant
Muscular Weakness Life Threatening 2/28/2008 47 Female 111 lb 3/28/2008 Physician Germany
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 12/5/2007 74 Male 4/4/2008 Other Health Professional Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 4/7/2008 Physician Germany
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 12/5/2007 74 Male 4/8/2008 Other Health Professional Germany
Primary
Concomitant
Gastrointestinal Necrosis Hospitalization 12/13/2007 Male 202 lb 4/4/2008 Physician United States
Primary
Concomitant
Rash Other Serious 2/18/2008 73 Female 154 lb 4/8/2008 Physician Germany
Primary
Concomitant
Transaminases Increased Other Serious Male 194 lb 4/11/2008 Physician Germany
Primary
Concomitant
Paraesthesia Other Serious 2/1/2008 Male 198 lb 4/22/2008 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 4/10/2008 Female 174 lb 4/22/2008
Primary
Concomitant
Venous Insufficiency Hospitalization 4/11/2008 68 Male 148 lb 4/18/2008 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Death 4/11/2008 69 Male 139 lb 4/25/2008
Primary
Secondary
Dyspnoea Hospitalization 4/11/2008 68 Male 139 lb 4/30/2008 Other Health Professional Germany
Primary
Secondary
Dyspnoea Hospitalization 4/11/2008 68 Male 139 lb 5/6/2008 Physician Germany
Primary
Secondary
Red Blood Cell Count Decreased Hospitalization 4/11/2008 68 Male 148 lb 5/2/2008 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Death 4/11/2008 69 Male 139 lb 5/12/2008 Consumer Germany
Primary
Secondary
Palpitations Hospitalization 3/17/2008 76 Female 5/7/2008 Physician Germany
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 12/20/2007 68 Male 4/30/2008 Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/20/2007 68 Male 5/7/2008 Physician Germany
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 3/1/2008 Female 5/14/2008 Physician Germany
Primary
Concomitant
Dyspnoea Death 4/11/2008 68 Male 139 lb 5/13/2008 Pharmacist United States
Primary
Concomitant
Hepatorenal Syndrome Other Serious Male 194 lb 6/13/2008 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2008 Female 160 lb 6/19/2008 Canada
Primary
Concomitant
General Physical Health Deterioration Other Serious 67 Male 209 lb 6/17/2008 Physician Switzerland
Primary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 6/30/2008 Germany
Primary
Secondary
Concomitant
Helicobacter Infection Other Serious 67 Male 209 lb 6/27/2008 Physician Switzerland
Primary
Concomitant
Tremor Hospitalization 3/18/2008 Female 154 lb 7/2/2008 Physician Germany
Primary
Concomitant
Overdose Life Threatening 73 Male 231 lb 7/9/2008
Primary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 7/11/2008 Germany
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/11/2008 Male 7/14/2008 Physician Germany
Primary
Concomitant
Intestinal Perforation Hospitalization 12/13/2007 Male 202 lb 7/15/2008 Physician United States
Primary
Concomitant
Lactic Acidosis Other Serious 5/14/2008 75 Female 161 lb 7/18/2008 Consumer Germany
Primary
Concomitant
Hepatotoxicity Hospitalization 47 Male 7/18/2008 Spain
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Global Amnesia Other Serious 68 Female 8/13/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 8/18/2008 Germany
Primary
Secondary
Concomitant
Renal Cancer Life Threatening 2/1/2008 Female 203 lb 8/25/2008 Physician Germany
Primary
Concomitant
Flushing 6/1/2008 Male 223 lb 8/27/2008 United States
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 2/1/2008 Female 203 lb 9/3/2008 Physician Germany
Primary
Concomitant
Osteonecrosis Hospitalization 8/26/2008 Male 9/3/2008 Physician Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 7/1/2005 86 Female 9/8/2008 Consumer Netherlands
Primary
Concomitant
Osteonecrosis Hospitalization 8/26/2008 Male 9/8/2008 Physician Canada
Primary
Secondary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 9/5/2008 Germany
Primary
Secondary
Concomitant
Hepatorenal Syndrome Other Serious Male 194 lb 9/17/2008 Physician Germany
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 5/7/2008 Female 9/11/2008 Other Health Professional Portugal
Primary
Secondary
Concomitant
Urticaria Life Threatening 9/19/2008 Consumer Finland
Primary
Concomitant
Thrombocytopenia Other Serious 10/11/2008 Female 95 lb 10/20/2008 Bulgaria
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/11/2008 Female 95 lb 10/24/2008 Bulgaria
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/13/2008 Female 132 lb 10/29/2008 Physician Germany
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 2/1/2006 47 Male 10/30/2008
Primary
Secondary
Thrombocytopenia Other Serious 9/21/2008 Female 95 lb 11/3/2008 Bulgaria
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 1/1/2008 61 Female 146 lb 11/11/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 10/14/2008 67 Male 205 lb 11/13/2008 Consumer United States
Primary
Secondary
Concomitant
Muscle Abscess Hospitalization 7/7/2008 Male 231 lb 11/26/2008 Physician Germany
Primary
Concomitant
Metastases To Lymph Nodes Other Serious 10/29/2008 Female 11/26/2008 Other Health Professional Finland
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/10/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/15/2008 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 7/1/2008 51 Female 216 lb 12/17/2008 Pharmacist Germany
Primary
Concomitant
Wound Infection Hospitalization 10/28/2007 61 Female 176 lb 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/29/2008 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 54 Male 172 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Overdose Other Serious 10/15/2008 3/26/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 11/30/2008 Male 4/10/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/29/2009 65 Female 119 lb 4/6/2009 Germany
Primary
Concomitant
Somnolence Other Serious 2/3/2009 59 Male 4/21/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Somnolence Hospitalization 2/3/2009 59 Male 4/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Parathyroid Tumour Benign Other Serious 12/16/2008 53 Male 4/28/2009 Physician Germany
Primary
Secondary
Concomitant
Convulsion Other Serious 2/17/2009 Male 245 lb 5/1/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 3/24/2009 Male 165 lb 5/5/2009 Physician Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 4/21/2009 Female 5/6/2009 Physician Germany
Primary
Concomitant
Transaminases Increased Hospitalization 3/7/2009 64 Female 141 lb 5/12/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/16/2008 62 Male 236 lb 5/20/2009 Australia
Primary
Concomitant
Vomiting Hospitalization 3/7/2009 64 Female 5/22/2009 Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 10/28/2008 70 Male 183 lb 6/4/2009 Physician Israel
Primary
Concomitant
Road Traffic Accident Other Serious 1/1/2001 Male 180 lb 6/19/2009 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 11/2/2008 67 Male 7/6/2009 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Lung Infiltration Other Serious 5/22/2009 Male 7/6/2009 Physician Germany
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 73 Female 7/10/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Product Quality Issue 8/15/2007 56 Female 6/25/2009 Consumer United States
Primary
Concomitant
Vitritis Other Serious 7/19/2009 Female 8/10/2009 Physician Portugal
Primary
Concomitant
Sepsis Life Threatening 4/21/2009 64 Male 7/30/2009 Physician Germany
Primary
Concomitant
Vitritis Other Serious 7/19/2009 Female 8/20/2009 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 9/1/2009 78 Female 9/25/2009 Pharmacist Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 11/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 12/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Urosepsis Life Threatening 10/14/2009 Female 123 lb 1/14/2010 Physician Germany
Primary
Concomitant
Peripheral Vascular Disorder Other Serious 1/1/2006 Male 212 lb 1/15/2010 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 1/1/2009 Female 152 lb 1/25/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 12/18/2009 72 Male 2/18/2010 Physician Germany
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 1/1/2010 58 Male 381 lb 2/23/2010 Consumer Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 3/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Compartment Syndrome Life Threatening 2/9/2010 60 Male 254 lb 3/16/2010 Other Health Professional Germany
Primary
Concomitant
Waist Circumference Increased Other Serious 10/28/2009 79 Female 179 lb 3/20/2010 Other Health Professional Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Compartment Syndrome Life Threatening 2/9/2010 60 Male 254 lb 4/21/2010 Other Health Professional Germany
Primary
Concomitant
Syncope Hospitalization 5/26/2008 66 Male 234 lb 4/27/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/27/2010 Other Health Professional France
Primary
Secondary
Concomitant
Prothrombin Time Abnormal Hospitalization 1/1/2010 Female 5/3/2010 Physician Germany
Primary
Concomitant
Interacting
Diabetes Mellitus Other Serious 10/1/2009 63 Male 212 lb 5/3/2010 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 64 Female 141 lb 5/3/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 5/26/2008 66 Male 234 lb 5/4/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Prothrombin Time Prolonged Other Serious 8/16/2008 54 Male 172 lb 5/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2009 64 Female 141 lb 5/6/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/21/2009 64 Female 141 lb 5/6/2010 Physician Germany
Primary
Secondary
Concomitant

Drug Data