Bisoprolol Fumarate combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 9/4/2005 89 Male 170 lb 1/10/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Death 9/5/2005 33 Male 2/13/2006 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/16/2006 Physician Canada
Primary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/17/2006 Physician Canada
Primary
Concomitant
Gravitational Oedema Hospitalization 11/26/2005 80 Female 132 lb 3/9/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Overdose Hospitalization 1/23/2006 28 Female 3/2/2006 France
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 87 Male 2/28/2006 France
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 2/10/2006 64 Female 66 lb 4/26/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/24/2006 92 Female 88 lb 4/20/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Hospitalization 71 Male 5/19/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 2/1/2006 83 Female 112 lb 6/21/2006 United States
Primary
Concomitant
Tearfulness Hospitalization 3/8/2006 Female 6/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 2/23/2006 77 Female 6/23/2006 Physician United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 2/23/2006 77 Female 6/27/2006 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 3/8/2006 84 Female 99 lb 7/3/2006 France
Primary
Concomitant
Pyrexia Hospitalization 6/2/2006 76 Male 7/19/2006 Physician Italy
Primary
Concomitant
Viral Upper Respiratory Tract Infection Death 9/7/2005 73 Male 171 lb 7/21/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Somnolence Death 6/14/2006 89 8/2/2006 United Kingdom
Primary
Concomitant
Syncope Hospitalization 1/23/2006 58 Female 8/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/14/2006 89 Unknown 8/4/2006 United Kingdom
Primary
Concomitant
Cardiac Failure Acute Hospitalization 12/14/1998 73 Male 8/15/2006 France
Primary
Concomitant
Renal Failure Acute Other Serious 4/4/2006 91 Male 8/8/2006 Denmark
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2002 57 Male 8/8/2006 Other Health Professional Japan
Primary
Concomitant
Ischaemic Stroke Life Threatening 5/29/2006 86 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/1/2006 France
Primary
Concomitant
Blood Amylase Increased Other Serious 5/1/2005 78 Male 9/5/2006 United Kingdom
Primary
Concomitant
Somnolence Other Serious 7/2/2006 89 9/7/2006 Denmark
Primary
Concomitant
Platelet Count Decreased Disability 58 Male 9/12/2006 Physician United States
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/12/2006 France
Primary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/13/2006 Physician France
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 8/1/2005 65 Male 9/13/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2005 80 Female 9/29/2006 Consumer Canada
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Rash Hospitalization 1/1/2005 65 Female 10/17/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/5/2006 73 Male 165 lb 10/23/2006 Physician United Kingdom
Primary
Concomitant
Cardiogenic Shock Death 10/7/2006 59 Male 10/30/2006 Brazil
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2005 65 Female 180 lb 11/1/2006 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 8/2/2006 Male 12/5/2006 Physician France
Primary
Concomitant
Interacting
Benign Neoplasm Hospitalization 4/14/2005 92 Female 12/18/2006 Physician Japan
Primary
Concomitant
Pleural Effusion Death 9/29/2006 81 Female 143 lb 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Leukopenia Hospitalization 76 Female 12/21/2006 Poland
Primary
Concomitant
Vomiting Other Serious 9/1/2006 Female 1/5/2007 Physician Fiji
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/26/2006 36 Female 117 lb 1/11/2007 Physician Ireland
Primary
Concomitant
Vomiting Other Serious 9/1/2006 Female 1/17/2007 Physician Fiji
Primary
Secondary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 68 Male 172 lb 2/26/2007 Consumer United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 172 lb 2/26/2007 United Kingdom
Primary
Secondary
Vertigo Hospitalization 2/2/2007 69 Male 3/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Death 1/15/2007 80 Male 3/23/2007 France
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Death 1/15/2007 80 Male 4/3/2007 France
Primary
Secondary
Concomitant
Paraesthesia Other Serious 68 Male 4/4/2007 United Kingdom
Primary
Secondary
Pulmonary Fibrosis Hospitalization 2/1/2007 86 Female 4/18/2007 France
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 3/7/2007 77 Male 4/25/2007 Other Health Professional France
Primary
Secondary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 3/1/2006 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/7/2007 77 Male 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Diarrhoea Other Serious 4/18/2007 90 Female 154 lb 5/26/2007 United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 4/18/2007 90 Female 5/25/2007 United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 3/7/2007 Male 6/12/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/10/2007 79 Female 6/11/2007 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Pyrexia Other Serious 3/23/2007 72 Male 6/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/10/2007 79 Female 6/13/2007 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Renal Failure Hospitalization 5/10/2007 79 Female 6/13/2007 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/27/2006 73 Male 6/18/2007 Canada
Primary
Concomitant
Drug Interaction Hospitalization 5/16/2007 Female 6/28/2007 Other Health Professional France
Primary
Concomitant
Interacting
White Blood Cell Count Increased Hospitalization 71 Female 6/26/2007 Physician Belgium
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/3/2007 56 Male 7/6/2007 Other Health Professional Italy
Primary
Concomitant
Diarrhoea Other Serious 71 Female 7/9/2007 Belgium
Primary
Concomitant
Respiratory Failure Hospitalization 3/7/2007 Male 7/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/7/2007 77 Male 7/3/2007 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 7/4/2007 Male 137 lb 7/23/2007 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 12/1/2004 79 Female 8/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 8/3/2007 Finland
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/17/2007 75 Female 8/14/2007 Spain
Primary
Secondary
Concomitant
Necrosis Death 1/1/2007 71 Female 8/30/2007 Belgium
Primary
Secondary
Concomitant
Petit Mal Epilepsy Hospitalization 4/26/2007 73 Female 9/5/2007 Sweden
Primary
Secondary
Concomitant
Hepatitis Other Serious 6/20/2007 76 Male 9/19/2007 United Kingdom
Primary
Concomitant
Atrial Fibrillation Disability 6/27/2007 71 Male 9/20/2007 United Kingdom
Primary
Concomitant
Hepatitis Other Serious 6/20/2007 76 Male 9/13/2007 United Kingdom
Primary
Concomitant
Electrocardiogram Abnormal Hospitalization 4/26/2007 73 Female 9/11/2007 Sweden
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 58 Male 10/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Other Serious 6/20/2007 76 Male 10/1/2007 United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 10/3/2007 United Kingdom
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 Male 281 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 58 Male 10/15/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2007 85 Male 10/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 73 Male 10/22/2007 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 73 Male 10/19/2007 United Kingdom
Primary
Concomitant
Pain 1/1/2002 54 Male 10/24/2007 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 68 Male 10/26/2007 Other Health Professional France
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 5/10/2007 79 Female 10/25/2007 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Renal Failure Hospitalization 2/14/2007 Male 11/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 88 Female 11/8/2007 Other Health Professional France
Primary
Secondary
Concomitant
Scar Hospitalization 9/15/2007 Female 11/16/2007 Consumer Germany
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 74 Male 11/19/2007 United Kingdom
Primary
Concomitant
Tremor Other Serious 10/9/2007 Female 11/28/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Tremor Other Serious 10/9/2007 Female 12/7/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Wrist Fracture Hospitalization 88 Female 11/26/2007 France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/8/2007 61 Male 12/13/2007 Other Health Professional France
Primary
Concomitant
Nausea Hospitalization 11/11/2007 Female 1/17/2008 Other Health Professional Finland
Primary
Concomitant
Pancytopenia Hospitalization 10/19/2007 86 Female 1/18/2008
Primary
Secondary
Concomitant
Tendon Rupture Disability 12/25/2006 57 Male 1/16/2008 France
Primary
Secondary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 10/19/2007 86 Female 1/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/19/2007 86 Female 2/4/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 10/26/2007 70 Female 1/16/2008 France
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 10/26/2007 70 Female 2/6/2008 France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/7/2008 Male 163 lb 2/21/2008 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2007 79 Male 2/13/2008 Other Health Professional Israel
Primary
Concomitant
Pulmonary Cavitation Hospitalization 2/7/2008 66 Male 163 lb 2/25/2008 Consumer United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 77 Female 3/3/2008 Germany
Primary
Concomitant
Sepsis Hospitalization 1/28/2008 69 Female 3/12/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pulmonary Cavitation Hospitalization 2/7/2008 Male 163 lb 3/12/2008 Physician Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/28/2008 69 Female 3/13/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/11/2007 94 Female 99 lb 3/7/2008 Other Health Professional
Primary
Concomitant
Pulmonary Cavitation Hospitalization 2/7/2008 66 Male 163 lb 3/18/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/1/2007 79 Female 3/13/2008 Physician Canada
Primary
Concomitant
Renal Failure Hospitalization 3/2/2008 74 Male 4/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 1/20/2008 85 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 1/7/2008 83 Male 4/2/2008 Sweden
Primary
Concomitant
Rectal Cancer Other Serious 65 Female 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 11/6/2007 89 Female 4/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/7/2008 66 Male 163 lb 4/23/2008 Consumer United States
Primary
Secondary
Concomitant
Monocyte Percentage Increased Hospitalization 2/7/2008 Male 163 lb 4/28/2008 Physician Germany
Primary
Secondary
Concomitant
Drug Level Below Therapeutic Other Serious 1/1/2008 61 Male 4/25/2008 Physician United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization Female 4/30/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/1/2007 86 Male 5/6/2008 Pharmacist United States
Primary
Secondary
Muscle Spasms Hospitalization 4/18/2008 Male 158 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 1/25/2008 74 Male 5/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bile Duct Cancer Life Threatening 70 Female 143 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Bile Duct Cancer Life Threatening 70 Female 5/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 143 lb 5/16/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 68 Male 172 lb 6/2/2008 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Death 71 Female 5/29/2008 Belgium
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/2/2008 United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/2/2008 United Kingdom
Primary
Secondary
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 68 Male 5/30/2008 United Kingdom
Primary
Secondary
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 4/4/2008 88 Female 5/28/2008 Spain
Primary
Secondary
Concomitant

Drug Data