Bisoprolol Fumarate combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ischaemic Stroke Other Serious 8/1/2002 51 Female 115 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/31/2006 75 Female 5/16/2006 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 79 Female 7/14/2006 Physician France
Primary
Secondary
Concomitant
Diarrhoea 1/1/2005 77 Female 220 lb 8/1/2006 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 4/1/2003 Female 293 lb 8/9/2006 Consumer United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 7/3/2006 76 Male 10/3/2006 France
Primary
Concomitant
Fall Hospitalization 8/19/2006 75 Female 10/9/2006 Physician France
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 5/31/2003 79 Female 11/10/2006 France
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 9/28/2006 43 Male 205 lb 12/6/2006 Other Health Professional France
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 5/31/2003 79 Female 12/5/2006 France
Primary
Secondary
Concomitant
Skin Lesion Other Serious 11/7/2006 78 Male 1/11/2007 France
Primary
Secondary
Concomitant
Rash Other Serious 12/12/2006 62 Male 1/24/2007 Italy
Primary
Concomitant
Respiratory Arrest Life Threatening 2/18/2007 52 Female 3/15/2007 Other Health Professional France
Primary
Secondary
Concomitant
Swelling Other Serious 4/1/2007 Female 160 lb 6/11/2007 Consumer United States
Primary
Concomitant
Subdural Haematoma Other Serious 7/30/2007 74 Male 1/4/2008 Consumer France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/10/2007 Male 196 lb 1/16/2008 Physician Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 10/10/2007 Male 196 lb 1/16/2008 Physician Canada
Primary
Concomitant
Bronchostenosis Life Threatening 10/28/2007 80 Female 1/14/2008 Germany
Primary
Concomitant
Dyspnoea Life Threatening 10/28/2007 80 Female 1/30/2008 Italy
Primary
Concomitant
Urticaria Other Serious 10/29/2007 Female 205 lb 3/5/2008 Physician France
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 4/22/2008 Physician Canada
Primary
Concomitant
Pulmonary Congestion Hospitalization 1/1/2008 Female 5/1/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 5/13/2008 Physician Canada
Primary
Concomitant
Palpitations Other Serious 3/1/2008 Female 180 lb 6/4/2008 Physician Canada
Primary
Concomitant
Pharmaceutical Product Complaint 6/30/2008 57 Female 119 lb 7/24/2008 Pharmacist United States
Primary
Concomitant
Dyspnoea Life Threatening 10/28/2007 80 Female 9/9/2008 Italy
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/1/2008 Male 10/18/2008 Physician Italy
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/1/2008 Male 11/1/2008 Physician Italy
Primary
Concomitant
Presyncope Hospitalization 1/1/2008 Male 11/15/2008 Physician Italy
Primary
Concomitant
Vomiting Other Serious 12/9/2008 Female 12/26/2008 Other Health Professional Canada
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 10/21/2008 55 Male 1/16/2009 Pharmacist France
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 4/6/2007 68 Female 1/28/2009 France
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 11/3/2008 86 Female 2/17/2009 Physician France
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 11/3/2008 86 Female 2/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Death 71 Male 2/16/2009 France
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2008 79 Female 4/16/2009 Physician Canada
Primary
Concomitant
Transaminases Increased Hospitalization 3/30/2009 Male 5/5/2009 Other Health Professional France
Primary
Secondary
Concomitant
Presyncope Other Serious 1/1/2008 Male 5/18/2009 Physician Italy
Primary
Concomitant
Platelet Count Decreased Other Serious 3/9/2009 23 Male 148 lb 5/14/2009 Physician Italy
Primary
Concomitant
Rectal Haemorrhage Hospitalization Female 130 lb 7/16/2009 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2009 67 Male 216 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Generalised 70 Female 110 lb 7/22/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/23/2008 Male 9/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 8/1/2009 77 Female 10/29/2009 Pharmacist Italy
Primary
Secondary
Concomitant
Presyncope Other Serious 1/1/2008 Male 12/1/2009 Physician Italy
Primary
Concomitant
Vomiting Other Serious 10/28/2009 Female 1/13/2010 Canada
Primary
Concomitant
Rhinorrhoea 10/1/2009 Female 1/24/2010 Other Health Professional Canada
Primary
Concomitant
Fall Hospitalization 7/6/2007 Male 1/25/2010 Consumer Italy
Primary
Secondary
Concomitant
Urine Analysis Abnormal 5/1/2009 85 Male 1/13/2010 Physician United States
Primary
Concomitant
Respiratory Acidosis Other Serious 10/16/2009 86 Female 2/24/2010 France
Primary
Concomitant
Arrhythmia Hospitalization 4/1/2009 Male 194 lb 3/12/2010 Other Health Professional Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/23/2010 42 Female 3/31/2010 Italy
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 8/22/2009 87 Female 4/8/2010 Other Health Professional France
Primary
Concomitant
Subdural Haematoma Other Serious 3/25/2010 84 Male 123 lb 4/15/2010 Physician France
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization Female 130 lb 4/28/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization Female 130 lb 5/10/2010 Physician United States
Primary
Concomitant
Mouth Haemorrhage Other Serious 4/14/2010 77 Male 5/19/2010 Physician Italy
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 3/30/2009 38 Female 150 lb 5/20/2010 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/23/2010 42 Female 6/16/2010 Italy
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/17/2010 71 Female 7/9/2010 Physician Italy
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/17/2010 71 Female 7/19/2010 Physician Italy
Primary
Concomitant
Anaemia Hospitalization 3/14/2010 61 Male 7/29/2010 Other Health Professional
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 5/1/2010 62 Male 7/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/17/2010 71 Female 8/9/2010 Physician Italy
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/20/2010 89 Female 8/9/2010 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 8/12/2010 Physician Italy
Primary
Secondary
Concomitant
Flushing 5/1/2010 62 Male 250 lb 8/29/2010 Consumer United States
Primary
Concomitant
Staphylococcal Abscess Hospitalization 3/1/2009 73 Male 9/23/2010 Physician France
Primary
Concomitant
Staphylococcal Abscess Hospitalization 3/1/2009 73 Male 9/27/2010 Physician France
Primary
Concomitant
Overdose Hospitalization Female 10/27/2010 Consumer Italy
Primary
Concomitant
Serum Ferritin Increased Other Serious Female 128 lb 11/12/2010 Physician Canada
Primary
Concomitant
Urinary Retention Required Intervention 11/8/2008 81 Female 11/15/2010 Other Health Professional Germany
Primary
Concomitant
Cardiac Failure Other Serious 1/1/2010 85 Male 12/28/2010 Pharmacist Italy
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/10/2010 90 Male 1/10/2011 Consumer France
Primary
Secondary
Concomitant
Acute Respiratory Failure Other Serious 6/1/2008 65 Male 1/13/2011 Consumer Italy
Primary
Concomitant
Neutropenia Hospitalization 11/15/2010 68 Female 1/12/2011 Physician France
Primary
Secondary
Concomitant
Disturbance In Attention Hospitalization 12/1/2010 90 Male 1/14/2011 Physician France
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 6/1/2008 65 Male 2/2/2011 Consumer Italy
Primary
Concomitant
Drug Interaction Other Serious 5/19/2009 74 Male 2/4/2011 Other Health Professional France
Primary
Concomitant
Interacting
Oedema Peripheral Other Serious 11/20/2010 44 Female 2/7/2011 Consumer France
Primary
Secondary
Concomitant
Gingival Bleeding Hospitalization 5/19/2009 74 Male 2/4/2011 Other Health Professional France
Primary
Concomitant
Interacting
Psychomotor Skills Impaired Hospitalization 1/3/2011 81 Female 2/8/2011 Other Health Professional France
Primary
Concomitant
Gingival Bleeding Hospitalization 5/19/2009 74 Male 2/11/2011 Other Health Professional France
Primary
Concomitant
Interacting
Paranoia Hospitalization 1/1/2011 78 Female 2/28/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/12/2011 74 Male 205 lb 3/22/2011 Consumer France
Primary
Secondary
Concomitant
Asthenia Hospitalization 4/24/2011 85 Female 5/3/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Bacteraemia Hospitalization 4/1/2010 79 Male 5/13/2011 Physician France
Primary
Secondary
Concomitant
Extremity Necrosis Life Threatening 4/1/2010 79 Male 5/16/2011 Consumer France
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 5/3/2011 84 Female 5/26/2011 Physician France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/3/2011 84 Female 5/27/2011 Other Health Professional France
Primary
Concomitant
Interacting
Blood Creatinine Increased Other Serious Male 5/30/2011 Physician Canada
Primary
Concomitant
Chest Pain 4/19/2011 83 Female 6/1/2011 Consumer United States
Primary
Concomitant
Ischaemic Stroke Other Serious 6/1/2008 65 Male 6/1/2011 Physician Italy
Primary
Secondary
Stent Placement Other Serious 12/20/2010 79 Female 5/27/2011 Consumer Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/23/2011 80 Male 5/31/2011 Physician Germany
Primary
Concomitant
Dizziness Other Serious 91 Female 6/2/2011 Consumer Canada
Primary
Concomitant
Nausea Hospitalization 8/3/2010 84 Female 6/17/2011 Consumer Italy
Primary
Secondary
Concomitant
Haematoma Hospitalization 4/19/2009 78 Female 6/17/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Triglycerides Increased 5/27/2011 38 Male 230 lb 6/17/2011 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/13/2011 91 Female 6/27/2011 Consumer France
Primary
Concomitant
Myocardial Infarction Death 5/25/2011 73 Male 6/29/2011 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/8/2011 91 Female 7/5/2011 Consumer France
Primary
Concomitant
Sick Sinus Syndrome Other Serious 5/1/2011 71 Female 7/5/2011 Consumer Italy
Primary
Secondary
Concomitant
Confusional State Hospitalization 2/1/2011 74 Male 7/12/2011 Other Health Professional France
Primary
Concomitant
Somnolence Hospitalization 5/16/2011 91 Female 7/11/2011 Consumer France
Primary
Concomitant
Headache Other Serious 12/1/2009 85 Male 7/29/2011 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/1/2009 85 Male 8/3/2011 Physician France
Primary
Secondary
Concomitant
Duodenal Ulcer Other Serious 2/1/2011 77 Female 8/5/2011 Consumer France
Primary
Concomitant
Implant Site Infection Hospitalization 6/1/2011 57 Male 8/8/2011 Consumer France
Primary
Secondary
Concomitant
Dizziness Other Serious 5/24/2011 91 Female 104 lb 8/8/2011 Consumer Canada
Primary
Concomitant
Haematoma Hospitalization 6/30/2011 75 Female 168 lb 8/11/2011 Consumer France
Primary
Concomitant
Cardiac Failure Hospitalization 2/13/2011 90 Male 170 lb 8/16/2011 Physician Israel
Primary
Concomitant
Cardiac Failure Hospitalization 5/21/2011 91 Female 8/17/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 5/16/2011 91 Female 8/10/2011 Physician France
Primary
Concomitant
Haematoma Hospitalization 5/17/2011 89 Female 8/22/2011 Consumer France
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/18/2011 69 Male 187 lb 8/23/2011 Physician Israel
Primary
Concomitant
Hyperkalaemia Hospitalization 5/25/2011 91 Female 8/26/2011 Consumer France
Primary
Secondary
Concomitant
Overdose Hospitalization 3/14/2011 79 Female 8/12/2011 Other Health Professional France
Primary
Concomitant
Abnormal Behaviour Hospitalization 5/21/2011 91 Female 9/1/2011 Other Health Professional France
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 7/1/2011 76 Male 9/6/2011 Physician France
Primary
Secondary
Concomitant
Haematoma Hospitalization 6/14/2011 72 Male 9/7/2011 Physician France
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/30/2011 84 Male 198 lb 9/7/2011 Other Health Professional France
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 7/12/2011 77 Female 9/12/2011 Other Health Professional France
Primary
Concomitant
Arthropathy Hospitalization 1/1/2007 79 Female 9/9/2011 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 7/1/2011 64 Male 9/16/2011 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 4/3/2011 75 Female 9/15/2011 Other Health Professional Italy
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/3/2011 86 Male 9/26/2011 Consumer France
Primary
Concomitant
Interacting
Cardiac Failure Hospitalization 2/13/2011 90 Male 170 lb 9/27/2011 Physician Israel
Primary
Concomitant
Blood Pressure Increased Hospitalization 8/30/2011 81 Female 10/7/2011 Physician France
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/11/2011 87 Female 11/16/2011 Other Health Professional Italy
Primary
Concomitant
Splenic Rupture Life Threatening 1/1/2011 81 Male 11/23/2011 Consumer France
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 10/11/2011 87 Female 11/28/2011 Other Health Professional Italy
Primary
Concomitant
Cardiac Failure Hospitalization 9/1/2011 88 Male 11/29/2011 Physician France
Primary
Secondary
Concomitant
Cough Hospitalization 8/17/2011 78 Male 11/29/2011 Physician Italy
Primary
Secondary
Concomitant
Dementia Alzheimer's Type Hospitalization 6/18/2011 84 Female 11/23/2011 Other Health Professional France
Primary
Concomitant
Hearing Impaired Other Serious 7/1/2010 85 Female 12/2/2011 Consumer United States
Primary
Concomitant
Cardiomegaly Hospitalization 4/1/2011 12/6/2011 Other Health Professional France
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/31/2011 74 Male 216 lb 12/9/2011 Physician Canada
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2011 84 Male 12/12/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Hypercapnia Life Threatening 6/16/2008 71 Male 230 lb 12/5/2011 Lawyer United States
Primary
Concomitant
Bradycardia Hospitalization 10/17/2011 79 Male 12/9/2011 Italy
Primary
Secondary
Concomitant
Muscle Haemorrhage Hospitalization 2/3/2011 87 Male 12/15/2011 Consumer Italy
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 6/18/2011 84 Female 12/13/2011 Other Health Professional France
Primary
Concomitant
Loss Of Consciousness Other Serious 8/2/2008 77 Male 12/20/2011 Physician Canada
Primary
Concomitant
Muscle Haemorrhage Hospitalization 2/3/2011 87 Male 12/22/2011 Other Health Professional Italy
Primary
Concomitant
Syncope Hospitalization 8/14/2011 84 Male 12/22/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2011 84 Male 12/23/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Anaemia Hospitalization 1/9/2010 82 Female 1/9/2012 Physician France
Primary
Concomitant
Muscle Haemorrhage Hospitalization 2/3/2011 87 Male 1/9/2012 Consumer Italy
Primary
Concomitant
Arthritis Other Serious 1/1/2007 79 Female 1/10/2012 Consumer United States
Primary
Concomitant

Drug Data