Bisoprolol Fumarate combined with Bumetanide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Shock Life Threatening 67 Female 1/9/2006 United Kingdom
Primary
Secondary
Sinoatrial Block Other Serious 67 Female 2/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Shock Hospitalization 67 Female 2/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Shock Life Threatening 67 Female 2/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization Female 2/16/2006 Ireland
Primary
Secondary
Concomitant
Sinoatrial Block Hospitalization 67 Female 3/14/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/17/2006 65 Male 4/11/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 4/7/2005 73 Male 4/18/2006 Other Health Professional France
Primary
Concomitant
Ventricular Arrhythmia Death 4/7/2005 73 Male 190 lb 4/27/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Other Serious 4/26/2006 82 Female 162 lb 6/7/2006 Physician United Kingdom
Primary
Concomitant
Blood Amylase Increased Other Serious 5/1/2005 78 Male 9/5/2006 United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Abscess Hospitalization 8/22/2005 53 Male 10/27/2006 Physician France
Primary
Secondary
Concomitant
Shock Hospitalization 67 Female 1/23/2007 Consumer United Kingdom
Primary
Secondary
Rash Pruritic Hospitalization 3/24/2007 75 Male 4/25/2007 United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 4/26/2007 United Kingdom
Primary
Concomitant
Pruritus Hospitalization 4/1/2006 84 Male 5/3/2007 Other Health Professional France
Primary
Secondary
Pain Disability 2/14/2007 Male 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cells Urine Positive Other Serious 7/17/2006 Male 5/18/2007 Physician Belgium
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 5/31/2007 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 67 Female 7/27/2007 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 67 Female 9/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Unresponsive To Stimuli Life Threatening 67 Female 9/11/2007 United Kingdom
Primary
Secondary
Unresponsive To Stimuli Other Serious 67 Female 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Shock Life Threatening 67 Female 9/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Unresponsive To Stimuli Life Threatening 67 Female 8/24/2007 United Kingdom
Primary
Secondary
Septic Shock Death 10/3/2007 Female 134 lb 10/10/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/12/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 Female 134 lb 10/15/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death 10/3/2007 73 Female 10/19/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 1/1/2003 67 Female 10/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Perforation Death 10/3/2007 Female 134 lb 10/29/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Small Intestinal Perforation Death 10/3/2007 Female 134 lb 11/2/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Sinoatrial Block Life Threatening 1/1/2003 67 Female 10/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 1/21/2008 Consumer United Kingdom
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polymyositis Hospitalization 12/1/2006 77 Male 2/18/2008 Other Health Professional Norway
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 3/4/2008 Consumer United Kingdom
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 11/26/2007 67 Male 234 lb 3/7/2008 Physician United Kingdom
Primary
Concomitant
Jaundice Hospitalization 2/28/2008 76 Male 265 lb 3/19/2008 Consumer United Kingdom
Primary
Concomitant
Pericardial Effusion Other Serious 3/16/2007 79 Male 3/26/2008 United States
Primary
Concomitant
Syncope Life Threatening 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 11/10/2007 Male 5/23/2008 Other Health Professional France
Primary
Secondary
Syncope Life Threatening 83 Female 143 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 143 lb 5/16/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 83 Female 5/30/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 6/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Syncope Other Serious 83 Female 6/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 83 Female 143 lb 6/10/2008
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious Female 6/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Gallbladder Cancer Life Threatening 4/30/2008 Male 192 lb 6/27/2008 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 84 Female 7/29/2008 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 84 Female 9/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Other Serious 10/1/2008 Female 154 lb 12/29/2008 Consumer Ireland
Primary
Concomitant
Thrombocytopenia Death 1/3/2009 73 Male 3/5/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Pyrexia Death 71 Male 2/16/2009 France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2009 73 Male 3/13/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 6/8/2009 Female 7/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 9/1/2008 78 Female 130 lb 10/2/2009 Physician Belgium
Primary
Concomitant
Condition Aggravated Hospitalization 9/7/2009 75 Female 243 lb 10/12/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Parotitis Other Serious 11/21/2009 75 Female 1/13/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 86 Male 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2009 63 Male 5/4/2010 Physician Ireland
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 10/19/2009 86 Male 6/9/2010 United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 5/16/2010 81 Female 110 lb 6/11/2010 Physician Belgium
Primary
Concomitant
Renal Failure Hospitalization 62 Male 7/2/2010 Physician United Kingdom
Primary
Concomitant
Systemic Sclerosis Other Serious 5/23/2010 64 Male 7/20/2010 Belgium
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 2/8/2010 63 Male 9/7/2010 Physician Ireland
Primary
Concomitant
Purpura Hospitalization 9/9/2010 74 Male 11/2/2010 Physician France
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 9/9/2010 74 Male 1/11/2011 Physician France
Primary
Secondary
Concomitant
Drug Clearance Decreased Death 1/27/2011 77 Male 252 lb 2/3/2011 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 3/2/2011 Physician Netherlands
Primary
Concomitant
Pancytopenia Hospitalization 1/1/2011 82 Male 172 lb 3/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 2/22/2006 76 Female 150 lb 4/12/2011 Pharmacist Netherlands
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2011 82 Male 172 lb 5/4/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 3/16/2011 72 Female 5/6/2011 Other Health Professional France
Primary
Secondary
Nausea Hospitalization 5/3/2011 75 Female 170 lb 5/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 80 Male 6/22/2011 Other Health Professional
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 9/8/2010 61 Male 172 lb 7/8/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Life Threatening 9/8/2010 61 Male 172 lb 7/11/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Hospitalization 9/8/2010 61 Male 172 lb 7/12/2011 Physician United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 80 Male 6/28/2011 Other Health Professional Belgium
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 80 Male 7/5/2011 Other Health Professional
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 7/4/2011 83 Female 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cholestasis Hospitalization 7/4/2011 83 Female 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cholestasis Hospitalization 7/4/2011 83 Female 7/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Death Death 3/4/2011 79 Male 141 lb 8/4/2011 Physician Belgium
Primary
Concomitant
Bradycardia Life Threatening 7/14/2011 65 Female 209 lb 8/9/2011 Pharmacist United Kingdom
Primary
Concomitant
Arteriosclerosis Coronary Artery Death 6/2/2009 80 Male 8/11/2011 Consumer United Kingdom
Primary
Concomitant
Myositis Hospitalization 7/4/2011 83 Female 8/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bradycardia Life Threatening 7/14/2011 65 Male 212 lb 8/16/2011 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/22/2011 35 Male 8/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Myositis Hospitalization 7/4/2011 83 Female 8/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Hospitalization 7/4/2011 83 Female 8/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 7/22/2011 35 Male 8/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 7/22/2011 35 Male 8/25/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/22/2011 35 Male 8/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Impaired Healing Life Threatening Male 136 lb 8/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 7/22/2011 35 Male 8/19/2011 Other Health Professional
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/22/2011 35 Male 8/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 7/22/2011 35 Male 8/23/2011 Other Health Professional
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 7/22/2011 35 Male 8/23/2011 Other Health Professional
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 7/22/2011 35 Male 8/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 8/16/2011 76 Female 181 lb 9/2/2011 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 11/27/2009 85 Female 170 lb 9/6/2011 Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 80 Male 9/16/2011 Belgium
Primary
Concomitant
Interacting
Nephrotic Syndrome Hospitalization 8/16/2011 76 Female 181 lb 9/19/2011 Physician United Kingdom
Primary
Concomitant
Acidosis Hospitalization 10/19/2009 86 Male 9/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/11/2011 66 Female 10/10/2011 Physician Norway
Primary
Concomitant
Atrial Fibrillation Other Serious 1/14/2010 88 Female 11/1/2011 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/1/2011 68 Male 11/4/2011 Physician Norway
Primary
Concomitant
Sudden Cardiac Death Hospitalization 9/17/2011 75 Male 179 lb 11/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 9/29/2009 60 Male 172 lb 12/9/2011 Physician United Kingdom
Primary
Concomitant
Rash Vesicular Disability 9/19/2011 83 Male 12/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 7/22/2011 35 Male 1/25/2012 Other Health Professional
Primary
Secondary
Concomitant
Tongue Oedema Other Serious 72 Male 1/31/2012 Physician Sweden
Primary
Concomitant
Renal Failure Acute Hospitalization 6/6/2011 77 Female 1/31/2012 Other Health Professional France
Primary
Secondary
Concomitant
Death Death Female 2/9/2012 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Death 12/25/2011 77 Female 2/17/2012 Physician Belgium
Primary
Concomitant
Death Death Female 2/27/2012 Other Health Professional United Kingdom
Primary
Concomitant
Generalised Oedema Hospitalization 12/26/2011 76 Male 2/29/2012 Physician Belgium
Primary
Concomitant
Dehydration Other Serious 12/25/2011 77 Female 3/2/2012 Physician Belgium
Primary
Concomitant
Urinary Retention Hospitalization 2/19/2012 63 Male 258 lb 3/5/2012 United Kingdom
Primary
Concomitant
Melaena Hospitalization 1/2/2012 81 Female 3/5/2012 Physician Belgium
Primary
Concomitant
Dehydration Other Serious 12/25/2011 77 Female 3/6/2012 Physician Belgium
Primary
Concomitant
Cardiac Failure Death 12/25/2011 77 Female 3/12/2012 Physician Belgium
Primary
Concomitant
Nausea Hospitalization 5/25/2011 62 Female 3/14/2012 Physician United Kingdom
Primary
Concomitant
Cardiovascular Disorder Death 4/1/2011 61 Male 3/23/2012 Consumer Belgium
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 83 Male 3/28/2012 Other Health Professional Belgium
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 3/1/2012 69 Male 3/30/2012 Other Health Professional United Kingdom
Primary
Concomitant
Blood Creatine Increased Other Serious 1/1/2011 77 Female 132 lb 4/3/2012 Physician Belgium
Primary
Concomitant
Renal Failure Acute Hospitalization 12/30/2011 63 Male 258 lb 4/3/2012 Physician United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 12/30/2011 63 Male 258 lb 4/19/2012 United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 63 Male 4/17/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 12/18/2011 60 Male 208 lb 4/24/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Confusional State Other Serious 12/30/2011 63 Male 258 lb 4/25/2012 United Kingdom
Primary
Concomitant
Syncope Other Serious 4/10/2012 69 Male 183 lb 4/25/2012 Physician France
Primary
Secondary
Concomitant
Syncope Other Serious 4/10/2012 69 Male 183 lb 4/30/2012 Physician France
Primary
Secondary
Concomitant

Drug Data