Bisoprolol combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Death 12/1/2005 60 Male 187 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Hepatotoxicity Hospitalization 1/30/2006 71 Female 3/10/2006 Pharmacist United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Death 2/9/2006 76 Female 3/15/2006 Physician Hungary
Primary
Secondary
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/7/2005 73 Male 4/13/2006 Physician Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 4/27/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/1/2006
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/19/2006 83 Female 112 lb 5/23/2006 Consumer United States
Primary
Concomitant
Shock Other Serious 68 172 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 3/7/2007 Physician United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 Unknown 172 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 3/9/2007 Other Health Professional France
Primary
Secondary
Paraesthesia Other Serious 68 Male 3/7/2007 United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 Male 4/3/2007 Consumer United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 Male 4/3/2007 Consumer United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 Male 4/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 4/11/2007 Other Health Professional France
Primary
Secondary
Paraesthesia Other Serious 68 172 lb 6/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Overdose Disability 80 Female 6/29/2007 Physician United Kingdom
Primary
Concomitant
Shock Other Serious 68 172 lb 6/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Death Death 7/4/2007 Male 137 lb 8/13/2007 Physician United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 8/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Disability 6/27/2007 71 Male 8/29/2007 United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/14/2007 79 Male 9/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Atrial Fibrillation Disability 6/27/2007 71 Male 9/11/2007 United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 9/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 9/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 6/14/2007 Male 9/20/2007 Other Health Professional France
Primary
Concomitant
Interacting
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bone Marrow Disorder Other Serious 11/24/2006 Male 216 lb 12/18/2007 United Kingdom
Primary
Concomitant
Bone Marrow Disorder Other Serious 11/24/2006 Male 216 lb 12/19/2007 Physician United Kingdom
Primary
Concomitant
Subdural Haematoma Life Threatening 8/15/2007 75 Female 12/20/2007 Other Health Professional France
Primary
Secondary
Renal Failure Hospitalization 2/14/2007 Male 12/20/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2004 76 Male 12/31/2007 Finland
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious 4/26/2006 Female 117 lb 12/28/2007 Physician Ireland
Primary
Concomitant
Visual Acuity Reduced Disability 10/30/2007 75 Female 1/2/2008 Consumer France
Primary
Concomitant
Renal Failure Other Serious 3/15/2006 Male 216 lb 1/10/2008 Physician United Kingdom
Primary
Concomitant
Radius Fracture Hospitalization 12/10/2007 Female 135 lb 1/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/11/2007 94 Female 99 lb 2/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 79 Female 2/1/2008 Physician Canada
Primary
Concomitant
Syncope Hospitalization 1/20/2008 85 Male 165 lb 2/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 73 Male 212 lb 5/9/2008 Physician United Kingdom
Primary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 7/26/2008 70 Male 8/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Shock Other Serious 68 172 lb 9/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Shock Other Serious 68 172 lb 10/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Propofol Infusion Syndrome Other Serious 67 Male 168 lb 1/15/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 1/25/2008 74 Male 1/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 1/23/2009 Consumer Canada
Primary
Concomitant
Pruritus Hospitalization 12/1/2008 Male 181 lb 1/26/2009 Other Health Professional Finland
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 1/27/2009 Consumer Switzerland
Primary
Concomitant
Pruritus Hospitalization 7/28/2008 75 Female 144 lb 1/29/2009 Physician United Kingdom
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 2/5/2009 Physician Canada
Primary
Concomitant
Death Other Serious 12/15/2008 79 Female 2/3/2009 Physician Canada
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 2/18/2009 Physician Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 7/26/2008 70 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Hospitalization 7/28/2008 75 Female 144 lb 3/4/2009 Physician United Kingdom
Primary
Concomitant
Pruritus Hospitalization 7/28/2008 75 Female 144 lb 3/6/2009 Physician United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/1/2008 74 Male 3/6/2009 Physician Switzerland
Primary
Concomitant
Interacting
Cardiac Failure Other Serious 48 Male 3/9/2009 Physician United States
Primary
Concomitant
Pallor Death 12/15/2008 79 Female 3/6/2009 Physician Canada
Primary
Concomitant
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 4/1/2009 Consumer United Kingdom
Primary
Secondary
Pneumonia Other Serious 1/1/2008 79 Female 4/2/2009 Physician Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 4/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Vertigo Hospitalization 2/22/2008 4/20/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Gout Other Serious 3/21/2009 4/28/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 68 Male 4/27/2009
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Myocardial Infarction Hospitalization 2/1/2009 Female 122 lb 5/12/2009 United States
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 67 Male 5/12/2009 United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 5/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 5/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Infection Other Serious 5/1/2007 Male 179 lb 5/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 67 Male 6/3/2009 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2008 79 Female 6/12/2009 Physician Canada
Primary
Concomitant
Angina Pectoris Other Serious 4/25/2009 Male 271 lb 6/18/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 67 Male 6/17/2009 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/26/2008 70 Male 6/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 3/3/2009 Male 6/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 Male 172 lb 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Rectal Cancer Other Serious 3/1/2008 Male 203 lb 7/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 68 Male 7/2/2009 Consumer United Kingdom
Primary
Secondary
Haemorrhage Urinary Tract Hospitalization 4/10/2009 Female 176 lb 7/6/2009 Physician Denmark
Primary
Concomitant
Interacting
Syncope Hospitalization 79 Female 7/6/2009 Consumer United Kingdom
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/1/2009 67 Male 7/1/2009 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 7/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Syncope Hospitalization 79 Female 7/10/2009 Denmark
Primary
Concomitant
Gout Other Serious 3/21/2009 73 7/21/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 7/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Paraesthesia Other Serious 68 Male 7/24/2009 Other Health Professional France
Primary
Secondary
Weight Decreased Other Serious 4/21/2008 66 Male 179 lb 7/21/2009 United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 68 Male 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Required Intervention 68 Male 7/29/2009
Primary
Secondary
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Sepsis Other Serious 12/29/2008 Female 8/6/2009 Physician Canada
Primary
Concomitant
Pancreatitis Life Threatening 6/9/2009 68 Male 229 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/5/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/10/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/13/2009 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 9/2/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/6/2009 9/21/2009 Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 10/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Sciatica Other Serious 9/1/2009 Female 10/9/2009 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious Male 10/19/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 10/17/2009 United States
Primary
Concomitant
Surgery Hospitalization 72 Female 10/20/2009 Lawyer United States
Primary
Concomitant
Sepsis Other Serious 12/29/2008 Female 10/28/2009 Physician Canada
Primary
Concomitant
Subdural Haematoma Hospitalization 9/29/2009 87 Male 10/28/2009 Other Health Professional Germany
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Vascular Calcification Hospitalization 71 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Wrong Drug Administered Death Female 11/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Snoring Hospitalization 71 Male 11/4/2009 United States
Primary
Concomitant
Wrong Drug Administered Death Female 11/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/4/2009 Consumer United States
Primary
Concomitant
Wrong Drug Administered Death 89 Female 11/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 Male 11/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neuralgia Life Threatening 10/9/2009 88 Male 11/24/2009 United Kingdom
Primary
Concomitant
Torsade De Pointes Life Threatening 4/30/2009 75 Female 11/25/2009 Physician Spain
Primary
Concomitant
Interacting
Vascular Calcification Hospitalization 71 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 Male 12/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/24/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2006 Female 117 lb 11/30/2009 Physician Ireland
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 5/10/2007 79 Female 11/30/2009 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Aspergillosis Hospitalization 2/7/2008 Male 163 lb 11/30/2009 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2008 79 Female 12/1/2009 Physician Canada
Primary
Concomitant
Medication Error Death Female 12/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Medication Error Death Female 12/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 12/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 12/10/2009 Consumer United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 12/10/2009 Consumer United Kingdom
Primary
Secondary

Drug Data