Bisoprolol combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/7/2006 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/27/2006 Other Health Professional Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/8/2002 56 Female 154 lb 5/3/2006 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/31/2004 75 Male 180 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Life Threatening 5/15/2007 71 Female 7/6/2007 Physician Italy
Primary
Secondary
Concomitant
Stomatitis Life Threatening 5/15/2007 71 Female 7/10/2007 Physician Italy
Primary
Secondary
Concomitant
Palpitations Hospitalization 7/18/2007 80 Female 140 lb 8/28/2007 Physician Canada
Primary
Concomitant
Urticaria Disability 62 Female 9/7/2007 Consumer United States
Primary
Concomitant
Pain 5/1/2007 79 Male 180 lb 12/17/2007 United States
Primary
Concomitant
Diarrhoea Hospitalization 8/1/2007 Male 1/31/2008 Physician Canada
Primary
Concomitant
Fungal Oesophagitis Hospitalization 9/23/2008 Female 243 lb 10/10/2008 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Other Serious 12/23/2008 Male 1/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 1/23/2009 Consumer Canada
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 2/5/2009 Physician Canada
Primary
Concomitant
Retinal Artery Occlusion Required Intervention 1/29/2009 Female 190 lb 2/8/2009 Pharmacist United States
Primary
Concomitant
Death Other Serious 12/15/2008 79 Female 2/3/2009 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 12/23/2008 Male 2/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 2/18/2009 Physician Canada
Primary
Concomitant
Pallor Death 12/15/2008 79 Female 3/6/2009 Physician Canada
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 79 Female 4/2/2009 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 12/23/2008 Male 5/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 5/11/2009 88 Female 6/15/2009 Physician France
Primary
Concomitant
Interacting
Pneumonia Other Serious 1/1/2008 79 Female 6/12/2009 Physician Canada
Primary
Concomitant
Pleural Effusion Hospitalization 4/1/2009 80 Female 6/26/2009 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization Female 130 lb 7/2/2009 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2009 67 Male 216 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Generalised 70 Female 110 lb 7/22/2009 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization Female 130 lb 8/4/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/31/2004 75 Male 180 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/17/2009 Other Health Professional Canada
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/31/2004 75 Male 180 lb 8/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 8/25/2009 Male 9/16/2009 Consumer Italy
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 10/19/2009 United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 6/1/2009 Male 10/29/2009 Consumer Italy
Primary
Secondary
Concomitant
Snoring Hospitalization 71 Male 11/4/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/4/2009 Consumer United States
Primary
Concomitant
Vascular Calcification Hospitalization 71 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/24/2009 Lawyer United States
Primary
Concomitant
Pulmonary Congestion Hospitalization 1/1/2008 Female 12/1/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 79 Female 12/1/2009 Physician Canada
Primary
Concomitant
Palpitations Hospitalization 12/28/2009 70 Male 1/27/2010 Consumer Canada
Primary
Concomitant
Visual Impairment Other Serious 9/1/2006 Female 2/10/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/1/2009 82 Male 2/12/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 10/28/2009 Female 3/3/2010 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 12/26/2009 61 Female 260 lb 3/8/2010 Consumer United States
Primary
Concomitant
Pain Disability 3/7/2010 69 Female 3/23/2010 Consumer Canada
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 3/16/2010 Male 143 lb 3/26/2010 Other Health Professional Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 3/31/2010 United States
Primary
Concomitant
Nausea 1/25/2010 4/12/2010 Other Health Professional Canada
Primary
Concomitant
Diarrhoea 2/1/2010 62 Female 4/12/2010 Physician Canada
Primary
Secondary
Concomitant
Haemoglobin Decreased 12/22/2009 62 Female 4/12/2010 Other Health Professional Canada
Primary
Concomitant
Syncope Other Serious 8/2/2008 77 Male 4/15/2010 Physician Canada
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 76 Female 4/26/2010 Physician Canada
Primary
Secondary
Concomitant
Wheezing Hospitalization 56 Female 200 lb 4/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 10/1/2009 55 Female 174 lb 5/13/2010 Consumer United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 10/12/2009 76 Female 5/18/2010 Physician Canada
Primary
Secondary
Concomitant
Vertigo Hospitalization 69 Male 5/11/2010 Lawyer United States
Primary
Concomitant
Anaemia Hospitalization 3/14/2010 61 Male 6/7/2010 Other Health Professional
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/10/2010 64 Female 6/11/2010 Physician Italy
Primary
Concomitant
Interacting
Ventricular Tachycardia Other Serious 37 Male 6/7/2010 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/22/2010 79 Female 6/22/2010 Physician Italy
Primary
Secondary
Concomitant
Mouth Haemorrhage Other Serious 4/14/2010 77 Male 6/25/2010 Physician Italy
Primary
Secondary
Concomitant
Mouth Haemorrhage Other Serious 4/14/2010 77 Male 7/6/2010 Physician Italy
Primary
Secondary
Concomitant
Mouth Haemorrhage Other Serious 4/14/2010 77 Male 7/6/2010 Physician Italy
Primary
Secondary
Concomitant
Mouth Haemorrhage Other Serious 4/14/2010 77 Male 7/6/2010 Physician Italy
Primary
Secondary
Concomitant
Haematoma Hospitalization 3/27/2010 74 Male 7/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Haematoma Hospitalization 5/27/2010 74 Male 7/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 76 Female 7/26/2010 United States
Primary
Concomitant
Cardiac Fibrillation Hospitalization Female 9/17/2010 Physician Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/31/2010 88 Male 9/20/2010 Physician Italy
Primary
Interacting
Rash Pustular Hospitalization 8/30/2010 70 Female 10/5/2010 Physician Italy
Primary
Secondary
Serum Ferritin Increased Other Serious Female 128 lb 10/4/2010 Physician Canada
Primary
Concomitant
Serum Ferritin Increased Other Serious Female 128 lb 10/5/2010 Physician Canada
Primary
Concomitant
Diabetes Mellitus Other Serious 10/1/2009 55 Female 124 lb 10/6/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Death 10/18/2010 Pharmacist Italy
Primary
Concomitant
Vertigo Hospitalization 6/28/2010 84 Female 11/10/2010 Pharmacist United States
Primary
Concomitant
Vulvovaginal Pruritus Other Serious Female 12/23/2010 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 75 Male 227 lb 12/24/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/27/2010 72 Female 1/6/2011 Other Health Professional Israel
Primary
Concomitant
Off Label Use Other Serious 46 Male 1/13/2011 Physician Israel
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 12/20/2010 79 Female 1/17/2011 Consumer Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/27/2010 72 Female 1/19/2011 Other Health Professional Israel
Primary
Concomitant
Diarrhoea Haemorrhagic Hospitalization 10/18/2010 83 Female 1/21/2011 Consumer France
Primary
Concomitant
Haematochezia 1/6/2011 69 Male 1/21/2011 Consumer
Primary
Concomitant
Blood Potassium Increased Hospitalization 10/1/2010 83 Female 148 lb 1/28/2011 Physician France
Primary
Concomitant
Interacting
Headache Hospitalization 1/1/2011 78 Female 2/17/2011 Consumer United States
Primary
Concomitant
Erythema Multiforme Hospitalization 3/4/2011 75 Male 201 lb 3/18/2011 Physician Canada
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/5/2011 96 Female 3/28/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 2/5/2011 96 Female 3/31/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Erythema Multiforme Hospitalization 3/4/2011 75 Male 201 lb 4/26/2011 Physician Canada
Primary
Secondary
Concomitant
Atrioventricular Block First Degree Hospitalization 6/16/2011 92 Female 6/30/2011 Consumer Italy
Primary
Concomitant
Renal Failure Hospitalization 6/14/2011 72 Male 7/18/2011 Physician France
Primary
Concomitant
Diarrhoea Hospitalization 10/8/2010 59 Female 10/7/2011 Consumer United States
Primary
Concomitant
Drug Administration Error Hospitalization 1/1/2011 70 Female 10/9/2011 Physician Italy
Primary
Concomitant
Oropharyngeal Discomfort 83 Male 10/24/2011 Consumer United States
Primary
Concomitant
Compression Fracture Hospitalization 1/1/2007 79 Female 10/28/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Administration Error Hospitalization 1/1/2011 70 Female 10/31/2011 Consumer Italy
Primary
Concomitant
Rhabdomyolysis Death 10/11/2011 87 Female 11/1/2011 Physician Italy
Primary
Concomitant
Haemorrhage Death 8/29/2011 74 Male 216 lb 12/23/2011 Physician Canada
Primary
Secondary
Concomitant
Tachycardia Hospitalization 11/1/2008 54 Female 1/3/2012 Consumer Canada
Primary
Concomitant
Confusional State Hospitalization 75 Male 1/3/2012 Physician Israel
Primary
Concomitant
Orthostatic Hypotension Hospitalization 10/20/2011 95 Female 1/20/2012 Other Health Professional France
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 10/20/2011 95 Female 1/20/2012 France
Primary
Secondary
Concomitant
Diarrhoea Other Serious 7/1/2010 85 Female 2/10/2012 Physician United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/5/2012 76 Male 5/1/2012 Physician Italy
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/5/2012 76 Male 5/14/2012 Physician Italy
Primary
Concomitant
Renal Failure Acute Hospitalization 4/2/2010 77 Male 176 lb 9/7/2012 Physician It
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 7/18/2011 49 Male 209 lb 10/10/2012 Physician De
Primary
Secondary
Concomitant
Colitis Ischaemic Other Serious 5/9/2012 72 Male 144 lb 11/26/2012 Physician Ca
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/4/2012 61 Male 8/30/2012 Other Health Professional It
Primary
Concomitant
Interacting
Ischaemic Stroke Hospitalization Female 217 lb 6/14/2013 Consumer Ca
Primary
Concomitant
Renal Failure Acute Other Serious 4/2012 81 Male 10/8/2012 Consumer Fr
Primary
Concomitant
Interacting
Vomiting Other Serious 7/2012 69 Male 190 lb 1/25/2013 Physician Fr
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 2011 71 Female 10/26/2012 Consumer Ca
Primary
Concomitant
Tachycardia Other Serious 11/17/2012 85 Female 12/11/2012 Physician It
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/11/2012 74 Female 1/9/2013 Other Health Professional It
Primary
Concomitant
Interacting
Presyncope Hospitalization 10/18/2012 82 Female 1/23/2013 Other Health Professional It
Primary
Concomitant
Renal Haematoma Hospitalization 12/29/2012 68 NotSpecified 254 lb 2/14/2013 Other Health Professional It
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 12/21/2012 73 Male 1/30/2013 Other Health Professional It
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 11/6/2012 66 Male 4/3/2013 Consumer De
Primary
Concomitant
Hypertensive Crisis Hospitalization 1/12/2013 76 Male 1/30/2013 Other Health Professional It
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/5/2012 63 Male 309 lb 2/22/2013 Pharmacist Gb
Primary
Concomitant
International Normalised Ratio Increased Other Serious 12/30/2012 76 Female 2/1/2013 Physician Dk
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/16/2013 64 Male 3/12/2013 Other Health Professional It
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 12/21/2012 73 Male 1/31/2013 Pharmacist Dk
Primary
Secondary
Concomitant
Skin Ulcer Haemorrhage Hospitalization 2/27/2013 Female 3/20/2013 Other Health Professional It
Primary
Concomitant
Interacting
Asthenia Hospitalization 1/22/2013 37 Male 7/1/2013 Other Health Professional It
Primary
Secondary
Concomitant
Lung Infection Hospitalization 3/27/2013 61 Male 190 lb 6/11/2013 Physician Ca
Primary
Concomitant
Renal Failure Acute Other Serious 5/27/2013 66 Male 6/11/2013 Other Health Professional It
Primary
Secondary
Concomitant
Rash Hospitalization 5/13/2013 73 Male 6/19/2013 Physician It
Primary
Concomitant
Right Ventricular Failure Death 6/2013 86 Female 123 lb 7/31/2013 Physician Ca
Primary
Concomitant
Varicose Vein 8/27/2012 71 Male 185 lb 8/2/2013 Physician Us
Primary
Secondary
Concomitant
Swelling Other Serious 1/26/2012 63 Female 285 lb 8/22/2013 Consumer Ca
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 8/16/2013 49 Male 185 lb 9/12/2013 Physician De
Primary
Concomitant
Skin Plaque Disability 63 Female 160 lb 9/25/2013 Consumer Ca
Primary
Concomitant
Syncope Other Serious 7/4/2013 75 Male 10/2/2013 Pharmacist It
Primary
Secondary
Concomitant
Oliguria Hospitalization 2/17/2013 80 Female 10/3/2013 Physician It
Primary
Secondary
Concomitant
Urticaria Other Serious 9/13/2013 87 Female 10/31/2013 Physician It
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 10/28/2013 70 Male 11/20/2013 Consumer Co
Primary
Secondary
Concomitant
Sopor Hospitalization 4/17/2013 86 Female 12/13/2013 Other Health Professional It
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/22/2011 62 Male 7/18/2013 Physician Il
Primary
Concomitant

Drug Data