Bisoprolol combined with Bumetanide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Walking Disability Other Serious 12/1/2005 Female 1/31/2006 Physician Netherlands
Primary
Concomitant
Walking Disability Other Serious 12/1/2005 Female 2/2/2006 Physician Netherlands
Primary
Concomitant
Renal Failure Acute Hospitalization 67 Female 2/9/2006 Consumer United Kingdom
Primary
Secondary
Walking Disability Other Serious 12/1/2005 Female 2/14/2006 Physician Netherlands
Primary
Concomitant
Ventricular Failure Required Intervention 12/1/2005 Female 2/8/2006 Physician Netherlands
Primary
Concomitant
Shock Hospitalization 67 Female 3/10/2006 Consumer United Kingdom
Primary
Secondary
Shock Hospitalization 67 Female 3/12/2007 Consumer United Kingdom
Primary
Secondary
Hyperkalaemia Hospitalization 3/28/2007 75 Male 4/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 67 Female 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tinnitus Other Serious 8/1/2007 Male 1/21/2009 Consumer United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 1/27/2009 Consumer Switzerland
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2009 79 Female 146 lb 4/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sensory Disturbance Other Serious 11/17/2008 80 Male 4/17/2009 Physician
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 66 Female 5/6/2009 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/25/2009 66 Female 5/12/2009 United Kingdom
Primary
Concomitant
Palpitations Hospitalization 5/26/2009 69 6/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 6/22/2009 70 8/3/2009 Australia
Primary
Concomitant
Troponin Increased Other Serious 10/1/2008 Female 154 lb 10/12/2009 Consumer Ireland
Primary
Concomitant
Swollen Tongue Other Serious 9/13/2009 81 Female 234 lb 10/21/2009 Other Health Professional Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2009 79 Female 146 lb 2/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/15/2010 4/23/2010 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 2/1/2010 63 Male 5/14/2010 Physician Ireland
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 5/18/2010 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 5/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 6/3/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 6/11/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Hospitalization 62 Male 6/17/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 8/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatic Neoplasm Other Serious 7/21/2010 66 Male 9/15/2010 Physician United Kingdom
Primary
Concomitant
Haematemesis Death 10/17/2010 61 Male 10/21/2010 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 68 Female 214 lb 10/28/2010 Physician United Kingdom
Primary
Concomitant
Therapeutic Response Decreased 5/1/2009 12/19/2010 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 12/29/2010 Physician Netherlands
Primary
Concomitant
Cardiac Arrest Hospitalization 9/8/2010 61 Male 172 lb 1/12/2011 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 1/1/2011 82 Male 172 lb 1/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/8/2010 61 Male 172 lb 1/31/2011 Physician United Kingdom
Primary
Concomitant
Renal Failure Chronic Life Threatening 9/8/2010 61 Male 172 lb 2/4/2011 Physician United Kingdom
Primary
Concomitant
Hyperthyroidism Hospitalization 1/20/2011 75 Male 2/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Life Threatening 9/8/2010 61 Male 172 lb 2/14/2011 Physician United Kingdom
Primary
Concomitant
Gastric Cancer Death Male 2/14/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 2/15/2011 Physician Netherlands
Primary
Concomitant
Off Label Use Other Serious 73 Female 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Other Serious 73 Female 6/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Death Death 3/4/2011 79 Male 141 lb 7/15/2011 Physician Belgium
Primary
Concomitant
Atrial Fibrillation Hospitalization 9/8/2010 61 Male 172 lb 7/22/2011 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/22/2011 35 Male 8/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Cardiac Death Hospitalization 9/17/2011 75 Male 179 lb 10/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bundle Branch Block Right Death Male 11/1/2011 Netherlands
Primary
Concomitant
Hypoglycaemia Hospitalization 7/22/2011 35 Male 1/24/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Female 1/26/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Female 1/30/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/4/2012 88 Female 1/31/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Hospitalization 9/17/2011 75 Male 179 lb 2/2/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 1/1/2012 73 Female 135 lb 2/3/2012 Consumer United States
Primary
Concomitant
Urosepsis Hospitalization 1/4/2012 88 Female 2/7/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Female 2/7/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2012 84 Female 6/22/2012 Physician Belgium
Primary
Concomitant
Atrial Fibrillation Hospitalization 9/28/2011 Male 185 lb 6/22/2012 Physician Belgium
Primary
Concomitant
Blister Death 6/2/2012 79 Female 122 lb 8/13/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 6/12/2012 76 Female 8/13/2012 Pharmacist United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/2/2012 79 Female 122 lb 8/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 1/1/2012 82 Female 131 lb 8/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Disability 64 Female 219 lb 8/14/2012 Consumer United Kingdom
Primary
Concomitant
Ulcer Hospitalization 82 Female 131 lb 8/15/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Death 6/2/2012 79 Female 122 lb 8/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 6/2/2012 79 Female 122 lb 8/17/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pain Death 6/2/2012 79 Female 122 lb 8/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 67 Female 1/15/2013 Physician Gb
Primary
Concomitant
Syncope Other Serious 4/10/2012 69 Male 183 lb 4/19/2013 Physician Fr
Primary
Secondary
Concomitant
Rectal Adenocarcinoma Death 1/5/2012 88 Male 148 lb 5/2/2013 Other Health Professional Be
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/4/2012 83 Male 4/22/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/17/2012 83 Female 10/1/2012 Other Health Professional Il
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/21/2012 71 Female 126 lb 6/8/2013 Physician Be
Primary
Concomitant
Vasculitis Other Serious 5/8/2012 79 Female 122 lb 10/17/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 8/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 10/24/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/2/2012 79 Female 122 lb 6/20/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Atrial Fibrillation Disability 64 Female 219 lb 10/5/2013 Consumer Gb
Primary
Concomitant
Oedema Other Serious 7/17/2012 51 Male 9/2/2012 Other Health Professional Gb
Primary
Concomitant
Terminal State Death 50 Female 11/26/2012 Physician Gb
Primary
Concomitant
Purpura Other Serious 71 Female 9/20/2012 Other Health Professional Nl
Primary
Concomitant
Interacting
Vasculitis Other Serious Female 9/20/2012 Other Health Professional Nl
Primary
Concomitant
Interacting
Chapped Lips Hospitalization 8/15/2012 50 9/25/2012 Other Health Professional Gb
Primary
Concomitant
Chapped Lips Other Serious 8/15/2012 50 9/27/2012 Other Health Professional Gb
Primary
Concomitant
Chapped Lips Hospitalization 8/15/2012 50 10/2/2012 Pharmacist Gb
Primary
Concomitant
Chapped Lips Hospitalization 8/15/2012 50 10/4/2012 Other Health Professional Gb
Primary
Concomitant
Lip Pain Hospitalization 8/15/2012 50 10/2/2012 Gb
Primary
Concomitant
Lip Pain Hospitalization 8/15/2012 50 10/2/2012 Gb
Primary
Concomitant
Pneumonia Other Serious Female 192 lb 5/7/2013 Physician Gb
Primary
Concomitant
Metastatic Neoplasm Hospitalization 10/1/2012 82 Male 2/7/2013 Physician Gb
Primary
Concomitant
Pneumonia Other Serious 12/15/2011 54 Male 219 lb 11/2/2012 Other Health Professional Gb
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/2/2012 79 Female 11/8/2012 Pharmacist Gb
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/30/2012 69 Male 173 lb 11/24/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Intracardiac Thrombus Other Serious 10/15/2012 69 Male 236 lb 10/2/2013 Other Health Professional Gb
Primary
Concomitant
Peripheral Ischaemia Hospitalization 11/16/2012 81 Female 143 lb 4/21/2013 Physician Ie
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 82 Male 1/12/2013 Other Health Professional Nl
Primary
Concomitant
Hyperthyroidism Other Serious 72 Male 2/15/2013 Country Not Specified
Primary
Concomitant
Hypoglycaemia Other Serious 12/2012 84 Male 1/31/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Acute Hospitalization 12/5/2012 63 Male 309 lb 2/22/2013 Pharmacist Gb
Primary
Concomitant
Incorrect Dose Administered Death 1/5/2013 64 Female 309 lb 1/22/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 5/2/2012 67 Male 6/7/2013 Physician Gb
Primary
Concomitant
Viral Infection Hospitalization 3/17/2013 70 Female 103 lb 7/17/2013 Physician Be
Primary
Concomitant
Sinus Arrest Hospitalization 4/6/2013 82 Female 4/24/2013 Physician Be
Primary
Concomitant
Syncope Death 3/20/2013 93 Male 150 lb 5/1/2013 Physician Gb
Primary
Concomitant
Hypoaesthesia Other Serious 3/24/2013 75 NotSpecified 11/14/2013 Physician Gb
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/2013 67 Male 165 lb 4/21/2013 Pharmacist Gb
Primary
Concomitant
Syncope Hospitalization 75 Male 4/21/2013 Physician Gb
Primary
Concomitant
Oedema Hospitalization 4/11/2013 92 Female 4/26/2013 Other Health Professional Nl
Primary
Concomitant
Tremor Other Serious 2/26/2013 56 Male 231 lb 5/20/2013 Pharmacist Gb
Primary
Concomitant
Pain In Extremity Other Serious 4/19/2013 81 Male 5/24/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Acute Hospitalization 3/22/2013 82 Male 143 lb 6/25/2013 Pharmacist Nl
Primary
Concomitant
Nausea Hospitalization 6/17/2013 81 Female 167 lb 7/15/2013 Physician Gb
Primary
Concomitant
Renal Impairment Other Serious 2/19/2013 79 Male 231 lb 9/10/2013 Physician Gb
Primary
Concomitant
Melaena Hospitalization 7/13/2013 81 Male 187 lb 7/31/2013 Physician Gb
Primary
Concomitant
Tricuspid Valve Incompetence Death 7/15/2013 87 Female 119 lb 12/6/2013 Other Health Professional Gb
Primary
Concomitant
Melaena Life Threatening 7/13/2013 81 Male 187 lb 8/11/2013 Physician Gb
Primary
Concomitant
Melaena Hospitalization 7/13/2013 81 Male 187 lb 8/12/2013 Other Health Professional Gb
Primary
Concomitant
Stevens-johnson Syndrome Death 76 Male 8/15/2013 Other Health Professional Gb
Primary
Concomitant
Atrial Fibrillation Other Serious 8/2/2013 66 Male 258 lb 12/20/2013 Other Health Professional Gb
Primary
Concomitant
Melaena Hospitalization 79 Female 142 lb 8/21/2013 Pharmacist Gb
Primary
Concomitant
Vomiting Hospitalization 4/23/2013 66 Male 397 lb 11/19/2013 Other Health Professional Gb
Primary
Concomitant
Vomiting Hospitalization 4/23/2013 66 Male 397 lb 11/25/2013 Physician Gb
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/5/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/10/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Interacting
Weight Bearing Difficulty Life Threatening 8/17/2013 73 Male 9/6/2013 Consumer Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/13/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Rheumatic Disorder Other Serious 9/12/2013 79 Male 209 lb 10/21/2013 Pharmacist Fr
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 8/17/2013 73 Male 9/16/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Disability 8/17/2013 73 Male 9/17/2013 Consumer Gb
Primary
Secondary
Concomitant
Weight Bearing Difficulty Life Threatening 8/17/2013 73 Male 9/18/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 9/24/2013 86 Female 12/18/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Acute Hospitalization 9/27/2013 82 Male 148 lb 10/30/2013 Pharmacist Gb
Primary
Concomitant
Renal Failure Acute Hospitalization 9/27/2013 82 Male 148 lb 10/25/2013 Other Health Professional Gb
Primary
Concomitant

Drug Data