Biotin combined with Folic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Multiple Fractures Hospitalization 2/2/2004 64 Female 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Thinking Abnormal 6/1/2005 55 Female 230 lb 1/5/2006 Consumer United States
Primary
Concomitant
Pruritus 1/13/2006 49 Female 3/12/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2003 65 Female 126 lb 5/18/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 3/17/2003 78 Female 135 lb 5/11/2006 United States
Primary
Concomitant
Therapy Non-responder Other Serious 3/17/2003 78 Female 135 lb 5/25/2006 United States
Primary
Concomitant
Pruritus 1/13/2006 49 Female 6/6/2006 United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2006 80 Female 130 lb 9/8/2006 United States
Primary
Secondary
Concomitant
Myalgia Other Serious 4/18/2006 76 Male 194 lb 11/29/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2006 Female 130 lb 1/11/2007 Physician United States
Primary
Secondary
Concomitant
Pubic Rami Fracture Other Serious 8/1/2006 66 Male 206 lb 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocythaemia Other Serious 10/30/2006 88 Female 110 lb 6/11/2007 Other Health Professional Portugal
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 6/25/2007 United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 7/6/2007 United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 1/4/2008 United States
Primary
Concomitant
Scrotal Swelling Hospitalization 1/13/2008 Male 172 lb 2/25/2008 Greece
Primary
Concomitant
Feeling Jittery 1/1/2007 60 Male 1/10/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 1/1/2008 85 Female 2/29/2008 United States
Primary
Concomitant
Accidental Exposure 1/25/2008 Female 153 lb 3/15/2008 Consumer United States
Primary
Concomitant
Injection Site Urticaria 1/31/2008 Female 124 lb 3/15/2008 United States
Primary
Concomitant
Renal Failure Life Threatening 2/1/2008 41 Female 4/15/2008 Physician United States
Primary
Concomitant
Scrotal Swelling Hospitalization 1/13/2008 Male 172 lb 5/22/2008 Greece
Primary
Concomitant
Renal Failure Life Threatening 2/1/2008 41 Female 5/23/2008 Physician United States
Primary
Concomitant
Renal Failure Life Threatening 2/1/2008 41 Female 5/29/2008 Physician United States
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 7/9/2008 United States
Primary
Concomitant
Urinary Tract Infection 3/1/2008 70 Female 7/7/2008 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 37 Female 8/7/2008 United Kingdom
Primary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 9/11/2008 United States
Primary
Concomitant
Viral Infection Hospitalization 1/1/2006 70 Male 195 lb 10/3/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/27/2007 Female 150 lb 10/23/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased 1/1/2006 69 Female 135 lb 10/9/2008 United States
Primary
Concomitant
Peritonitis Other Serious 1/8/2008 Female 177 lb 12/5/2008 Japan
Primary
Concomitant
Tremor 4/10/2008 Female 12/9/2008 Physician United States
Primary
Concomitant
Osteolysis Hospitalization 2/9/2007 Male 160 lb 12/26/2008 United States
Primary
Concomitant
Dehydration Hospitalization 12/31/2008 53 Male 170 lb 1/9/2009 Physician Singapore
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/31/2008 53 Male 170 lb 1/19/2009 Physician Singapore
Primary
Secondary
Concomitant
Rash Vesicular 11/1/2008 73 Male 2/17/2009 Consumer
Primary
Concomitant
Pleural Effusion Other Serious Male 187 lb 3/17/2009 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 9/1/2007 69 Female 170 lb 4/13/2009 United States
Primary
Concomitant
Pleural Effusion Other Serious Male 187 lb 4/23/2009 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 69 Female 170 lb 4/23/2009 United States
Primary
Concomitant
Ill-defined Disorder Other Serious 3/4/2009 41 Female 5/12/2009 Physician United Kingdom
Primary
Secondary
Surgery Hospitalization 1/1/2002 Female 5/14/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 3/1/2005 61 Male 246 lb 5/15/2009 United States
Primary
Concomitant
Chest Pain Hospitalization 68 Male 6/4/2009 Physician United States
Primary
Concomitant
Rash 10/1/2008 Female 130 lb 6/12/2009 Consumer United States
Primary
Concomitant
Renal Cancer Metastatic Death 7/23/2008 61 Female 105 lb 7/22/2009 Physician United States
Primary
Concomitant
Rash Vesicular 11/1/2008 73 Male 8/24/2009 Consumer
Primary
Concomitant
Pruritus 6/1/2009 Female 145 lb 8/22/2009 United States
Primary
Concomitant
Death Death 7/15/2009 Female 155 lb 8/28/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/25/2008 Female 153 lb 9/12/2009 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 54 Female 168 lb 9/23/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 7/15/2009 Female 154 lb 11/2/2009 Consumer United States
Primary
Concomitant
Panic Reaction Other Serious 1/1/1969 24 Male 165 lb 11/3/2009 Consumer United States
Primary
Secondary
Concomitant
Blood Magnesium Decreased Female 135 lb 11/24/2009 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/27/2007 Female 150 lb 12/1/2009 Physician United States
Primary
Concomitant
Somnolence Life Threatening 11/26/2009 57 Female 170 lb 12/16/2009 Consumer United States
Primary
Concomitant
Pubis Fracture Other Serious 8/1/2006 Male 206 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Swelling 8/1/2009 Female 140 lb 1/29/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/14/2009 Female 220 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant
Gallbladder Perforation Hospitalization 9/21/2009 Female 172 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 10/14/2009 Female 220 lb 3/10/2010 Other Health Professional United States
Primary
Concomitant
Dermatitis Acneiform Hospitalization 10/13/2009 Female 3/26/2010 Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/14/2009 Female 220 lb 3/29/2010 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 9/21/2009 Female 172 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 10/14/2009 38 Female 4/7/2010 Japan
Primary
Concomitant
Bone Disorder Other Serious 1/1/2006 61 Female 129 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Dermatitis Acneiform Hospitalization 10/14/2009 38 Female 4/22/2010 Japan
Primary
Concomitant
Vomiting Other Serious 11/1/2008 55 Female 208 lb 5/6/2010 United States
Primary
Concomitant
Bone Disorder Other Serious 1/1/2006 61 Female 129 lb 5/18/2010 Other Health Professional United States
Primary
Concomitant
Metrorrhagia 2/5/2007 39 Female 155 lb 7/9/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 62 Female 125 lb 8/2/2010 Consumer United States
Primary
Concomitant
Pruritus 6/1/2010 80 Female 137 lb 8/9/2010 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2008 44 Female 201 lb 8/18/2010 Lawyer United States
Primary
Concomitant
Pruritus Female 172 lb 8/28/2010 United States
Primary
Concomitant
Pain Hospitalization 7/15/2010 Female 9/2/2010 Consumer
Primary
Concomitant
Thrombosis Hospitalization 1/1/2007 77 Male 9/3/2010 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 85 Male 9/8/2010 Consumer United States
Primary
Concomitant
Nausea 10/1/2009 Female 9/14/2010 Consumer United States
Primary
Concomitant
Dermatitis Acneiform Hospitalization 10/13/2009 38 Female 9/28/2010 Physician Japan
Primary
Concomitant
Skin Discolouration Hospitalization 12/1/2007 44 Female 201 lb 9/30/2010 Lawyer United States
Primary
Concomitant
Skin Discolouration Hospitalization 12/1/2007 44 Female 201 lb 9/30/2010 Lawyer United States
Primary
Concomitant
Oropharyngeal Pain Hospitalization 10/13/2009 38 Female 10/26/2010 Physician Japan
Primary
Concomitant
Mental Impairment Other Serious 11/12/2010 58 Male 198 lb 11/18/2010 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 10/1/2010 39 Female 443 lb 12/7/2010 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 85 Male 12/9/2010 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 85 Male 12/15/2010 Physician United States
Primary
Concomitant
Injection Site Swelling 2/15/2010 12/19/2010 Consumer United States
Primary
Concomitant
Injection Site Warmth 7/1/2010 12/23/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2010 57 Male 198 lb 12/28/2010 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 10/1/2010 39 Female 443 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Cataract Other Serious 85 Male 1/21/2011 Physician United States
Primary
Concomitant
Pain In Extremity 53 Female 1/29/2011 Consumer United States
Primary
Concomitant
Mobility Decreased 6/30/2010 68 Female 226 lb 1/29/2011 Other Health Professional United States
Primary
Concomitant
Candidiasis 9/20/2010 58 Female 1/30/2011 Consumer United States
Primary
Concomitant
Nasopharyngitis 12/4/2010 57 Female 1/30/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/1/2010 63 Female 164 lb 1/30/2011 Pharmacist United States
Primary
Concomitant
Ear Neoplasm Malignant Other Serious 9/27/2010 39 Female 443 lb 2/4/2011 Physician United States
Primary
Secondary
Concomitant
Hostility Other Serious 11/12/2010 58 Male 198 lb 2/9/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 11/12/2010 58 Male 198 lb 2/11/2011 Consumer United States
Primary
Concomitant
Overdose 62 Female 2/21/2011 Consumer United States
Primary
Concomitant
Skin Graft Other Serious 9/27/2010 39 Female 443 lb 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Limb Injury Other Serious 12/16/2010 62 Female 200 lb 3/15/2011 Consumer United States
Primary
Concomitant
Suicidal Ideation Hospitalization 3/20/2011 42 Female 196 lb 4/4/2011 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 4/1/2011 60 Female 5/6/2011 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 4/19/2011 69 Female 128 lb 6/7/2011 Physician United States
Primary
Concomitant
Dizziness Other Serious 1/1/2009 64 Male 227 lb 6/15/2011 Consumer Canada
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 77 Female 88 lb United States
Primary
Concomitant
Limb Injury Other Serious 12/16/2010 62 Female 200 lb 6/23/2011 Physician United States
Primary
Concomitant
Muscle Atrophy Hospitalization 1/1/2009 64 Male 227 lb 6/30/2011 Consumer Canada
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/19/2011 69 Female 128 lb 7/18/2011 Physician United States
Primary
Concomitant
Sensation Of Foreign Body 7/1/2011 76 Female 7/18/2011 Consumer United States
Primary
Concomitant
Tenderness Other Serious 1/1/2009 64 Male 227 lb 7/26/2011 Consumer Canada
Primary
Secondary
Concomitant
Nasal Congestion 1/1/2011 50 Female 7/27/2011 Consumer United States
Primary
Concomitant
Middle Insomnia Female 165 lb 8/6/2011 Consumer United States
Primary
Concomitant
Cough Female 167 lb 8/29/2011 Consumer United States
Primary
Concomitant
Fatigue 1/1/2011 50 Female 9/1/2011 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 10/1/2010 69 Female 200 lb 10/19/2011 Physician United States
Primary
Concomitant
Headache Hospitalization 9/25/2011 36 Female 145 lb 10/24/2011 Consumer Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2010 61 Female 156 lb 10/28/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2010 61 Female 156 lb 10/28/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 9/1/2010 54 Female 225 lb 10/28/2011 Physician United States
Primary
Concomitant
Mental Disorder 11/25/2010 53 Female 135 lb 10/28/2011 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pruritus 6/1/2011 54 Female 177 lb 11/2/2011 Consumer United States
Primary
Concomitant
Chest Pain 12/1/2010 65 Female 149 lb 12/19/2011 Consumer United States
Primary
Secondary
Concomitant
Sinusitis 11/1/2011 63 Female 1/11/2012 Consumer United States
Primary
Concomitant
Sinusitis 11/1/2011 63 Female 1/11/2012 Consumer United States
Primary
Concomitant
Cholecystitis Chronic Hospitalization 6/11/2010 29 Female 135 lb 1/12/2012 Consumer United States
Primary
Secondary
Concomitant
Back Pain 1/1/2011 71 Female 1/24/2012 Consumer United States
Primary
Concomitant
Pruritus 12/1/2010 76 Female 134 lb 1/26/2012 Physician United States
Primary
Concomitant
Injection Site Haematoma 1/22/2012 69 Female 130 lb 1/26/2012 Consumer United States
Primary
Concomitant
Constipation 12/1/2010 58 Male 1/27/2012 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased 12/1/2010 60 Female 1/28/2012 Consumer United States
Primary
Concomitant
Headache 1/18/2011 49 Female 1/27/2012 Consumer United States
Primary
Concomitant
Blister 6/1/2010 56 Female 212 lb 1/27/2012 Consumer United States
Primary
Concomitant
Skin Mass Other Serious 2/1/2011 76 Female 180 lb 1/27/2012 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 1/24/2011 61 Female 159 lb 1/27/2012 Consumer United States
Primary
Concomitant
Weight Increased Female 292 lb 1/28/2012 Physician United States
Primary
Concomitant
Alopecia 1/1/2009 48 Female 238 lb 1/28/2012 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haematoma 7/1/2011 59 Female 205 lb 1/28/2012 Consumer United States
Primary
Concomitant
Sinus Disorder 1/1/2011 75 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 12/27/2011 46 Female 1/29/2012 Consumer United States
Primary
Concomitant
Diarrhoea 11/7/2011 63 Female 1/29/2012 Consumer United States
Primary
Concomitant
Cough 11/22/2011 59 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Thrombosis 9/7/2011 67 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage Other Serious 11/1/2011 57 Female 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 69 Female 2/7/2012 Consumer United States
Primary
Concomitant
Paraesthesia 12/12/2011 52 Female 292 lb 2/17/2012 Consumer United States
Primary
Concomitant
Body Height Decreased Other Serious 12/1/2011 69 Female 180 lb 2/23/2012 Consumer United States
Primary
Concomitant
Impaired Healing Other Serious 11/1/2011 57 Female 124 lb 3/2/2012 Physician United States
Primary
Secondary
Concomitant

Drug Data