Biofermin combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Injury Asphyxiation Other Serious 12/1/2005 80 Female 106 lb 2/10/2006 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/20/2005 41 Female 99 lb 2/13/2006 Physician Japan
Primary
Secondary
Urinary Retention Other Serious 2/4/2005 79 Female 106 lb 2/18/2006 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/20/2005 41 Female 99 lb 2/22/2006 Physician Japan
Primary
Secondary
Hallucination Hospitalization 8/17/2005 69 Female 97 lb 3/3/2006 Physician Japan
Primary
Concomitant
Injury Asphyxiation Death 12/1/2005 80 Female 106 lb 3/18/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/1/2005 Female 3/21/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/4/2005 79 Female 106 lb 3/23/2006 Physician Japan
Primary
Concomitant
Hallucination Hospitalization 8/17/2005 69 Female 97 lb 3/28/2006 Physician Japan
Primary
Concomitant
Visual Disturbance Disability 5/23/2005 78 Female 4/3/2006 Physician Japan
Primary
Concomitant
Purpura Hospitalization 6/1/2005 Female 4/21/2006 Physician Japan
Primary
Concomitant
Purpura Life Threatening 6/1/2005 Female 5/24/2006 Physician Japan
Primary
Concomitant
Renal Failure Disability 12/27/2005 Male 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 3/28/2006 68 Male 126 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/27/2005 Male 6/15/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/4/2005 79 Female 106 lb 6/19/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 12/27/2005 Male 119 lb 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 6/2/2006 85 Male 7/11/2006 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/28/2006 64 Male 139 lb 9/21/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 10/1/2005 92 Female 10/6/2006 Pharmacist Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/3/2006 64 Male 139 lb 11/16/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 10/1/2005 92 Female 11/20/2006 Pharmacist Japan
Primary
Concomitant
Purpura Life Threatening 6/22/2005 Female 128 lb 5/3/2007 Japan
Primary
Concomitant
Vomiting Other Serious 5/10/2007 57 Female 8/9/2007 Physician Japan
Primary
Secondary
Vomiting Other Serious 5/10/2007 57 Female 8/16/2007 Physician Japan
Primary
Secondary
Torsade De Pointes Life Threatening 6/16/2007 Male 132 lb 8/31/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 9/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 6/16/2007 Male 132 lb 9/10/2007 Physician Japan
Primary
Secondary
Concomitant
Toothache Other Serious 7/4/2006 44 Female 11/1/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 6/16/2007 Male 132 lb 11/19/2007 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/6/2006 74 Female 128 lb 11/26/2007 Physician Japan
Primary
Concomitant
Toothache Other Serious 7/4/2006 44 Female 12/6/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/6/2006 74 Female 128 lb 12/12/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 12/27/2005 77 Male 119 lb 3/20/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 2/1/2008 72 Female 4/4/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 3/31/2008 65 Male 128 lb 9/2/2008 Other Health Professional Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 9/21/2008 82 Male 10/7/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 3/31/2008 65 Male 128 lb 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Malaise Hospitalization 4/7/2008 76 Female 86 lb 12/23/2008 Physician Japan
Primary
Concomitant
Lymph Node Tuberculosis Hospitalization 8/1/2008 Female 121 lb 12/31/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/16/2009 Male 168 lb 2/2/2009 Physician Japan
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Hospitalization 8/1/2008 Female 121 lb 2/3/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/15/2009 Male 168 lb 3/12/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 1/3/2009 Male 3/18/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/7/2008 Male 3/20/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 3/9/2009 82 Female 84 lb 4/7/2009 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 1/15/2009 Male 168 lb 4/13/2009 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Hospitalization 4/21/2009 65 Male 6/30/2009 Pharmacist Japan
Primary
Concomitant
Respiratory Failure Other Serious 6/24/2008 Male 7/4/2009 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 8/14/2008 Female 99 lb 7/10/2009 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 4/21/2009 65 Male 7/22/2009 Pharmacist Japan
Primary
Concomitant
Septic Shock Life Threatening 8/14/2008 Female 99 lb 8/10/2009 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 8/14/2008 Female 99 lb 9/7/2009 Physician Japan
Primary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 10/16/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2008 Female 11/9/2009 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/1/2008 Female 11/9/2009 Other Health Professional Japan
Primary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 12/14/2009 Physician Japan
Primary
Concomitant
Multi-organ Failure Other Serious 12/26/2009 Female 116 lb 2/5/2010
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 12/26/2009 Female 116 lb 2/10/2010
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 12/26/2009 Female 116 lb 2/23/2010
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 12/26/2009 Female 116 lb 2/24/2010
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 12/26/2009 Female 116 lb 3/4/2010
Primary
Secondary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 10/1/2009 90 Male 110 lb 3/15/2010 Pharmacist Japan
Primary
Concomitant
Interacting
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 10/20/2009 80 Male 110 lb 3/22/2010 Pharmacist Japan
Primary
Concomitant
Interacting
Multi-organ Failure Other Serious 12/26/2009 49 Female 116 lb 4/12/2010
Primary
Secondary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 4/26/2010 Physician Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 11/9/2008 71 Male 126 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 12/26/2009 49 Female 116 lb 5/17/2010
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 5/1/2010 58 Male 5/17/2010 Japan
Primary
Concomitant
Multi-organ Failure Other Serious 12/26/2009 49 Female 116 lb 6/3/2010
Primary
Secondary
Concomitant
Somnolence Other Serious 5/30/2010 61 Female 6/9/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 5/1/2010 58 Male 6/11/2010 Pharmacist Japan
Primary
Concomitant
Somnolence Other Serious 5/30/2010 61 Female 6/18/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 5/30/2010 61 Female 7/7/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/22/2010 76 Male 141 lb 7/30/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 11/1/2009 57 Male 130 lb 8/10/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/22/2010 76 Male 141 lb 8/10/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/22/2010 76 Male 141 lb 8/12/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 1/22/2010 76 Male 141 lb 9/16/2010 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 8/24/2010 37 Male 231 lb 10/1/2010 Pharmacist Japan
Primary
Concomitant
Weight Increased Hospitalization 8/24/2010 37 Male 231 lb 10/14/2010 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 1/22/2010 76 Male 141 lb 10/14/2010 Physician Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 10/20/2010 Pharmacist Japan
Primary
Secondary
Lymphocyte Stimulation Test Positive Hospitalization 7/6/2010 11 Male 10/21/2010 Physician Japan
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 10/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 10/26/2010 Physician Japan
Primary
Secondary
Malaise Hospitalization 8/10/2010 76 Male 123 lb 10/29/2010 Physician Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 10/29/2010 Pharmacist Japan
Primary
Secondary
Pneumonia Bacterial Other Serious 4/13/2010 59 Male 11/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 4/13/2010 59 Male 11/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/18/2009 63 Male 110 lb 11/17/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 11/18/2010 79 Male 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
Paronychia Other Serious 9/13/2010 12/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaemia Death 7/16/2009 60 Female 149 lb 1/13/2011 Pharmacist Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 11/16/2010 79 Male 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 8/10/2010 76 Male 123 lb 1/24/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Life Threatening 1/6/2011 83 Female 82 lb 1/25/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 9/13/2010 67 Female 95 lb 1/31/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 3/9/2009 82 Female 84 lb 9/28/2009 Consumer Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/18/2009 63 Male 111 lb 2/8/2011 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 1/6/2011 83 Female 82 lb 2/25/2011 Pharmacist Japan
Primary
Concomitant
General Physical Health Deterioration Death 11/20/2010 99 Male 2/28/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 7/16/2009 60 Female 149 lb 2/28/2011 Pharmacist Japan
Primary
Concomitant
Lymphocyte Stimulation Test Positive Hospitalization 7/6/2010 11 Male 3/14/2011 Physician Japan
Primary
Secondary
Hepatic Function Abnormal Other Serious 6/30/2009 57 Female 121 lb 3/16/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 7/16/2009 60 Female 149 lb 3/15/2011 Japan
Primary
Concomitant
Cardiac Failure Hospitalization 1/6/2011 83 Female 82 lb 3/22/2011 Pharmacist Japan
Primary
Concomitant
Pleural Effusion Hospitalization 3/10/2010 73 Male 134 lb 4/7/2011 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 3/10/2010 73 Male 134 lb 4/11/2011 Physician Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 4/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 1/19/2011 62 Male 4/27/2011 Physician Japan
Primary
Concomitant
Blood Pressure Decreased Life Threatening 11/20/2010 99 Male 5/12/2011 Physician Japan
Primary
Concomitant
Encephalopathy Death 3/18/2011 57 Female 118 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Other Serious 7/18/2009 63 Male 111 lb 5/25/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 3/10/2010 73 Male 134 lb 6/8/2011 Physician Japan
Primary
Concomitant
Hepatic Atrophy Death 4/22/2011 43 Male 6/15/2011 Physician Japan
Primary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious 5/28/2011 20 Female 29 lb 6/17/2011 Physician Japan
Primary
Concomitant
Paronychia Other Serious 9/13/2010 67 Female 95 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Bone Death 1/19/2011 62 Male 6/27/2011 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 6/12/2011 80 Male 120 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Aortic Dissection Hospitalization 7/7/2011 64 Female 129 lb 7/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 4/22/2011 43 Male 7/22/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/21/2010 62 Male 139 lb 7/26/2011 Physician Japan
Primary
Concomitant
Rhinitis Hospitalization 6/12/2011 80 Male 120 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 3/29/2011 56 Male 146 lb 8/8/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Hospitalization 12/17/2009 74 Female 86 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Aortic Dissection Hospitalization 7/7/2011 64 Female 129 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 57 lb 8/24/2011 Physician Japan
Primary
Secondary
Sepsis Hospitalization 6/12/2011 80 Male 120 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Life Threatening 6/20/2011 77 Male 128 lb 8/26/2011 Pharmacist Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/21/2010 62 Male 139 lb 8/31/2011 Physician Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/20/2011 77 Male 128 lb 9/19/2011 Physician Japan
Primary
Concomitant
Aortic Dissection Hospitalization 7/7/2011 64 Female 129 lb 9/19/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 9/13/2010 67 Female 95 lb 9/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haematemesis Other Serious 6/20/2011 77 Male 128 lb 10/4/2011 Physician Japan
Primary
Concomitant
Nikolsky's Sign Other Serious 8/15/2009 45 Male 176 lb 10/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/20/2011 77 Male 128 lb 10/14/2011 Physician Japan
Primary
Concomitant
Drug Reaction With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 12/11/2012 Physician Jp
Primary
Secondary
Drug Reaction With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 12 Male 12/20/2012 Physician Jp
Primary
Secondary
Drug Reaction With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 12 Male 57 lb 3/19/2013 Physician Jp
Primary
Secondary
Drug Reaction With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 12/19/2012 Other Health Professional Jp
Primary
Secondary
White Blood Cell Count Increased Hospitalization 11/11/2011 75 Male 139 lb 11/15/2012 Other Health Professional Jp
Primary
Concomitant
Ovarian Cancer Recurrent Death 8/20/2009 65 Female 128 lb 9/21/2012 Physician Jp
Primary
Concomitant
Pneumonia Staphylococcal Hospitalization 7/7/2012 74 Male 128 lb 12/7/2012 Other Health Professional Jp
Primary
Concomitant
Skin Reaction Hospitalization 5/24/2012 69 Female 106 lb 11/8/2012 Other Health Professional Jp
Primary
Concomitant
Pleural Effusion Other Serious 8/30/2011 43 Male 134 lb 10/26/2012 Physician Jp
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/25/2011 75 Male 110 lb 11/6/2012 Physician Jp
Primary
Concomitant

Drug Data