Bevacizumab combined with Temsirolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 7/19/2008 Female 134 lb 8/1/2008 Physician Hungary
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2008 Female 134 lb 8/5/2008 Physician Hungary
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/10/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 8/4/2008 Male 9/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/10/2008 Male 9/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/10/2008 Female 226 lb 9/22/2008 Physician Hungary
Primary
Secondary
Concomitant
Viral Infection Hospitalization 9/10/2008 Female 226 lb 9/29/2008 Physician Hungary
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2008 Female 134 lb 10/10/2008 Physician Hungary
Primary
Secondary
Concomitant
Viral Pharyngitis Hospitalization 10/12/2008 Female 207 lb 10/28/2008 Physician Hungary
Primary
Secondary
Concomitant
Viral Pharyngitis Hospitalization 10/12/2008 Female 207 lb 11/3/2008 Physician Hungary
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 9/15/2008 Male 11/7/2008 Consumer United Kingdom
Primary
Secondary
Malnutrition Hospitalization 10/24/2008 Male 11/11/2008 Physician United Kingdom
Primary
Secondary
Malnutrition Hospitalization 10/24/2008 Male 11/18/2008 Physician United Kingdom
Primary
Secondary
Ketosis Hospitalization 11/12/2008 Female 11/26/2008 Physician United Kingdom
Primary
Secondary
General Physical Condition Abnormal Hospitalization 8/12/2008 Male 12/8/2008 Consumer United Kingdom
Primary
Secondary
Hypomagnesaemia Other Serious 11/11/2008 54 Female 12/9/2008 Physician United States
Primary
Concomitant
Hypomagnesaemia Other Serious 11/11/2008 54 Female 12/9/2008 Physician United States
Primary
Secondary
Retching Other Serious 11/12/2008 Female 12/9/2008 Physician United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 11/12/2008 Female 12/11/2008 Consumer United States
Primary
Secondary
Concomitant
Death Death 8/8/2008 12/12/2008 Physician United States
Primary
Secondary
Arrhythmia Hospitalization 5/16/2008 Male 12/15/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 11/26/2008 Female 12/16/2008 Consumer United Kingdom
Primary
Secondary
General Physical Condition Abnormal Hospitalization 8/12/2008 Male 12/17/2008 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 11/12/2008 Female 12/18/2008 Consumer United States
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 5/16/2008 Male 12/22/2008 Physician United States
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Bronchospasm Other Serious 12/23/2008 Female 110 lb 1/8/2009 Physician Serbia
Primary
Secondary
Concomitant
Blood Magnesium Decreased Other Serious 11/11/2008 54 Female 121 lb 1/14/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 12/9/2008 Male 162 lb 1/14/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Bronchospasm Other Serious 12/29/2008 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Bronchospasm Other Serious 12/29/2008 Female 110 lb 1/22/2009 Physician Serbia
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 12/9/2008 Male 1/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/10/2009 Male 1/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Bronchospasm Other Serious 12/29/2008 Female 2/5/2009 Consumer United States
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 1/10/2009 Male 2/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Protein Urine Present Hospitalization 1/20/2009 Male 181 lb 2/23/2009 Physician France
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 2/2/2009 67 Female 2/27/2009 Physician United States
Primary
Secondary
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/5/2009 Male 157 lb 3/10/2009 Physician Czech Republic
Primary
Secondary
International Normalised Ratio Increased Other Serious 2/6/2009 3/10/2009 Physician United States
Primary
Secondary
Anaemia Hospitalization 3/5/2009 Male 3/20/2009 Consumer United Kingdom
Primary
Secondary
Diabetes Mellitus Hospitalization 1/20/2009 Male 181 lb 3/24/2009 Physician France
Primary
Secondary
Concomitant
Pharyngitis Hospitalization 3/21/2009 Female 138 lb 3/26/2009 Physician South Africa
Primary
Secondary
Concomitant
Proctitis Hospitalization 2/3/2009 Male 151 lb 4/6/2009 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/4/2009 Male 126 lb 4/7/2009 Physician Czech Republic
Primary
Secondary
Anal Abscess Hospitalization 3/26/2009 Male 212 lb 4/9/2009 Physician Spain
Primary
Secondary
Anaemia Hospitalization 3/4/2009 Male 126 lb 4/13/2009 Physician Czech Republic
Primary
Secondary
Pharyngitis Hospitalization 3/21/2009 Female 138 lb 4/13/2009 Physician South Africa
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/15/2009 50 Male 4/14/2009 Physician United States
Primary
Secondary
Proctitis Hospitalization 2/3/2009 Male 4/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/5/2009 Male 157 lb 4/16/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/20/2009 50 Male 4/16/2009 Physician United States
Primary
Secondary
Pulmonary Embolism Other Serious 11/12/2008 Female 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Proctitis Hospitalization 2/3/2009 Male 151 lb 4/23/2009 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/5/2009 Male 157 lb 4/28/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Proctitis Hospitalization 2/3/2009 Male 4/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/5/2009 Male 157 lb 5/4/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Sepsis Death 4/29/2009 Male 162 lb 5/11/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/23/2009 Male 157 lb 5/11/2009 Physician Canada
Primary
Secondary
Concomitant
Peritonitis Death 4/29/2009 Male 162 lb 5/12/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 3/26/2009 Male 212 lb 5/12/2009 Physician Spain
Primary
Concomitant
Pneumonia Other Serious 4/23/2009 Male 157 lb 5/15/2009 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 3/6/2009 Male 180 lb 5/18/2009 Physician Spain
Primary
Secondary
Peritonitis Hospitalization 4/27/2009 Male 162 lb 5/20/2009 Physician Korea, Republic Of
Primary
Concomitant
Tumour Haemorrhage Life Threatening 12/9/2008 Male 162 lb 5/21/2009 Physician United States
Primary
Secondary
Concomitant
Pharyngitis Hospitalization 3/21/2009 Female 138 lb 5/26/2009 Physician South Africa
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 12/9/2008 Male 5/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 5/13/2009 Male 5/27/2009 Physician Poland
Primary
Secondary
Concomitant
Pain In Jaw Hospitalization 5/3/2009 79 Female 5/27/2009 Physician United States
Primary
Secondary
Respiratory Failure Hospitalization 5/6/2009 Male 180 lb 5/29/2009 Physician Spain
Primary
Secondary
Pulmonary Embolism Other Serious 11/12/2008 Female 5/29/2009 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Death 79 Female 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/14/2009 Male 5/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 5/14/2009 Male 6/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 79 Female 6/9/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 5/19/2009 Male 6/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/27/2009 Male 6/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Confusional State Other Serious 5/27/2009 Male 150 lb 6/16/2009 Physician Czech Republic
Primary
Concomitant
Death Death 5/25/2009 62 Male 6/16/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/6/2009 Male 179 lb 6/17/2009 Physician Spain
Primary
Secondary
Diarrhoea Other Serious 5/13/2009 Male 139 lb 6/17/2009 Physician Poland
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/12/2009 Male 152 lb 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/8/2009 Male 117 lb 6/19/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/5/2009 Male 6/23/2009 Consumer United Kingdom
Primary
Secondary
Diarrhoea Other Serious 5/13/2009 Male 139 lb 6/24/2009 Physician Poland
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/27/2009 Male 197 lb 6/24/2009 Physician Australia
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 5/9/2009 Male 6/25/2009 Consumer United States
Primary
Secondary
Interstitial Lung Disease Other Serious 5/27/2009 Male 6/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 6/21/2009 Male 95 lb 6/29/2009 Physician India
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/6/2009 Female 148 lb 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Blood Magnesium Decreased Other Serious 11/11/2008 54 Female 121 lb 7/1/2009 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 6/21/2009 Male 95 lb 7/1/2009 Physician India
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/27/2009 Male 7/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 4/27/2009 Male 7/2/2009 Physician United Kingdom
Primary
Secondary
Subcutaneous Abscess Hospitalization 5/28/2009 Male 211 lb 7/8/2009 Physician United States
Primary
Secondary
Ileus Paralytic Hospitalization 6/30/2009 Male 159 lb 7/8/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/8/2009 Female 117 lb 7/9/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Death Death 6/21/2009 Male 7/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Ileus Paralytic Hospitalization 6/30/2009 Male 159 lb 7/16/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Arrest Death 5/19/2009 Male 7/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/19/2009 50 Male 157 lb 7/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/1/2009 60 Male 7/22/2009 Other Health Professional Portugal
Primary
Concomitant
Osteonecrosis Other Serious 3/19/2009 50 Male 157 lb 7/22/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 5/28/2009 Male 211 lb 7/24/2009 Physician United States
Primary
Secondary
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 7/20/2009 Male 237 lb 7/30/2009 Physician United States
Primary
Secondary
Proctalgia Hospitalization 7/22/2009 Male 213 lb 7/30/2009 Physician United States
Primary
Secondary
Proctalgia Hospitalization 7/22/2009 Male 213 lb 7/30/2009 Physician United States
Primary
Secondary
Ileus Paralytic Hospitalization 7/1/2009 Male 159 lb 7/31/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 7/23/2009 Male 205 lb 7/31/2009 Physician Poland
Primary
Secondary
Perirectal Abscess Hospitalization 7/19/2009 Female 223 lb 8/4/2009 Physician Poland
Primary
Secondary
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 7/23/2009 Male 205 lb 8/4/2009 Physician Poland
Primary
Secondary
Infection Other Serious 6/12/2009 Male 152 lb 8/5/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/22/2009 Male 213 lb 8/6/2009 Physician United States
Primary
Secondary
Sudden Death Death 6/21/2009 Male 95 lb 8/7/2009 Physician India
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/5/2009 Male 171 lb 8/7/2009 Physician Spain
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 7/23/2009 Male 205 lb 8/7/2009 Physician Poland
Primary
Secondary
Anal Fissure Hospitalization 7/23/2009 Male 205 lb 8/14/2009 Physician Poland
Primary
Secondary
Perirectal Abscess Hospitalization 7/19/2009 Female 223 lb 8/14/2009 Physician Poland
Primary
Secondary
Renal Failure Hospitalization 8/5/2009 Male 8/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Anal Fistula Hospitalization 8/8/2009 Male 205 lb 8/18/2009 Physician Argentina
Primary
Secondary
Renal Failure Hospitalization 8/5/2009 Male 171 lb 8/19/2009 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 5/14/2009 Male 8/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 7/23/2009 Male 205 lb 8/20/2009 Physician Poland
Primary
Secondary
Anal Fistula Hospitalization 8/8/2009 Male 205 lb 8/21/2009 Physician Argentina
Primary
Secondary
Anal Fissure Hospitalization 7/23/2009 Male 205 lb 8/25/2009 Physician Poland
Primary
Secondary
Pneumonia Other Serious 4/23/2009 Male 169 lb 8/26/2009 Physician Canada
Primary
Secondary
Concomitant
Epistaxis Other Serious 5/3/2009 Female 161 lb 8/26/2009 Physician Slovakia (Slovak Republic)
Primary
Secondary
Headache Hospitalization 8/27/2009 Male 187 lb 9/8/2009 Physician Hungary
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/26/2009 Male 104 lb 9/9/2009 Physician India
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/26/2009 Male 104 lb 9/11/2009 Physician India
Primary
Secondary
Concomitant
Vision Blurred Death 79 Female 148 lb 9/15/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/6/2009 Female 148 lb 9/18/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 12/9/2008 Male 162 lb 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 8/8/2009 Male 185 lb 9/23/2009 Physician Poland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/14/2009 Male 168 lb 9/23/2009 Physician Belgium
Primary
Secondary
Concomitant
Gangrene Hospitalization 7/19/2009 Female 223 lb 9/24/2009 Physician Poland
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/16/2009 69 Male 9/30/2009 Physician United States
Primary
Secondary
Epistaxis Hospitalization 8/16/2009 69 Male 10/1/2009 Physician United States
Primary
Secondary
Epistaxis Other Serious 5/3/2009 Female 161 lb 10/2/2009 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Dizziness Hospitalization 8/8/2009 Male 185 lb 10/6/2009 Physician Poland
Primary
Concomitant
Catheter Site Haemorrhage Other Serious 10/1/2009 Male 159 lb 10/7/2009 Physician Poland
Primary
Secondary
Concomitant
Cardiac Arrest Death 5/25/2009 Male 10/7/2009 Physician United States
Primary
Secondary
Anaemia Hospitalization 10/5/2009 Male 146 lb 10/9/2009 Physician Poland
Primary
Secondary
Concomitant
Anorectal Cellulitis Hospitalization 8/8/2009 Male 205 lb 10/9/2009 Physician Argentina
Primary
Secondary

Drug Data