Bevacizumab combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombotic Thrombocytopenic Purpura Death 8/22/2006 Male 12/15/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Decreased Death 8/22/2006 Male 12/26/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Synovitis Hospitalization 10/30/2006 71 Female 1/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 2/1/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/15/2006 61 Male 250 lb 3/9/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/18/2007 79 Male 141 lb 3/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 2/21/2007 77 Male 211 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Shock Hospitalization 2/21/2007 Male 3/28/2007 Physician United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 1/30/2007 74 Male 227 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Shock Death 2/21/2007 77 Male 211 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/30/2007 Male 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/1/2007 54 Female 3/26/2007 Physician Peru
Primary
Secondary
Concomitant
Septic Shock Death 2/21/2007 Male 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 2/27/2007 63 Female 401 lb 4/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 4/18/2007 Consumer United States
Primary
Secondary
Concomitant
Death Death 11/2/2006 Female 195 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/30/2007 74 Male 227 lb 4/20/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/30/2007 Male 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Tachyarrhythmia Death 11/2/2006 Female 195 lb 4/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/18/2007 73 Male 163 lb 4/23/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 4/9/2007 65 Male 184 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/10/2007 Male 184 lb 5/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/9/2007 Male 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/14/2007 79 Male 130 lb 5/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 5/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 11/2/2006 Female 195 lb 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 5/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 Male 250 lb 5/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/16/2007 81 Male 181 lb 5/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 5/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/21/2006 51 Female 139 lb 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 6/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 6/12/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/21/2006 51 Female 139 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 4/7/2007 32 Female 182 lb 7/13/2007 Physician Australia
Primary
Secondary
Concomitant
Death Death 7/4/2007 Male 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 Female 152 lb 7/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 4/7/2007 Female 7/23/2007 Physician Australia
Primary
Secondary
Concomitant
Neoplasm Progression Death 7/4/2007 Male 7/23/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 7/24/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/21/2006 51 Female 139 lb 7/19/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 7/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/17/2007 Physician Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 Female 152 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/23/2007 Physician Austria
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 7/29/2007 Male 204 lb 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 7/29/2007 Male 204 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 7/29/2007 Male 204 lb 10/11/2007 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Hospitalization 10/10/2007 Male 162 lb 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 9/26/2007 62 Female 11/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/23/2007 73 Male 165 lb 11/12/2007 Physician Canada
Primary
Secondary
Concomitant
Syncope Other Serious 1/23/2006 Female 203 lb 11/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 11/17/2007 Male 128 lb 12/7/2007 Consumer United Kingdom
Primary
Concomitant
Hypersensitivity Hospitalization 11/9/2007 Female 225 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 9/26/2007 62 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/26/2007 Male 1/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 1/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 1/6/2008 76 Male 175 lb 1/14/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 1/6/2008 Male 175 lb 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/6/2008 76 Male 175 lb 1/22/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 1/6/2008 Male 175 lb 1/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 1/20/2008 Female 128 lb 2/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/18/2008 Male 160 lb 2/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Influenza Hospitalization 2/18/2008 Female 194 lb 2/28/2008 Consumer United States
Primary
Concomitant
Nervous System Disorder Hospitalization 11/17/2007 Male 128 lb 2/28/2008 Consumer United Kingdom
Primary
Concomitant
Hepatorenal Syndrome Hospitalization 1/20/2008 Female 128 lb 3/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2006 Female 3/7/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/26/2007 Male 3/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 3/20/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Male 163 lb 3/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/20/2008 Male 4/3/2008 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/4/2008 United States
Primary
Secondary
Cerebral Haemorrhage Other Serious 6/10/2007 Male 201 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 7/29/2007 Male 204 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/7/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 10/13/2007 Male 176 lb 4/7/2008 Physician United States
Primary
Concomitant
Cerebral Haemorrhage Other Serious 3/13/2008 Female 133 lb 4/8/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 181 lb 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 181 lb 4/18/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2008 4/21/2008 Consumer United States
Primary
Secondary
Peritonitis Hospitalization 2/10/2008 62 Male 158 lb 4/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 5/1/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 5/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neonatal Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 5/6/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 5/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 5/14/2008 United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/12/2008 Male 6/3/2008 Physician Canada
Primary
Secondary
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 6/4/2008 Physician United States
Primary
Secondary
Concomitant
Suture Related Complication Life Threatening 5/18/2008 Female 191 lb 6/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/12/2008 Male 6/5/2008 Consumer United Kingdom
Primary
Secondary
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/12/2008 61 Male 6/6/2008 Other Health Professional Canada
Primary
Secondary
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/9/2008 Physician France
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 6/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 6/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 7/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 7/29/2008 Physician United States
Primary
Secondary
Concomitant
Ataxia Hospitalization 2/11/2008 Female 180 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 8/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tracheo-oesophageal Fistula Other Serious 67 Male 8/11/2008 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 7/22/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/21/2008 Female 120 lb 9/5/2008 Physician United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious 9/9/2008 Female 10/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 10/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/25/2008 Male 11/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/18/2008 Female 191 lb 11/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2008 Female 162 lb 11/14/2008 Consumer United States
Primary
Concomitant
Intestinal Obstruction Other Serious 7/3/2008 Female 238 lb 11/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperparathyroidism Other Serious Female 11/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cellulitis Hospitalization 10/31/2008 Female 269 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 11/24/2008 Male 12/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 5/27/2008 Female 12/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/11/2008 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/18/2008 Female 191 lb 12/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 12/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/18/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 12/24/2008 Physician United States
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 12/31/2007 Male 175 lb 1/6/2009 Physician United States
Primary
Secondary
Concomitant
Otitis Media Hospitalization 10/25/2008 Male 180 lb 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Death 12/31/2007 Male 175 lb 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/5/2009 Female 1/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Otitis Media Hospitalization 10/25/2008 Male 180 lb 2/13/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/5/2009 Female 3/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Myalgia Hospitalization 3/8/2009 Male 143 lb 3/12/2009 Physician India
Primary
Concomitant
Dural Fistula Hospitalization 2/28/2009 Male 238 lb 3/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 9/6/2008 64 NotSpecified 183 lb 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 Male 250 lb 3/16/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 Male 250 lb 3/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data