Bevacizumab combined with Leucovorin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebrovascular Accident Hospitalization 1/5/2006 Male 162 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/20/2005 Male 1/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2006 Male 162 lb 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 1/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Ulcerative Life Threatening 11/12/2005 Female 2/3/2006 Physician France
Primary
Secondary
Syncope Hospitalization 1/23/2006 Female 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Ulcerative Life Threatening 11/12/2005 Female 2/13/2006 Physician France
Primary
Secondary
Myocardial Ischaemia Hospitalization 12/29/2005 2/15/2006 Other Health Professional United States
Primary
Secondary
Peritonitis Life Threatening 7/26/2005 Male 2/20/2006 Other Health Professional Bulgaria
Primary
Secondary
Arterial Thrombosis Hospitalization 2/10/2006 71 Female 168 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 12/2/2005 Male 3/24/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/7/2006 42 Female 3/21/2006 United States
Primary
Secondary
Yawning Other Serious 10/10/2005 54 Female 260 lb 2/15/2006 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 10/22/2006 Male 206 lb 11/2/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2006 64 Male 159 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Performance Status Decreased Hospitalization 10/22/2006 74 Male 206 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/1/2007 Female 9/14/2007 Physician United States
Primary
Secondary
Pulmonary Embolism Life Threatening 9/7/2007 Male 9/21/2007 Physician United Kingdom
Primary
Secondary
Sepsis Hospitalization 7/20/2007 Male 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 7/23/2007 Male 159 lb 9/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Cancer Other Serious Female 144 lb 9/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 4/6/2007 Male 231 lb 9/29/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Life Threatening 8/1/2007 Female 117 lb 10/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Other Serious 7/20/2007 Male 159 lb 10/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Alveolitis Allergic Life Threatening 9/7/2007 Male 10/5/2007 Physician United Kingdom
Primary
Secondary
Oesophagitis Hospitalization 12/28/2005 Male 203 lb 10/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Rectal Abscess Death 8/26/2007 66 Male 10/8/2007 Other Health Professional United States
Primary
Secondary
Oesophagitis Hospitalization 3/10/2006 Male 203 lb 10/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Cancer Other Serious Female 144 lb 10/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Embolism Other Serious 9/7/2007 Male 10/11/2007 Physician United Kingdom
Primary
Secondary
Interstitial Lung Disease Life Threatening 9/24/2007 Female 10/12/2007 Consumer United Kingdom
Primary
Concomitant
Rectal Abscess Death 8/21/2007 Male 170 lb 10/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 8/25/2007 Female 10/16/2007 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 10/3/2007 Female 136 lb 10/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 5/20/2006 Female 147 lb 10/22/2007 Physician United States
Primary
Secondary
Sepsis Hospitalization 7/20/2007 Male 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/10/2007 Female 304 lb 10/25/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/3/2007 Female 136 lb 10/31/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Haemorrhagic Life Threatening 9/25/2007 Female 11/8/2007 Physician United Kingdom
Primary
Secondary
Thrombosis Hospitalization 5/6/2006 Female 11/12/2007 Physician United States
Primary
Secondary
Sepsis Hospitalization 7/20/2007 Male 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 9/23/2007 72 Male 179 lb 12/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Proctalgia Hospitalization 11/28/2007 Male 165 lb 12/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Portal Vein Thrombosis Hospitalization 12/13/2007 Male 12/28/2007 Physician Canada
Primary
Secondary
Concomitant
Proctalgia Hospitalization 11/28/2007 Male 12/31/2007 Physician United States
Primary
Secondary
Concomitant
Gastroenteritis Viral Hospitalization 10/3/2007 Female 136 lb 1/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Portal Vein Thrombosis Hospitalization 12/13/2007 Male 1/9/2008 Physician Canada
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 1/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Flushing Hospitalization 10/17/2007 Female 170 lb 1/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 1/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/24/2007 Male 152 lb 1/29/2008 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 3/19/2008 4/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/26/2008 Female 129 lb 4/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/1/2007 Male 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Arrhythmia Death 1/1/2009 Female 190 lb 1/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious Male 1/30/2009 Consumer United Kingdom
Primary
Secondary
Pyrexia Other Serious 12/18/2008 Male 1/30/2009 Physician Switzerland
Primary
Secondary
Gastroenteritis Hospitalization 12/3/2005 Male 159 lb 2/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 10/6/2009 Male 174 lb 10/28/2009 Consumer United States
Primary
Secondary
Concomitant
Tympanic Membrane Perforation Other Serious 9/5/2006 Male 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 9/17/2009 Male 11/6/2009 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 10/3/2007 Female 136 lb 11/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2008 Male 134 lb 11/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Other Serious 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Diarrhoea Hospitalization 9/29/2008 68 Male 11/11/2009 Consumer United States
Primary
Secondary
Death Death 10/6/2009 Male 174 lb 11/13/2009 Consumer United States
Primary
Secondary
Concomitant
Rectal Perforation Hospitalization 7/15/2005 49 Male 198 lb 6/8/2010 Physician South Africa
Primary
Secondary
Concomitant
Trigger Finger Hospitalization 10/16/2009 61 Male 203 lb 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/4/2010 51 Male 122 lb 11/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/5/2010 68 Male 154 lb 12/3/2010 Physician Spain
Primary
Secondary
Concomitant
Wound Infection Other Serious 12/7/2010 Other Health Professional Spain
Primary
Secondary
Pyrexia Hospitalization 6/4/2010 51 Male 133 lb 12/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 6/4/2010 51 Male 122 lb 12/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/4/2010 51 Male 122 lb 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Other Serious 65 Female 1/19/2011 Physician Canada
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 67 Male 3/1/2011 Other Health Professional United States
Primary
Secondary
Rash Other Serious 10/7/2010 72 Female 3/24/2011 Consumer Canada
Primary
Concomitant
Gastrointestinal Obstruction Hospitalization 10/5/2010 68 Male 154 lb 3/25/2011 Physician Spain
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious 3/29/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Other Serious 4/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Death 51 Male 187 lb 4/13/2011 Other Health Professional United States
Primary
Secondary
Acute Myocardial Infarction Other Serious 4/15/2011 Other Health Professional Italy
Primary
Secondary
Atrial Fibrillation Other Serious 2/23/2009 55 Male 4/20/2011 Consumer Croatia (Local Name: Hrvatska)
Primary
Concomitant
Atrial Fibrillation 2/23/2009 55 Male 4/20/2011 Consumer Croatia (Local Name: Hrvatska)
Primary
Concomitant
Diarrhoea Hospitalization 5/18/2007 56 Male 165 lb 4/22/2011 Physician Germany
Primary
Secondary
Concomitant
Hypoxia Other Serious 71 Male 4/22/2011 Other Health Professional Japan
Primary
Secondary
Muscular Weakness Hospitalization 9/3/2012 82 Male 149 lb 11/1/2012 Physician Us
Primary
Secondary
Tumour Necrosis Hospitalization 64 Female 8/24/2012 Jp
Primary
Secondary
Tunnel Vision Hospitalization 50 Female 9/19/2012 Physician Us
Primary
Secondary
Portal Hypertension Hospitalization 45 Female 9/17/2012 Other Health Professional Us
Primary
Concomitant
Renal Colic Hospitalization 9/10/2012 56 Male 192 lb 12/31/2012 Physician De
Primary
Secondary
Concomitant
Salmonellosis Hospitalization 9/10/2012 71 Male 198 lb 10/19/2012 Physician De
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 7/26/2006 46 Female 157 lb 10/17/2012 Physician Us
Primary
Secondary
Portal Hypertension Hospitalization 45 Female 9/26/2012 Other Health Professional Us
Primary
Concomitant
Sepsis Death 46 Female 9/26/2012 Other Health Professional Us
Primary
Secondary
Sepsis Death 10/2/2012 Other Health Professional It
Primary
Secondary
Pneumonitis Hospitalization 8/29/2012 51 Female 10/5/2012 Physician De
Primary
Secondary
Sepsis Death 57 Male 10/5/2012 Country Not Specified
Primary
Secondary
Portal Hypertensive Gastropathy Hospitalization 45 Female 10/18/2012 Other Health Professional Us
Primary
Concomitant
Neutropenia Hospitalization 9/24/2012 59 Male 11/19/2012 Physician De
Primary
Secondary
Disease Progression Other Serious 60 Female 154 lb 10/18/2012 Physician Br
Primary
Concomitant
Disease Progression Other Serious 66 Male 150 lb 10/19/2012 Physician Br
Primary
Secondary
Disease Progression Hospitalization 10/15/2012 53 Female 159 lb 10/19/2012 Physician Ru
Primary
Concomitant
Pulmonary Oedema Life Threatening 6/4/2010 70 Male 134 lb 10/23/2012 Physician Si
Primary
Concomitant
Vomiting Other Serious 10/26/2012 Other Health Professional Country Not Specified
Primary
Secondary
Disease Progression Other Serious 62 Male 181 lb 10/25/2012 Physician Br
Primary
Secondary
Concomitant
Disease Progression Other Serious 45 Female 123 lb 10/25/2012 Physician Br
Primary
Secondary
Concomitant
Disease Progression Other Serious 67 Male 179 lb 10/30/2012 Physician Br
Primary
Concomitant
Disease Progression Other Serious 45 Male 117 lb 10/30/2012 Physician Br
Primary
Secondary
Disease Progression Other Serious Male 148 lb 10/30/2012 Physician Br
Primary
Concomitant
Weight Fluctuation Death 6/2012 Female 125 lb 10/30/2012 Consumer Us
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Death 10/29/2012 Physician Us
Primary
Secondary
Diarrhoea Death 10/29/2012 Physician Us
Primary
Secondary
Disease Progression Other Serious 76 Female 125 lb 10/31/2012 Physician Br
Primary
Secondary
Uterine Perforation Other Serious 36 Female 11/1/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Paronychia Other Serious 13 Female 10/29/2012 Rs
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/21/2012 72 Male 181 lb 11/9/2012 Physician De
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Death 11/5/2012 Us
Primary
Secondary
Sepsis Death 11/2/2012 Us
Primary
Secondary
Tunnel Vision Hospitalization 50 Female 11/5/2012 Us
Primary
Secondary
Sudden Death Death 11/5/2012 Other Health Professional Us
Primary
Secondary
Diarrhoea Death 11/5/2012 Us
Primary
Secondary
Vomiting Other Serious 11/13/2012 Other Health Professional Country Not Specified
Primary
Secondary
Atrial Fibrillation Hospitalization 10/16/2012 69 Male 289 lb 11/16/2012 Other Health Professional Cz
Primary
Secondary
Concomitant
Disease Progression Other Serious 10/11/2012 61 Female 154 lb 11/19/2012 Physician Ru
Primary
Concomitant
Hepatic Failure Other Serious 11/15/2012 56 Male 130 lb 11/27/2012 Physician Ru
Primary
Concomitant
Atrial Fibrillation Other Serious 10/16/2012 69 Male 289 lb 11/29/2012 Physician Cz
Primary
Secondary
Concomitant
Vomiting Other Serious 71 12/5/2012 Physician Dz
Primary
Concomitant
Vomiting Other Serious 60 12/6/2012 Physician Dz
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 52 Female 146 lb 11/20/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Disease Progression Other Serious 11/19/2012 52 Female 220 lb 12/4/2012 Physician Ru
Primary
Concomitant
Vomiting Other Serious 77 12/7/2012 Physician Dz
Primary
Concomitant
Tooth Loss Other Serious 53 Female 12/12/2012 Other Health Professional Country Not Specified
Primary
Concomitant
No Therapeutic Response Other Serious 12/5/2012 Jp
Primary
Secondary
Concomitant
Vomiting Other Serious 12/5/2012 12/5/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 12/6/2012 Other Health Professional It
Primary
Secondary
Interstitial Lung Disease Death 12/6/2012 Other Health Professional Jp
Primary
Secondary
Thrombocytopenia Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Infection Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Fatigue Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Infection Other Serious 12/6/2012 Jp
Primary
Secondary
Concomitant
Neutropenia Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Neuropathy Peripheral Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Diarrhoea Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Anaemia Other Serious 12/6/2012 Other Health Professional Jp
Primary
Secondary
Myocardial Infarction Death 12/10/2012 Other Health Professional It
Primary
Secondary
Lower Gastrointestinal Haemorrhage Death 12/21/2012 Physician Fr
Primary
Secondary

Drug Data