Bevacizumab combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Non-cardiac Chest Pain Required Intervention 12/29/2005 Male 203 lb 1/5/2006 United States
Primary
Secondary
Vomiting Other Serious 1/7/2006 Female 108 lb 1/16/2006 United States
Primary
Secondary
Non-cardiac Chest Pain Disability 8/31/2005 51 Female 185 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Nephrolithiasis Hospitalization 2/17/2006 46 Female 129 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/17/2005 73 Male 141 lb 3/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/11/2005 Female 93 lb 3/8/2006 Pharmacist Ireland
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 3/10/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 3/2/2006 Male 223 lb 3/9/2006 United States
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 8/6/2005 Male 3/14/2006 Physician Germany
Primary
Secondary
Concomitant
Pruritus Other Serious 8/5/2005 64 Male 153 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Arrhythmia Hospitalization 2/28/2006 Male 3/15/2006 Physician Canada
Primary
Secondary
Colitis Ulcerative Life Threatening 11/12/2005 Female 3/16/2006 Physician France
Primary
Secondary
Tremor Life Threatening 2/14/2006 Male 3/16/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 3/21/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/22/2005 61 Female 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Required Intervention 6/9/2006 56 Male 176 lb 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Death 11/1/2005 Male 10/6/2006 Physician United States
Primary
Secondary
Sudden Death Death 9/9/2006 Female 10/10/2006 Other Health Professional United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/31/2006 77 Female 10/6/2006 United States
Primary
Secondary
Thrombosis Hospitalization 9/4/2006 Male 10/16/2006 Other Health Professional United States
Primary
Secondary
Intestinal Perforation Life Threatening 9/22/2005 Female 10/17/2006 Physician Greece
Primary
Secondary
Mallory-weiss Syndrome Hospitalization 8/25/2006 Female 10/23/2006 Physician
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/31/2006 77 Female 10/25/2006 Physician United States
Primary
Secondary
Neutropenia Hospitalization 9/25/2006 11/10/2006 Other Health Professional United States
Primary
Secondary
Stomatitis Other Serious 8/2/2006 Male 150 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/11/2006 Male 11/15/2006 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Life Threatening 1/19/2006 Female 11/17/2006 Physician Australia
Primary
Secondary
Concomitant
Anaemia Hospitalization 10/5/2006 74 Male 206 lb 11/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 20 Male 11/30/2006
Primary
Secondary
Gastroenteritis Hospitalization 11/8/2006 73 Male 183 lb 12/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Ascites Life Threatening 7/7/2006 Male 148 lb 12/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Peritoneal Neoplasm Life Threatening 7/7/2006 Male 12/7/2006 Physician Japan
Primary
Secondary
Subclavian Vein Thrombosis Hospitalization 8/19/2005 Male 12/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 10/22/2006 Male 206 lb 12/11/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/8/2006 74 Male 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Necrosis Ischaemic Other Serious 57 Male 1/15/2007
Primary
Secondary
Intestinal Perforation Life Threatening 10/18/2006 61 Male 172 lb 1/16/2007 Other Health Professional France
Primary
Secondary
Death Death 1/22/2007 Female 105 lb 1/25/2007 Physician United States
Primary
Concomitant
Toe Amputation Other Serious 57 Male 1/29/2007 Switzerland
Primary
Secondary
Myocardial Infarction Life Threatening 1/24/2007 Female 112 lb 1/29/2007 Physician United States
Primary
Secondary
Anal Fissure Hospitalization 11/9/2006 Male 1/29/2007 Physician Australia
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 1/24/2007 Female 112 lb 2/5/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 1/8/2007 74 Male 1/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Trismus Life Threatening 1/24/2007 Male 2/1/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/20/2006 Female 147 lb 2/16/2007 Physician United States
Primary
Secondary
Dehydration Hospitalization 2/4/2006 Male 2/16/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Trismus Life Threatening 1/24/2007 Male 2/19/2007 Physician United States
Primary
Concomitant
Death Death 1/22/2007 Female 105 lb 1/25/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 5/20/2006 Female 147 lb 3/6/2007 Physician United States
Primary
Secondary
Perianal Abscess Hospitalization 1/9/2007 Male 3/12/2007 Physician Australia
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/10/2007 56 Male 3/9/2007 Physician United States
Primary
Secondary
Confusional State Other Serious 3/6/2007 Female 128 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 3/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 2/16/2007 60 Female 3/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/18/2007 79 Male 141 lb 3/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Fistula Hospitalization 6/14/2006 Female 154 lb 3/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Trismus Life Threatening 1/24/2007 Male 2/19/2007 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death 2/16/2007 Female 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/18/2007 79 Male 141 lb 3/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 3/1/2007 Male 4/6/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Angioedema Life Threatening 5/5/2006 Female 4/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 2/17/2007 Male 142 lb 4/11/2007 Consumer United States
Primary
Concomitant
Malaise Hospitalization 1/2/2007 Female 146 lb 4/11/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/8/2006 Male 183 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Palpitations Other Serious 7/12/2006 Male 4/17/2007 Physician
Primary
Concomitant
Thrombocytopenia Other Serious 52 Male 4/17/2007 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 3/18/2007 Male 198 lb 4/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 4/18/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/9/2006 Female 157 lb 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Cyst Hospitalization 4/6/2007 51 Male 4/12/2007 Physician United States
Primary
Secondary
Pericardial Effusion Hospitalization 8/6/2006 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/6/2006 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 2/17/2007 Male 142 lb 4/24/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/8/2006 Female 157 lb 4/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/24/2007 Female 112 lb 4/27/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/14/2007 79 Male 130 lb 5/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/8/2006 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Hiccups Other Serious 4/5/2007 Male 147 lb 5/2/2007 Physician France
Primary
Secondary
Pyrexia Hospitalization 3/18/2007 Male 198 lb 5/2/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/14/2007 79 Male 130 lb 5/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/15/2007 Male 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 3/18/2007 Male 198 lb 5/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 6/14/2006 Male 137 lb 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 5/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Enteritis Hospitalization 4/30/2007 49 Female 135 lb 5/10/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 6/14/2006 Male 5/11/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Cholangitis Hospitalization 4/11/2007 Female 5/11/2007 Physician United States
Primary
Secondary
Thrombophlebitis Hospitalization 4/19/2007 Male 5/11/2007 Physician France
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/27/2007 Female 142 lb 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Life Threatening 10/25/2006 Female 5/15/2007 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/2/2007 Male 149 lb 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 5/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 2/16/2007 60 Female 5/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 4/19/2007 Male 5/22/2007 Physician France
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/27/2007 Female 142 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 5/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Cyst Other Serious 4/6/2007 51 Male 5/31/2007 Other Health Professional United States
Primary
Secondary
Diarrhoea Hospitalization 3/24/2007 77 Male 236 lb 6/5/2007 Consumer United States
Primary
Secondary
Concomitant
Cholangitis Hospitalization 4/11/2007 Female 6/5/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 3/18/2007 Male 198 lb 6/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 6/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 4/19/2007 Male 6/12/2007 Physician France
Primary
Secondary
Concomitant
Diabetic Cardiomyopathy Hospitalization 10/10/2006 Male 6/12/2007 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 3/14/2007 Male 142 lb 6/12/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Soft Tissue Disorder Death 8/10/2006 46 Male 5/29/2007 United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 4/23/2007 Female 6/15/2007 Physician United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 5/4/2006 Male 6/25/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 1/24/2007 Female 112 lb 6/28/2007 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 7/3/2007 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 7/3/2007 Physician Israel
Primary
Concomitant
Interacting
Confusional State Other Serious 3/6/2007 Female 128 lb 7/5/2007 Consumer United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 4/11/2007 Female 145 lb 7/9/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/10/2006 68 Male 140 lb 7/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/19/2007 53 Female 139 lb 7/19/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/13/2007 Male 185 lb 7/16/2007 Physician United States
Primary
Secondary
Sepsis Hospitalization 6/19/2007 53 Female 139 lb 7/20/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 6/4/2007 Male 7/24/2007 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 5/1/2005 Female 128 lb 7/24/2007 Consumer Switzerland
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious Female 7/25/2007 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 8/1/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/28/2007 Female 8/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Nasal Septum Perforation Other Serious 12/1/2006 53 Male 8/10/2007 Consumer United States
Primary
Concomitant
Sepsis Death 7/23/2007 Male 159 lb 8/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Death 7/6/2007 55 Male 8/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 10/21/2006 Female 8/16/2007 Physician Brazil
Primary
Secondary
Bone Marrow Failure Hospitalization 10/21/2006 Female 149 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/3/2007 Female 200 lb 8/17/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 8/20/2007 Physician United States
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Death 7/23/2007 Male 159 lb 8/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Abscess Hospitalization 8/15/2007 49 Female 127 lb 8/16/2007 Physician United States
Primary
Secondary
Chest Pain Hospitalization 5/1/2005 Female 128 lb 8/24/2007 Consumer Switzerland
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 8/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 7/19/2007 Female 127 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/3/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/3/2007 Physician United States
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Death 7/23/2007 Male 159 lb 9/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 9/6/2007 Physician United States
Primary
Secondary
Concomitant
Neuropathy Other Serious 39 Male 9/6/2007 Physician France
Primary
Concomitant
Pulmonary Hypertension Other Serious 2/2/2006 Male 9/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/1/2007 Female 117 lb 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 7/23/2007 Male 159 lb 9/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data