Bevacizumab combined with Lactulose

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Hospitalization 11/4/2005 57 Female 1/27/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/14/2006 59 Male 11/7/2006 Physician Netherlands
Primary
Secondary
Concomitant
Proteinuria Hospitalization 5/30/2006 65 Female 128 lb 11/13/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/28/2006 Female 113 lb 11/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2006 64 Male 159 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/1/2006 52 Female 110 lb 12/28/2006 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 6/1/2006 52 Female 110 lb 1/15/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 6/1/2006 52 Female 110 lb 1/19/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/20/2007 Male 254 lb 4/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 Male 172 lb 5/17/2007 United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/25/2006 47 Female 203 lb 6/13/2007 Physician Australia
Primary
Secondary
Concomitant
Sepsis Death 2/22/2007 Male 7/23/2007 Physician United States
Primary
Concomitant
Cardiac Arrest Death 7/5/2007 Male 175 lb 8/2/2007 Physician United States
Primary
Secondary
Concomitant
Ascites Hospitalization 8/10/2007 72 Male 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 10/6/2007 Female 138 lb 10/16/2007 Other Health Professional United States
Primary
Concomitant
Pneumopericardium Hospitalization 8/10/2007 72 Male 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 8/10/2007 72 Male 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Pneumopericardium Hospitalization 8/12/2007 72 Male 11/22/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/12/2007 72 Male 11/27/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/25/2006 47 Female 203 lb 12/13/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/12/2007 Female 1/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/19/2007 Female 1/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/12/2006 Female 2/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/12/2006 Female 2/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 3/13/2008 Physician United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 8/4/2007 61 Male 145 lb 3/18/2008 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/8/2008 Male 137 lb 5/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/18/2006 Female 99 lb 8/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 8/14/2006 Female 99 lb 8/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/5/2008 Male 227 lb 8/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/30/2006 Male 154 lb 11/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 5/20/2008 Female 12/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/2/2005 Male 12/18/2008 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/6/2009 Female 2/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/6/2009 Female 3/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 12/19/2008 59 Male 146 lb 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 3/11/2008 46 Female 4/28/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/15/2009 Male 136 lb 5/18/2009 Physician Germany
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/15/2009 Male 136 lb 5/19/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/15/2009 Male 136 lb 5/29/2009 Physician Germany
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 2/14/2009 Male 229 lb 6/2/2009 Consumer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/13/2009 Male 136 lb 6/2/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 6/2/2009 Female 6/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 6/21/2009 Male 95 lb 6/29/2009 Physician India
Primary
Secondary
Concomitant
Sudden Death Death 6/21/2009 Male 95 lb 7/1/2009 Physician India
Primary
Secondary
Concomitant
Death Death 6/21/2009 Male 7/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 6/21/2009 Male 95 lb 8/7/2009 Physician India
Primary
Secondary
Concomitant
Death Death 10/6/2007 Female 138 lb 8/7/2009 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 3/13/2009 Male 136 lb 8/19/2009 Physician Germany
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 10/6/2007 Female 138 lb 8/31/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/23/2009 Female 10/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/25/2009 Female 10/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Death Male 136 lb 11/6/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/25/2009 Female 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 10/27/2009 Female 11/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 5/20/2008 Female 11/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/25/2009 Female 11/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/2/2009 Female 12/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/25/2009 Female 12/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rectal Perforation Hospitalization 12/13/2009 Female 1/19/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pneumopericardium Hospitalization 7/31/2007 Male 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Pneumopericardium Hospitalization 7/31/2007 72 Male 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Other Serious 12/18/2009 Female 112 lb 2/2/2010 Physician United States
Primary
Concomitant
Vena Cava Thrombosis Other Serious 12/18/2009 Female 112 lb 2/5/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/18/2009 Female 112 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Peripheral Ischaemia Life Threatening 10/1/2008 Female 119 lb 3/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/23/2010 Female 119 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 Female 124 lb 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Death Death 3/25/2010 67 Male 138 lb 4/1/2010 Consumer United States
Primary
Secondary
Concomitant
Haematemesis Other Serious 3/25/2010 67 Male 138 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Fall Hospitalization 4/1/2010 71 Male 113 lb 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 3/25/2010 67 Male 138 lb 4/20/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Metastases To Bone Hospitalization 4/1/2010 71 Male 4/27/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/12/2010 46 Female 124 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 3/5/2010 73 Male 108 lb 4/28/2010 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 4/1/2010 71 Male 113 lb 5/3/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 3/25/2010 67 Male 138 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 3/25/2010 67 Male 138 lb 5/11/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 4/1/2010 71 Male 114 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 3/25/2010 67 Male 138 lb 5/19/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 3/25/2010 67 Male 138 lb 5/21/2010 Consumer United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 4/13/2010 60 Male 184 lb 5/26/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 3/25/2010 67 Male 138 lb 6/1/2010 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 5/26/2010 57 Male 137 lb 6/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Death 8/15/2008 50 Male 243 lb 6/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 5/26/2010 57 Male 136 lb 6/15/2010 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 6/15/2010 57 136 lb 6/28/2010 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 5/26/2010 57 Male 136 lb 7/9/2010 Physician Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/16/2010 84 Male 185 lb 7/23/2010 Physician Canada
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/16/2010 84 Male 185 lb 7/27/2010 Physician Canada
Primary
Secondary
Concomitant
Proctalgia Hospitalization 2/24/2010 74 Female 7/29/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/1/2010 71 Male 113 lb 7/30/2010 Physician United States
Primary
Secondary
Concomitant
Proctalgia Hospitalization 2/1/2010 74 Female 239 lb 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/20/2010 71 Male 146 lb 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 7/20/2010 71 Male 146 lb 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 5/26/2010 57 Male 137 lb 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/20/2010 71 Male 146 lb 8/5/2010 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 5/26/2010 57 Male 136 lb 8/6/2010 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 7/7/2010 48 Male 148 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/28/2010 64 Male 240 lb 8/9/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/1/2010 71 Male 114 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 7/7/2010 48 Male 153 lb 8/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 5/26/2010 57 Male 136 lb 8/20/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/20/2010 71 Male 146 lb 8/26/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 64 Female 161 lb 9/1/2010 Lawyer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 7/28/2010 64 Male 240 lb 9/7/2010 Physician Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/16/2010 84 Male 185 lb 9/8/2010 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Life Threatening 10/5/2009 61 Female 9/14/2010 Physician United States
Primary
Secondary
Concomitant
Aphasia Hospitalization 9/7/2010 64 Male 172 lb 9/15/2010 Physician Netherlands
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 10/5/2010 79 Male 220 lb 10/14/2010 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 9/1/2009 63 Female 10/21/2010 Other Health Professional France
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/7/2010 64 Male 170 lb 11/1/2010 Physician Netherlands
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/7/2010 64 Male 170 lb 11/4/2010 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 9/4/2010 42 Male 399 lb 11/15/2010 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 11/1/2007 64 Female 161 lb 11/22/2010 Lawyer United States
Primary
Concomitant
Death Death 10/22/2010 51 Male 190 lb 11/24/2010 Consumer Canada
Primary
Concomitant
Somnolence Hospitalization 11/15/2010 47 Male 155 lb 12/2/2010 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 12/16/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 7/5/2007 59 Male 175 lb 12/30/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 7/5/2007 59 Male 175 lb 1/4/2011 Physician United States
Primary
Secondary
Concomitant
Phlebitis Hospitalization 12/23/2010 54 Male 181 lb 1/5/2011 Consumer Canada
Primary
Concomitant
Diverticulitis Other Serious 12/23/2010 54 Male 181 lb 1/14/2011 Consumer Canada
Primary
Concomitant
Large Intestine Perforation Death 9/7/2010 64 Male 223 lb 2/1/2011 Physician United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Other Serious 10/4/2004 57 Male 212 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Gait Disturbance Death 10/4/2004 57 Male 212 lb 6/13/2011 Other Health Professional United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 7/1/2011 24 Female 7/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Gallbladder Disorder Hospitalization 7/1/2011 24 Female 7/27/2011 Other Health Professional Canada
Primary
Concomitant
Blood Creatinine Increased Hospitalization 6/22/2011 67 Female 8/18/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 6/22/2011 67 Female 176 lb 11/8/2011 Physician United States
Primary
Secondary
Concomitant
Metastatic Renal Cell Carcinoma Death 12/7/2011 68 Male 121 lb 12/8/2011 Consumer United States
Primary
Concomitant
Oesophagitis Hospitalization 12/4/2011 63 Male 136 lb 1/5/2012 Physician Austria
Primary
Secondary
Concomitant
General Physical Condition Abnormal Hospitalization 8/6/2012 70 Male 151 lb 8/16/2012 Physician Germany
Primary
Secondary
Concomitant
General Physical Condition Abnormal Hospitalization 8/6/2012 70 Male 152 lb 8/23/2012 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/11/2010 53 Female 101 lb 11/21/2012 Consumer Us
Primary
Secondary
Concomitant
General Physical Condition Abnormal Hospitalization 8/6/2012 70 Male 152 lb 9/13/2012 Physician De
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/17/2012 56 Male 165 lb 4/10/2013 Physician Us
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 10/17/2012 56 Male 164 lb 4/8/2013 Physician Us
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 7/30/2011 76 Female 2/26/2013 Physician Nl
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/7/2010 10 Male 42 lb 4/24/2013 Physician Fr
Primary
Secondary
Concomitant
Venous Occlusion Hospitalization 1/10/2013 45 Female 236 lb 1/24/2013 Physician Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/1/2013 69 Male 119 lb 7/3/2013 Physician De
Primary
Concomitant
Disease Progression Death Female 8/27/2013 Physician Ie
Primary
Secondary
Concomitant

Drug Data