Bevacizumab combined with Folinic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ulcer Death 10/27/2005 Male 1/5/2006 Other Health Professional United States
Primary
Secondary
Shock Death 10/27/2005 Male 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/23/2006 77 Female 9/22/2006 United States
Primary
Secondary
Pneumatosis Intestinalis Hospitalization 11/24/2006 72 Female 12/18/2006 United States
Primary
Secondary
Concomitant
Short-bowel Syndrome Hospitalization 11/24/2006 72 Female 12/29/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/24/2006 72 Female 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Toe Amputation Other Serious 57 Male 12/28/2006 Switzerland
Primary
Secondary
Dyspnoea Death 10/15/2006 Female 1/9/2007 Other Health Professional United States
Primary
Secondary
Atrial Fibrillation Hospitalization 12/11/2006 Male 1/11/2007 Physician United States
Primary
Secondary
Concomitant
Short-bowel Syndrome Hospitalization 11/24/2006 72 Female 1/10/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 10/15/2006 Female 1/17/2007 Other Health Professional United States
Primary
Secondary
Hypomagnesaemia Hospitalization 3/14/2006 Male 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/2/2006 Female 2/2/2007 Physician United States
Primary
Secondary
Concomitant
Deafness Unilateral Other Serious 1/17/2007 70 Male 1/26/2007 United States
Primary
Secondary
Urinary Retention Hospitalization 6/7/2005 Male 2/26/2007 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 2/10/2007 68 Male 221 lb 3/2/2007 United States
Primary
Secondary
Drug Dose Omission Other Serious 1/17/2007 70 Male 3/6/2007 Other Health Professional United States
Primary
Secondary
Sudden Cardiac Death Death 2/16/2007 0 Female 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 12/11/2006 Male 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Pain Death 2/18/2007 71 Male 3/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Death 2/18/2007 71 Male 3/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Death 10/15/2006 Female 5/14/2007 United States
Primary
Secondary
Hypotension Hospitalization 3/2/2007 Male 148 lb 5/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Local Swelling Hospitalization Female 124 lb 5/16/2007 Consumer United Kingdom
Primary
Secondary
Vena Cava Thrombosis Hospitalization Female 124 lb 5/30/2007 Consumer United Kingdom
Primary
Secondary
Colitis Hospitalization 1/11/2007 68 Male 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Death 10/15/2006 Female 166 lb 6/12/2007 Consumer United States
Primary
Secondary
Dyspnoea Death 10/15/2006 Female 166 lb 6/12/2007 Consumer United States
Primary
Secondary
Ventricular Fibrillation Death 1/19/2005 Male 6/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 3/2/2007 Male 148 lb 6/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Haemorrhage Hospitalization 10/8/2005 Female 7/23/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/24/2006 72 Female 7/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 8/21/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Neuropathy Life Threatening 2/28/2007 Female 112 lb 8/21/2007 Physician Germany
Primary
Concomitant
Anaemia Hospitalization 8/9/2007 Female 154 lb 8/24/2007 Consumer Germany
Primary
Concomitant
Stomatitis Hospitalization 7/23/2007 82 Male 8/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Life Threatening 8/1/2007 Female 117 lb 8/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 163 lb 8/29/2007 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 3/2/2007 Male 148 lb 8/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/5/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/1/2007 Female 117 lb 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Appendicitis Perforated Hospitalization 8/5/2007 Male 9/13/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 9/14/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/23/2007 82 Male 9/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/24/2006 72 Female 9/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 20 Male 9/24/2007 Israel
Primary
Secondary
Concomitant
Bone Marrow Failure Life Threatening 8/1/2007 Female 117 lb 10/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/2/2006 Female 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/2/2005 Male 210 lb 10/5/2007 Consumer Switzerland
Primary
Secondary
Stomatitis Hospitalization 7/22/2007 Female 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/23/2007 82 Male 10/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 10/18/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 10/15/2007 47 Female 11/2/2007 Other Health Professional United States
Primary
Secondary
Atrial Fibrillation Life Threatening 10/2/2007 11/13/2007 Physician United Kingdom
Primary
Secondary
Ventricular Tachycardia Life Threatening 8/16/2007 42 Female 153 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 10/1/2007 11/21/2007 Physician Germany
Primary
Secondary
Somnolence Hospitalization 8/18/2007 Male 11/21/2007 Physician United Kingdom
Primary
Concomitant
Thrombosis Death 4/27/2005 Male 379 lb 11/29/2007 Consumer United Kingdom
Primary
Secondary
Renal Failure Life Threatening 10/1/2007 Male 150 lb 11/29/2007 Consumer United States
Primary
Secondary
Ventricular Fibrillation Death 1/19/2005 Male 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 11/21/2007 Male 209 lb 12/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 11/30/2007 Male 198 lb 12/7/2007 Physician Sweden
Primary
Secondary
Urinary Tract Infection Hospitalization 11/4/2007 50 Female 170 lb 11/30/2007 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/4/2007 50 Female 170 lb 12/10/2007 United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 11/21/2007 Male 209 lb 12/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 11/30/2007 Male 198 lb 12/26/2007 Physician Sweden
Primary
Secondary
Myocardial Infarction Hospitalization 11/29/2007 Male 1/7/2008 Physician Sweden
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2003 62 Male 1/8/2008 Germany
Primary
Secondary
Pulmonary Oedema Hospitalization 2/16/2007 56 Female 2/13/2008 Physician Australia
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious Male 2/9/2008 Other Health Professional Germany
Primary
Secondary
Pyrexia Hospitalization 7/26/2007 Male 187 lb 2/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Ileus Life Threatening 9/18/2007 Female 160 lb 3/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2006 Female 3/7/2008 United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/1/2006 Male 3/15/2008 Physician United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/29/2008 Male 185 lb 3/17/2008 Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 3/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 3/23/2006 Male 3/19/2008 Physician United States
Primary
Secondary
Portal Hypertension Other Serious 81 Female 3/19/2008 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 3/20/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Male 163 lb 3/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 5/1/2007 Male 3/26/2008 Other Health Professional France
Primary
Concomitant
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/29/2008 Male 185 lb 3/27/2008 Physician Germany
Primary
Secondary
Concomitant
Ileus Life Threatening 9/17/2007 Female 160 lb 3/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/29/2008 Male 185 lb 3/31/2008 Consumer United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 3/19/2008 Male 157 lb 4/2/2008 Physician United Kingdom
Primary
Secondary
Hepatic Steatosis Hospitalization 5/1/2007 Male 4/4/2008 Other Health Professional France
Primary
Concomitant
Thrombosis Hospitalization 9/13/2007 Female 179 lb 4/9/2008 Physician Germany
Primary
Secondary
Concomitant
Portal Hypertension Other Serious 81 Female 4/11/2008 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 3/19/2008 Male 157 lb 4/16/2008 Physician United Kingdom
Primary
Secondary
Somnolence Hospitalization 8/18/2007 Male 123 lb 4/23/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/23/2008 Male 150 lb 4/24/2008 Physician Germany
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 11/3/2005 Male 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/9/2006 Female 5/6/2008 Physician United States
Primary
Secondary
Paraesthesia Hospitalization 11/21/2007 Male 209 lb 5/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ileus Life Threatening 9/17/2007 Female 160 lb 5/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 7/30/2007 Male 181 lb 5/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 6/4/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/28/2008 Male 236 lb 6/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/1/2006 Male 140 lb 6/10/2008 Consumer United States
Primary
Secondary
Concomitant
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 7/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Necrosis Hospitalization 5/21/2008 Female 7/14/2008 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Anastomotic Leak Other Serious 59 Male 7/17/2008 Physician Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2008 Male 172 lb 7/23/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 7/29/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/28/2008 Male 236 lb 7/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/23/2007 Male 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/21/2007 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Necrosis Hospitalization 5/21/2008 Female 8/14/2008 Physician United Kingdom
Primary
Concomitant
Mucosal Inflammation Hospitalization 7/11/2008 8/15/2008 Physician United Kingdom
Primary
Secondary
Myocardial Infarction Hospitalization 11/30/2007 Male 198 lb 8/21/2008 Physician Sweden
Primary
Secondary
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 10/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/25/2008 Male 11/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/5/2008 Male 11/7/2008 Physician Germany
Primary
Secondary
Diarrhoea Hospitalization 9/29/2008 68 Male 11/7/2008 Consumer Germany
Primary
Secondary
Neoplasm Progression Death 9/1/2008 Female 11/7/2008 Physician United Kingdom
Primary
Concomitant
Skin Discolouration Other Serious 10/14/2008 Female 11/12/2008 Physician United Kingdom
Primary
Concomitant
Keratoconjunctivitis Sicca Hospitalization 9/10/2008 Male 11/12/2008 Physician Switzerland
Primary
Secondary
Thrombocytopenia Hospitalization 9/16/2008 Female 11/13/2008 Italy
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/16/2008 Female 11/14/2008 Italy
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/23/2008 11/18/2008 Consumer United Kingdom
Primary
Secondary
Myocardial Infarction Other Serious Female 11/21/2008 Physician United Kingdom
Primary
Concomitant
Anaemia Death 9/16/2008 Female 11/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 9/29/2008 Male 11/26/2008 Physician Switzerland
Primary
Secondary
Keratoconjunctivitis Sicca Hospitalization 9/10/2008 Male 12/2/2008 Physician Switzerland
Primary
Secondary
Renal Failure Acute Other Serious 10/5/2008 Female 12/2/2008 Physician Switzerland
Primary
Secondary
Death Death 12/16/2005 Male 12/3/2008 Other Health Professional Spain
Primary
Secondary
Death Death Male 12/5/2008 Physician United Kingdom
Primary
Concomitant
Death Death 12/16/2005 Male 119 lb 12/5/2008 Consumer United Kingdom
Primary
Secondary
Death Death Female 12/5/2008 Consumer United Kingdom
Primary
Concomitant
Disease Progression Other Serious 12/3/2008 Male 170 lb 12/11/2008 Physician Italy
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/29/2008 12/15/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 12/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/4/2008 12/18/2008 Physician United Kingdom
Primary
Secondary
Cerebral Ischaemia Hospitalization 12/3/2008 Male 170 lb 12/19/2008 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/7/2007 Male 144 lb 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 11/5/2008 Female 12/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Necrosis Other Serious 5/21/2008 Female 1/8/2009 Physician United Kingdom
Primary
Concomitant
Procedural Pain Required Intervention 59 Male 1/16/2009 Physician Canada
Primary
Concomitant
Sepsis Life Threatening 7/23/2007 Male 1/27/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Cancer Recurrent Hospitalization 1/1/2008 Female 1/27/2009 Physician Germany
Primary
Secondary
Myocardial Infarction Other Serious 1/23/2008 Male 214 lb 2/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Subileus Hospitalization 1/23/2009 Female 136 lb 2/12/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/16/2008 2/18/2009 Physician Italy
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 55 Male 2/27/2009 Other Health Professional United Kingdom
Primary
Secondary

Drug Data