Bevacizumab combined with Erlotinib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Diarrhoea Death 12/30/2005 66 Male 174 lb 1/27/2006 Physician France
Primary
Secondary
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 1/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/7/2006 38 Female 255 lb 2/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2005 56 Female 166 lb 1/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 2/17/2006 46 Female 129 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/17/2005 73 Male 141 lb 3/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Life Threatening 8/19/2006 74 Male 10/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Life Threatening 8/19/2005 74 Male 11/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Penile Pain Hospitalization 3/18/2007 Male 182 lb 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Subileus Hospitalization 12/11/2006 Male 4/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Penile Pain Hospitalization 3/18/2007 Male 182 lb 4/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 12/20/2006 Female 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheitis Hospitalization 1/31/2007 Male 145 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Performance Status Decreased Hospitalization 2/13/2007 59 Male 4/18/2007 Other Health Professional United States
Primary
Secondary
Tracheal Injury Death 2/13/2007 Male 145 lb 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 1/13/2007 Male 172 lb 4/20/2007 United States
Primary
Secondary
Concomitant
Death Hospitalization 3/16/2007 54 Male 4/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 2/12/2007 64 Male 190 lb 4/23/2007 Consumer United States
Primary
Secondary
Transaminases Increased Hospitalization 4/12/2007 63 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Oedema Hospitalization 4/21/2007 Male 4/30/2007 Consumer United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Acquired Haemophilia With Anti Fviii, Xi, Or Xiii Hospitalization 8/17/2006 76 Male 5/2/2007 Physician United Kingdom
Primary
Secondary
Acquired Haemophilia With Anti Fviii, Xi, Or Xiii Hospitalization 8/17/2006 76 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Fatigue Hospitalization 12/20/2006 Female 5/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 4/1/2007 51 Male 168 lb 5/15/2007 Consumer United States
Primary
Secondary
Vomiting Death 4/1/2007 Male 5/16/2007 Physician United Kingdom
Primary
Secondary
Renal Colic Hospitalization 5/2/2007 Male 143 lb 5/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 4/12/2007 Male 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Tamponade Hospitalization 4/25/2007 Female 150 lb 5/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/14/2007 Female 158 lb 5/17/2007 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 5/13/2007 Male 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/16/2007 81 Male 181 lb 5/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 5/11/2007 67 Female 97 lb 5/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 5/13/2007 Male 5/23/2007 Physician United States
Primary
Secondary
Concomitant
Infection Hospitalization 3/3/2007 53 Male 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/11/2007 67 Female 97 lb 5/25/2007 Physician United States
Primary
Secondary
Concomitant
Oedema Hospitalization 4/21/2007 Male 6/4/2007 Consumer United States
Primary
Secondary
Concomitant
Tracheal Injury Death 2/13/2007 Male 145 lb 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 5/27/2007 42 Female 6/6/2007 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 5/14/2007 Female 158 lb 6/7/2007 Physician United States
Primary
Secondary
Periodontal Disease Other Serious 3/2/2006 72 Male 159 lb 6/15/2007 Consumer United States
Primary
Secondary
Oesophagitis Hospitalization 5/27/2007 42 Female 6/15/2007 Other Health Professional United States
Primary
Secondary
Death Death Male 204 lb 6/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Tumour Excision Death Male 204 lb 6/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 7/3/2007 Physician United States
Primary
Secondary
Concomitant
Body Temperature Increased Hospitalization 3/8/2006 Female 150 lb 7/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Colic Hospitalization 5/2/2007 Male 143 lb 7/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Bronchopleural Fistula Other Serious 76 Male 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 7/4/2007 Male 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Neoplasm Progression Death 7/4/2007 Male 7/23/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Body Temperature Increased Hospitalization 3/8/2006 Female 150 lb 7/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/15/2007 Female 158 lb 7/30/2007 Physician United States
Primary
Secondary
Skin Ulcer Other Serious 4/30/2007 Male 8/6/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 6/1/2007 70 Female 8/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Oedema Peripheral Hospitalization 8/1/2007 Male 8/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 8/6/2007 52 Male 170 lb 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 2/17/2006 Male 196 lb 8/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angioedema Other Serious 8/5/2007 Female 209 lb 8/15/2007 Physician United States
Primary
Secondary
Hydropneumothorax Hospitalization 9/5/2006 Male 8/15/2007 Pharmacist United Kingdom
Primary
Secondary
Oedema Peripheral Hospitalization 8/1/2007 Male 8/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/8/2007 Male 142 lb 8/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Food Allergy Disability 8/5/2007 Female 209 lb 8/24/2007 Physician United States
Primary
Secondary
Tracheal Injury Death 2/13/2007 Male 145 lb 8/28/2007 Physician United States
Primary
Secondary
Concomitant
Superinfection Hospitalization 8/17/2007 Male 8/31/2007 Physician United Kingdom
Primary
Secondary
Pancreatic Carcinoma Metastatic Death 8/6/2007 52 Male 170 lb 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Gallbladder Perforation Hospitalization 8/16/2007 Male 8/31/2007 Consumer Denmark
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death Male 204 lb 9/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/8/2007 Male 142 lb 9/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization 9/5/2006 Male 9/6/2007 Pharmacist United Kingdom
Primary
Secondary
Perirectal Abscess Hospitalization 12/7/2006 Male 134 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Hospitalization 2/20/2007 Male 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Enterovesical Fistula Hospitalization 2/26/2007 Male 190 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 8/1/2007 Male 9/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 8/31/2007 67 Male 9/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/3/2007 Female 113 lb 9/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Obstruction Gastric Hospitalization 7/18/2007 67 Male 134 lb 9/10/2007 United States
Primary
Secondary
Concomitant
Sudden Death Death 2/17/2006 Male 196 lb 9/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophageal Carcinoma Death Male 204 lb 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/11/2007 Male 179 lb 9/18/2007 Physician United States
Primary
Secondary
Gallbladder Perforation Hospitalization 8/16/2007 Male 9/19/2007 Consumer Denmark
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 3/8/2006 Female 150 lb 9/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Bursitis Hospitalization 8/17/2007 Male 9/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 4/12/2007 Male 9/20/2007 Physician United States
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 12/7/2006 Male 134 lb 9/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 5/27/2007 42 Female 9/24/2007 Other Health Professional United States
Primary
Secondary
Death Death 9/10/2007 Male 9/27/2007 Consumer United Kingdom
Primary
Secondary
Sudden Death Death 2/17/2006 Male 196 lb 9/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 8/31/2007 67 Male 9/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Perianal Abscess Hospitalization 8/9/2007 56 Male 9/27/2007 Consumer United States
Primary
Secondary
Concomitant
Death Death 9/3/2007 Female 113 lb 9/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Disorder Death 9/10/2007 Male 10/2/2007 Consumer United Kingdom
Primary
Secondary
Somnolence Hospitalization 1/18/2006 70 Female 9/28/2007 Physician Belgium
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 4/12/2007 Male 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 2/17/2006 Male 196 lb 10/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Life Threatening 9/28/2007 Female 102 lb 10/9/2007 Physician United States
Primary
Secondary
Death Death 10/1/2007 Male 167 lb 10/10/2007 Other Health Professional United States
Primary
Secondary
Perianal Abscess Hospitalization 8/9/2007 56 Male 10/12/2007 Consumer United States
Primary
Secondary
Concomitant
Death Death 10/1/2007 Male 167 lb 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Life Threatening 9/28/2007 Female 102 lb 10/19/2007 Physician United States
Primary
Secondary
Death Death 9/10/2007 Male 10/23/2007 Consumer United Kingdom
Primary
Secondary
Hypertension Hospitalization 10/23/2007 78 Male 10/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/14/2007 Male 218 lb 10/29/2007 Physician United States
Primary
Secondary
Hand Deformity Other Serious 10/14/2007 Male 7 lb 11/2/2007 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 10/24/2007 Male 130 lb 11/5/2007 Physician United States
Primary
Secondary
Death Hospitalization 9/3/2007 Female 113 lb 11/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Limb Reduction Defect Other Serious 10/14/2007 Male 7 lb 11/7/2007 Other Health Professional United States
Primary
Secondary
Transmission Of Drug Via Semen Other Serious 10/14/2007 Male 7 lb 10/31/2007 Physician United States
Primary
Secondary
Rectal Haemorrhage Hospitalization 10/17/2007 Male 84 lb 11/1/2007 Other Health Professional United States
Primary
Secondary
Pulmonary Haemorrhage Life Threatening 9/28/2007 Female 102 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/8/2007 Female 11/13/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Enterovesical Fistula Hospitalization 2/26/2007 Male 190 lb 11/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/5/2007 Male 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Hospitalization 9/3/2007 Female 113 lb 11/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 10/24/2007 Male 130 lb 11/14/2007 Physician United States
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 12/7/2006 Male 134 lb 11/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/6/2007 Female 117 lb 11/16/2007 Physician United States
Primary
Secondary
Hypertension Hospitalization 10/23/2007 78 Male 11/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 10/1/2007 Male 167 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiogenic Shock Hospitalization 11/6/2007 Female 117 lb 11/27/2007 Physician United States
Primary
Secondary
Convulsion Hospitalization 10/6/2007 Male 11/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 10/28/2007 63 Male 11/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 11/18/2007 Female 12/3/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 10/1/2007 Male 167 lb 12/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 10/23/2007 78 Male 12/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumomediastinum Hospitalization 12/3/2007 Male 12/21/2007 Physician United Kingdom
Primary
Secondary
Dysphagia Hospitalization 10/29/2007 Male 147 lb 12/21/2007 Physician United States
Primary
Secondary
Hyperglycaemia Hospitalization 11/18/2007 Female 12/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/11/2007 Female 12/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/10/2007 Male 126 lb 12/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumomediastinum Hospitalization 12/3/2007 Male 12/31/2007 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 10/1/2006 Female 12/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 11/18/2007 Female 1/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/10/2007 Male 126 lb 1/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 12/7/2006 Male 134 lb 1/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Enterovesical Fistula Hospitalization 2/26/2007 Male 190 lb 1/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Fistula Hospitalization 2/20/2007 Male 1/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 10/24/2007 Male 130 lb 1/11/2008 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 11/18/2007 Female 1/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 11/12/2007 Male 1/17/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/22/2007 Male 156 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/12/2007 Female 1/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/19/2007 Female 1/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 12/10/2007 52 Male 1/23/2008 Physician United Kingdom
Primary
Secondary
Sepsis Hospitalization 10/22/2007 Male 156 lb 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 11/18/2007 Female 1/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 1/13/2008 Male 193 lb 1/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/12/2006 Female 2/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/12/2006 Female 2/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Death 11/14/2007 Male 2/4/2008 Physician United Kingdom
Primary
Secondary
Cardiac Arrest Death 8/8/2007 65 Male 154 lb 2/5/2008 Physician United States
Primary
Secondary

Drug Data