Bevacizumab combined with Erlotinib Hydrochloride

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 6/23/2006 76 Male 172 lb 2/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/12/2007 76 Male 172 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/8/2007 71 Male 177 lb 3/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/4/2007 71 Male 177 lb 3/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 6/26/2009 8/24/2009 Physician Denmark
Primary
Secondary
Infected Skin Ulcer Hospitalization 6/15/2009 9/4/2009 Consumer Denmark
Primary
Secondary
Skin Ulcer Hospitalization 6/15/2009 9/25/2009 Physician Denmark
Primary
Secondary
Skin Necrosis Hospitalization 6/15/2009 10/16/2009 Other Health Professional Denmark
Primary
Secondary
Skin Ulcer Hospitalization 10/2/2008 49 Female 10/30/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/12/2009 49 Female 11/10/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/23/2009 NotSpecified 11/6/2009 Physician Sweden
Primary
Secondary
Pancreatic Carcinoma Hospitalization 7/27/2009 65 Male 11/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 9/23/2009 12/4/2009 Physician Sweden
Primary
Secondary
Death Death 8/1/2009 2/5/2010 Physician United States
Primary
Secondary
Pyrexia Hospitalization 2/8/2010 74 Male 3/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Abscess Hospitalization 12/27/2009 68 Female 3/12/2010 Physician United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 3/12/2010 Other Health Professional United States
Primary
Secondary
Pancytopenia Hospitalization 12/10/2009 52 Female 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 3/4/2010 52 Male 4/9/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/11/2009 47 Female 112 lb 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 5/1/2008 56 Male 161 lb 4/28/2010 Physician Canada
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 5/1/2008 56 Male 5/3/2010 Physician Canada
Primary
Secondary
Concomitant
Disease Progression Death Male 113 lb 5/10/2010 Other Health Professional United States
Primary
Secondary
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 212 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 4/19/2010 51 Male 238 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 5/1/2008 56 Male 5/4/2010 Physician Canada
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death Male 113 lb 5/14/2010 Other Health Professional United States
Primary
Secondary
Pancreatitis Hospitalization 4/8/2010 34 Female 204 lb 5/21/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/7/2010 73 Male 126 lb 5/21/2010 Physician United States
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious NotSpecified 6/11/2010 Physician United States
Primary
Secondary
Pulmonary Embolism Other Serious 6/11/2010 Physician United States
Primary
Secondary
Tachycardia Hospitalization 5/27/2010 56 Male 6/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 6/11/2010 Other Health Professional United States
Primary
Secondary
Urinary Tract Infection Hospitalization 5/18/2010 55 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/13/2008 56 Female 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 12/11/2009 47 Female 112 lb 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 12/11/2009 47 Female 7/8/2010 Other Health Professional United States
Primary
Secondary
Rash Hospitalization 6/13/2010 92 Female 7/9/2010 Other Health Professional United States
Primary
Secondary
Urinary Tract Infection Hospitalization 5/18/2010 55 Female 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/27/2010 56 Male 7/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Circulatory Collapse Death 3/23/2009 52 Male 7/19/2010 Physician Hong Kong
Primary
Secondary
Hypertensive Encephalopathy Hospitalization 1/20/2010 61 Male 185 lb 8/9/2010 Physician France
Primary
Secondary
Concomitant
Hypertensive Encephalopathy Hospitalization 1/20/2010 61 Male 185 lb 8/9/2010 Physician France
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 12/1/2009 47 Female 247 lb 8/11/2010 Other Health Professional United States
Primary
Secondary
Blindness Hospitalization 10/3/2008 70 Male 112 lb 8/16/2010 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 12/11/2009 47 Female 8/10/2010 Other Health Professional United States
Primary
Secondary
Death Death 3/23/2009 52 Male 8/18/2010 Physician United States
Primary
Secondary
Transaminases Increased Other Serious 12/1/2009 47 Female 8/18/2010 Physician United States
Primary
Secondary
Transaminases Increased Other Serious 12/1/2009 47 Female 247 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 11/1/2007 64 Female 161 lb 9/1/2010 Lawyer United States
Primary
Concomitant
Death Death 3/23/2009 52 Male 8/25/2010 Other Health Professional Hong Kong
Primary
Secondary
Pulmonary Oedema Other Serious 12/1/2009 47 Female 9/1/2010 Physician United States
Primary
Secondary
Haemoptysis Hospitalization 4/21/2008 64 Female 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/8/2010 33 Female 204 lb 9/17/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/7/2008 73 Male 198 lb 9/20/2010 Physician Spain
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/12/2010 83 Male 146 lb 9/20/2010 Physician United States
Primary
Secondary
Pleural Effusion Hospitalization 8/9/2010 77 Female 9/16/2010 Other Health Professional United States
Primary
Secondary
Wound Dehiscence Other Serious 83 Male 182 lb 9/24/2010 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 5/7/2008 73 Male 198 lb 9/27/2010 Physician Spain
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/12/2010 83 Male 9/28/2010 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 8/8/2010 49 Male 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 1/16/2007 67 Male 194 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Staphylococcal Sepsis Hospitalization 6/28/2007 85 Female 184 lb 11/1/2010 Other Health Professional Colombia
Primary
Secondary
Weight Increased Hospitalization 7/4/2010 60 Male 142 lb 11/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 64 Female 161 lb 11/22/2010 Lawyer United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 10/4/2010 75 Male 11/11/2010 Physician United States
Primary
Secondary
Concomitant
Syndactyly Congenital Anomaly 10/14/2007 Male 7 lb 12/14/2010 Physician United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 8/6/2009 60 Male 2/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 8/6/2009 60 Male 2/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chest Pain Life Threatening 12/15/2010 64 Male 2/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 8/6/2009 60 Male 3/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 49 Male 4/14/2011 Physician United States
Primary
Concomitant
Glioblastoma Multiforme Other Serious 2/18/2011 17 Female 5/5/2011 Physician United States
Primary
Secondary
Pneumonia Staphylococcal Hospitalization 4/22/2011 71 Female 5/6/2011 Physician United Kingdom
Primary
Secondary
Protein Total Decreased Other Serious 2/18/2011 17 Female 5/10/2011 Physician United States
Primary
Secondary
Pleural Effusion Hospitalization 53 Female 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 4/28/2011 71 Female 5/16/2011 Physician United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 12/11/2009 47 Female 112 lb 5/26/2011 Physician United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization Female 188 lb 6/9/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 9/23/2009 62 Male 152 lb 6/10/2011 Physician Germany
Primary
Secondary
Dyspnoea Hospitalization 9/23/2009 62 Male 6/13/2011 Physician Germany
Primary
Secondary
Abdominal Pain Hospitalization 4/3/2008 59 Female 110 lb 6/16/2011 Other Health Professional United States
Primary
Secondary
Left Ventricular Dysfunction Other Serious 1/3/2011 57 Female 93 lb 6/16/2011 Physician United States
Primary
Secondary
Drug Interaction Hospitalization 47 Male 207 lb 6/16/2011 Pharmacist United States
Primary
Concomitant
Interacting
Dyspnoea Hospitalization 9/23/2009 62 Male 152 lb 6/17/2011 Physician Germany
Primary
Secondary
Chills Life Threatening 1/16/2007 67 Male 194 lb 6/21/2011 Physician United States
Primary
Secondary
Death Death 4/3/2008 59 Female 110 lb 6/21/2011 Other Health Professional United States
Primary
Secondary
General Physical Health Deterioration Required Intervention 6/7/2011 72 Male 144 lb 6/20/2011 Other Health Professional United States
Primary
Secondary
Dyspnoea Hospitalization 9/23/2009 62 Male 6/21/2011 Physician Germany
Primary
Secondary
Drug Interaction Other Serious 47 Male 249 lb 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Interacting
Malignant Pleural Effusion Hospitalization 9/23/2009 62 Male 152 lb 6/28/2011 Physician Germany
Primary
Secondary
Swelling Other Serious 47 Male 6/29/2011 Other Health Professional United Kingdom
Primary
Interacting
Embolism Arterial Other Serious 1/3/2011 57 Female 93 lb 6/30/2011 Physician United States
Primary
Secondary
Swelling Other Serious 47 Male 6/30/2011 Physician United Kingdom
Primary
Interacting
Drug Interaction Other Serious 47 Male 249 lb 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Interacting
Diarrhoea Other Serious 47 Male 249 lb 7/5/2011 Consumer United Kingdom
Primary
Secondary
International Normalised Ratio Increased Other Serious 47 Male 249 lb 7/8/2011 Other Health Professional United States
Primary
Secondary
Diarrhoea Other Serious 47 Male 249 lb 7/12/2011 Physician United States
Primary
Secondary
Rash Other Serious 47 Male 249 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Contusion Other Serious 47 Male 249 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rash Other Serious 47 Male 249 lb 8/5/2011 Other Health Professional United Kingdom
Primary
Interacting
Cardiac Failure Acute Hospitalization 4/5/2011 57 Female 8/5/2011 Physician United States
Primary
Secondary
Tetany Hospitalization 8/17/2011 India
Primary
Secondary
Cardiac Failure Acute Hospitalization 5/10/2011 57 Female 8/22/2011 Physician United States
Primary
Secondary
Retinal Detachment Other Serious 8/26/2011 71 Female 168 lb 9/6/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/4/2011 58 Male 9/19/2011 Physician France
Primary
Secondary
Concomitant
Fall Hospitalization 9/17/2011 79 Female 83 lb 11/8/2011 Other Health Professional United States
Primary
Concomitant
Pneumothorax Hospitalization 10/28/2011 73 Female 106 lb 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 11/11/2011 Consumer United States
Primary
Secondary
Concomitant
Arthropathy Hospitalization 9/1/2011 79 Female 84 lb 11/16/2011 Physician United States
Primary
Secondary
Pneumothorax Hospitalization 10/28/2011 73 Female 106 lb 11/16/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11/11/2011 72 Male 265 lb 11/11/2011 United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death Female 11/22/2011 Physician United States
Primary
Concomitant
Off Label Use Death 11/11/2011 Male 265 lb 11/28/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 11/11/2011 72 Male 225 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 10/31/2011 59 Female 12/9/2011 Physician United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 10/9/2011 70 Male 12/12/2011 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 12/7/2011 71 Female 86 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/13/2011 60 Male 251 lb 1/3/2012 Physician United States
Primary
Secondary
Concomitant
Off Label Use Death 1/13/2012 Other Health Professional Sweden
Primary
Secondary
Cholecystitis Acute Hospitalization 12/1/2011 Male 1/18/2012 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 12/1/2011 Male 1/20/2012 Physician United States
Primary
Secondary
Nausea Hospitalization 12/27/2011 49 Female 176 lb 2/7/2012 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/27/2012 68 Female 176 lb 2/15/2012 Physician United States
Primary
Secondary
Concomitant
Colonic Polyp Hospitalization 12/13/2011 60 Male 251 lb 2/16/2012 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 2/20/2012 Other Health Professional Switzerland
Primary
Secondary
Cardiac Failure Death 2/20/2012 Other Health Professional Switzerland
Primary
Secondary
Haemoptysis Death 2/20/2012 Other Health Professional Switzerland
Primary
Secondary
Hypertension Other Serious 2/22/2012 Other Health Professional United States
Primary
Secondary
Haemorrhage Other Serious 2/22/2012 Other Health Professional United States
Primary
Secondary
Incision Site Pain Hospitalization 1/26/2012 47 Male 231 lb 2/22/2012 Physician United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 2/22/2012 Other Health Professional United States
Primary
Secondary
Blood Bilirubin Increased Other Serious 12/13/2011 60 Male 251 lb 2/24/2012 Physician United States
Primary
Secondary
Concomitant
Hypertension Other Serious 3/7/2012 Other Health Professional United States
Primary
Secondary
Bronchitis Other Serious 12/24/2011 47 Male 231 lb 3/14/2012 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 47 Male 249 lb 3/26/2012 Other Health Professional United States
Primary
Secondary
Interacting
Hypertension Other Serious 1/16/2012 Male 3/28/2012 Consumer United States
Primary
Secondary
Epistaxis Other Serious 54 Female 3/30/2012 Taiwan, Province Of China
Primary
Secondary
Diarrhoea Other Serious 3/31/2012 67 Male 185 lb 4/16/2012 Physician Germany
Primary
Secondary
Concomitant
Off Label Use Hospitalization 3/1/2012 80 Male 185 lb 4/19/2012 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 53 Male 4/20/2012 Other Health Professional Netherlands
Primary
Secondary
Convulsion Hospitalization 3/21/2012 61 Male 130 lb 5/3/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 47 Female 4/30/2012 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 10/31/2011 59 Female 119 lb 5/7/2012 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 4/11/2012 58 Female 139 lb 5/9/2012 Physician Germany
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 12/7/2011 71 Female 86 lb 5/11/2012 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 4/2/2012 80 Male 2 lb 4/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 3/1/2012 80 Male 185 lb 5/17/2012 Physician United States
Primary
Secondary
Concomitant
Haematoma Hospitalization 56 Female 5/18/2012 Other Health Professional United States
Primary
Secondary
Subileus Hospitalization 5/8/2012 5/24/2012 Physician Sweden
Primary
Secondary