Bevacizumab combined with Doxorubicin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/1/2005 55 Female 132 lb 2/9/2006 Physician Canada
Primary
Secondary
Concomitant
Myalgia Other Serious 1/10/2007 43 Female 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 2/28/2007 Female 4/19/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/3/2007 53 Female 148 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Radiation Skin Injury Other Serious 5/1/2007 42 Female 12/11/2008 Physician United States
Primary
Concomitant
Lacrimation Increased Other Serious 10/18/2006 12/11/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 3/6/2009 Female 4/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Arthralgia Disability 12/1/2008 Female 4/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/15/2008 78 Female 159 lb 4/16/2009 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 5/15/2009 Female 12/2/2009 Physician United Kingdom
Primary
Secondary
Oesophagitis Hospitalization 2/5/2010 Female 114 lb 2/23/2010 Physician United States
Primary
Secondary
Tumour Necrosis Hospitalization 3/4/2010 Male 64 lb 3/18/2010 Physician France
Primary
Secondary
Vomiting Life Threatening 2/9/2010 Female 143 lb 3/22/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/19/2009 Female 139 lb 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Hospitalization 6/9/2010 41 Female 154 lb 6/28/2010 Physician Canada
Primary
Secondary
Concomitant
Implant Site Necrosis Other Serious 6/11/2010 66 Female 134 lb 7/1/2010 Physician France
Primary
Secondary
Implant Site Necrosis Other Serious 6/11/2010 66 Female 134 lb 7/2/2010 Physician France
Primary
Secondary
Peripheral Sensorimotor Neuropathy Other Serious 8/31/2010 9 Male 77 lb 10/12/2010 Physician France
Primary
Secondary
Concomitant
Peripheral Sensorimotor Neuropathy Other Serious 8/31/2010 9 Male 71 lb 11/24/2010 Physician France
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/6/2010 58 Female 12/20/2010 Physician United States
Primary
Secondary
Shock Other Serious 10/6/2010 58 Female 12/28/2010 Physician United States
Primary
Secondary
Neuralgia Other Serious 8/31/2010 9 Male 69 lb 1/4/2011 Other Health Professional France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 12/23/2010 9 Male 41 lb 1/10/2011 Physician France
Primary
Secondary
Concomitant
Post Procedural Haematoma Hospitalization 12/14/2010 7 Male 66 lb 1/18/2011 Physician France
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 10/21/2010 20 Female 1/24/2011 Physician United States
Primary
Secondary
Febrile Bone Marrow Aplasia Other Serious 8/31/2010 9 Male 77 lb 2/21/2011 Physician France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 12/23/2010 9 Male 42 lb 3/4/2011 Physician France
Primary
Secondary
Concomitant
Staphylococcal Skin Infection Other Serious 10/3/2003 46 Female 128 lb 3/9/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Viral Death 3/14/2011 Physician United States
Primary
Secondary
Shock Death 10/6/2010 58 Female 142 lb 3/17/2011 Other Health Professional United States
Primary
Secondary
Renal Tubular Disorder Hospitalization 12/14/2010 7 Male 66 lb 3/31/2011 Physician France
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/21/2010 20 Female 4/1/2011 Consumer United States
Primary
Secondary
Hypercalcaemia Hospitalization 10/3/2003 46 Female 128 lb 4/5/2011 United States
Primary
Concomitant
Post Procedural Haematoma Hospitalization 12/14/2010 7 Male 66 lb 4/11/2011 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 8/31/2010 9 Male 77 lb 4/12/2011 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/7/2010 9 Male 42 lb 4/14/2011 Physician France
Primary
Secondary
Concomitant
Implant Site Necrosis Other Serious 6/11/2010 66 Female 132 lb 4/22/2011 Physician France
Primary
Secondary
Mucosal Inflammation Hospitalization 4/3/2010 7 Male 52 lb 4/22/2011 Physician France
Primary
Secondary
Concomitant
Peripheral Sensorimotor Neuropathy Other Serious 8/31/2010 9 Male 69 lb 4/28/2011 Other Health Professional France
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 57 Female 5/3/2011 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Life Threatening 4/17/2011 38 Female 190 lb 5/3/2011 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Death 2006 Female 9/11/2012 Consumer Us
Primary
Concomitant
Urogenital Fistula Other Serious 11/16/2012 Other Health Professional Country Not Specified
Primary
Secondary
Mucosal Inflammation Hospitalization 11/7/2010 10 Male 41 lb 6/26/2013 Physician Fr
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/27/2010 55 NotSpecified 141 lb 2/14/2013 Other Health Professional Gb
Primary
Concomitant
Syncope Hospitalization 10/3/2010 46 10/23/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/19/2012 Country Not Specified
Primary
Secondary
Pulmonary Embolism Other Serious 9/19/2012 Country Not Specified
Primary
Secondary
Deep Vein Thrombosis Other Serious 9/20/2012 Country Not Specified
Primary
Secondary
Deep Vein Thrombosis Other Serious 9/19/2012 Country Not Specified
Primary
Secondary
Mucosal Inflammation Hospitalization 7/15/2011 3 Female 29 lb 12/12/2012 Physician Gb
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 3/18/2010 13 Male 119 lb 6/24/2013 Physician Nl
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/17/2011 47 Female 220 lb 5/8/2013 Physician De
Primary
Secondary
Left Ventricular Dysfunction Other Serious 4/28/2009 37 Female 12/23/2012 Physician Us
Primary
Concomitant
Ingrowing Nail Hospitalization 10/7/2011 17 Male 108 lb 9/4/2012 Country Not Specified
Primary
Secondary
Concomitant
Malnutrition Disability 2/17/2012 17 Female 100 lb 6/5/2013 Physician Fr
Primary
Secondary
Febrile Neutropenia Hospitalization 1/9/2012 9 Female 54 lb 10/16/2012 Country Not Specified
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/11/2008 37 Female 125 lb 1/4/2013 Physician Us
Primary
Secondary
Dyspnoea Hospitalization 7/9/2012 61 Female 157 lb 8/28/2012 Physician Us
Primary
Secondary
General Physical Health Deterioration Hospitalization 5/9/2012 50 Female 174 lb 9/3/2012 Consumer De
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 22 Female 9/10/2012 Physician Us
Primary
Secondary
Left Ventricular Dysfunction Other Serious 59 Male 9/27/2012 Physician Us
Primary
Secondary
Left Ventricular Dysfunction Other Serious 63 Female 9/28/2012 Physician Us
Primary
Secondary
Left Ventricular Dysfunction Other Serious 81 Male 9/28/2012 Physician Us
Primary
Secondary
Troponin Increased Other Serious 69 Female 9/28/2012 Physician Us
Primary
Secondary
Oropharyngeal Pain Hospitalization 9/15/2012 Female 172 lb 10/8/2012 Physician At
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 8/23/2010 54 Female 205 lb 10/11/2012 Physician Us
Primary
Secondary
Impaired Healing Other Serious Female 10/12/2012 Other Health Professional Us
Primary
Secondary
Renal Failure Acute Hospitalization 8/29/2012 51 Female 10/24/2012 Physician Us
Primary
Secondary
Hypercholesterolaemia Other Serious 10/25/2012 Physician Us
Primary
Secondary
General Physical Health Deterioration Hospitalization 10/18/2012 33 Female 82 lb 11/1/2012 Physician De
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 10/1/2012 71 Female 159 lb 8/22/2013 Physician De
Primary
Secondary
Anal Fissure Hospitalization 10/8/2012 7 Male 45 lb 11/7/2012 Physician Be
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 10/8/2012 7 Male 45 lb 11/16/2012 Physician Be
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 10/8/2012 7 Male 45 lb 11/16/2012 Physician Be
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/25/2010 64 Female 137 lb 11/26/2012 Physician Us
Primary
Secondary
Pain Hospitalization 10/8/2012 6 Male 45 lb 11/19/2012 Physician Be
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/17/2011 38 Female 190 lb 11/28/2012 Physician Us
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/10/2009 50 Female 142 lb 11/30/2012 Physician Us
Primary
Secondary
Concomitant
Proctalgia Hospitalization 2/16/2009 53 Female 162 lb 11/30/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Vomiting Other Serious Female 2/13/2013 Other Health Professional Us
Primary
Secondary
Pain Other Serious Female 2/13/2013 Physician Us
Primary
Secondary
Myalgia Other Serious Female 2/14/2013 Physician Us
Primary
Secondary
Mucosal Inflammation Hospitalization 8/4/2012 3 Male 32 lb 12/10/2012 Physician Pl
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/7/2010 57 Female 116 lb 12/19/2012 Physician Us
Primary
Secondary
Mucosal Inflammation Hospitalization 8/4/2012 3 Male 32 lb 1/28/2013 Physician Pl
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/24/2012 63 Female 130 lb 12/26/2012 Physician De
Primary
Secondary
Pyrexia Hospitalization 7/24/2012 63 Female 130 lb 8/20/2013 Physician De
Primary
Secondary
Proteinuria Hospitalization 12/26/2012 Physician Country Not Specified
Primary
Secondary
Pyrexia Hospitalization 3/1/2012 1 Female 29 lb 6/27/2013 Physician Es
Primary
Secondary
Pancytopenia Death 11/17/2011 64 Female 146 lb 1/2/2013 Physician De
Primary
Secondary
Concomitant
Clostridium Difficile Infection Hospitalization 11/1/2012 70 Female 89 lb 1/4/2013 Physician Us
Primary
Secondary
Peritonitis Hospitalization 3/17/2011 56 Female 179 lb 1/4/2013 Physician De
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/14/2009 64 Male 1/4/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/14/2009 64 Male 1/4/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/14/2009 64 Male 1/3/2013 Physician Gb
Primary
Secondary
Concomitant
Speech Disorder Other Serious Female 1/10/2013 Physician Us
Primary
Secondary
Diarrhoea Hospitalization 11/7/2012 55 Female 165 lb 8/27/2013 Physician De
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 10/5/2012 15 Female 104 lb 5/13/2013 Other Health Professional Cz
Primary
Secondary
Skin Exfoliation Other Serious 2/11/2011 Male 44 lb 1/18/2013 Physician Fr
Primary
Secondary
Weight Decreased Other Serious 3/12/2011 15 Female 83 lb 1/22/2013 Physician Fr
Primary
Secondary
Mucosal Inflammation Hospitalization 11/7/2010 10 Male 42 lb 4/24/2013 Physician Fr
Primary
Secondary
Concomitant
Ejection Fraction Other Serious NotSpecified 2/4/2013 Physician Au
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 12/1/2012 Female 142 lb 2/22/2013 Physician Fr
Primary
Secondary
Device Related Sepsis Death 11/24/2012 66 Female 165 lb 2/1/2013 Physician De
Primary
Secondary
Mucosal Inflammation Hospitalization 1/28/2013 13 Female 104 lb 6/26/2013 Physician Fr
Primary
Secondary
Concomitant
Myositis Hospitalization 12/30/2012 50 Female 141 lb 2/12/2013 Physician Us
Primary
Secondary
Skin Ulcer Other Serious 1/30/2013 44 Female 139 lb 2/11/2013 Physician De
Primary
Secondary
Pulmonary Embolism Other Serious NotSpecified 3/1/2013 Other Health Professional Us
Primary
Secondary
Stomatitis Hospitalization 2/17/2013 50 Female 172 lb 5/2/2013 Physician De
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious NotSpecified 5/24/2013 Other Health Professional Country Not Specified
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 65 Female 1/31/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 3/26/2013 Other Health Professional Us
Primary
Secondary
Vaginal Ulceration Other Serious 3/28/2013 44 Female 128 lb 8/14/2013 Physician De
Primary
Secondary
Paronychia Other Serious 3/19/2013 18 Female 4/9/2013 Physician Fr
Primary
Secondary
Ejection Fraction Decreased 6/15/2010 42 Female 156 lb 4/25/2013 Physician Us
Primary
Secondary
Ejection Fraction Decreased 8/3/2009 61 Female 134 lb 4/25/2013 Physician Us
Primary
Secondary
Concomitant
Ejection Fraction Decreased 9/11/2009 49 Female 194 lb 4/25/2013 Physician Us
Primary
Concomitant
Ejection Fraction Decreased 3/1/2011 53 Female 158 lb 4/25/2013 Other Health Professional Us
Primary
Concomitant
Ejection Fraction Decreased 8/5/2009 35 Female 229 lb 4/25/2013 Other Health Professional Us
Primary
Secondary
Ejection Fraction Decreased 2/23/2010 54 Female 133 lb 4/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Aortic Dissection Life Threatening 9/24/2010 68 Female 122 lb 4/26/2013 Physician Br
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious Female 5/3/2013 Other Health Professional Us
Primary
Secondary
Renal Failure Chronic Other Serious Female 5/3/2013 Other Health Professional Us
Primary
Secondary
Renal Failure Chronic Other Serious Female 5/3/2013 Other Health Professional Us
Primary
Secondary
Renal Failure Chronic Other Serious Female 5/3/2013 Other Health Professional Us
Primary
Secondary
Renal Failure Chronic Other Serious Female 5/3/2013 Other Health Professional Us
Primary
Secondary
Thrombotic Microangiopathy Other Serious 71 Female 5/3/2013 Other Health Professional Us
Primary
Secondary
Renal Failure Chronic Other Serious Female 5/3/2013 Other Health Professional Us
Primary
Secondary
Mucosal Inflammation Hospitalization 11/7/2010 10 Male 42 lb 5/6/2013 Physician Fr
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 1/3/2013 46 Female 236 lb 5/9/2013 Physician De
Primary
Secondary
Mucosal Inflammation Hospitalization 5/2/2012 69 Female 106 lb 5/10/2013 Physician De
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 5/13/2013 Other Health Professional Us
Primary
Secondary
Performance Status Decreased Other Serious 11/28/2009 10 Male 48 lb 6/14/2013 Physician Fr
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious NotSpecified 7/10/2013 Physician Gb
Primary
Secondary
Platelet Count Decreased Other Serious 7/14/2011 3 Female 6/19/2013 Physician Gb
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 59 Female 7/1/2013 Physician Fr
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious NotSpecified 7/1/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Other Serious 59 Female 7/5/2013 Physician Fr
Primary
Secondary
Neutropenic Infection Hospitalization 5/21/2013 9 Female 7/16/2013 Physician Nl
Primary
Secondary
Concomitant
Off Label Use Other Serious 7/14/2011 2 Female 7/15/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Maternal Exposure Timing Unspecified Other Serious NotSpecified 7/16/2013 Physician Us
Primary
Secondary
Exposure During Pregnancy Other Serious Female 143 lb 7/22/2013 Physician Us
Primary
Secondary
Concomitant
Cardiac Failure Other Serious Female 7/19/2013 Other Health Professional Us
Primary
Secondary
Impaired Healing Other Serious Female 8/1/2013 Other Health Professional Us
Primary
Secondary
Stomatitis Other Serious 6/20/2013 62 Female 7/26/2013 Physician Nl
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 7/30/2013 Physician Us
Primary
Secondary
Wound Other Serious 10/3/2003 47 Female 128 lb 11/7/2012 Consumer Country Not Specified
Primary
Concomitant
Wound Other Serious 10/3/2003 47 Female 128 lb 8/1/2013 Consumer Us
Primary
Concomitant

Drug Data