Bevacizumab combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Other Serious 1/10/2007 43 Female 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 2/28/2007 Female 4/19/2007 Physician United States
Primary
Concomitant
Medical Device Complication Hospitalization 3/19/2007 27 Female 4/23/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 5/27/2007 Female 6/11/2007 Physician United States
Primary
Concomitant
Dehydration Life Threatening 6/21/2007 58 Female 302 lb 7/2/2007 Other Health Professional United States
Primary
Secondary
Dehydration Life Threatening 6/21/2007 58 Female 302 lb 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 7/13/2007 Female 7/27/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 6/21/2007 58 Female 302 lb 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/10/2007 43 Female 8/7/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/3/2007 53 Female 148 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 5/2/2007 Female 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/5/2007 59 Female 199 lb 9/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 9/10/2007 42 Female 9/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/28/2007 Female 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 7/13/2007 Female 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/5/2007 59 Female 199 lb 10/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/5/2007 59 Female 199 lb 10/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 9/10/2007 72 Female 194 lb 10/9/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/5/2007 59 Female 199 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/5/2007 59 Female 199 lb 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/23/2007 Male 10/15/2007 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/23/2007 Male 10/15/2007 Physician United Kingdom
Primary
Secondary
Death Death 10/1/2007 Male 11/12/2007 Physician United States
Primary
Secondary
Death Death 10/1/2007 Male 11/12/2007 Physician United States
Primary
Secondary
Large Intestinal Ulcer Hospitalization 9/11/2007 55 Female 181 lb 11/26/2007 Physician United States
Primary
Secondary
Cardiomyopathy Life Threatening 11/13/2007 60 12/4/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 9/10/2007 72 Female 194 lb 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Life Threatening 11/13/2007 60 134 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 7/3/2007 53 Female 148 lb 1/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomyopathy Life Threatening 11/13/2007 60 134 lb 1/2/2008 Physician United States
Primary
Secondary
Concomitant
Tumour Ulceration Hospitalization 2/5/2008 Female 150 lb 2/11/2008 Physician Ukraine
Primary
Secondary
Tumour Ulceration Hospitalization 2/5/2008 Female 150 lb 2/20/2008 Physician Ukraine
Primary
Secondary
Pericardial Effusion Hospitalization 5/2/2007 Female 2/20/2008 Physician United States
Primary
Secondary
Concomitant
Tumour Ulceration Hospitalization 2/4/2008 Female 150 lb 3/14/2008 Physician Ukraine
Primary
Secondary
Death Death 3/31/2008 55 Female 4/15/2008 Physician United Kingdom
Primary
Secondary
Death Death 3/31/2008 55 Female 4/15/2008 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 5/1/2008 Physician Australia
Primary
Concomitant
Sepsis Death 6/28/2007 49 Female 198 lb 5/1/2008 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Life Threatening 11/13/2007 60 134 lb 5/20/2008 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/9/2008 Female 134 lb 5/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 5/9/2008 Female 134 lb 6/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/13/2008 64 Female 142 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 4/19/2007 Female 7/16/2008 Physician United Kingdom
Primary
Secondary
Trismus Other Serious 5/1/2008 Female 7/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/19/2008 65 Female 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/7/2008 Female 8/21/2008 Physician United Kingdom
Primary
Secondary
Diverticulitis Hospitalization 8/7/2008 Female 8/27/2008 Physician United Kingdom
Primary
Secondary
Pancreatitis Hospitalization 8/13/2008 Female 8/27/2008 Consumer United Kingdom
Primary
Secondary
Sepsis Hospitalization 8/7/2008 Female 9/5/2008 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 7/3/2008 Female 9/5/2008 Physician France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 6/25/2008 Female 9/18/2008 Physician France
Primary
Secondary
Concomitant
Hypotension Hospitalization 3/23/2008 46 Female 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 6/25/2008 Female 10/14/2008 Physician France
Primary
Secondary
Concomitant
Myalgia Other Serious 9/21/2006 Female 10/15/2008 Physician United Kingdom
Primary
Secondary
Haemoptysis Death 3/31/2008 Female 10/15/2008 Physician United Kingdom
Primary
Secondary
Haemoptysis Death 3/31/2008 Female 10/15/2008 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 9/30/2008 Female 10/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Lymphopenia Other Serious 9/19/2008 10/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Lymphopenia Other Serious 9/19/2008 10/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Ejection Fraction Decreased Other Serious 10/4/2006 10/16/2008 Physician United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphopenia Other Serious 8/27/2008 10/16/2008 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Phlebitis Disability 9/30/2008 Female 10/21/2008 Physician United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 Female 10/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 7/1/2008 62 Female 129 lb 10/24/2008 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/15/2008 United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 10/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 10/31/2008 Consumer United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 9/13/2008 Male 204 lb 11/4/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/16/2007 Female 11/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/30/2008 Female 11/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Catheter Related Infection Hospitalization 10/6/2008 Female 11/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/7/2008 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/31/2008 United Kingdom
Primary
Secondary
Septic Shock Death 10/27/2008 78 Male 11/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Proctitis Other Serious 10/10/2008 Female 11/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/7/2008 Female 11/13/2008 Physician United Kingdom
Primary
Secondary
Hypotension Hospitalization 3/23/2008 46 Female 11/17/2008 Physician United States
Primary
Secondary
Concomitant
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/18/2008 Consumer United Kingdom
Primary
Secondary
Pyrexia Other Serious 4/16/2007 Female 11/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/19/2008 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/19/2008 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Hypoxia Hospitalization 7/29/2008 Male 11/19/2008 Physician United Kingdom
Primary
Secondary
Hypoxia Hospitalization 7/29/2008 Male 11/19/2008 Physician United Kingdom
Primary
Secondary
Superior Vena Caval Occlusion Hospitalization 2/7/2008 50 Female 128 lb 11/20/2008 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 4/9/2008 Male 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Superior Vena Caval Occlusion Hospitalization 2/7/2008 50 Female 128 lb 11/26/2008 Physician United States
Primary
Secondary
Concomitant
Bronchospasm Hospitalization 5/5/2008 Female 12/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 10/14/2008 Female 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Radiation Skin Injury Other Serious 5/1/2007 42 Female 12/11/2008 Physician United States
Primary
Concomitant
Lacrimation Increased Other Serious 10/18/2006 12/11/2008 Physician United States
Primary
Concomitant
Blood Amylase Increased Other Serious 1/19/2007 12/11/2008 Physician United States
Primary
Secondary
Sepsis Hospitalization 8/12/2008 Female 12/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 11/27/2008 Female 12/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 1/2/2007 12/12/2008 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 11/16/2006 Female 12/15/2008 Physician United States
Primary
Concomitant
Large Intestinal Haemorrhage Hospitalization 2/3/2008 Male 12/15/2008 Physician United States
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 12/15/2008 Other Health Professional Italy
Primary
Secondary
Neutropenic Infection Other Serious 11/28/2008 Female 12/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Nail Disorder Other Serious 1/3/2007 12/15/2008 Physician United States
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 4/18/2008 Male 12/15/2008 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 5/6/2008 12/15/2008 Physician United States
Primary
Secondary
Hyperbilirubinaemia Other Serious 2/8/2007 12/16/2008 Physician United States
Primary
Concomitant
Insomnia Other Serious 7/9/2007 12/16/2008 Physician United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 10/27/2006 12/16/2008 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 9/6/2006 12/16/2008 Physician United States
Primary
Concomitant
Tinnitus Other Serious 10/15/2006 12/16/2008 Physician United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 11/27/2008 Female 12/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypocalcaemia Other Serious 7/16/2007 12/17/2008 Physician United States
Primary
Concomitant
Menstruation Irregular Other Serious 12/1/2006 12/18/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 11/28/2008 Female 12/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/4/2008 Female 12/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization 8/12/2008 69 Female 159 lb 12/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Surgery Hospitalization 8/1/2008 69 Female 159 lb 12/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/4/2008 Female 12/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/8/2008 28 Male 185 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Phlebitis Disability 9/30/2008 Female 12/24/2008 Physician United Kingdom
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 9/6/2006 12/24/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 11/27/2008 Female 12/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Life Threatening 10/2/2007 60 Female 134 lb 12/24/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 11/28/2008 Female 12/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Life Threatening 11/27/2008 Female 12/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization 8/1/2008 69 Female 159 lb 1/2/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/8/2008 28 Male 185 lb 1/9/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/27/2008 Female 1/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 11/27/2008 Female 1/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 11/28/2008 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 Female 1/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/12/2009 Female 1/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 1/12/2009 Female 1/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Periorbital Cellulitis Hospitalization Female 2/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/12/2009 Female 2/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 2/5/2009 Consumer United Kingdom
Primary
Secondary
Asthenia Other Serious 2/6/2009 Consumer United Kingdom
Primary
Secondary
Rash Other Serious 12/29/2008 Female 2/10/2009 Physician United States
Primary
Secondary
Pyrexia Hospitalization 12/23/2008 53 Female 192 lb 2/10/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/24/2009 Female 2/11/2009 Consumer United Kingdom
Primary
Secondary
Death Hospitalization 1/23/2009 65 Female 157 lb 2/11/2009 Physician United States
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 1/14/2009 Female 2/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Periorbital Cellulitis Hospitalization Female 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/12/2008 Female 2/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 8/1/2008 2/13/2009 Physician Germany
Primary
Secondary

Drug Data