Beta Blocking Agents combined with Calcium Channel Blockers

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Depression 5/1/2006 Male 8/25/2006 Physician United States
Primary
Concomitant
Prescribed Overdose Other Serious Female 2/3/2007 Physician Canada
Primary
Concomitant
Vomiting Other Serious 9/1/2006 45 Male 4/14/2007 United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 65 Female 8/10/2007 Physician Israel
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 8/1/2007 2/1/2008 Physician Canada
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 12/1/2007 2/3/2008 Physician
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 12/7/2007 52 Female 2/6/2008 Physician
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 2/9/2008 Physician
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 8/1/2007 2/16/2008 Physician Canada
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 1/1/2006 59 Male 2/29/2008 Other Health Professional Japan
Primary
Concomitant
Weight Decreased 11/1/2007 71 Male 177 lb 1/10/2008 Consumer United States
Primary
Concomitant
Proteinuria Other Serious 1/9/2008 3/16/2008 Physician
Primary
Concomitant
Microalbuminuria Other Serious 5/1/2008 6/12/2008 Physician Canada
Primary
Concomitant
Vasoconstriction Disability 11/27/2007 63 Male 251 lb 6/24/2008 Physician Austria
Primary
Secondary
Concomitant
Microalbuminuria Other Serious 4/1/2008 7/11/2008 Physician Canada
Primary
Concomitant
Nasal Congestion Other Serious Male 161 lb 7/14/2008 Pharmacist Germany
Primary
Concomitant
Microalbuminuria Other Serious 4/1/2008 7/16/2008 Physician Canada
Primary
Concomitant
Renal Artery Stenosis Other Serious 10/4/2007 Male 12/12/2008 Other Health Professional Canada
Primary
Concomitant
Vertigo Hospitalization 11/28/2008 Male 3/6/2009 France
Primary
Concomitant
Percutaneous Coronary Intervention Other Serious 2/3/2008 4/1/2009 Physician Canada
Primary
Concomitant
Hyponatraemia Other Serious 1/1/2009 72 Male 4/6/2009 Physician Belgium
Primary
Concomitant
Interacting
Vascular Stent Insertion Other Serious 2/3/2008 Male 4/15/2009 Physician Canada
Primary
Concomitant
Renal Impairment Hospitalization 1/13/2009 Male 172 lb 8/14/2009 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 1/1/2008 Male 172 lb 9/29/2009 Physician Germany
Primary
Concomitant
Infarction Other Serious 11/13/2009 Physician Canada
Primary
Concomitant
Myocardial Infarction Other Serious 7/1/2009 Male 11/18/2009 Physician Canada
Primary
Concomitant
Atrial Flutter Other Serious Male 12/16/2009 Physician United States
Primary
Secondary
Renal Failure Other Serious 1/27/2010 Physician Canada
Primary
Concomitant
Death Death Male 190 lb 1/29/2010 Physician Germany
Primary
Concomitant
Ventricular Fibrillation Death 1/1/2010 2/19/2010 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 10/23/2009 Male 190 lb 2/19/2010 Physician Germany
Primary
Concomitant
Wound Other Serious 9/1/2009 Male 218 lb 3/9/2010 Physician Germany
Primary
Concomitant
Hypertensive Crisis Other Serious 10/30/2009 Male 247 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/12/2010 Physician Canada
Primary
Concomitant
Weight Increased Other Serious Female 148 lb 3/16/2010 Physician France
Primary
Concomitant
Hypertensive Crisis Hospitalization 12/12/2008 Female 170 lb 3/18/2010 Physician Germany
Primary
Concomitant
Stridor Other Serious 10/23/2009 Male 190 lb 3/19/2010 Physician Germany
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 8/15/2008 78 Female 3/24/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 3/2/2009 Female 187 lb 3/31/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Other Serious 9/1/2009 60 Male 218 lb 4/2/2010 Physician Germany
Primary
Concomitant
Thrombosis In Device Other Serious 4/1/2010 Other Health Professional United States
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 2/18/2010 4/12/2010 Physician Canada
Primary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 4/19/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 72 Male 4/15/2010 Physician Korea, Republic Of
Primary
Concomitant
Vascular Graft Other Serious 1/1/2005 73 Male 238 lb 4/26/2010 Physician Germany
Primary
Secondary
Concomitant
Vascular Graft Other Serious Male 225 lb 4/26/2010 Physician Germany
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 2/18/2010 82 Female 5/7/2010 Physician Canada
Primary
Concomitant
Vascular Graft Other Serious 5/11/2010 Physician Canada
Primary
Concomitant
Rehabilitation Therapy Hospitalization 4/1/2009 71 Female 198 lb 5/14/2010 Physician Germany
Primary
Concomitant
Vascular Graft Other Serious 5/18/2010 Physician Canada
Primary
Concomitant
Hypertensive Crisis Other Serious 12/12/2008 74 Female 170 lb 5/27/2010 Physician Germany
Primary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 5/29/2010 Physician Germany
Primary
Secondary
Concomitant
Withdrawal Syndrome Life Threatening 4/1/2009 71 Female 198 lb 5/31/2010 Physician Germany
Primary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 6/3/2010 Physician Germany
Primary
Secondary
Concomitant
Vascular Graft Other Serious 5/24/2010 70 Male 225 lb 6/6/2010 Physician Germany
Primary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 6/10/2010 Physician Germany
Primary
Secondary
Concomitant
Inflammatory Bowel Disease Other Serious 6/17/2010 Physician Canada
Primary
Concomitant
Hypertensive Crisis Other Serious 12/12/2008 74 Female 170 lb 6/17/2010 Physician Germany
Primary
Concomitant
Hypertension Other Serious 7/13/2010 Physician Canada
Primary
Concomitant
Hypertension Other Serious 7/19/2010 Physician Canada
Primary
Concomitant
Dyspnoea Other Serious 4/14/2010 70 Male 225 lb 8/27/2010 Physician Germany
Primary
Concomitant
Supraventricular Extrasystoles Other Serious Male 181 lb 9/14/2010 Physician Germany
Primary
Secondary
Concomitant
Muscle Haemorrhage Hospitalization 7/16/2009 81 Female 223 lb 9/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Cancer Metastatic Life Threatening 8/22/2010 62 Male 9/27/2010 Physician United States
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 2/6/2009 70 Male 181 lb 10/1/2010 Physician Germany
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 10/3/2009 89 Male 141 lb 11/10/2010 Other Health Professional United States
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 11/17/2009 11/19/2010 Physician Canada
Primary
Concomitant
Death Death 8/19/2010 69 Female 12/9/2010 Other Health Professional United States
Primary
Concomitant
Lactic Acidosis Hospitalization 12/12/2010 78 Female 1/5/2011 Other Health Professional Italy
Primary
Concomitant
Lactic Acidosis Hospitalization 12/12/2010 78 Female 1/5/2011 Other Health Professional Italy
Primary
Concomitant
Lactic Acidosis Hospitalization 12/12/2010 87 Female 1/6/2011 Other Health Professional Italy
Primary
Concomitant
Coronary Artery Disease Other Serious 1/7/2011 Physician Canada
Primary
Concomitant
No Adverse Event Other Serious 1/18/2011 Physician Canada
Primary
Concomitant
Oliguria Other Serious 11/6/2010 74 Male 1/28/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Interacting
Coronary Artery Disease Other Serious 2/1/2011 Physician Canada
Primary
Concomitant
Hypertensive Crisis Other Serious 12/12/2008 74 Female 170 lb 2/21/2011 Physician Germany
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 7/18/2010 Male 3/4/2011 Physician Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 3/7/2011 Physician Philippines
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 7/18/2010 60 Male 155 lb 3/22/2011 Consumer Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/25/2011 59 Male 3/31/2011 Physician Germany
Primary
Concomitant
Hypotension Other Serious 2/1/2011 54 Male 4/8/2011 Physician Canada
Primary
Concomitant
Hypertensive Crisis Other Serious 12/12/2008 74 Female 170 lb 4/20/2011 Other Health Professional Germany
Primary
Concomitant
Death Death 89 Female 137 lb 4/21/2011 Physician United Arab Emirates
Primary
Concomitant
Withdrawal Hypertension Other Serious 4/24/2009 65 Male 181 lb 4/27/2011 Physician Germany
Primary
Secondary
Concomitant
Heart Rate Decreased Hospitalization 4/24/2009 65 Male 181 lb 4/29/2011 Physician Germany
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 2/1/2011 54 Male 5/4/2011 Physician Canada
Primary
Concomitant
Peptic Ulcer Haemorrhage Hospitalization 5/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Diarrhoea 80 Female 5/30/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 3/24/2010 60 Female 256 lb 5/31/2011 Physician Germany
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 10/1/2007 Male 6/11/2011 Physician Canada
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 6/21/2011 Physician Canada
Primary
Concomitant
Malaise Hospitalization 6/11/2011 70 Male 6/24/2011 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 6/11/2011 70 Male 6/27/2011 Physician United States
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious Female 6/29/2011 Physician Canada
Primary
Concomitant
Blood Pressure Systolic Increased Other Serious 7/4/2011 Physician Canada
Primary
Concomitant
Gouty Arthritis Hospitalization 3/24/2010 60 Female 256 lb 7/5/2011 Physician Germany
Primary
Concomitant
Low Density Lipoprotein Decreased Other Serious 7/13/2011 Physician Canada
Primary
Concomitant
Hypertension Other Serious 5/1/2010 69 Male 209 lb 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Fall Hospitalization 4/9/2011 62 Male 7/25/2011 Physician Sweden
Primary
Secondary
Concomitant
Bronchitis Other Serious Female 8/8/2011 Physician Canada
Primary
Concomitant
Creatinine Urine Increased Hospitalization 2/1/2011 72 Male 154 lb 8/9/2011 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 2/1/2011 72 Male 154 lb 8/9/2011 Physician Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 9/1/2009 72 Male 161 lb 8/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 2/27/2009 67 Male 8/10/2011 Physician United States
Primary
Concomitant
Asthenia Hospitalization 7/28/2011 8/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/1/2011 79 Female 8/16/2011 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Shortened Hospitalization 2/1/2011 72 Male 181 lb 8/25/2011 Physician Germany
Primary
Secondary
Concomitant
Creatinine Urine Increased Hospitalization 2/1/2011 72 Male 181 lb 8/25/2011 Physician Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 9/1/2009 72 Male 161 lb 8/29/2011 Other Health Professional Germany
Primary
Concomitant
Hypocalcaemia Other Serious 1/1/2011 89 Female 9/8/2011 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 6/11/2011 70 Male 175 lb 9/8/2011 Physician United States
Primary
Concomitant
Cardiomegaly Hospitalization 2/4/2011 79 Female 9/13/2011 Physician Hungary
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/1/2009 89 Male 141 lb 9/20/2011 Other Health Professional United States
Primary
Concomitant
Heart Rate Increased Hospitalization 3/24/2010 60 Female 256 lb 9/21/2011 Physician Germany
Primary
Concomitant
Drug Ineffective Other Serious Male 9/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cushingoid Other Serious Male 9/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cushingoid Other Serious Male 9/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Intracranial Other Serious 81 150 lb 10/4/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 10/19/2011 Physician Canada
Primary
Concomitant
Diabetes Mellitus Other Serious Male 10/20/2011 Physician Canada
Primary
Concomitant
Blood Pressure Systolic Increased Other Serious 10/21/2011 Physician Canada
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/3/2011 68 Male 161 lb 11/16/2011 Physician Germany
Primary
Secondary
Concomitant
Dilatation Atrial Other Serious 12/1/2008 60 Male 201 lb 12/2/2011 Physician France
Primary
Concomitant
Blood Creatinine Increased Other Serious 12/8/2011 Physician Canada
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 12/14/2011 Physician Canada
Primary
Concomitant
Albumin Urine Present Hospitalization 2/1/2011 72 Male 181 lb 12/16/2011 Physician Germany
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 6/15/2010 87 12/16/2011 Physician Canada
Primary
Concomitant
Malignant Pleural Effusion Death 11/21/2011 51 Male 209 lb 12/19/2011 Physician Germany
Primary
Concomitant
Blood Pressure Increased Other Serious 12/21/2011 Physician Canada
Primary
Concomitant
Malignant Pleural Effusion Hospitalization 11/21/2011 51 Male 209 lb 12/27/2011 Physician Germany
Primary
Concomitant
Anaemia Death 11/21/2011 51 Male 209 lb 12/28/2011 Physician Germany
Primary
Concomitant
Coronary Artery Disease Other Serious 1/10/2012 Physician Canada
Primary
Concomitant
Anaemia Hospitalization 4/5/2008 64 Male 1/16/2012 Physician Canada
Primary
Concomitant
Neoplasm Malignant Death 1/8/2010 75 Male 1/16/2012 Physician United States
Primary
Concomitant
Hypotension Hospitalization 4/12/2008 64 Male 1/16/2012 Other Health Professional Canada
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 2/15/2008 78 Male 1/16/2012 Physician United States
Primary
Concomitant
Pneumonia Death 2/7/2010 81 Male 1/16/2012 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 11/2/2008 67 Male 1/16/2012 Physician United States
Primary
Concomitant
Blood Pressure Increased 1/20/2012 Physician Canada
Primary
Concomitant
Renal Failure Life Threatening 7/7/2011 66 Male 192 lb 1/27/2012 Physician Germany
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 8/11/2011 75 Male 2/2/2012 Physician France
Primary
Concomitant
Noninfectious Peritonitis Other Serious 9/10/2010 52 Male 170 lb 2/2/2012 Physician Germany
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 8/1/2007 Male 218 lb 2/3/2012 Physician Germany
Primary
Secondary
Concomitant
Blood Triglycerides Increased Life Threatening 7/7/2011 66 Male 192 lb 2/3/2012 Physician Germany
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 8/1/2007 Male 218 lb 2/3/2012 Physician Germany
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 8/1/2007 Male 218 lb 2/8/2012 Physician Germany
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 8/1/2007 Male 218 lb 2/8/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Death 2/13/2012 Physician Canada
Primary
Concomitant
Malaise Hospitalization 11/9/2008 58 Female 2/13/2012 Physician Netherlands
Primary
Concomitant
Cellulitis Hospitalization 11/23/2008 58 Female 2/13/2012 Physician Netherlands
Primary
Concomitant

Drug Data