Benztropine Mesylate combined with Clozapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Hospitalization 9/15/2005 44 Female 1/10/2006 Consumer United Kingdom
Primary
Secondary
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased 12/21/2005 Male 150 lb 1/13/2006 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Death 12/26/2005 63 Male 1/16/2006 United States
Primary
Concomitant
Respiratory Arrest Hospitalization 6/19/2005 44 Male 254 lb 1/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Required Intervention 42 Male 2/8/2006 United States
Primary
Concomitant
Respiratory Disorder Death 12/26/2005 63 Male 2/16/2006 United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2006 64 Female 2/24/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Death 1/7/2006 38 Female 3/7/2006 United States
Primary
Concomitant
Death Death 2/13/2006 44 Male 3/8/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 8/9/2005 54 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Leukopenia Required Intervention 9/28/2005 42 Female 328 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 2/28/2006 72 Male 3/22/2006 United States
Primary
Concomitant
Unevaluable Event Death 8/7/2005 54 Female 170 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Required Intervention 11/14/2004 35 Female 12/14/2005 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 8/16/2005 57 Female 180 lb 12/14/2005 Physician United States
Primary
Concomitant
Neutropenia Required Intervention 2/15/2005 55 Female 186 lb 4/11/2005 Pharmacist United States
Primary
Concomitant
Drug Ineffective Hospitalization 10/15/2004 35 Female 239 lb 12/7/2004 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 8/27/2005 35 Female 210 lb 12/14/2005 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Death 1/7/2006 38 Female 148 lb 3/28/2006 United States
Primary
Concomitant
Death Death 3/6/2006 54 Female 3/27/2006 United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 8/13/2005 29 Male 213 lb 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sluggishness Other Serious 37 Male 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Death 3/1/2006 72 Male 4/7/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 8/22/2005 42 Male 4/7/2006 United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2006 64 Female 125 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2006 64 Female 125 lb 4/4/2006 Physician United States
Primary
Concomitant
Posturing Life Threatening 3/21/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Hypertension Death 4/1/2006 46 Female 5/19/2006 United States
Primary
Concomitant
Subdural Haematoma Death 4/30/2006 34 Male 5/22/2006 United States
Primary
Concomitant
Failure To Thrive Death 5/15/2006 58 Male 5/31/2006 United States
Primary
Concomitant
Medication Error Other Serious 47 Male 4/21/2006 Consumer United States
Primary
Concomitant
Death Death 4/15/2006 52 Male 6/6/2006 United States
Primary
Concomitant
Death Death 1/1/2006 55 Female 6/14/2006 United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 8/13/2005 29 Male 212 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 4/30/2006 34 Male 205 lb 6/29/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 5/30/2006 55 Female 7/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 49 Male 4/3/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/9/2006 48 Male 207 lb 5/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/3/2006 18 Female 4/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/28/2005 21 Male 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/18/2006 46 Female 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/16/2006 29 Male 170 lb 4/5/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 43 Male 150 lb 3/21/2006 United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 23 Male 180 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/2/2006 49 Male 3/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/3/2006 20 Female 179 lb 3/28/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/23/2006 42 Female 6/12/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/1/2005 44 Male 163 lb 6/30/2006 United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 12/13/2005 37 Female 209 lb 2/28/2006 United States
Primary
Concomitant
Granulocytopenia Life Threatening 10/5/2005 51 Female 1/25/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/9/2005 29 Male 155 lb 6/20/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/16/2005 43 Male 1/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/13/2005 44 Male 197 lb 1/18/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/4/2005 42 Male 5/24/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/14/2005 47 Male 6/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/10/2005 45 Female 1/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/1/2005 26 Female 3/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/6/2005 47 Male 2/27/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/16/2005 43 Female 2/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/3/2005 47 Male 2/14/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/17/2005 19 Male 6/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/14/2005 40 Female 2/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 37 Male 2/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/17/2005 35 Male 1/30/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/13/2006 50 Female 5/12/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/24/2005 39 Male 1/30/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/18/2005 30 Male 1/30/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/17/2005 47 Male 3/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/26/2005 16 Male 1/31/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/12/2005 27 Male 2/10/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/14/2005 29 Male 150 lb 3/22/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 7/21/2005 46 Male 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/10/2005 48 Male 5/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/8/2005 47 Male 2/6/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/17/2006 38 Male 115 lb 6/6/2006 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 4/13/2006 29 Male 218 lb 5/23/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 4/4/2006 44 Female 5/23/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 4/5/2006 43 Female 140 lb 6/12/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/10/2006 31 Male 300 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/27/2006 29 Male 5/12/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/19/2005 39 Female 1/13/2006 United States
Primary
Concomitant
Tonic Convulsion 29 Male 212 lb 1/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Leukopenia Required Intervention 10/13/2005 50 Male 281 lb 1/23/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/29/2005 24 Male 192 lb 2/3/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/6/2005 44 Male 180 lb 1/24/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/29/2005 53 Female 1/5/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 34 Male 150 lb 4/24/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/8/2005 33 Male 153 lb 3/14/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/21/2005 52 Female 217 lb 1/23/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/1/2005 35 Male 190 lb 1/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/12/2005 49 Male 220 lb 1/16/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Death 7/8/2006 45 Male 7/26/2006 United States
Primary
Concomitant
Granulocytopenia 1/3/2006 60 Male 5/9/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 50 Female 2/15/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/28/2006 36 Male 4/6/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 3/21/2006 49 Male 175 lb 5/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/13/2006 56 Female 180 lb 5/11/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 3/7/2006 38 Male 158 lb 6/1/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/17/2006 19 Male 4/11/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/20/2006 29 Male 6/12/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/8/2005 36 Female 1/6/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/6/2005 19 Female 6/16/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/29/2005 55 Male 174 lb 3/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 40 Female 3/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/13/2005 58 Male 1/9/2006 Consumer United States
Primary
Concomitant
Phlebotomy Death 7/20/2006 53 Male 9/12/2006 United States
Primary
Concomitant
Granulocytopenia Death 1/1/2006 56 Male 9/18/2006 United States
Primary
Concomitant
Pneumonia Hospitalization 9/15/2005 44 Female 10/3/2006 Consumer United Kingdom
Primary
Secondary
Cardiac Failure Congestive Death 7/8/2006 45 Male 153 lb 9/28/2006 United States
Primary
Concomitant
Syncope Required Intervention 8/6/2006 48 Male 170 lb 10/5/2006 United States
Primary
Concomitant
Intestinal Obstruction Death 10/9/2006 22 Male 10/18/2006 United States
Primary
Concomitant
Death Death 10/8/2006 59 Male 10/27/2006 United States
Primary
Concomitant
Septic Shock Death 9/9/2006 28 Male 11/3/2006 United States
Primary
Concomitant
Intestinal Obstruction Death 10/5/2006 22 Male 11/14/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 4/30/2005 38 Male 12/2/2006 Physician Canada
Primary
Concomitant
Vomiting Life Threatening 9/1/2006 46 Male 150 lb 11/22/2006 Pharmacist United States
Primary
Concomitant
Malaise Death 7/21/2006 53 Male 193 lb 12/5/2006 Other Health Professional United States
Primary
Concomitant
Septic Shock Death 9/9/2006 28 Male 1/2/2007 United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/24/2006 54 Male 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 4/12/2007 23 Male 5/17/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 34 Male 9/4/2007 Other Health Professional Singapore
Primary
Concomitant
Necrotising Colitis Life Threatening 34 Male 9/21/2007 Physician Singapore
Primary
Concomitant
White Blood Cell Count Increased Death 36 Male 11/12/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 8/25/2007 31 Male 180 lb 12/3/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Male 12/7/2007 Physician United States
Primary
Concomitant
Lethargy Hospitalization 11/1/2007 51 Male 204 lb 4/1/2008 Consumer United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 11/1/2007 51 Male 204 lb 4/23/2008 Consumer United States
Primary
Secondary
Concomitant
Metastases To Breast Other Serious 3/1/2008 Female 6/19/2008 Other Health Professional United States
Primary
Concomitant
Metastases To Breast Other Serious 3/1/2008 Female 6/27/2008 Other Health Professional United States
Primary
Concomitant
Breast Cancer Metastatic Other Serious 3/1/2008 56 Female 7/14/2008 Other Health Professional United States
Primary
Concomitant
Parkinsonism Hospitalization 8/1/2008 50 Male 170 lb 9/4/2008 Physician United States
Primary
Concomitant
Parkinsonism Hospitalization 8/1/2008 50 Male 170 lb 11/26/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 8/3/2008 49 Male 212 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Drug Toxicity Death 43 Male 12/29/2008 Physician United States
Primary
Secondary
Vomiting Hospitalization 1/18/2008 15 Female 163 lb 11/25/2008 Physician United States
Primary
Concomitant
Completed Suicide Death 43 Male 1/13/2009 United States
Primary
Secondary
Completed Suicide Death 43 Male 1/15/2009 Physician United States
Primary
Secondary
Gastrointestinal Haemorrhage Other Serious 11/14/2008 Female 124 lb 2/5/2009 Physician United States
Primary
Concomitant
Completed Suicide Death 43 Male 2/13/2009 Physician United States
Primary
Secondary
Tic Other Serious 2/19/2009 43 Male 196 lb 2/27/2009 Pharmacist United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 36 Female 3/30/2009 Physician Korea, Republic Of
Primary
Concomitant
Orthopnoea Hospitalization 9/21/2009 39 Female 186 lb 9/29/2009 United States
Primary
Concomitant
Myoclonus Required Intervention 7/15/2008 54 Male 225 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Neutropenia Required Intervention 11/3/2009 37 Male 180 lb 11/17/2009 Other Health Professional United States
Primary
Concomitant
Laboratory Test Abnormal Other Serious 3/18/2010 46 Male 185 lb 3/19/2010 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Death 282 lb 4/15/2010 United States
Primary
Concomitant
Granulocytopenia Other Serious 5/7/2009 51 Female 6/24/2010 United States
Primary
Concomitant
Death Death 53 Male 6/24/2010 Pharmacist United States
Primary
Concomitant

Drug Data