Baraclude combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Exfoliation 7/1/2007 54 Male 125 lb 10/12/2007 United States
Primary
Concomitant
Hepatic Neoplasm Malignant Death 7/14/2009 58 Male 163 lb 8/24/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/2/2009 46 Male 157 lb 8/24/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 8/19/2009 56 Male 168 lb 9/21/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 6/6/2009 46 Male 152 lb 10/14/2009 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 7/14/2009 60 Male 126 lb 11/4/2009 Physician Japan
Primary
Concomitant
Hyperammonaemia Disability 9/8/2009 60 Male 119 lb 11/11/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2009 69 Male 128 lb 11/11/2009 Physician Japan
Primary
Concomitant
Rash Life Threatening 7/10/2009 64 Male 11/25/2009 Physician Japan
Primary
Concomitant
Hyperammonaemia Disability 9/8/2009 60 Male 119 lb 12/1/2009 Physician Japan
Primary
Concomitant
Hypertension Death 9/20/2009 57 Male 176 lb 12/3/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 12/18/2009 Physician Japan
Primary
Concomitant
Stomatitis Disability 8/12/2009 39 Female 112 lb 12/28/2009 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 7/14/2009 60 Male 126 lb 12/29/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/3/2009 46 Male 152 lb 1/8/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 12/7/2009 67 Male 1/13/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/31/2009 59 Male 146 lb 1/25/2010 Physician Japan
Primary
Secondary
Hypothyroidism Life Threatening 11/25/2009 69 Female 154 lb 2/4/2010 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 11/19/2009 56 Male 2/11/2010 Consumer France
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 11/22/2009 61 Male 146 lb 2/24/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/12/2010 68 Male 146 lb 2/25/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 3/25/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 9/21/2009 71 Male 168 lb 3/26/2010 Physician Japan
Primary
Concomitant
Metastases To Stomach Hospitalization 1/1/2010 63 Male 174 lb 3/31/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/6/2009 73 Male 130 lb 4/13/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 9/21/2009 71 Male 168 lb 4/15/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/24/2009 83 Male 115 lb 4/20/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 4/21/2010 Physician Japan
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 11/22/2009 61 Male 146 lb 4/28/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 4/28/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 6/1/2009 56 Male 157 lb 5/5/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/5/2009 46 Male 152 lb 5/11/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 6/1/2009 56 Male 157 lb 5/11/2010 Physician Japan
Primary
Concomitant
Lipase Increased Hospitalization 12/1/2009 55 Male 132 lb 5/13/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 1/14/2010 79 Male 139 lb 5/24/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/31/2009 71 Male 168 lb 5/24/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 4/16/2010 61 Male 5/24/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 4/16/2010 61 Male 6/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 7/27/2009 39 Female 112 lb 6/3/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 2/12/2010 68 Male 146 lb 6/7/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2009 69 Male 128 lb 6/7/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 2/12/2010 68 Male 146 lb 6/16/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 6/23/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/24/2009 83 Male 115 lb 7/7/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 6/1/2009 56 Male 157 lb 7/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 7/27/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 6/17/2010 36 Male 150 lb 7/26/2010 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Death 64 Male 7/30/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 8/3/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 6/17/2010 36 Male 150 lb 8/3/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 11/1/2009 57 Male 130 lb 8/10/2010 Physician Japan
Primary
Concomitant
Hyperbilirubinaemia Death 5/28/2010 64 Male 8/12/2010 Physician Japan
Primary
Concomitant
Electrolyte Imbalance Hospitalization 1/10/2010 66 Male 8/16/2010 Physician Italy
Primary
Concomitant
Electrolyte Imbalance Hospitalization 1/10/2010 66 Male 8/20/2010 Physician Italy
Primary
Concomitant
Electrolyte Imbalance Hospitalization 1/10/2010 66 Male 8/23/2010 Physician Italy
Primary
Concomitant
Pyrexia Other Serious 7/10/2009 73 Male 165 lb 8/24/2010
Primary
Concomitant
Hyperbilirubinaemia Death 4/1/2010 64 Male 9/3/2010 Physician Japan
Primary
Concomitant
Hyperbilirubinaemia Death 4/1/2010 64 Male 9/8/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/20/2010 51 Male 150 lb 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 5/1/2010 63 Male 9/14/2010 Consumer Korea, Republic Of
Primary
Concomitant
Rash Other Serious 8/31/2009 71 Male 168 lb 9/15/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 5/6/2010 45 Male 139 lb 9/20/2010 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 8/24/2010 64 Male 128 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 4/28/2010 66 Male 146 lb 10/5/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 4/21/2010 56 Male 115 lb 10/25/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 7/10/2009 73 Male 165 lb 10/29/2010 Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 10/21/2009 61 Male 181 lb 11/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/13/2010 60 Male 11/4/2010 Physician Japan
Primary
Concomitant
Liver Disorder Death 8/22/2010 63 Male 108 lb 11/8/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 7/10/2009 73 Male 165 lb 11/18/2010 Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/27/2010 65 Male 165 lb 11/19/2010 Physician Japan
Primary
Concomitant
Dysgeusia Other Serious 10/11/2010 68 Male 130 lb 1/3/2011 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/16/2010 56 Male 148 lb 1/10/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/14/2010 63 Male 126 lb 1/13/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 12/14/2010 63 Male 121 lb 1/18/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 4/1/2010 55 Male 115 lb 1/28/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 12/15/2010 61 Male 106 lb 1/28/2011 Physician Japan
Primary
Concomitant
Hypothyroidism Hospitalization 11/25/2009 69 Female 153 lb 1/28/2011 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 12/16/2010 56 Male 148 lb 2/15/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 11/16/2009 69 Female 154 lb 2/16/2011 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 10/11/2010 68 Male 130 lb 2/10/2011 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 11/7/2010 61 Female 95 lb 2/11/2011 Physician Japan
Primary
Concomitant
Dehydration Other Serious 11/7/2010 61 Female 95 lb 2/24/2011 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 12/20/2010 68 Male 357 lb 3/7/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Death 2/25/2011 Male 3/15/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 7/13/2010 59 Male 3/21/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 2/1/2011 62 Male 168 lb 3/22/2011 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 12/16/2010 56 Male 148 lb 3/24/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hepatic Failure Death 3/8/2011 53 Male 209 lb 4/4/2011 Physician Japan
Primary
Concomitant
Sepsis Death 3/27/2011 30 Male 4/7/2011 Physician Philippines
Primary
Concomitant
Keratoconjunctivitis Sicca Life Threatening 7/10/2009 63 Male 4/19/2011 Physician Japan
Primary
Concomitant
Hyperkeratosis Disability 2/18/2011 76 Male 5/24/2011 Other Health Professional Italy
Primary
Concomitant
Pancreatic Enzymes Increased Death 7/3/2009 49 Male 159 lb 5/25/2011 Physician Japan
Primary
Concomitant
Hepatitis B Hospitalization 12/3/2010 75 Male 110 lb 6/1/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/27/2010 65 Male 165 lb 6/6/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/5/2011 62 Male 110 lb 6/10/2011 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Death 3/6/2011 63 Male 161 lb 6/16/2011 Physician Japan
Primary
Concomitant
Multi-organ Failure Death 12/10/2010 56 Male 148 lb 6/28/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Dyspnoea Exertional Death 12/3/2010 75 Male 110 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/6/2009 72 Male 130 lb 7/3/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Other Serious 8/7/2009 64 Male 138 lb 7/7/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 7/24/2009 83 Male 114 lb 7/7/2011 Physician Japan
Primary
Concomitant
Rash Death 7/10/2009 63 Male 7/12/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Death 6/8/2011 70 Male 123 lb 7/20/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 5/18/2011 49 Female 8/26/2011 Physician Japan
Primary
Concomitant
Nausea Life Threatening 12/10/2010 56 Male 148 lb 9/7/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Ascites Hospitalization 5/21/2011 70 Female 126 lb 9/7/2011 Physician Italy
Primary
Secondary
Concomitant
Nausea Life Threatening 12/10/2010 56 Male 157 lb 10/6/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Haematemesis Life Threatening 7/1/2011 63 Male 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 11/16/2009 69 Female 154 lb 11/1/2011 Physician Japan
Primary
Concomitant
Nausea Other Serious 4/1/2010 55 Male 115 lb 11/3/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 11/16/2009 69 Female 154 lb 11/3/2011 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 11/16/2009 69 Female 154 lb 11/9/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 3/27/2010 65 Male 165 lb 11/24/2011 Physician Japan
Primary
Concomitant
Confusional State Other Serious 10/6/2011 60 Male 179 lb 11/23/2011 Consumer Brazil
Primary
Concomitant
Adverse Drug Reaction Hospitalization 1/1/2011 62 Male 168 lb 11/28/2011 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/6/2011 63 Male 161 lb 12/26/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/6/2011 63 Male 161 lb 1/6/2012 Physician Japan
Primary
Concomitant
Peritonitis Bacterial Hospitalization 1/13/2012 69 Female 130 lb 1/26/2012 Physician Korea, Republic Of
Primary
Concomitant
Cough Hospitalization 7/2/2011 48 Male 110 lb 2/1/2012 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 12/20/2010 68 Male 357 lb 1/30/2012 Pharmacist Japan
Primary
Concomitant
Gastric Ulcer Life Threatening 7/1/2011 63 Male 126 lb 2/3/2012 Physician Japan
Primary
Secondary
Concomitant
Haematemesis Life Threatening 7/1/2011 63 Male 126 lb 2/9/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Death 9/27/2010 61 Male 106 lb 2/27/2012 Other Health Professional Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/7/2010 61 Female 95 lb 3/6/2012 Physician Japan
Primary
Concomitant
Acute Hepatic Failure Death 2/9/2012 56 Female 128 lb 3/16/2012 Physician Korea, Republic Of
Primary
Concomitant
Hiccups Death 10/6/2011 60 Male 179 lb 3/20/2012 Consumer Brazil
Primary
Concomitant
Cough Hospitalization 7/2/2011 48 Male 110 lb 3/23/2012 Physician Japan
Primary
Concomitant
Sepsis Death 3/27/2011 30 Male 4/10/2012 Physician Philippines
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 11/24/2011 59 Male 141 lb 5/1/2012 Physician Japan
Primary
Concomitant
Portal Vein Thrombosis Other Serious 3/22/2012 64 Male 159 lb 5/2/2012 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 11/24/2011 59 Male 141 lb 5/7/2012 Physician Japan
Primary
Concomitant
Abdominal Pain Disability 9/29/2011 52 Male 93 lb 5/8/2012 Physician Japan
Primary
Concomitant
Nausea Disability 9/29/2011 52 Male 93 lb 5/10/2012 Physician Japan
Primary
Concomitant
Decreased Appetite Death 1/1/2012 77 Female 123 lb 5/10/2012 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 4/20/2012 61 Male 119 lb 5/22/2012 Physician Japan
Primary
Concomitant
Liver Abscess Death 1/1/2011 62 Male 168 lb 5/30/2012 Consumer United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Other Serious 11/24/2011 59 Male 141 lb 6/26/2012 Physician Japan
Primary
Concomitant
Cough Hospitalization 7/2/2011 48 Male 110 lb 6/27/2012 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 9/2/2011 69 Male 355 lb 6/28/2012 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 7/6/2009 72 Male 130 lb 7/18/2012 Physician Japan
Primary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 5/20/2011 58 Male 132 lb 7/20/2012 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 1/1/2012 68 Male 127 lb 8/10/2012 Physician Japan
Primary
Concomitant
Haematocrit Decreased Other Serious 6/29/2012 62 Male 128 lb 8/15/2012 Physician Japan
Primary
Concomitant
Septic Shock Death 6/26/2012 69 Male 8/17/2012 Physician Japan
Primary
Secondary
Hepatic Function Abnormal Death 6/17/2010 35 Male 151 lb 8/27/2012 Physician Japan
Primary
Concomitant
Nausea Death 12/10/2010 56 Male 148 lb 11/30/2012 Physician Tw
Primary
Concomitant
Pyloric Stenosis Other Serious 7/2011 63 Male 126 lb 10/5/2012 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Chlamydial Death 11/24/2011 59 Male 141 lb 12/20/2012 Physician Jp
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 10/2011 67 Male 117 lb 9/4/2012 Physician Jp
Primary
Concomitant

Drug Data